Click here to switch to the map view.

The map label for this gene is htpG [H]

Identifier: 123966216

GI number: 123966216

Start: 880103

End: 882007

Strand: Direct

Name: htpG [H]

Synonym: P9515_09831

Alternate gene names: 123966216

Gene position: 880103-882007 (Clockwise)

Preceding gene: 123966215

Following gene: 123966217

Centisome position: 51.64

GC content: 29.08

Gene sequence:

>1905_bases
ATGGAAAAAGGTGAAATCAGAATTAATACTGAAAATATATTTCCAATAATAAAAAAAGCTGTATATTCAGACCATGAAAT
ATTTTTAAGAGAATTAGTAAGTAATGCGGTAGATGCAATTAGTAAAAGAAGGATGGCCTCAATGGCTGGTGATTGTGAAA
ATTCAGATAAACCTCAGGTCAAAATCACTATTGACAGGGAGAAATCTATATTAAAAATTTCTGATAATGGTATCGGAATG
AATGATGATGAAATTAAAAAATACATAAACCAAGTAGCATTTTCTAGTGCGGAAGAATTTTTAACAAAATACAAGCAAGG
AAATGATGAATTTATAGGTCATTTTGGATTAGGATTTTATTCTAGTTTTATGGTTGCTGACAGAGTTGACATTCTAACCA
AATCAGCAATAAGTGACAGTAAAGCTTTTAATTGGTCATGTGATGGTTCACCTAATTTCACCTTAGAAGAATCTGAGAGA
GATTCAGTTGGGACTGATGTAATCCTTCATTTAATGGATGAAGAGAAAGAGTTTATAGAACCTGAAAGAATTAAATCCTT
AATAAAAAAATATTGTGACTTTATGCCTATAGATGTGCTTTTAGAGGGTGAAATAATTAATAAAAAAAATCCCCCATGGA
GAAAACAACCAAATGAATTAAAAGATGAAGATTATATTGAGCTATACAAATATCTATATCCATTTCAAGGTGATCCTCTC
CTATGGATACATCTAAATACAGATTATCCATACGACATACAAGGAATTTTATATTTTCCAAAACTAACAGGTAGAGCTGA
TTGGGAAAAAGGTGAAATTAAACTATTTTGTAATCAGGTATTTGTAAGCGACTCAATTAAAGAAATTGTACCTAAATATT
TATTACCCTTAAGAGGAGTAATTGATTCAACAGATATACCTTTAAATGTAAGTAGAAGTGCCTTACAAACTGATAGAAAA
GTAAGATCAATTTCATCCTTCATATCAAAAAAAATTGCCAATAAGCTAAAGGATTTACTCAAAAATTCTCCTGAATTTTA
TACACAGATATGGGACTCTATTTCTGCCTTTATTAAGATTGGTGCCATAGAAGACGAAAAGTTTGCTGATCTCGTAGAAA
ATAGTATTATTTTTGAAACAATTATAAATTCAGACAAAGATATAACAAAATATATTGATGATAAATCTCTTATAAAATCT
AATGATAAATTTTACACAACCCTATCAAATTACAAAGATAGAAATAACATTACCGATTCCAAAAAAATTATTTATTGTTC
TGATGTAATTGGTCAATCCAGCGCATTAAATATTTGTCTCTCTGATAACAAAGAAGTGATCAAATCTGATCCATTAATAG
ATGCACAATTTCTTCCATGGATAGAAAGTAAGCATGATAATTATCAATTTCAAAGAGTTGACTCAGAAATAAATGAGCTT
GAAGATAAAGATTCAAAAGAAATTGTTGATAAAGATGGGAAATCAAGCACAGACAATCTAAAGGATATTATTTCAAAAGC
ATTAAATAATGAAAAAGTAACTGTAAAAATTCAATCTCTTACTAATAAAGATGCTCCTCCAGCAATGATATTGTTACCGG
AACAAATGAGAAGAATAAATGATATGGGAGCATACATGGAACAAAAGATGCCTAGCTTACCTGAATATCATGTCCTATTA
ATAAATAAAGAGCATCCTTTAATTTTAGGATTAAGTAATATGACCGGAAGCAAATTAATTCTTGATAAAAAAGATCCAGG
TGAAAACCCTTTAGCATCAAAAATTGCTAATCATGTTTATGACATGGCCAAATTAAGTGTGGGAGGATTAGATCAAGAAC
AAATTATAAATTTGCAAAATAATAATGCCGATTTAATTTCAGATTTACTTAAATCATCAACATAA

Upstream 100 bases:

>100_bases
TATTTGTTAATTCAATATTTTAAGTACGGACAATACTCCTGTTAATGGTTGATTAAGCCGAAAATAGGAAATAAGATTTA
ATAAATTTGTATTTTTAAAA

Downstream 100 bases:

>100_bases
ATAATATGTTAAAATTAGTAATAATATTTATCAAATAATATGTCTAGAGTTTGTGAATTAACTGGAGCAAGAGCGAACAA
TGGGATGGCAGTAAGTCACT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 634; Mature: 634

Protein sequence:

>634_residues
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNAVDAISKRRMASMAGDCENSDKPQVKITIDREKSILKISDNGIGM
NDDEIKKYINQVAFSSAEEFLTKYKQGNDEFIGHFGLGFYSSFMVADRVDILTKSAISDSKAFNWSCDGSPNFTLEESER
DSVGTDVILHLMDEEKEFIEPERIKSLIKKYCDFMPIDVLLEGEIINKKNPPWRKQPNELKDEDYIELYKYLYPFQGDPL
LWIHLNTDYPYDIQGILYFPKLTGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGVIDSTDIPLNVSRSALQTDRK
VRSISSFISKKIANKLKDLLKNSPEFYTQIWDSISAFIKIGAIEDEKFADLVENSIIFETIINSDKDITKYIDDKSLIKS
NDKFYTTLSNYKDRNNITDSKKIIYCSDVIGQSSALNICLSDNKEVIKSDPLIDAQFLPWIESKHDNYQFQRVDSEINEL
EDKDSKEIVDKDGKSSTDNLKDIISKALNNEKVTVKIQSLTNKDAPPAMILLPEQMRRINDMGAYMEQKMPSLPEYHVLL
INKEHPLILGLSNMTGSKLILDKKDPGENPLASKIANHVYDMAKLSVGGLDQEQIINLQNNNADLISDLLKSST

Sequences:

>Translated_634_residues
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNAVDAISKRRMASMAGDCENSDKPQVKITIDREKSILKISDNGIGM
NDDEIKKYINQVAFSSAEEFLTKYKQGNDEFIGHFGLGFYSSFMVADRVDILTKSAISDSKAFNWSCDGSPNFTLEESER
DSVGTDVILHLMDEEKEFIEPERIKSLIKKYCDFMPIDVLLEGEIINKKNPPWRKQPNELKDEDYIELYKYLYPFQGDPL
LWIHLNTDYPYDIQGILYFPKLTGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGVIDSTDIPLNVSRSALQTDRK
VRSISSFISKKIANKLKDLLKNSPEFYTQIWDSISAFIKIGAIEDEKFADLVENSIIFETIINSDKDITKYIDDKSLIKS
NDKFYTTLSNYKDRNNITDSKKIIYCSDVIGQSSALNICLSDNKEVIKSDPLIDAQFLPWIESKHDNYQFQRVDSEINEL
EDKDSKEIVDKDGKSSTDNLKDIISKALNNEKVTVKIQSLTNKDAPPAMILLPEQMRRINDMGAYMEQKMPSLPEYHVLL
INKEHPLILGLSNMTGSKLILDKKDPGENPLASKIANHVYDMAKLSVGGLDQEQIINLQNNNADLISDLLKSST
>Mature_634_residues
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNAVDAISKRRMASMAGDCENSDKPQVKITIDREKSILKISDNGIGM
NDDEIKKYINQVAFSSAEEFLTKYKQGNDEFIGHFGLGFYSSFMVADRVDILTKSAISDSKAFNWSCDGSPNFTLEESER
DSVGTDVILHLMDEEKEFIEPERIKSLIKKYCDFMPIDVLLEGEIINKKNPPWRKQPNELKDEDYIELYKYLYPFQGDPL
LWIHLNTDYPYDIQGILYFPKLTGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGVIDSTDIPLNVSRSALQTDRK
VRSISSFISKKIANKLKDLLKNSPEFYTQIWDSISAFIKIGAIEDEKFADLVENSIIFETIINSDKDITKYIDDKSLIKS
NDKFYTTLSNYKDRNNITDSKKIIYCSDVIGQSSALNICLSDNKEVIKSDPLIDAQFLPWIESKHDNYQFQRVDSEINEL
EDKDSKEIVDKDGKSSTDNLKDIISKALNNEKVTVKIQSLTNKDAPPAMILLPEQMRRINDMGAYMEQKMPSLPEYHVLL
INKEHPLILGLSNMTGSKLILDKKDPGENPLASKIANHVYDMAKLSVGGLDQEQIINLQNNNADLISDLLKSST

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI155722983, Length=636, Percent_Identity=25.7861635220126, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI4507677, Length=656, Percent_Identity=28.5060975609756, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI20149594, Length=200, Percent_Identity=34, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI154146191, Length=200, Percent_Identity=33, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI153792590, Length=200, Percent_Identity=33, Blast_Score=116, Evalue=7e-26,
Organism=Escherichia coli, GI1786679, Length=589, Percent_Identity=29.5415959252971, Blast_Score=227, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI115535205, Length=645, Percent_Identity=27.7519379844961, Blast_Score=236, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI115535167, Length=436, Percent_Identity=31.1926605504587, Blast_Score=231, Evalue=9e-61,
Organism=Caenorhabditis elegans, GI17542208, Length=715, Percent_Identity=26.993006993007, Blast_Score=215, Evalue=7e-56,
Organism=Caenorhabditis elegans, GI17559162, Length=414, Percent_Identity=27.0531400966184, Blast_Score=170, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323840, Length=602, Percent_Identity=27.7408637873754, Blast_Score=193, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6325016, Length=212, Percent_Identity=36.3207547169811, Blast_Score=128, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24586016, Length=665, Percent_Identity=28.7218045112782, Blast_Score=253, Evalue=4e-67,
Organism=Drosophila melanogaster, GI21357739, Length=647, Percent_Identity=27.2024729520866, Blast_Score=196, Evalue=4e-50,
Organism=Drosophila melanogaster, GI17647529, Length=199, Percent_Identity=31.6582914572864, Blast_Score=109, Evalue=5e-24,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72373; Mature: 72373

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNAVDAISKRRMASMAGDCENSDKPQV
CCCCCEEEECHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
KITIDREKSILKISDNGIGMNDDEIKKYINQVAFSSAEEFLTKYKQGNDEFIGHFGLGFY
EEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHH
SSFMVADRVDILTKSAISDSKAFNWSCDGSPNFTLEESERDSVGTDVILHLMDEEKEFIE
HHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEECCCCCCCCCHHHHHHHHHCHHHCCC
PERIKSLIKKYCDFMPIDVLLEGEIINKKNPPWRKQPNELKDEDYIELYKYLYPFQGDPL
HHHHHHHHHHHHCCCCEEEEEECEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCE
LWIHLNTDYPYDIQGILYFPKLTGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGV
EEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHC
IDSTDIPLNVSRSALQTDRKVRSISSFISKKIANKLKDLLKNSPEFYTQIWDSISAFIKI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEE
GAIEDEKFADLVENSIIFETIINSDKDITKYIDDKSLIKSNDKFYTTLSNYKDRNNITDS
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCEEEEHHCCCCCCCCCCC
KKIIYCSDVIGQSSALNICLSDNKEVIKSDPLIDAQFLPWIESKHDNYQFQRVDSEINEL
CEEEEEECCCCCCCEEEEEECCCCHHHHCCCCCCCHHCCHHHCCCCCCHHHHHHHHHHHH
EDKDSKEIVDKDGKSSTDNLKDIISKALNNEKVTVKIQSLTNKDAPPAMILLPEQMRRIN
CCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEECHHHHHHHH
DMGAYMEQKMPSLPEYHVLLINKEHPLILGLSNMTGSKLILDKKDPGENPLASKIANHVY
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHH
DMAKLSVGGLDQEQIINLQNNNADLISDLLKSST
HHHHHCCCCCCHHHEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MEKGEIRINTENIFPIIKKAVYSDHEIFLRELVSNAVDAISKRRMASMAGDCENSDKPQV
CCCCCEEEECHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
KITIDREKSILKISDNGIGMNDDEIKKYINQVAFSSAEEFLTKYKQGNDEFIGHFGLGFY
EEEEECCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHH
SSFMVADRVDILTKSAISDSKAFNWSCDGSPNFTLEESERDSVGTDVILHLMDEEKEFIE
HHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCEECCCCCCCCCHHHHHHHHHCHHHCCC
PERIKSLIKKYCDFMPIDVLLEGEIINKKNPPWRKQPNELKDEDYIELYKYLYPFQGDPL
HHHHHHHHHHHHCCCCEEEEEECEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCE
LWIHLNTDYPYDIQGILYFPKLTGRADWEKGEIKLFCNQVFVSDSIKEIVPKYLLPLRGV
EEEEECCCCCCCCCEEEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHC
IDSTDIPLNVSRSALQTDRKVRSISSFISKKIANKLKDLLKNSPEFYTQIWDSISAFIKI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEE
GAIEDEKFADLVENSIIFETIINSDKDITKYIDDKSLIKSNDKFYTTLSNYKDRNNITDS
CCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCEEEEHHCCCCCCCCCCC
KKIIYCSDVIGQSSALNICLSDNKEVIKSDPLIDAQFLPWIESKHDNYQFQRVDSEINEL
CEEEEEECCCCCCCEEEEEECCCCHHHHCCCCCCCHHCCHHHCCCCCCHHHHHHHHHHHH
EDKDSKEIVDKDGKSSTDNLKDIISKALNNEKVTVKIQSLTNKDAPPAMILLPEQMRRIN
CCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEEEECHHHHHHHH
DMGAYMEQKMPSLPEYHVLLINKEHPLILGLSNMTGSKLILDKKDPGENPLASKIANHVY
HHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHH
DMAKLSVGGLDQEQIINLQNNNADLISDLLKSST
HHHHHCCCCCCHHHEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10722592 [H]