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The map label for this gene is thyX [H]

Identifier: 123965511

GI number: 123965511

Start: 256089

End: 256727

Strand: Reverse

Name: thyX [H]

Synonym: P9515_02761

Alternate gene names: 123965511

Gene position: 256727-256089 (Counterclockwise)

Preceding gene: 123965512

Following gene: 123965509

Centisome position: 15.06

GC content: 31.61

Gene sequence:

>639_bases
ATGAGTAGAGTTGAGCTTATTACACTAACTCCAGATGCGGAAAAAACAATGGCTTTTATAGCCAGAGTTTCTAATCCTTC
TAATCAAGATAATGATAAATTTGCAGGATTATTAAGATATTGTATTCAACATGAGCACTGGTCTGTTTTTGAGCAATCAT
GTATGACATTAAAAATTGAGACTAATAGAGGTATAGCTGCTCAAATTCTTAGACATAGATCATTTACTTTTCAAGAATTC
TCCCAAAGATATGCAGAAACTAATTTACTAGGAAATGACATTCCTATCCCAGAATTAAGGAGACAAGATAAAAAGAATCG
TCAAAATAGTATGGATGATATACCTAATGAAGTTAAAAGCAAATTTTCAGAAAAAATTGAAAAACATTTTCAAGAGGCAA
ATAATTTATATGAAGAAATGCTTAATGCAGGGATAGCAAAGGAATGTGCAAGATTTATTATGCCATTGGCTACTCCAACC
AGAATTTATATGACAGGTTCCTGTAGGTCTTGGATTCACTATATACAATTAAGATCAAAAGAAGGAACGCAAAAAGAACA
TATGGAAATAGCTGAAGATTGTAAGACAGTATTTATCAAATCTTTTCCATCTGTATCTGAAGCACTGAATTGGGAATAA

Upstream 100 bases:

>100_bases
CTATTGTTTTTTGAGGGTGATCCCTGTTCTACAACGTATGAAGATAGGAAAGGTAAATATCAAAATCAACCAGAACAAGT
AACTTTAGCCAAAATTTAAA

Downstream 100 bases:

>100_bases
AATTATCCGTGACTTCTTGGAGAAGTCTGATAATTTTTGTTGTCTCTGATCTTAGAAAATTCAGTATTTAAAATTTGTAG
ATTACTTTGAGAATGTTCAT

Product: FAD-dependent thymidylate synthase

Products: NA

Alternate protein names: TS; TSase [H]

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MSRVELITLTPDAEKTMAFIARVSNPSNQDNDKFAGLLRYCIQHEHWSVFEQSCMTLKIETNRGIAAQILRHRSFTFQEF
SQRYAETNLLGNDIPIPELRRQDKKNRQNSMDDIPNEVKSKFSEKIEKHFQEANNLYEEMLNAGIAKECARFIMPLATPT
RIYMTGSCRSWIHYIQLRSKEGTQKEHMEIAEDCKTVFIKSFPSVSEALNWE

Sequences:

>Translated_212_residues
MSRVELITLTPDAEKTMAFIARVSNPSNQDNDKFAGLLRYCIQHEHWSVFEQSCMTLKIETNRGIAAQILRHRSFTFQEF
SQRYAETNLLGNDIPIPELRRQDKKNRQNSMDDIPNEVKSKFSEKIEKHFQEANNLYEEMLNAGIAKECARFIMPLATPT
RIYMTGSCRSWIHYIQLRSKEGTQKEHMEIAEDCKTVFIKSFPSVSEALNWE
>Mature_211_residues
SRVELITLTPDAEKTMAFIARVSNPSNQDNDKFAGLLRYCIQHEHWSVFEQSCMTLKIETNRGIAAQILRHRSFTFQEFS
QRYAETNLLGNDIPIPELRRQDKKNRQNSMDDIPNEVKSKFSEKIEKHFQEANNLYEEMLNAGIAKECARFIMPLATPTR
IYMTGSCRSWIHYIQLRSKEGTQKEHMEIAEDCKTVFIKSFPSVSEALNWE

Specific function: Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate [H]

COG id: COG1351

COG function: function code F; Predicted alternative thymidylate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thyX (flavin-dependent thymidylate synthase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003669 [H]

Pfam domain/function: PF02511 Thy1 [H]

EC number: =2.1.1.148 [H]

Molecular weight: Translated: 24729; Mature: 24598

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRVELITLTPDAEKTMAFIARVSNPSNQDNDKFAGLLRYCIQHEHWSVFEQSCMTLKIE
CCCEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
TNRGIAAQILRHRSFTFQEFSQRYAETNLLGNDIPIPELRRQDKKNRQNSMDDIPNEVKS
CCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHCCHHHHHH
KFSEKIEKHFQEANNLYEEMLNAGIAKECARFIMPLATPTRIYMTGSCRSWIHYIQLRSK
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCC
EGTQKEHMEIAEDCKTVFIKSFPSVSEALNWE
CCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure 
SRVELITLTPDAEKTMAFIARVSNPSNQDNDKFAGLLRYCIQHEHWSVFEQSCMTLKIE
CCEEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
TNRGIAAQILRHRSFTFQEFSQRYAETNLLGNDIPIPELRRQDKKNRQNSMDDIPNEVKS
CCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHCCHHHHHH
KFSEKIEKHFQEANNLYEEMLNAGIAKECARFIMPLATPTRIYMTGSCRSWIHYIQLRSK
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCC
EGTQKEHMEIAEDCKTVFIKSFPSVSEALNWE
CCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]