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The map label for this gene is nadD

Identifier: 121998920

GI number: 121998920

Start: 2341767

End: 2342423

Strand: Reverse

Name: nadD

Synonym: Hhal_2141

Alternate gene names: 121998920

Gene position: 2342423-2341767 (Counterclockwise)

Preceding gene: 121998921

Following gene: 121998919

Centisome position: 87.45

GC content: 72.3

Gene sequence:

>657_bases
GTGAGACAACCGCTGCGTACTATTGGCCTGCTCGGTGGCACGTTCGATCCCATCCACTACGGCCACCTGCGCCCGGCCGA
GGAGGTCCGCGAGGCCGTGCAGCTCTCCGAGCTGCGCCTGATCCCGGCGCGCATCCCGCCCCACCGGGCCCGTCCGCGGG
TCGGGCCCGAGCAGCGCGCCGAACTGGTGCGCCGGGCCGTGGCCGACAACCCCAGCGCCTGCGTCGATGAGCGGGAGCTG
CACCGCGATGGGCCCTCCTACACCGTCGACACCCTGGCCGAGCTTCGCGCCGAGCTCGGTGGTGTCTCGCTGTGCCTGAT
CCTCGGGTACGACACTTTTCTCGGGCTGCCTGGCTGGTCCCGCTGGCGGCAGCTGTTCGAACGGGCCCACGTGGTGGTCA
CCGAGCGGCCCGGGGTGCGAGGCGCGCTGCCCGAGGCGCTGGCCACCGAGGTGGCCAGGCGGGTTGCGCACGAGCCGGCC
GAGCTGCGCCATCGTCCGGCCGGTTGCATCCTGTTTCAGGCGGTGACACCGGTGGATATCTCCGCTACGGGGATCCGCCG
CTCCCTGGCGCTGGGCCGGTCCGTGCGCTATCTGCTGCCCGAGGCGGTGCGGCAGCGGGTGGTCGAGGCGGGCTGGTACG
GCTACCCGCAGTTGTAA

Upstream 100 bases:

>100_bases
CACGCCCGGGGCCCGGTGGGGCTGGAGGGGCTGACCACCGAGAAGTGGATCGTCCTCGGTGACGGTCACGTCCGCAGCTG
ACGGCGAGGTGAGCGGACGC

Downstream 100 bases:

>100_bases
GAGGTCGTCATGGTGGTGGAAGAGCTGGAGCAACGGATCCGCGAGTCCCTGGACGCGATCAAGGCCCAGGATACGGTGGC
CATCGATGTCCGCGGGCGTA

Product: nicotinate (nicotinamide) nucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MRQPLRTIGLLGGTFDPIHYGHLRPAEEVREAVQLSELRLIPARIPPHRARPRVGPEQRAELVRRAVADNPSACVDEREL
HRDGPSYTVDTLAELRAELGGVSLCLILGYDTFLGLPGWSRWRQLFERAHVVVTERPGVRGALPEALATEVARRVAHEPA
ELRHRPAGCILFQAVTPVDISATGIRRSLALGRSVRYLLPEAVRQRVVEAGWYGYPQL

Sequences:

>Translated_218_residues
MRQPLRTIGLLGGTFDPIHYGHLRPAEEVREAVQLSELRLIPARIPPHRARPRVGPEQRAELVRRAVADNPSACVDEREL
HRDGPSYTVDTLAELRAELGGVSLCLILGYDTFLGLPGWSRWRQLFERAHVVVTERPGVRGALPEALATEVARRVAHEPA
ELRHRPAGCILFQAVTPVDISATGIRRSLALGRSVRYLLPEAVRQRVVEAGWYGYPQL
>Mature_218_residues
MRQPLRTIGLLGGTFDPIHYGHLRPAEEVREAVQLSELRLIPARIPPHRARPRVGPEQRAELVRRAVADNPSACVDEREL
HRDGPSYTVDTLAELRAELGGVSLCLILGYDTFLGLPGWSRWRQLFERAHVVVTERPGVRGALPEALATEVARRVAHEPA
ELRHRPAGCILFQAVTPVDISATGIRRSLALGRSVRYLLPEAVRQRVVEAGWYGYPQL

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=207, Percent_Identity=39.1304347826087, Blast_Score=156, Evalue=8e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_HALHL (A1WYZ3)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003707.1
- ProteinModelPortal:   A1WYZ3
- SMR:   A1WYZ3
- STRING:   A1WYZ3
- GeneID:   4711338
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2141
- eggNOG:   COG1057
- HOGENOM:   HBG739448
- OMA:   LLGWDAF
- PhylomeDB:   A1WYZ3
- ProtClustDB:   CLSK727108
- BioCyc:   HHAL349124:HHAL_2141-MONOMER
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.18

Molecular weight: Translated: 24331; Mature: 24331

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQPLRTIGLLGGTFDPIHYGHLRPAEEVREAVQLSELRLIPARIPPHRARPRVGPEQRA
CCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
ELVRRAVADNPSACVDERELHRDGPSYTVDTLAELRAELGGVSLCLILGYDTFLGLPGWS
HHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHCCCCHH
RWRQLFERAHVVVTERPGVRGALPEALATEVARRVAHEPAELRHRPAGCILFQAVTPVDI
HHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCCCC
SATGIRRSLALGRSVRYLLPEAVRQRVVEAGWYGYPQL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRQPLRTIGLLGGTFDPIHYGHLRPAEEVREAVQLSELRLIPARIPPHRARPRVGPEQRA
CCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHH
ELVRRAVADNPSACVDERELHRDGPSYTVDTLAELRAELGGVSLCLILGYDTFLGLPGWS
HHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHCCHHHHHCCCCHH
RWRQLFERAHVVVTERPGVRGALPEALATEVARRVAHEPAELRHRPAGCILFQAVTPVDI
HHHHHHHHHCEEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCCCC
SATGIRRSLALGRSVRYLLPEAVRQRVVEAGWYGYPQL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA