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The map label for this gene is argB

Identifier: 121999074

GI number: 121999074

Start: 2523950

End: 2524852

Strand: Reverse

Name: argB

Synonym: Hhal_2296

Alternate gene names: 121999074

Gene position: 2524852-2523950 (Counterclockwise)

Preceding gene: 121999075

Following gene: 121999062

Centisome position: 94.27

GC content: 66.45

Gene sequence:

>903_bases
ATGCCCGAGACCCCAATTGATCCCGATCTTACCGCCCAGGTCCTGGTCGAGGCGCTGCCGTACATCCGGCGCTTCCGTGG
CAAGACCATTGTCGTCAAATTCGGCGGTAACGCCATGGTGGACGAGGCACTGAAGGTGGCCTTCGCGCGGGATATCGTGC
TCATGCGGCTGGTCGGTTTCCGGGTTGTGGTGGTCCACGGCGGTGGCCCGCAGATCGGTAACCTGCTCGAGCGCATCGGC
AAGGAGACGGAGTTCGTCCAGGGCATGCGGGTGACGGACGCCGAGACCATGGACGTGGTGGAGATGGTGCTCGGTGGCCT
GGTCAACAAGGAGATCGTCAACCTGATCAGCGCCCAGGGCGGTCGCGCCGTGGGGCTCACTGGCAAGGACGGCGGCCTGA
TCCGGGCCCGCAAGCTGGAGGTGGAGCAGCCCGGGCCTGAGAACCAGGTCCCGGAGATTATCGATATCGGCCACGTCGGC
GAGGTCGATCACATCGACCCGGCGGTGGTCGAGATGCTCGACTCCGGCGAGTTCATCCCGGTGGTTGCGCCCATCGGCGT
GGACGAGCGTGGCACCTCCTACAACATCAATGCCGATCTGGTGGCCGGCAAGATCGCCGAGGTGCTCAGCGCGGAGAAGC
TGTTGCTGCTCACCAACACGCCGGGGGTGCTCGACGGCGCCGGTCATCTGCTCACCGGCCTGAGTCCCGAGCGGGTCGAT
GAGCTGATCGCCGACGGCACCATCGCCGGCGGCATGCTGCCGAAGATCCGCTGCGCTCTGGACGCCGTCGCCGGCGGCGT
GCGCAATGCGCACATCATCGATGGCCGGGTGCCCCATGCGGTGCTGCTCGAGCTCTTCACCGACAAGGGCGTGGGGACGC
TGATCCGGCGTCAGCCGGAGTAG

Upstream 100 bases:

>100_bases
GGCGCCTTGTCAGGAGCCGTTCGGCCCTGGAAACTCCCAGCGCGAAACCAGATAACGATACCCAGCCTCCAAACCCGAAT
CTCAGAATACGATCCGAGCC

Downstream 100 bases:

>100_bases
GTGCCCCGTTCAGCGCGTGGGGCGGACCGCAGCCCCCAGATCCAGTACCCGGCCAGGCCGAGCATGGCCGCCAGGGAGGC
CACGTAGGCCTCCCAGCCCA

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MPETPIDPDLTAQVLVEALPYIRRFRGKTIVVKFGGNAMVDEALKVAFARDIVLMRLVGFRVVVVHGGGPQIGNLLERIG
KETEFVQGMRVTDAETMDVVEMVLGGLVNKEIVNLISAQGGRAVGLTGKDGGLIRARKLEVEQPGPENQVPEIIDIGHVG
EVDHIDPAVVEMLDSGEFIPVVAPIGVDERGTSYNINADLVAGKIAEVLSAEKLLLLTNTPGVLDGAGHLLTGLSPERVD
ELIADGTIAGGMLPKIRCALDAVAGGVRNAHIIDGRVPHAVLLELFTDKGVGTLIRRQPE

Sequences:

>Translated_300_residues
MPETPIDPDLTAQVLVEALPYIRRFRGKTIVVKFGGNAMVDEALKVAFARDIVLMRLVGFRVVVVHGGGPQIGNLLERIG
KETEFVQGMRVTDAETMDVVEMVLGGLVNKEIVNLISAQGGRAVGLTGKDGGLIRARKLEVEQPGPENQVPEIIDIGHVG
EVDHIDPAVVEMLDSGEFIPVVAPIGVDERGTSYNINADLVAGKIAEVLSAEKLLLLTNTPGVLDGAGHLLTGLSPERVD
ELIADGTIAGGMLPKIRCALDAVAGGVRNAHIIDGRVPHAVLLELFTDKGVGTLIRRQPE
>Mature_299_residues
PETPIDPDLTAQVLVEALPYIRRFRGKTIVVKFGGNAMVDEALKVAFARDIVLMRLVGFRVVVVHGGGPQIGNLLERIGK
ETEFVQGMRVTDAETMDVVEMVLGGLVNKEIVNLISAQGGRAVGLTGKDGGLIRARKLEVEQPGPENQVPEIIDIGHVGE
VDHIDPAVVEMLDSGEFIPVVAPIGVDERGTSYNINADLVAGKIAEVLSAEKLLLLTNTPGVLDGAGHLLTGLSPERVDE
LIADGTIAGGMLPKIRCALDAVAGGVRNAHIIDGRVPHAVLLELFTDKGVGTLIRRQPE

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=286, Percent_Identity=31.4685314685315, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI145693208, Length=274, Percent_Identity=31.3868613138686, Blast_Score=96, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320913, Length=287, Percent_Identity=26.4808362369338, Blast_Score=82, Evalue=8e-17,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_HALHL (A1WZE7)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003861.1
- ProteinModelPortal:   A1WZE7
- SMR:   A1WZE7
- STRING:   A1WZE7
- GeneID:   4709111
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2296
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   A1WZE7
- ProtClustDB:   PRK00942
- BioCyc:   HHAL349124:HHAL_2296-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31865; Mature: 31733

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: BINDING 90-90 BINDING 195-195

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPETPIDPDLTAQVLVEALPYIRRFRGKTIVVKFGGNAMVDEALKVAFARDIVLMRLVGF
CCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCE
RVVVVHGGGPQIGNLLERIGKETEFVQGMRVTDAETMDVVEMVLGGLVNKEIVNLISAQG
EEEEEECCCCCHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
GRAVGLTGKDGGLIRARKLEVEQPGPENQVPEIIDIGHVGEVDHIDPAVVEMLDSGEFIP
CEEEEECCCCCCEEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCEEE
VVAPIGVDERGTSYNINADLVAGKIAEVLSAEKLLLLTNTPGVLDGAGHLLTGLSPERVD
EEECCCCCCCCCEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHCCCCHHHHH
ELIADGTIAGGMLPKIRCALDAVAGGVRNAHIIDGRVPHAVLLELFTDKGVGTLIRRQPE
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHCCCCC
>Mature Secondary Structure 
PETPIDPDLTAQVLVEALPYIRRFRGKTIVVKFGGNAMVDEALKVAFARDIVLMRLVGF
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCE
RVVVVHGGGPQIGNLLERIGKETEFVQGMRVTDAETMDVVEMVLGGLVNKEIVNLISAQG
EEEEEECCCCCHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
GRAVGLTGKDGGLIRARKLEVEQPGPENQVPEIIDIGHVGEVDHIDPAVVEMLDSGEFIP
CEEEEECCCCCCEEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCCEEE
VVAPIGVDERGTSYNINADLVAGKIAEVLSAEKLLLLTNTPGVLDGAGHLLTGLSPERVD
EEECCCCCCCCCEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHCCCCHHHHH
ELIADGTIAGGMLPKIRCALDAVAGGVRNAHIIDGRVPHAVLLELFTDKGVGTLIRRQPE
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHHCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA