Click here to switch to the map view.

The map label for this gene is rfbG [H]

Identifier: 123965996

GI number: 123965996

Start: 691557

End: 692639

Strand: Direct

Name: rfbG [H]

Synonym: P9515_07611

Alternate gene names: 123965996

Gene position: 691557-692639 (Clockwise)

Preceding gene: 123965995

Following gene: 123965997

Centisome position: 40.58

GC content: 30.93

Gene sequence:

>1083_bases
ATGGTAAATATAAACTTAGATTTTTGGAAGGACAAGAAAGTAATCATTACTGGACATACTGGTTTCAAAGGAAGTTGGCT
GCTTATTTGGCTTATTACACTTGGTGCTGAAGTTTATGGAATATCTATTTCAGAAGGAGAAGAAAGTAACTTATTTAATT
CTATAAAAAGAAATATATCTAATAAATTTGATCATAAATTAATAGACATTAGAGATTTAGGAAAAGTCTCTAACGCTATC
TCTCAAATCAAGCCAGATATAATAGTTCATATGGCTGCTCAAGCATTAGTACAAGAAAGTTATAAAGATCCGATAACAAC
TTGGTCTACAAATCTTATGGGTACCATCAATTTATTAGAAAGCGTTAGCAAAATTAAGAATCATTGCGCTTTAGTTTGCG
TCACAACAGACAAAGTTTACGAAAACAAAAATTGGTGTTATGGATATAGAGAGAATGATAACTTAGGTGGTGCAGATCCT
TATAGTGCAAGCAAAGCGGCTGCAGAAATAGCTATTAAAAGTTGGAGAAAAAGTTATTGTGGAGAAAATAATTTCGAAAT
ATCTAACCTTGGAATTGCGACAGCAAGAGCAGGAAATGTTATTGGGGGTGGAGACTATGCTGAAAATAGATTAATTCCTG
ATTGTTATAGAGCATATGTCAAAGAAAATATAATTAAAGTGAGAAATCCTAATTCAATTAGACCATGGCAATTTGTACTT
GAACCATTGTACGGTTACCTTTTATTAGCTGAAAGACTGTATCTAGATCCTAAAAACTATTCATCAGAATATAATTTTGG
TCCGAATAATGACAGTAACAAGACTGTCTTAGAAGTTGTTAAGCACATATCTTCTTGTTGGAAAGTTAGTTATGCTGTTC
AACAGGAAAATGATTTTTTTCAAGAAGCAAATATATTAAATTTAGATGTATCTAAATCAAAACAAGTTCTGCAATGGGAA
CCTATATGGGACTTTGAACAGTCCTTAAATAAGACAGTAAATTGGTATAAAAATATAAAGTTAGGAGGAGATCCATATAA
AGAATGCTTGAATAATATAAATTCTTTTCAAACTGAAAATTAA

Upstream 100 bases:

>100_bases
AAGCATTTACTCATAATGGATTTTGGCATCCTATGGATACATTAAGAGATAAGAATTATCTAAATACATTATGGAATGAA
AATAGAGCACCTTGGAAAAT

Downstream 100 bases:

>100_bases
TTTATTAAAGTCTTTAATTTTTATAAATTAGAATTATAGATAAATTAATAATTTATCCTATGAAATTATTTATAACTGGT
GCGAATGGGACTATTGGCTC

Product: CDP-glucose 4,6-dehydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MVNINLDFWKDKKVIITGHTGFKGSWLLIWLITLGAEVYGISISEGEESNLFNSIKRNISNKFDHKLIDIRDLGKVSNAI
SQIKPDIIVHMAAQALVQESYKDPITTWSTNLMGTINLLESVSKIKNHCALVCVTTDKVYENKNWCYGYRENDNLGGADP
YSASKAAAEIAIKSWRKSYCGENNFEISNLGIATARAGNVIGGGDYAENRLIPDCYRAYVKENIIKVRNPNSIRPWQFVL
EPLYGYLLLAERLYLDPKNYSSEYNFGPNNDSNKTVLEVVKHISSCWKVSYAVQQENDFFQEANILNLDVSKSKQVLQWE
PIWDFEQSLNKTVNWYKNIKLGGDPYKECLNNINSFQTEN

Sequences:

>Translated_360_residues
MVNINLDFWKDKKVIITGHTGFKGSWLLIWLITLGAEVYGISISEGEESNLFNSIKRNISNKFDHKLIDIRDLGKVSNAI
SQIKPDIIVHMAAQALVQESYKDPITTWSTNLMGTINLLESVSKIKNHCALVCVTTDKVYENKNWCYGYRENDNLGGADP
YSASKAAAEIAIKSWRKSYCGENNFEISNLGIATARAGNVIGGGDYAENRLIPDCYRAYVKENIIKVRNPNSIRPWQFVL
EPLYGYLLLAERLYLDPKNYSSEYNFGPNNDSNKTVLEVVKHISSCWKVSYAVQQENDFFQEANILNLDVSKSKQVLQWE
PIWDFEQSLNKTVNWYKNIKLGGDPYKECLNNINSFQTEN
>Mature_360_residues
MVNINLDFWKDKKVIITGHTGFKGSWLLIWLITLGAEVYGISISEGEESNLFNSIKRNISNKFDHKLIDIRDLGKVSNAI
SQIKPDIIVHMAAQALVQESYKDPITTWSTNLMGTINLLESVSKIKNHCALVCVTTDKVYENKNWCYGYRENDNLGGADP
YSASKAAAEIAIKSWRKSYCGENNFEISNLGIATARAGNVIGGGDYAENRLIPDCYRAYVKENIIKVRNPNSIRPWQFVL
EPLYGYLLLAERLYLDPKNYSSEYNFGPNNDSNKTVLEVVKHISSCWKVSYAVQQENDFFQEANILNLDVSKSKQVLQWE
PIWDFEQSLNKTVNWYKNIKLGGDPYKECLNNINSFQTEN

Specific function: INVOLVED IN THE SYNTHESIS OF ENTEROBACTERIAL COMMON ANTIGEN (ECA) AND REQUIRED FOR SYNTHESIS OF LIPOPOLYSACCHARIDE O-SIDE CHAINS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI42516563, Length=334, Percent_Identity=24.251497005988, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI7657641, Length=351, Percent_Identity=24.2165242165242, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI48994969, Length=347, Percent_Identity=24.207492795389, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788353, Length=355, Percent_Identity=23.6619718309859, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI115532424, Length=356, Percent_Identity=23.5955056179775, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356223, Length=353, Percent_Identity=23.2294617563739, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013445
- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =4.2.1.45 [H]

Molecular weight: Translated: 41013; Mature: 41013

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNINLDFWKDKKVIITGHTGFKGSWLLIWLITLGAEVYGISISEGEESNLFNSIKRNIS
CEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHH
NKFDHKLIDIRDLGKVSNAISQIKPDIIVHMAAQALVQESYKDPITTWSTNLMGTINLLE
HHHHHHEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
SVSKIKNHCALVCVTTDKVYENKNWCYGYRENDNLGGADPYSASKAAAEIAIKSWRKSYC
HHHHHHHCEEEEEEECHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GENNFEISNLGIATARAGNVIGGGDYAENRLIPDCYRAYVKENIIKVRNPNSIRPWQFVL
CCCCCEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCEEEECCCCCCCHHHHHH
EPLYGYLLLAERLYLDPKNYSSEYNFGPNNDSNKTVLEVVKHISSCWKVSYAVQQENDFF
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
QEANILNLDVSKSKQVLQWEPIWDFEQSLNKTVNWYKNIKLGGDPYKECLNNINSFQTEN
HHCCEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVNINLDFWKDKKVIITGHTGFKGSWLLIWLITLGAEVYGISISEGEESNLFNSIKRNIS
CEEEEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHHH
NKFDHKLIDIRDLGKVSNAISQIKPDIIVHMAAQALVQESYKDPITTWSTNLMGTINLLE
HHHHHHEECHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
SVSKIKNHCALVCVTTDKVYENKNWCYGYRENDNLGGADPYSASKAAAEIAIKSWRKSYC
HHHHHHHCEEEEEEECHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GENNFEISNLGIATARAGNVIGGGDYAENRLIPDCYRAYVKENIIKVRNPNSIRPWQFVL
CCCCCEEECCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCEEEECCCCCCCHHHHHH
EPLYGYLLLAERLYLDPKNYSSEYNFGPNNDSNKTVLEVVKHISSCWKVSYAVQQENDFF
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
QEANILNLDVSKSKQVLQWEPIWDFEQSLNKTVNWYKNIKLGGDPYKECLNNINSFQTEN
HHCCEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609 [H]