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The map label for this gene is pdxA [H]

Identifier: 123965262

GI number: 123965262

Start: 28329

End: 29369

Strand: Reverse

Name: pdxA [H]

Synonym: P9515_00271

Alternate gene names: 123965262

Gene position: 29369-28329 (Counterclockwise)

Preceding gene: 123965263

Following gene: 123965259

Centisome position: 1.72

GC content: 32.66

Gene sequence:

>1041_bases
ATGAGTAATAAACGTAATACTATTGATGATCGCTTGAAAGTTATTATCAGTGTTGGAGATGATTCAGGTATTGGACCTGA
AATCATATTAAAGGCTCTTAGTTCAAAGGAAATTCCCAATAATATTGATACATTAATTGTGGGATCAAAAATAAACTTAA
AAAATACGTATAAAAAACTTAAATCTTTAGGAGTACAAAATATTGTCGATCCAAGCAATTATCAAATACATGATATAGAA
ATTCCTTTTGAAATTAATAAACCAAAACAAAGCAATGGAAATTCAAGTTTTTTTTATTTAAAAAAAGCCATTGAAATTGT
CCAAAAATATCGAAATGCAGCTTTAGTTACTGGACCTATTTGTAAAAAGTCATGGGCTTTGGCAGGTCATAATTATTCTG
GTCAAACTGAGTTATTGGCTGAATCTTGTCAGGTAAATAATTTTGGTATGTTGTTTACCGCTAAATCTCCAATAACTAAT
TGGAGGTTTAACACTTTATTAGCGACAACCCATATCCCCCTTTGTGAAGTCCCAAAACAATTGTCAACTAAATTAATTCA
TTCAAAATTAAATTTGCTTGCGACATTTTGTAAGAATTATGTTGAAAAACCGATTCTAAAAATTGCTGGGTTAAATCCAC
ATGCCGGTGAAGAAGGAATATTAGGAAGCGAAGAGCATGATTGGATCAATGATGCCGTGAATAGCTGGAGCGAACAAAAC
AAGGATGTTCACTTATTAGGTCCAATTTCTCCAGATACTTGCTGGAATTCATCAGCAAAAGCTTGGAGAGAGGATAAAGC
TCCAACACATAATGGAATTCTTGCTATGTATCATGATCAAGGATTAATTCCAATTAAAGTTATAGCTCTTAATTACTCAG
TTAACACAACCCTAGGTTTACCTTTTATTAGAACATCTCCCGATCATGGAACTGGCTTTGATATTGCTGGCAAAGGAATA
GCACAATCTCAAAGTATGGTTGAAGCAATAAAAACAGCTATTGATTTAACAAAAGGTTCAAGACTGTTTAACGCGCATTA
A

Upstream 100 bases:

>100_bases
TTAAATAAATAATAATTTGATTTTATGACATTAATTAATAATCAAATCAAACGTTTTAGGAGAACATGAATCCTTTAATT
TTCCACATCAAAATTTTATT

Downstream 100 bases:

>100_bases
TACCTGTCCAAATTCTACTGGTGTTCCATTCTCAACAAGTATTTCTACGATTTCAGCATTAAACTCTGATTCAATTTCGT
TCATTAACTTCATAGCCTCA

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MSNKRNTIDDRLKVIISVGDDSGIGPEIILKALSSKEIPNNIDTLIVGSKINLKNTYKKLKSLGVQNIVDPSNYQIHDIE
IPFEINKPKQSNGNSSFFYLKKAIEIVQKYRNAALVTGPICKKSWALAGHNYSGQTELLAESCQVNNFGMLFTAKSPITN
WRFNTLLATTHIPLCEVPKQLSTKLIHSKLNLLATFCKNYVEKPILKIAGLNPHAGEEGILGSEEHDWINDAVNSWSEQN
KDVHLLGPISPDTCWNSSAKAWREDKAPTHNGILAMYHDQGLIPIKVIALNYSVNTTLGLPFIRTSPDHGTGFDIAGKGI
AQSQSMVEAIKTAIDLTKGSRLFNAH

Sequences:

>Translated_346_residues
MSNKRNTIDDRLKVIISVGDDSGIGPEIILKALSSKEIPNNIDTLIVGSKINLKNTYKKLKSLGVQNIVDPSNYQIHDIE
IPFEINKPKQSNGNSSFFYLKKAIEIVQKYRNAALVTGPICKKSWALAGHNYSGQTELLAESCQVNNFGMLFTAKSPITN
WRFNTLLATTHIPLCEVPKQLSTKLIHSKLNLLATFCKNYVEKPILKIAGLNPHAGEEGILGSEEHDWINDAVNSWSEQN
KDVHLLGPISPDTCWNSSAKAWREDKAPTHNGILAMYHDQGLIPIKVIALNYSVNTTLGLPFIRTSPDHGTGFDIAGKGI
AQSQSMVEAIKTAIDLTKGSRLFNAH
>Mature_345_residues
SNKRNTIDDRLKVIISVGDDSGIGPEIILKALSSKEIPNNIDTLIVGSKINLKNTYKKLKSLGVQNIVDPSNYQIHDIEI
PFEINKPKQSNGNSSFFYLKKAIEIVQKYRNAALVTGPICKKSWALAGHNYSGQTELLAESCQVNNFGMLFTAKSPITNW
RFNTLLATTHIPLCEVPKQLSTKLIHSKLNLLATFCKNYVEKPILKIAGLNPHAGEEGILGSEEHDWINDAVNSWSEQNK
DVHLLGPISPDTCWNSSAKAWREDKAPTHNGILAMYHDQGLIPIKVIALNYSVNTTLGLPFIRTSPDHGTGFDIAGKGIA
QSQSMVEAIKTAIDLTKGSRLFNAH

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=336, Percent_Identity=30.3571428571429, Blast_Score=144, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 38152; Mature: 38021

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKRNTIDDRLKVIISVGDDSGIGPEIILKALSSKEIPNNIDTLIVGSKINLKNTYKKL
CCCCCCCHHCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEECCEECHHHHHHHH
KSLGVQNIVDPSNYQIHDIEIPFEINKPKQSNGNSSFFYLKKAIEIVQKYRNAALVTGPI
HHCCHHHCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCC
CKKSWALAGHNYSGQTELLAESCQVNNFGMLFTAKSPITNWRFNTLLATTHIPLCEVPKQ
CCCCCEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEECCCCHHHCCHH
LSTKLIHSKLNLLATFCKNYVEKPILKIAGLNPHAGEEGILGSEEHDWINDAVNSWSEQN
HHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
KDVHLLGPISPDTCWNSSAKAWREDKAPTHNGILAMYHDQGLIPIKVIALNYSVNTTLGL
CCEEEECCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEEEEEECCEECC
PFIRTSPDHGTGFDIAGKGIAQSQSMVEAIKTAIDLTKGSRLFNAH
CEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCC
>Mature Secondary Structure 
SNKRNTIDDRLKVIISVGDDSGIGPEIILKALSSKEIPNNIDTLIVGSKINLKNTYKKL
CCCCCCHHCEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCEEEECCEECHHHHHHHH
KSLGVQNIVDPSNYQIHDIEIPFEINKPKQSNGNSSFFYLKKAIEIVQKYRNAALVTGPI
HHCCHHHCCCCCCCEEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCC
CKKSWALAGHNYSGQTELLAESCQVNNFGMLFTAKSPITNWRFNTLLATTHIPLCEVPKQ
CCCCCEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEECCCCHHHCCHH
LSTKLIHSKLNLLATFCKNYVEKPILKIAGLNPHAGEEGILGSEEHDWINDAVNSWSEQN
HHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
KDVHLLGPISPDTCWNSSAKAWREDKAPTHNGILAMYHDQGLIPIKVIALNYSVNTTLGL
CCEEEECCCCCCCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCEEEEEEEEEEECCEECC
PFIRTSPDHGTGFDIAGKGIAQSQSMVEAIKTAIDLTKGSRLFNAH
CEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA