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The map label for this gene is argB [H]

Identifier: 123965798

GI number: 123965798

Start: 504361

End: 505212

Strand: Reverse

Name: argB [H]

Synonym: P9515_05631

Alternate gene names: 123965798

Gene position: 505212-504361 (Counterclockwise)

Preceding gene: 123965799

Following gene: 123965797

Centisome position: 29.65

GC content: 36.27

Gene sequence:

>852_bases
ATGGATGATTCTCTAAGAGTATCAATATTAAGCGAGGCACTTCCATACATACAAAGTTTTTCAGGTAGAAAAATTGTTGT
TAAGTATGGTGGTTCCATTATGGAAGATGAAAAATTAAAAAAAGCTTTCTTCCGAGATATTGCTCTTTTATCAAGTGTTG
GTGTATGTCCAGTAGTTATACATGGGGGTGGTCCCGAAATCAATCGATGGCTTAGCAAATTAGAAATATCTCCAAAATTT
GAGAAGGGGCTAAGAGTTACAGATGATAAAACAATGGAAATAGTTGAGATGGTGCTTATGGGAAGAGTAAATAAACAGAT
TGTGAGAGGAATCAACAAAACAGGCTCATTAGCTGTAGGTATTTCAGGACTCGATGGGAACTTAATTCAGTCGAGAGAAT
TAGGAGATGGGAGTCATGGATTAGTTGGAGAAGTCACACAAATCAACCCTGAATTATTAGAACCTCTTATTGCGAAAGGA
TATATTCCTGTCATATCAAGTATTGGCTCTACAACAGATGGCATTTCCCATAACATCAATGCAGATTTCGTTGCAGGTGA
ACTTGCTGCTGCAATAAATGCCGAAAAACTTATTCTTCTAACTGATACTCCGGGGATACTAAAAGAAAGAAATAACCCAA
ATAGTCTCGCAAAACAAATCAACCTAAAAGAAGCCAGAAAATTTATTGAAAAGAATATTGTTTCTAATGGGATGCTCCCA
AAAACCGAATGTTGTATTAGAGCCTTAGCTCAAGGAGTAAGAGCTGCTCACATAATTGATGGAAGAATTGAGCATTCATT
ACTTCTAGAAATTTTCACAAACTCAGGGATTGGAACAATGATTAATGCTTGA

Upstream 100 bases:

>100_bases
ATAAAAAGGAATTCGATTTGATTTTCTTTTATTAAATATTGGAATATATTTAGGAAAATTCAATTAATTAATTAAATCAA
ATTTCAATATTCTTGTCATT

Downstream 100 bases:

>100_bases
TAATGGATTCATACAAGCAAGTTGTTGAGACAGCAGAGTTTGCTCTTATTAAAGGTGAATATAGTTTCTGTATTGAATAT
TTATACCCAATAATCGAATC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MDDSLRVSILSEALPYIQSFSGRKIVVKYGGSIMEDEKLKKAFFRDIALLSSVGVCPVVIHGGGPEINRWLSKLEISPKF
EKGLRVTDDKTMEIVEMVLMGRVNKQIVRGINKTGSLAVGISGLDGNLIQSRELGDGSHGLVGEVTQINPELLEPLIAKG
YIPVISSIGSTTDGISHNINADFVAGELAAAINAEKLILLTDTPGILKERNNPNSLAKQINLKEARKFIEKNIVSNGMLP
KTECCIRALAQGVRAAHIIDGRIEHSLLLEIFTNSGIGTMINA

Sequences:

>Translated_283_residues
MDDSLRVSILSEALPYIQSFSGRKIVVKYGGSIMEDEKLKKAFFRDIALLSSVGVCPVVIHGGGPEINRWLSKLEISPKF
EKGLRVTDDKTMEIVEMVLMGRVNKQIVRGINKTGSLAVGISGLDGNLIQSRELGDGSHGLVGEVTQINPELLEPLIAKG
YIPVISSIGSTTDGISHNINADFVAGELAAAINAEKLILLTDTPGILKERNNPNSLAKQINLKEARKFIEKNIVSNGMLP
KTECCIRALAQGVRAAHIIDGRIEHSLLLEIFTNSGIGTMINA
>Mature_283_residues
MDDSLRVSILSEALPYIQSFSGRKIVVKYGGSIMEDEKLKKAFFRDIALLSSVGVCPVVIHGGGPEINRWLSKLEISPKF
EKGLRVTDDKTMEIVEMVLMGRVNKQIVRGINKTGSLAVGISGLDGNLIQSRELGDGSHGLVGEVTQINPELLEPLIAKG
YIPVISSIGSTTDGISHNINADFVAGELAAAINAEKLILLTDTPGILKERNNPNSLAKQINLKEARKFIEKNIVSNGMLP
KTECCIRALAQGVRAAHIIDGRIEHSLLLEIFTNSGIGTMINA

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1789181, Length=284, Percent_Identity=27.4647887323944, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693208, Length=260, Percent_Identity=31.1538461538462, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320913, Length=274, Percent_Identity=29.5620437956204, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004662
- InterPro:   IPR001048 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.8 [H]

Molecular weight: Translated: 30550; Mature: 30550

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDSLRVSILSEALPYIQSFSGRKIVVKYGGSIMEDEKLKKAFFRDIALLSSVGVCPVVI
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
HGGGPEINRWLSKLEISPKFEKGLRVTDDKTMEIVEMVLMGRVNKQIVRGINKTGSLAVG
ECCCHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
ISGLDGNLIQSRELGDGSHGLVGEVTQINPELLEPLIAKGYIPVISSIGSTTDGISHNIN
EECCCCCEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCC
ADFVAGELAAAINAEKLILLTDTPGILKERNNPNSLAKQINLKEARKFIEKNIVSNGMLP
CHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCC
KTECCIRALAQGVRAAHIIDGRIEHSLLLEIFTNSGIGTMINA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDDSLRVSILSEALPYIQSFSGRKIVVKYGGSIMEDEKLKKAFFRDIALLSSVGVCPVVI
CCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEE
HGGGPEINRWLSKLEISPKFEKGLRVTDDKTMEIVEMVLMGRVNKQIVRGINKTGSLAVG
ECCCHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
ISGLDGNLIQSRELGDGSHGLVGEVTQINPELLEPLIAKGYIPVISSIGSTTDGISHNIN
EECCCCCEEECCCCCCCCCCCCCHHHHCCHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCC
ADFVAGELAAAINAEKLILLTDTPGILKERNNPNSLAKQINLKEARKFIEKNIVSNGMLP
CHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCC
KTECCIRALAQGVRAAHIIDGRIEHSLLLEIFTNSGIGTMINA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]