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The map label for this gene is purQ [H]

Identifier: 123966037

GI number: 123966037

Start: 724548

End: 725210

Strand: Reverse

Name: purQ [H]

Synonym: P9515_08021

Alternate gene names: 123966037

Gene position: 725210-724548 (Counterclockwise)

Preceding gene: 123966038

Following gene: 123966019

Centisome position: 42.55

GC content: 31.98

Gene sequence:

>663_bases
ATGGCTTGTTTTACTGTTGGAATTGTTGTCTTCCCTGGATCTAATTGTGATCGTGATGTTGCATGGGCTTTAGAAGCTTG
TTTAGACATTAAAACAAAATTCTTATGGCATGAATCATCTGATTTAAATGAAATTGATGCAATCGTTTTGCCAGGAGGAT
TTAGTTATGGTGATTATTTAAGGTGCGGAGCAATTGCAAGATTTTCCCCATTAATAAATTCTTTAAATGATTTTGTTAAA
AGTGGTAGACGAGTATTAGGTATATGTAATGGTTTTCAGATTTTGACTGAGTCAGGTTTTCTTCCCGGAGCTCTTGTTGC
TAATAAAAATCTCAATTTTATTTGTGATGATGCTGATTTGAATGTGATTACTTCAAAAGGCGGTTGGTTTAAAAATTCAG
ATGAAACACAAAAAATTAAATTACCAATAGCTCATGGAGAAGGACGTTATCATTGCGATCAAAATACACTAAAAAAACTT
ATTGATAATGATTTAATTGCACTAAGATACAAAAATAATCCAAACGGTTCAACTTTTGATATTGCAGGCATAACTAATGA
AAAAGGAAATGTTTTAGGATTAATGCCTCATCCTGAAAGAGCATGTGATGAAGTTATTGGTGGAACAGATGGACTATATA
CTTTGAAGTCATTAATGATTTAA

Upstream 100 bases:

>100_bases
TAAAGAGGGTGATATTAAAGAAAAAATTGATATATTATGCGATCGATTATTTGCTAATACAGTAATTGAAGACTTTGAAT
ACTCAATAAAAAAATTATAA

Downstream 100 bases:

>100_bases
TTAATAAAAAAAAAGACCTTCATATATTGAAGGTCTTTTTTATTTGGGAATAACTTATTGAACTAAACTTTTGCTTTTAC
CTTTGAACCTAAGTTACCTT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 220; Mature: 219

Protein sequence:

>220_residues
MACFTVGIVVFPGSNCDRDVAWALEACLDIKTKFLWHESSDLNEIDAIVLPGGFSYGDYLRCGAIARFSPLINSLNDFVK
SGRRVLGICNGFQILTESGFLPGALVANKNLNFICDDADLNVITSKGGWFKNSDETQKIKLPIAHGEGRYHCDQNTLKKL
IDNDLIALRYKNNPNGSTFDIAGITNEKGNVLGLMPHPERACDEVIGGTDGLYTLKSLMI

Sequences:

>Translated_220_residues
MACFTVGIVVFPGSNCDRDVAWALEACLDIKTKFLWHESSDLNEIDAIVLPGGFSYGDYLRCGAIARFSPLINSLNDFVK
SGRRVLGICNGFQILTESGFLPGALVANKNLNFICDDADLNVITSKGGWFKNSDETQKIKLPIAHGEGRYHCDQNTLKKL
IDNDLIALRYKNNPNGSTFDIAGITNEKGNVLGLMPHPERACDEVIGGTDGLYTLKSLMI
>Mature_219_residues
ACFTVGIVVFPGSNCDRDVAWALEACLDIKTKFLWHESSDLNEIDAIVLPGGFSYGDYLRCGAIARFSPLINSLNDFVKS
GRRVLGICNGFQILTESGFLPGALVANKNLNFICDDADLNVITSKGGWFKNSDETQKIKLPIAHGEGRYHCDQNTLKKLI
DNDLIALRYKNNPNGSTFDIAGITNEKGNVLGLMPHPERACDEVIGGTDGLYTLKSLMI

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=197, Percent_Identity=31.4720812182741, Blast_Score=72, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=237, Percent_Identity=27.8481012658228, Blast_Score=73, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582111, Length=236, Percent_Identity=29.6610169491525, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24582109, Length=236, Percent_Identity=29.6610169491525, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI17137292, Length=236, Percent_Identity=29.6610169491525, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 24064; Mature: 23933

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACFTVGIVVFPGSNCDRDVAWALEACLDIKTKFLWHESSDLNEIDAIVLPGGFSYGDYL
CCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEECCCCCCCCHH
RCGAIARFSPLINSLNDFVKSGRRVLGICNGFQILTESGFLPGALVANKNLNFICDDADL
HHCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCCCCEEEECCCCCEEECCCCC
NVITSKGGWFKNSDETQKIKLPIAHGEGRYHCDQNTLKKLIDNDLIALRYKNNPNGSTFD
EEEECCCCCCCCCCCCEEEEEEEECCCCEEECCHHHHHHHHCCCEEEEEECCCCCCCEEE
IAGITNEKGNVLGLMPHPERACDEVIGGTDGLYTLKSLMI
EEEEECCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHCC
>Mature Secondary Structure 
ACFTVGIVVFPGSNCDRDVAWALEACLDIKTKFLWHESSDLNEIDAIVLPGGFSYGDYL
CEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCCCEEEECCCCCCCCHH
RCGAIARFSPLINSLNDFVKSGRRVLGICNGFQILTESGFLPGALVANKNLNFICDDADL
HHCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEECCCCCCCEEEECCCCCEEECCCCC
NVITSKGGWFKNSDETQKIKLPIAHGEGRYHCDQNTLKKLIDNDLIALRYKNNPNGSTFD
EEEECCCCCCCCCCCCEEEEEEEECCCCEEECCHHHHHHHHCCCEEEEEECCCCCCCEEE
IAGITNEKGNVLGLMPHPERACDEVIGGTDGLYTLKSLMI
EEEEECCCCCEEEECCCCHHHHHHHHCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]