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The map label for this gene is comM [H]

Identifier: 121999182

GI number: 121999182

Start: 2639705

End: 2641216

Strand: Reverse

Name: comM [H]

Synonym: Hhal_2404

Alternate gene names: 121999182

Gene position: 2641216-2639705 (Counterclockwise)

Preceding gene: 121999183

Following gene: 121999180

Centisome position: 98.61

GC content: 76.85

Gene sequence:

>1512_bases
ATGGCACTGGCGGTTACCCGGGCGCGGGCGGCGCTCGGTGTGGCGGCCCCCGAGGTCCAGGTGGAGGTCCACCTGGCGCC
GGGGCTGCCTGCGTTCTCACTGGTCGGCCTGCCCCAGGCCGAGGTGCGCGAGGCCCGGGACCGGGTCCGCAGCGCCATCA
TCAACAGCGGCCTGGAGTTTCCCGTCGGCCGCGTCACGGTCAACCTGGCCCCGGCGGATCTGCCCAAGGGCGGCGGACGC
TTCGATCTGGCCATCGCGGTCGGCGTGCTGGCGGCGTCGGGTCAGGCCCACGGCGAACTCGAATCGCTGGAGTTCATCGG
CGAGCTGGCCCTGGGCGGCCAGCTCCGCGAAGTGGGCGCCATCCTCCCGGCGGCACGGGCCGCCCGCGAGGCCGGCCGGC
GGCTGATCATCCCGGGCGGCGACGCCGCCGAGGCGGCATTGGTTCACCCCGGGGGCACGGTGGCCGCGCAGCGCCTGCTG
GCGGTGCTGGACCACCTGGACGGCCGCGAGCCCCTGCCCCCGGTGGGGTCGCCGACCGGGGCGCAGGAACGCTCTCCAGG
CCCCGATCTCGCCGACGTCCGCGGCCAGGCCGGCCCGCGCCGGGCGCTGGAGGTCGCCGCCGCGGGGGGGCACAACCTGC
TGCTCAGCGGCCCGCCCGGTACCGGCAAGAGCATGCTCGCCGAACGCCTGCCCGGGCTGTTGCCGCCGCTCCCGGAAGAC
GAGGCCCTGGAGGCGGCGGCGGTGCGCTCGGTCAGTGGCGAGGGGGTGGATCCGGCCAGCTGGCGGATCCCGGCCTTCCG
GGCCCCCCACCACAGCATCTCCCCGGCGGCGCTGATCGGTGGCGGGCAGCCGCCCCGCCCCGGCGAGGTCTCCCTGGCCC
ACCGCGGCGTGCTCTTCCTCGACGAGTTCCCCGAACTGCCCCGCAACGCCCTGGAGGCGCTGCGTGAGCCCCTGCAGGCG
CGGCGGGTGAGCATCGCCCGCAGCAACGCCCGGGTCACCTACCCGGCGGCCTTCCAGCTGGTGGCGGCCATGAACCCCTG
TCCCTGCGGCTACCACGGCGACCCCCGCGGCGAGTGCCGCTGCACCCCGGATCAGGTGGCGCGCTACCGCGACCGGATCA
CCGGGCCGCTGCTCGATCGCTTCGATATCGCCGTCGAGGTGCCGCGGCTCAGCGCCCGGGAGCTGACCGCCGCGCCGGCG
GCTGAGGCCACCGAGCAGGTGGCCGAACGGGTGGCCCGGGCCCGGGAGCGGCGGCGGGAGCGCTCCGGGCGGATCGCCGC
CGAGCTCAGCGGGGAGGTCCTGCACGCGGCCTGCCCCCTCGAGCCGGAGGCCGAGGCGACCCTGGAGCGGGCCACCGAGG
TCATCGGCCTCTCGCCGCGGGGGCACCACCGCCTGCTGCGGGTGGCGCGGACGATCGCCGATCTGGAAGGCATGGATGCC
ATCGACGCCCGCTACGTGGCCGAGGCGGTGGGGTTGCGCCGGGGGCTCGAGCAGCGGGGCGGGGTGGGGTGA

Upstream 100 bases:

>100_bases
GCTCGGGCGGCGCCGGCGGTAGCGGGAGCTGATCCGCAGGCGGGCCTGCGGGCTCGCCGCGTAGGTCGTCCTCTGTGCCC
ATGAACCAGGGAGGGTTCCC

Downstream 100 bases:

>100_bases
AAGGGGGGCGCCGGCGGCGCCCCCGGCTCAGGTTAGAAGGACCGTGAAACCATTACTGCGAACTGGTCGTCACTCCCAGA
TTCATCCGTATCTGTCCACA

Product: Mg chelatase subunit ChlI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MALAVTRARAALGVAAPEVQVEVHLAPGLPAFSLVGLPQAEVREARDRVRSAIINSGLEFPVGRVTVNLAPADLPKGGGR
FDLAIAVGVLAASGQAHGELESLEFIGELALGGQLREVGAILPAARAAREAGRRLIIPGGDAAEAALVHPGGTVAAQRLL
AVLDHLDGREPLPPVGSPTGAQERSPGPDLADVRGQAGPRRALEVAAAGGHNLLLSGPPGTGKSMLAERLPGLLPPLPED
EALEAAAVRSVSGEGVDPASWRIPAFRAPHHSISPAALIGGGQPPRPGEVSLAHRGVLFLDEFPELPRNALEALREPLQA
RRVSIARSNARVTYPAAFQLVAAMNPCPCGYHGDPRGECRCTPDQVARYRDRITGPLLDRFDIAVEVPRLSARELTAAPA
AEATEQVAERVARARERRRERSGRIAAELSGEVLHAACPLEPEAEATLERATEVIGLSPRGHHRLLRVARTIADLEGMDA
IDARYVAEAVGLRRGLEQRGGVG

Sequences:

>Translated_503_residues
MALAVTRARAALGVAAPEVQVEVHLAPGLPAFSLVGLPQAEVREARDRVRSAIINSGLEFPVGRVTVNLAPADLPKGGGR
FDLAIAVGVLAASGQAHGELESLEFIGELALGGQLREVGAILPAARAAREAGRRLIIPGGDAAEAALVHPGGTVAAQRLL
AVLDHLDGREPLPPVGSPTGAQERSPGPDLADVRGQAGPRRALEVAAAGGHNLLLSGPPGTGKSMLAERLPGLLPPLPED
EALEAAAVRSVSGEGVDPASWRIPAFRAPHHSISPAALIGGGQPPRPGEVSLAHRGVLFLDEFPELPRNALEALREPLQA
RRVSIARSNARVTYPAAFQLVAAMNPCPCGYHGDPRGECRCTPDQVARYRDRITGPLLDRFDIAVEVPRLSARELTAAPA
AEATEQVAERVARARERRRERSGRIAAELSGEVLHAACPLEPEAEATLERATEVIGLSPRGHHRLLRVARTIADLEGMDA
IDARYVAEAVGLRRGLEQRGGVG
>Mature_502_residues
ALAVTRARAALGVAAPEVQVEVHLAPGLPAFSLVGLPQAEVREARDRVRSAIINSGLEFPVGRVTVNLAPADLPKGGGRF
DLAIAVGVLAASGQAHGELESLEFIGELALGGQLREVGAILPAARAAREAGRRLIIPGGDAAEAALVHPGGTVAAQRLLA
VLDHLDGREPLPPVGSPTGAQERSPGPDLADVRGQAGPRRALEVAAAGGHNLLLSGPPGTGKSMLAERLPGLLPPLPEDE
ALEAAAVRSVSGEGVDPASWRIPAFRAPHHSISPAALIGGGQPPRPGEVSLAHRGVLFLDEFPELPRNALEALREPLQAR
RVSIARSNARVTYPAAFQLVAAMNPCPCGYHGDPRGECRCTPDQVARYRDRITGPLLDRFDIAVEVPRLSARELTAAPAA
EATEQVAERVARARERRRERSGRIAAELSGEVLHAACPLEPEAEATLERATEVIGLSPRGHHRLLRVARTIADLEGMDAI
DARYVAEAVGLRRGLEQRGGVG

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=501, Percent_Identity=49.500998003992, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 52724; Mature: 52593

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50051 MCM_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAVTRARAALGVAAPEVQVEVHLAPGLPAFSLVGLPQAEVREARDRVRSAIINSGLEF
CCEEHHHHHHHHCCCCCCEEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
PVGRVTVNLAPADLPKGGGRFDLAIAVGVLAASGQAHGELESLEFIGELALGGQLREVGA
CCCEEEEEECCCCCCCCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
ILPAARAAREAGRRLIIPGGDAAEAALVHPGGTVAAQRLLAVLDHLDGREPLPPVGSPTG
HHHHHHHHHHCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
AQERSPGPDLADVRGQAGPRRALEVAAAGGHNLLLSGPPGTGKSMLAERLPGLLPPLPED
CCCCCCCCCHHHHCCCCCCHHHHEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCC
EALEAAAVRSVSGEGVDPASWRIPAFRAPHHSISPAALIGGGQPPRPGEVSLAHRGVLFL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEHHHCCEEEE
DEFPELPRNALEALREPLQARRVSIARSNARVTYPAAFQLVAAMNPCPCGYHGDPRGECR
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCCCCCCCCCCCC
CTPDQVARYRDRITGPLLDRFDIAVEVPRLSARELTAAPAAEATEQVAERVARARERRRE
CCHHHHHHHHHHHCCHHHHHHHHEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RSGRIAAELSGEVLHAACPLEPEAEATLERATEVIGLSPRGHHRLLRVARTIADLEGMDA
HCCCEEEHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
IDARYVAEAVGLRRGLEQRGGVG
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ALAVTRARAALGVAAPEVQVEVHLAPGLPAFSLVGLPQAEVREARDRVRSAIINSGLEF
CEEHHHHHHHHCCCCCCEEEEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
PVGRVTVNLAPADLPKGGGRFDLAIAVGVLAASGQAHGELESLEFIGELALGGQLREVGA
CCCEEEEEECCCCCCCCCCCEEHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHH
ILPAARAAREAGRRLIIPGGDAAEAALVHPGGTVAAQRLLAVLDHLDGREPLPPVGSPTG
HHHHHHHHHHCCCEEEECCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
AQERSPGPDLADVRGQAGPRRALEVAAAGGHNLLLSGPPGTGKSMLAERLPGLLPPLPED
CCCCCCCCCHHHHCCCCCCHHHHEEEECCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCC
EALEAAAVRSVSGEGVDPASWRIPAFRAPHHSISPAALIGGGQPPRPGEVSLAHRGVLFL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEHHHCCEEEE
DEFPELPRNALEALREPLQARRVSIARSNARVTYPAAFQLVAAMNPCPCGYHGDPRGECR
HHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHCCCCCCCCCCCCCCCCC
CTPDQVARYRDRITGPLLDRFDIAVEVPRLSARELTAAPAAEATEQVAERVARARERRRE
CCHHHHHHHHHHHCCHHHHHHHHEEECCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RSGRIAAELSGEVLHAACPLEPEAEATLERATEVIGLSPRGHHRLLRVARTIADLEGMDA
HCCCEEEHHCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
IDARYVAEAVGLRRGLEQRGGVG
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]