Click here to switch to the map view.

The map label for this gene is rnr [C]

Identifier: 123966182

GI number: 123966182

Start: 841012

End: 842196

Strand: Reverse

Name: rnr [C]

Synonym: P9515_09491

Alternate gene names: 123966182

Gene position: 842196-841012 (Counterclockwise)

Preceding gene: 123966183

Following gene: 123966181

Centisome position: 49.42

GC content: 21.18

Gene sequence:

>1185_bases
TTGAGAGATTTAACTAATTTAAAAACTTTTATTATTGATTCTGAGAATCCCAAAGAGATTGATGATGCTTTCTCTTTAGA
ATTAATAGATGGAAGTAAAAAAAAATTATGGATTCATATTAGCAATCCATGCAAATTATTTTCAACTGATTCAAAAATAG
ATCTTGAGGCAAAAAGTAAGAGCAGTAGTTTATATTTAATTGATCAATATATTCCTATGTTGCCTTCTGAAATAATTGAA
AATGCAAATTTAAATCAAAATAAATTATCAGAAACAATAAGTGCTTCAATAACGTTTAATGAGAATGGTTCAATAAATGA
ATATGAGATGTTAGAGGCGAAAATAATACCTAAATATCAATTAACATACGAAGATGCAGAAGAAATTATTGAATTAGAAC
CTAAAGAAGAATTTGAATTAATAGAAATTAAAAATCTATTACTTAAAAGTCTTAAATATCGAATAACACAAGGTGCAATT
ATTTTTGATATGCCAAGTAATAAAATAGATATTATCGACGGAAATGTCGTGATTAATAATATATATAAAAATGTTTCGCA
AACAATTGTATCTGAATCAATGATATTAATGGGTTATGTCACTAGTTTATTTTTATTTAAAAATAATATAGTTACACCTT
ATAGAACCCAAAAAATAAATTGTGATGTATCTGAGATACTAGCAAAATATAAAAATAGTGATATAAAGTTTTCAATATTA
AAACAATTTATGGGTAAAAGTTATATCACTACAAAGGCTAATAAACATGAATCATTAGGTCTTAAAATGTATACTCAATG
TACTTCACCACTTAGAAGATATTTAGACTTAATTGTTCAAAGACAAGTATTTAATTATATTACAAATAAAAAGGAACTAA
ATATAAATAAGATTAATGAAATAATAGATTTAACAAAGATTAAACAATTAGAGATTAACAATATTTATAAAAATAATAAA
TTAAAATATTTAAATATATTTTTTATTAATGAAAATAAATCATCGTACAAAATAATATTTATTAAATGGATAAATATAAA
AAAAAGTATAGCTTTAGTCTATTTTCAAGAATACTCATTAGAGCTTCTAATAATATTATATATTTCTATAGAAACATATA
CTAATAAAATATATAAAGTTAAATATAATGAAAATGATAATAATCTTTTAGAATTTATTCACTAG

Upstream 100 bases:

>100_bases
GGCTGTAAAAAGAGCAAGAATTGTTGCCTTATTGCCATTTGTTAATCCGGAAGGATAAAAAATTTAAATTTAATAGTTAC
TTAAATAATATTCTAAATAT

Downstream 100 bases:

>100_bases
CTATAAATAAACTCTATATCATAATATTTAGATATTATATTTGTTACTATTAGAAAAAAGATATTATGAGCTTTGTAATT
ACTACCCCATTATATTATGT

Product: ribonuclease II

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRDLTNLKTFIIDSENPKEIDDAFSLELIDGSKKKLWIHISNPCKLFSTDSKIDLEAKSKSSSLYLIDQYIPMLPSEIIE
NANLNQNKLSETISASITFNENGSINEYEMLEAKIIPKYQLTYEDAEEIIELEPKEEFELIEIKNLLLKSLKYRITQGAI
IFDMPSNKIDIIDGNVVINNIYKNVSQTIVSESMILMGYVTSLFLFKNNIVTPYRTQKINCDVSEILAKYKNSDIKFSIL
KQFMGKSYITTKANKHESLGLKMYTQCTSPLRRYLDLIVQRQVFNYITNKKELNINKINEIIDLTKIKQLEINNIYKNNK
LKYLNIFFINENKSSYKIIFIKWINIKKSIALVYFQEYSLELLIILYISIETYTNKIYKVKYNENDNNLLEFIH

Sequences:

>Translated_394_residues
MRDLTNLKTFIIDSENPKEIDDAFSLELIDGSKKKLWIHISNPCKLFSTDSKIDLEAKSKSSSLYLIDQYIPMLPSEIIE
NANLNQNKLSETISASITFNENGSINEYEMLEAKIIPKYQLTYEDAEEIIELEPKEEFELIEIKNLLLKSLKYRITQGAI
IFDMPSNKIDIIDGNVVINNIYKNVSQTIVSESMILMGYVTSLFLFKNNIVTPYRTQKINCDVSEILAKYKNSDIKFSIL
KQFMGKSYITTKANKHESLGLKMYTQCTSPLRRYLDLIVQRQVFNYITNKKELNINKINEIIDLTKIKQLEINNIYKNNK
LKYLNIFFINENKSSYKIIFIKWINIKKSIALVYFQEYSLELLIILYISIETYTNKIYKVKYNENDNNLLEFIH
>Mature_394_residues
MRDLTNLKTFIIDSENPKEIDDAFSLELIDGSKKKLWIHISNPCKLFSTDSKIDLEAKSKSSSLYLIDQYIPMLPSEIIE
NANLNQNKLSETISASITFNENGSINEYEMLEAKIIPKYQLTYEDAEEIIELEPKEEFELIEIKNLLLKSLKYRITQGAI
IFDMPSNKIDIIDGNVVINNIYKNVSQTIVSESMILMGYVTSLFLFKNNIVTPYRTQKINCDVSEILAKYKNSDIKFSIL
KQFMGKSYITTKANKHESLGLKMYTQCTSPLRRYLDLIVQRQVFNYITNKKELNINKINEIIDLTKIKQLEINNIYKNNK
LKYLNIFFINENKSSYKIIFIKWINIKKSIALVYFQEYSLELLIILYISIETYTNKIYKVKYNENDNNLLEFIH

Specific function: 3'-5'Exoribonuclease That Participates In An Essential Cell Function. Acts Nonspecifically On Poly(A), Poly(U) And Ribosomal RNAs. Required For The Expression Of VIrulence Genes In Enteroinvasive Strains Of E.Coli. [C]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribonuclease II (RNB) family [H]

Homologues:

Organism=Escherichia coli, GI87082383, Length=340, Percent_Identity=24.7058823529412, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787542, Length=319, Percent_Identity=22.884012539185, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323943, Length=342, Percent_Identity=29.5321637426901, Blast_Score=96, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001900
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00773 RNB [H]

EC number: 3.1.13.1

Molecular weight: Translated: 46133; Mature: 46133

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: PS01175 RIBONUCLEASE_II ; PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLTNLKTFIIDSENPKEIDDAFSLELIDGSKKKLWIHISNPCKLFSTDSKIDLEAKSK
CCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEECCCEEEEECCCEEEEEECCC
SSSLYLIDQYIPMLPSEIIENANLNQNKLSETISASITFNENGSINEYEMLEAKIIPKYQ
CCCEEEEEHHHCCCCHHHHHCCCCCHHHHHHHEEEEEEECCCCCCCCEEEEEEEECCCEE
LTYEDAEEIIELEPKEEFELIEIKNLLLKSLKYRITQGAIIFDMPSNKIDIIDGNVVINN
ECHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCEEEEECCCCEEEEEECCEEEEH
IYKNVSQTIVSESMILMGYVTSLFLFKNNIVTPYRTQKINCDVSEILAKYKNSDIKFSIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHCCCCEEHHHH
KQFMGKSYITTKANKHESLGLKMYTQCTSPLRRYLDLIVQRQVFNYITNKKELNINKINE
HHHHCCCEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
IIDLTKIKQLEINNIYKNNKLKYLNIFFINENKSSYKIIFIKWINIKKSIALVYFQEYSL
HHHHHHHEEEEECCEECCCCEEEEEEEEEECCCCCEEEEEEEEECCCCEEEEEEEECCCE
ELLIILYISIETYTNKIYKVKYNENDNNLLEFIH
EEEEEEEEEEEEECCEEEEEEECCCCCCHHHCCC
>Mature Secondary Structure
MRDLTNLKTFIIDSENPKEIDDAFSLELIDGSKKKLWIHISNPCKLFSTDSKIDLEAKSK
CCCCCCCEEEEECCCCCCCCCCCEEEEEEECCCEEEEEEECCCEEEEECCCEEEEEECCC
SSSLYLIDQYIPMLPSEIIENANLNQNKLSETISASITFNENGSINEYEMLEAKIIPKYQ
CCCEEEEEHHHCCCCHHHHHCCCCCHHHHHHHEEEEEEECCCCCCCCEEEEEEEECCCEE
LTYEDAEEIIELEPKEEFELIEIKNLLLKSLKYRITQGAIIFDMPSNKIDIIDGNVVINN
ECHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHEECCEEEEECCCCEEEEEECCEEEEH
IYKNVSQTIVSESMILMGYVTSLFLFKNNIVTPYRTQKINCDVSEILAKYKNSDIKFSIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHHHHHHCCCCEEHHHH
KQFMGKSYITTKANKHESLGLKMYTQCTSPLRRYLDLIVQRQVFNYITNKKELNINKINE
HHHHCCCEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
IIDLTKIKQLEINNIYKNNKLKYLNIFFINENKSSYKIIFIKWINIKKSIALVYFQEYSL
HHHHHHHEEEEECCEECCCCEEEEEEEEEECCCCCEEEEEEEEECCCCEEEEEEEECCCE
ELLIILYISIETYTNKIYKVKYNENDNNLLEFIH
EEEEEEEEEEEEECCEEEEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]