Click here to switch to the map view.

The map label for this gene is qorA [H]

Identifier: 121998973

GI number: 121998973

Start: 2405783

End: 2406772

Strand: Reverse

Name: qorA [H]

Synonym: Hhal_2194

Alternate gene names: 121998973

Gene position: 2406772-2405783 (Counterclockwise)

Preceding gene: 121998974

Following gene: 121998969

Centisome position: 89.86

GC content: 71.31

Gene sequence:

>990_bases
ATGGCCCGCGCTGTCCGCATCCATCAAACGGGTGGCCCCGAGCAACTCCAGGTCGAGGAGATCGACGTGCCCGCCCCCGG
TCCGGGTGAGGTCCTGTTGCGCCAGACCGCCTGCGGGGTCAACTTCATCGACTGCTACCACCGCAGCGGGTTGTACCCGC
TGCCCCAGCTGCCCCACGGCATCGGGGTCGAGGCCTGTGGTGTGGTCGAGGCGGTCGGCGACGGGGTCCGCGGGGTGCAG
ACCGGGGAACGGATGGCGTATGCCACGCCGCCACCCGGCGCCTACGCCGAGGCCCGCGTGCTGCCGGCGGATCGCCTGAT
CCCGGTCCCCGACGAGGTGGAGGACGCGGTGGCCGGTGGCACGACTCTCCGCGGCCTCACGGCGTGGCTGCTGCTGCACC
GTACCTTCCCGGTGCGCCGGGGGCATACGCTGCTGATCCACGCCGCCGCGGGCGGGGTGGGGCAGATCCTCTGTCAGTGG
GCGGACTACCTCGGGGCCACGGTGATCGGCACCGTGGGCGACGAGGACAAGGCGCAGGTGGCCGCCGAGCACGGCTGTCA
CCACCCCATCCTCTACACCCAAGACGACTTCCGCGAGAAGGTCGAGGCGATCACCGGGGGACGCGGTGTGGATGTGGTCT
ACGACTCGGTGGGGGCGGCCACCTTCGAGGCCTCGCTGGATTGCCTGCGCCCACTGGGGATGATGGTCAGTTACGGCAAT
GCCTCGGGGGCTCCGCCTGCCATCGAGCCCGGGCTGCTGGCGCAGAAGGGGTCGCTGTTCCTGACCCGGCCGGTGCTGTT
CCACTACATCGCCGATCGGCACGAGCTGCTGGCCGGAGCGTCGGCCTACTACGATGCCCTTACGCAGGGGGTGATCGAGC
CGGCGGTGGGGCGGCGCTACCCGCTGGAGAAGGCGGCCCGGGCCCACACGGATCTGGAGGCGCGGGCGACCACCGGCGCC
ACGGTGCTCGATCTCGGCGCAGCGGATTGA

Upstream 100 bases:

>100_bases
CGGACTCGAACATCCGGAACTCGGCCCGGCCTTCCGGGACTATCTCAAAGGGCTGGACACCGGCGCCTGAGCGGCGCCGC
CCGGCCAACAGGAGGACGCC

Downstream 100 bases:

>100_bases
CCCCGGCGCGGGGGATGCCCCCGGTCCGCCGGCGTCATTGAGCGCGCCGAGCCGCGCAGCCGGCGCGGGGGCCCAGCGCG
AACCTTGACCGGTTCGCGCT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MARAVRIHQTGGPEQLQVEEIDVPAPGPGEVLLRQTACGVNFIDCYHRSGLYPLPQLPHGIGVEACGVVEAVGDGVRGVQ
TGERMAYATPPPGAYAEARVLPADRLIPVPDEVEDAVAGGTTLRGLTAWLLLHRTFPVRRGHTLLIHAAAGGVGQILCQW
ADYLGATVIGTVGDEDKAQVAAEHGCHHPILYTQDDFREKVEAITGGRGVDVVYDSVGAATFEASLDCLRPLGMMVSYGN
ASGAPPAIEPGLLAQKGSLFLTRPVLFHYIADRHELLAGASAYYDALTQGVIEPAVGRRYPLEKAARAHTDLEARATTGA
TVLDLGAAD

Sequences:

>Translated_329_residues
MARAVRIHQTGGPEQLQVEEIDVPAPGPGEVLLRQTACGVNFIDCYHRSGLYPLPQLPHGIGVEACGVVEAVGDGVRGVQ
TGERMAYATPPPGAYAEARVLPADRLIPVPDEVEDAVAGGTTLRGLTAWLLLHRTFPVRRGHTLLIHAAAGGVGQILCQW
ADYLGATVIGTVGDEDKAQVAAEHGCHHPILYTQDDFREKVEAITGGRGVDVVYDSVGAATFEASLDCLRPLGMMVSYGN
ASGAPPAIEPGLLAQKGSLFLTRPVLFHYIADRHELLAGASAYYDALTQGVIEPAVGRRYPLEKAARAHTDLEARATTGA
TVLDLGAAD
>Mature_328_residues
ARAVRIHQTGGPEQLQVEEIDVPAPGPGEVLLRQTACGVNFIDCYHRSGLYPLPQLPHGIGVEACGVVEAVGDGVRGVQT
GERMAYATPPPGAYAEARVLPADRLIPVPDEVEDAVAGGTTLRGLTAWLLLHRTFPVRRGHTLLIHAAAGGVGQILCQWA
DYLGATVIGTVGDEDKAQVAAEHGCHHPILYTQDDFREKVEAITGGRGVDVVYDSVGAATFEASLDCLRPLGMMVSYGNA
SGAPPAIEPGLLAQKGSLFLTRPVLFHYIADRHELLAGASAYYDALTQGVIEPAVGRRYPLEKAARAHTDLEARATTGAT
VLDLGAAD

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=29.7872340425532, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=29.7872340425532, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI22538446, Length=332, Percent_Identity=31.9277108433735, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI22538444, Length=332, Percent_Identity=31.9277108433735, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI194239676, Length=328, Percent_Identity=28.6585365853659, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI18379349, Length=311, Percent_Identity=31.5112540192926, Blast_Score=124, Evalue=9e-29,
Organism=Homo sapiens, GI24308257, Length=346, Percent_Identity=28.0346820809249, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI28557745, Length=319, Percent_Identity=31.3479623824451, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI197927207, Length=190, Percent_Identity=27.3684210526316, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1790485, Length=325, Percent_Identity=45.8461538461538, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI226510941, Length=256, Percent_Identity=29.296875, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=314, Percent_Identity=26.1146496815287, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319520, Length=327, Percent_Identity=33.3333333333333, Blast_Score=178, Evalue=1e-45,
Organism=Drosophila melanogaster, GI45550423, Length=265, Percent_Identity=26.0377358490566, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34720; Mature: 34589

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARAVRIHQTGGPEQLQVEEIDVPAPGPGEVLLRQTACGVNFIDCYHRSGLYPLPQLPHG
CCCEEEEECCCCCCEEEEEEECCCCCCCHHHHEEHHHCCCHHHHHHHCCCCCCCCCCCCC
IGVEACGVVEAVGDGVRGVQTGERMAYATPPPGAYAEARVLPADRLIPVPDEVEDAVAGG
CCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHCCC
TTLRGLTAWLLLHRTFPVRRGHTLLIHAAAGGVGQILCQWADYLGATVIGTVGDEDKAQV
CHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCHHHHH
AAEHGCHHPILYTQDDFREKVEAITGGRGVDVVYDSVGAATFEASLDCLRPLGMMVSYGN
HHHCCCCCCEEECCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHEEECCC
ASGAPPAIEPGLLAQKGSLFLTRPVLFHYIADRHELLAGASAYYDALTQGVIEPAVGRRY
CCCCCCCCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLEKAARAHTDLEARATTGATVLDLGAAD
CHHHHHHHHCCCHHHCCCCCEEEECCCCC
>Mature Secondary Structure 
ARAVRIHQTGGPEQLQVEEIDVPAPGPGEVLLRQTACGVNFIDCYHRSGLYPLPQLPHG
CCEEEEECCCCCCEEEEEEECCCCCCCHHHHEEHHHCCCHHHHHHHCCCCCCCCCCCCC
IGVEACGVVEAVGDGVRGVQTGERMAYATPPPGAYAEARVLPADRLIPVPDEVEDAVAGG
CCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCHHHHHHCCC
TTLRGLTAWLLLHRTFPVRRGHTLLIHAAAGGVGQILCQWADYLGATVIGTVGDEDKAQV
CHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEECCCCCHHHHH
AAEHGCHHPILYTQDDFREKVEAITGGRGVDVVYDSVGAATFEASLDCLRPLGMMVSYGN
HHHCCCCCCEEECCHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHEEECCC
ASGAPPAIEPGLLAQKGSLFLTRPVLFHYIADRHELLAGASAYYDALTQGVIEPAVGRRY
CCCCCCCCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PLEKAARAHTDLEARATTGATVLDLGAAD
CHHHHHHHHCCCHHHCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]