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The map label for this gene is typA [H]

Identifier: 123966056

GI number: 123966056

Start: 740166

End: 741968

Strand: Reverse

Name: typA [H]

Synonym: P9515_08211

Alternate gene names: 123966056

Gene position: 741968-740166 (Counterclockwise)

Preceding gene: 123966057

Following gene: 123966055

Centisome position: 43.54

GC content: 34.72

Gene sequence:

>1803_bases
ATGTCAACTTCAATTAAAGATATAAGAAATGTCGCAATTATAGCTCATGTAGATCATGGGAAAACAACCCTTGTCGATGC
ATTATTATCTCAATCAGGAATTTTTAGAGATAACGAAGTAGTTCCTACTTGCGTAATGGACTCGAATGATTTGGAGAGAG
AAAGAGGTATTACAATCCTTTCAAAAAATACAGCTGTTAATTATAAAAACACCCGAATTAATATTATTGACACCCCGGGA
CATGCTGACTTTGGAGGTGAAGTTGAAAGGGTTTTGGGAATGGTTGATGGTTGTTTATTAATCGTTGATGCTAATGAAGG
GCCTATGCCCCAAACAAGGTTTGTATTAAAAAAAGCTTTAGAAAAAGGTCTAAGACCTATAGTCTTCGTAAATAAAATTG
ATAGACCTAGAGTAGTTCCAGAAATAGCAGTTGATAAAGTTCTTGATTTATTCCTTGAATTAGGTGCAGATGATGATCAA
TGCGATTTTCCTTATTTATTCGGTAGTGGATTATCAGGTTTTGCAAAAGAAGAAATGGAGTCAAATAATGATAATATGAT
GCCCCTTTTTGAAGCTATTCTTAGGCATGTTCCTCCACCTGTAGGTGATTTAAATAAGCCATTGCAGCTTCAAATTACAA
CTTTGGATTACTCTGATTTCTTAGGAAGAATTGTAATTGGAAAGATTCATAATGGAACTATAAAAAATGGTCAACAAGCA
AGCCTTATAAAAGAAAGTGGAAAAACTATCAAAGGAAAAGTAAGCAAACTTTTAGGATTTGAGGGATTGCAAAGAATTGA
TATTAATGAAGCTTTTGCCGGAGATATTGTTGCAGTTTCTGGTTTCGATGATGTAAATATTGGAGAGACCATAGCTTGTC
CTGATTCTCCTCATCCACTTCCTTTGATTAAAGTTGATGAGCCTACACTAAATATGACATTTGTCGTAAATGATTCTCCA
TTTGCTGGCAAAGAAGGGAAATTTGTTACAAGCAGACAATTAAAAAATAGATTAGAAAGAGAATTATTAACTAATGTAGC
CCTAAGAGTTGAAGAAACAGATTCACCAGATAGATTTTCTGTCTCTGGGAGAGGCGAACTGCATTTAGGGATTTTGATAG
AAACAATGAGAAGAGAGGGCTTTGAATTCCAAATATCGCAACCGCAAGTTATTTTTAGAGAGATTGATAATGTTCAATGC
GAACCTATAGAAACATTAGTTTTAGATGTTCCAGAAGCCGCAGTTGGTTCTTGCATTGAAAAACTTGGTTCAAGAAAGGC
TGAGATGAAAAACATGCAGACAAGTTCAGATGGAAGAACACAACTAGAATTTCTTGTGCCATCAAGAGGTCTTATAGGCT
TTCGTGGGGAATTTGTGAGAATAACTAGAGGGGAAGGAATTATGAGCCACTCATTCTATGAATATAAACCTAAAGCTGGA
GATTTTGAGACAAGAAGAAATGGTGTACTTATTTCCTTTGAAGAGGGTGTTGCTACATTCTATGCTTTAAAAAATGCAGA
AGATAGAGGTGTTTATTTTATTAAACCGGGAGCAAAGGTTTATAAAGGTATGATTATTGGCGAGAATAATAGATCACAAG
ATTTAGAGTTAAATATTTGCAAAACAAAGCAACTGACAAACATGAGATCTGCAGGAGCAGAAGAATTGGATACTTTACAA
TCTCCTGTAGATATTACACTTGAGAGAGCGCTTGAATATATAGGTCCCGATGAAATGTTAGAAGTAACGCCTGATTCAAT
AAGAATGAGAAAATTAAATAAGAAAAAGGCCTTAAAAAAATAG

Upstream 100 bases:

>100_bases
TTTTATATATGATTTTCAAAGTCTTACAGATAAATTCTTCAGAATAAGCATTCTTTGAGTTAGCCTTAATATAATCAACT
TTTGGTTTGTAAGTTTTTAG

Downstream 100 bases:

>100_bases
TTTCTTATGGGAGATGAAGAAATAAAAAAAAGTTTTGAGGAGAACTTTCTTAATGCTTTAAATCTCTTTAATGATCAAAA
ATGGTATGAGGCTCATGATG

Product: tyrosine binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 600; Mature: 599

Protein sequence:

>600_residues
MSTSIKDIRNVAIIAHVDHGKTTLVDALLSQSGIFRDNEVVPTCVMDSNDLERERGITILSKNTAVNYKNTRINIIDTPG
HADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVFVNKIDRPRVVPEIAVDKVLDLFLELGADDDQ
CDFPYLFGSGLSGFAKEEMESNNDNMMPLFEAILRHVPPPVGDLNKPLQLQITTLDYSDFLGRIVIGKIHNGTIKNGQQA
SLIKESGKTIKGKVSKLLGFEGLQRIDINEAFAGDIVAVSGFDDVNIGETIACPDSPHPLPLIKVDEPTLNMTFVVNDSP
FAGKEGKFVTSRQLKNRLERELLTNVALRVEETDSPDRFSVSGRGELHLGILIETMRREGFEFQISQPQVIFREIDNVQC
EPIETLVLDVPEAAVGSCIEKLGSRKAEMKNMQTSSDGRTQLEFLVPSRGLIGFRGEFVRITRGEGIMSHSFYEYKPKAG
DFETRRNGVLISFEEGVATFYALKNAEDRGVYFIKPGAKVYKGMIIGENNRSQDLELNICKTKQLTNMRSAGAEELDTLQ
SPVDITLERALEYIGPDEMLEVTPDSIRMRKLNKKKALKK

Sequences:

>Translated_600_residues
MSTSIKDIRNVAIIAHVDHGKTTLVDALLSQSGIFRDNEVVPTCVMDSNDLERERGITILSKNTAVNYKNTRINIIDTPG
HADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVFVNKIDRPRVVPEIAVDKVLDLFLELGADDDQ
CDFPYLFGSGLSGFAKEEMESNNDNMMPLFEAILRHVPPPVGDLNKPLQLQITTLDYSDFLGRIVIGKIHNGTIKNGQQA
SLIKESGKTIKGKVSKLLGFEGLQRIDINEAFAGDIVAVSGFDDVNIGETIACPDSPHPLPLIKVDEPTLNMTFVVNDSP
FAGKEGKFVTSRQLKNRLERELLTNVALRVEETDSPDRFSVSGRGELHLGILIETMRREGFEFQISQPQVIFREIDNVQC
EPIETLVLDVPEAAVGSCIEKLGSRKAEMKNMQTSSDGRTQLEFLVPSRGLIGFRGEFVRITRGEGIMSHSFYEYKPKAG
DFETRRNGVLISFEEGVATFYALKNAEDRGVYFIKPGAKVYKGMIIGENNRSQDLELNICKTKQLTNMRSAGAEELDTLQ
SPVDITLERALEYIGPDEMLEVTPDSIRMRKLNKKKALKK
>Mature_599_residues
STSIKDIRNVAIIAHVDHGKTTLVDALLSQSGIFRDNEVVPTCVMDSNDLERERGITILSKNTAVNYKNTRINIIDTPGH
ADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKALEKGLRPIVFVNKIDRPRVVPEIAVDKVLDLFLELGADDDQC
DFPYLFGSGLSGFAKEEMESNNDNMMPLFEAILRHVPPPVGDLNKPLQLQITTLDYSDFLGRIVIGKIHNGTIKNGQQAS
LIKESGKTIKGKVSKLLGFEGLQRIDINEAFAGDIVAVSGFDDVNIGETIACPDSPHPLPLIKVDEPTLNMTFVVNDSPF
AGKEGKFVTSRQLKNRLERELLTNVALRVEETDSPDRFSVSGRGELHLGILIETMRREGFEFQISQPQVIFREIDNVQCE
PIETLVLDVPEAAVGSCIEKLGSRKAEMKNMQTSSDGRTQLEFLVPSRGLIGFRGEFVRITRGEGIMSHSFYEYKPKAGD
FETRRNGVLISFEEGVATFYALKNAEDRGVYFIKPGAKVYKGMIIGENNRSQDLELNICKTKQLTNMRSAGAEELDTLQS
PVDITLERALEYIGPDEMLEVTPDSIRMRKLNKKKALKK

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=488, Percent_Identity=27.2540983606557, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI94966754, Length=139, Percent_Identity=43.1654676258993, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI34147630, Length=299, Percent_Identity=30.7692307692308, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI18390331, Length=145, Percent_Identity=43.448275862069, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI4503483, Length=145, Percent_Identity=37.9310344827586, Blast_Score=103, Evalue=6e-22,
Organism=Homo sapiens, GI25306287, Length=145, Percent_Identity=40, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI19923640, Length=145, Percent_Identity=40, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI25306283, Length=145, Percent_Identity=40, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=43.2432432432432, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=43.2432432432432, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=43.2432432432432, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI217272894, Length=134, Percent_Identity=39.5522388059701, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI217272892, Length=134, Percent_Identity=39.5522388059701, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI94966752, Length=135, Percent_Identity=30.3703703703704, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI53729339, Length=284, Percent_Identity=28.169014084507, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI53729337, Length=284, Percent_Identity=28.169014084507, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI48994988, Length=588, Percent_Identity=54.7619047619048, Blast_Score=646, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=545, Percent_Identity=26.9724770642202, Blast_Score=142, Evalue=7e-35,
Organism=Escherichia coli, GI1789738, Length=143, Percent_Identity=41.958041958042, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790412, Length=298, Percent_Identity=28.5234899328859, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1789737, Length=298, Percent_Identity=28.5234899328859, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1790835, Length=133, Percent_Identity=32.3308270676692, Blast_Score=80, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17557151, Length=232, Percent_Identity=34.4827586206897, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17506493, Length=219, Percent_Identity=32.4200913242009, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17556745, Length=142, Percent_Identity=41.5492957746479, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71988819, Length=131, Percent_Identity=41.2213740458015, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI71988811, Length=131, Percent_Identity=41.2213740458015, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17533571, Length=147, Percent_Identity=45.578231292517, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17556456, Length=285, Percent_Identity=28.7719298245614, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=35.8208955223881, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32566629, Length=262, Percent_Identity=27.4809160305344, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25141371, Length=275, Percent_Identity=26.9090909090909, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994658, Length=154, Percent_Identity=33.7662337662338, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323320, Length=501, Percent_Identity=26.7465069860279, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6324761, Length=274, Percent_Identity=30.6569343065693, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6324707, Length=206, Percent_Identity=33.9805825242718, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320593, Length=206, Percent_Identity=33.9805825242718, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322359, Length=151, Percent_Identity=39.7350993377483, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323098, Length=152, Percent_Identity=39.4736842105263, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=142, Percent_Identity=38.0281690140845, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281363316, Length=303, Percent_Identity=30.3630363036304, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17864358, Length=303, Percent_Identity=30.3630363036304, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI78706572, Length=527, Percent_Identity=25.0474383301708, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24585711, Length=166, Percent_Identity=35.5421686746988, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24585713, Length=166, Percent_Identity=35.5421686746988, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24585709, Length=150, Percent_Identity=38.6666666666667, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI28574573, Length=199, Percent_Identity=34.6733668341709, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24582462, Length=136, Percent_Identity=44.1176470588235, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19921738, Length=275, Percent_Identity=30.9090909090909, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI221458488, Length=131, Percent_Identity=43.5114503816794, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI21357743, Length=190, Percent_Identity=36.3157894736842, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 66676; Mature: 66545

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSIKDIRNVAIIAHVDHGKTTLVDALLSQSGIFRDNEVVPTCVMDSNDLERERGITIL
CCCCHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHCCEEEE
SKNTAVNYKNTRINIIDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKAL
ECCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EKGLRPIVFVNKIDRPRVVPEIAVDKVLDLFLELGADDDQCDFPYLFGSGLSGFAKEEME
HHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHH
SNNDNMMPLFEAILRHVPPPVGDLNKPLQLQITTLDYSDFLGRIVIGKIHNGTIKNGQQA
CCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHCEEEEEEECCCCCCCCCHH
SLIKESGKTIKGKVSKLLGFEGLQRIDINEAFAGDIVAVSGFDDVNIGETIACPDSPHPL
HHHHHCCCCHHHHHHHHHCCCCCEEECCCCCCCCCEEEECCCCCCCCCCEEECCCCCCCE
PLIKVDEPTLNMTFVVNDSPFAGKEGKFVTSRQLKNRLERELLTNVALRVEETDSPDRFS
EEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
VSGRGELHLGILIETMRREGFEFQISQPQVIFREIDNVQCEPIETLVLDVPEAAVGSCIE
ECCCCCEEEHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHH
KLGSRKAEMKNMQTSSDGRTQLEFLVPSRGLIGFRGEFVRITRGEGIMSHSFYEYKPKAG
HHCCCHHHHHHCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCCCCCCCCEEECCCCC
DFETRRNGVLISFEEGVATFYALKNAEDRGVYFIKPGAKVYKGMIIGENNRSQDLELNIC
CCCCCCCCEEEEECCCCEEEEEECCCCCCCEEEECCCHHHHEEEEEECCCCCCCEEEEEE
KTKQLTNMRSAGAEELDTLQSPVDITLERALEYIGPDEMLEVTPDSIRMRKLNKKKALKK
CCHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STSIKDIRNVAIIAHVDHGKTTLVDALLSQSGIFRDNEVVPTCVMDSNDLERERGITIL
CCCHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHCCEEEE
SKNTAVNYKNTRINIIDTPGHADFGGEVERVLGMVDGCLLIVDANEGPMPQTRFVLKKAL
ECCEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EKGLRPIVFVNKIDRPRVVPEIAVDKVLDLFLELGADDDQCDFPYLFGSGLSGFAKEEME
HHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCHHHHHHHH
SNNDNMMPLFEAILRHVPPPVGDLNKPLQLQITTLDYSDFLGRIVIGKIHNGTIKNGQQA
CCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECHHHHHCEEEEEEECCCCCCCCCHH
SLIKESGKTIKGKVSKLLGFEGLQRIDINEAFAGDIVAVSGFDDVNIGETIACPDSPHPL
HHHHHCCCCHHHHHHHHHCCCCCEEECCCCCCCCCEEEECCCCCCCCCCEEECCCCCCCE
PLIKVDEPTLNMTFVVNDSPFAGKEGKFVTSRQLKNRLERELLTNVALRVEETDSPDRFS
EEEEECCCCEEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHEEEEECCCCCCEEE
VSGRGELHLGILIETMRREGFEFQISQPQVIFREIDNVQCEPIETLVLDVPEAAVGSCIE
ECCCCCEEEHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHH
KLGSRKAEMKNMQTSSDGRTQLEFLVPSRGLIGFRGEFVRITRGEGIMSHSFYEYKPKAG
HHCCCHHHHHHCCCCCCCCEEEEEEECCCCCEEECCCEEEEECCCCCCCCCCEEECCCCC
DFETRRNGVLISFEEGVATFYALKNAEDRGVYFIKPGAKVYKGMIIGENNRSQDLELNIC
CCCCCCCCEEEEECCCCEEEEEECCCCCCCEEEECCCHHHHEEEEEECCCCCCCEEEEEE
KTKQLTNMRSAGAEELDTLQSPVDITLERALEYIGPDEMLEVTPDSIRMRKLNKKKALKK
CCHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]