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The map label for this gene is tldD [H]

Identifier: 121998913

GI number: 121998913

Start: 2333143

End: 2334615

Strand: Reverse

Name: tldD [H]

Synonym: Hhal_2134

Alternate gene names: 121998913

Gene position: 2334615-2333143 (Counterclockwise)

Preceding gene: 121998914

Following gene: 121998912

Centisome position: 87.16

GC content: 71.08

Gene sequence:

>1473_bases
ATGAAGAATCACGCCGAAGCCGCTACTGCGACCCGGGACCCGCTCCACCACGCCGAGGCGCAGCTGCTGGCGCCGGCCGC
CCTCGATGAGGCCCGGCTCGGTCAGGTGTTCAGCCGGCTGCTGCGCCCGGGGGTGGACTTCGCCGATCTGTACTTCCAGG
CCGCTCGACGTGAGGCGTGGGTGCTGGAGGACGGCATCGTCCGCGAGGGCAGCTACAGTATCGATCGCGGCGTCGGGGTG
CGTGCCGTCAGCGGCGAGAAGACCGGTTTCGCCTACTGCGACGAGATCGGCCTGGAGGCGTTGCTCGATGCCTCCTCGGC
GGCCGGCGCGGTGGCGCGCAGCGGGCAGAGCCGCAGCCTGGCCGCCTTCCGTGCGGGGGGCGGGCGTGGCCTCTACCGGG
GCGATGATCCGCTGGCGAGTCTGAGCGCCGACGACAAGGTCGCCCTGCTGCACCGCGCCGAGGCGGCGGCGCGCGCCGTC
GACCCGCGCATCGTGCATGTGGTGGCGAGCCTGGCCGGCGCTCACGACACCATCCTGGTGGCCAACTCGGAGGGTGGCTG
GGCCGGCGATATCCGCCCTCTGGTTCGGCTCAATGTCTCGGTGCTGGCCGCTTCCGGCGAGCGCCGCGAGAGCGGCAGCT
CCGGCGGCGGCGGGCGCTACGACTACCAGCAGTTCGTCGAGCCGGAGCGTGTCGAGGCCTACGCCCGTGAGGCGGCCCGG
CAGGCGCTGGTCAACCTCGAGGCCGAGGAGGCACCGGCGGGGCATCTGCCCGTGGTCCTCGGCCCCGGATGGCCCGGTGT
GCTCCTGCACGAGGCCGTCGGTCACGGCCTGGAGGGCGACTTCAACCGCAAGGGCACCTCGGCGTTCAGCGGGCGCATCG
GTGAGCGTGTGGCGTCGCCCCTGTGTACCGTGGTCGATGACGGCACCATCGCCCAGCGGCGCGGCTCGCTGAACATCGAC
GATGAGGGCCATCCGAGCCAGTGCAATACCCTCATCGAGGACGGGGTGCTGACCGGCTACATGCAGGATCGGCAGAACGC
CGGTCTGATGGGCATGGCCCGGACCGGCAACGCCCGGCGGGAGTCCTACGCGCACCTGCCCATGCCGCGGATGACCAACA
CCTACATGCTCGCCGGCCCCCACGACCCCGAGGAGATCATCGCCTCCGTGGATCAGGGGCTGTACGCGGTGAACTTCGGC
GGCGGCCAGGTGGATATCACCTCGGGCAAGTTCGTCTTCTCGGCCAGCGAGGCCTACTGGATCGAGAACGGGCGCATCCA
GCACCCGGTCAAGGGCGCGACACTGATCGGCAACGGCCCGGACGTGCTGACGCGGGTGAGCATGGTGGGCAACGACCTGG
CGCTCGACGGCGGCATCGGGGTCTGCGGCAAGGAGGGGCAGAGCGTCCCCGTGGGGGTCGGTCAGCCGACGCTCAAGGTC
GACGGCATGACCGTCGGTGGCACGCAGGCCTAG

Upstream 100 bases:

>100_bases
GCGGCGCCGGGGTGATCACCGTGGAGGTGAGCCTGAGCCGCCTGCACGAGATCCGGGAGCGTTTCCCGGCACTCCTTCAC
CGCAAGCTGTAGGTGACCGC

Downstream 100 bases:

>100_bases
CCGCACCGCGCCGCTGCCTGGAAACCCAACTCACAACGGAAAAGGCGAACCCATGCCGGATCCACGCAACGAGCTACCTG
CCCCGGGAACGCTGGAGGAC

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MKNHAEAATATRDPLHHAEAQLLAPAALDEARLGQVFSRLLRPGVDFADLYFQAARREAWVLEDGIVREGSYSIDRGVGV
RAVSGEKTGFAYCDEIGLEALLDASSAAGAVARSGQSRSLAAFRAGGGRGLYRGDDPLASLSADDKVALLHRAEAAARAV
DPRIVHVVASLAGAHDTILVANSEGGWAGDIRPLVRLNVSVLAASGERRESGSSGGGGRYDYQQFVEPERVEAYAREAAR
QALVNLEAEEAPAGHLPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGERVASPLCTVVDDGTIAQRRGSLNID
DEGHPSQCNTLIEDGVLTGYMQDRQNAGLMGMARTGNARRESYAHLPMPRMTNTYMLAGPHDPEEIIASVDQGLYAVNFG
GGQVDITSGKFVFSASEAYWIENGRIQHPVKGATLIGNGPDVLTRVSMVGNDLALDGGIGVCGKEGQSVPVGVGQPTLKV
DGMTVGGTQA

Sequences:

>Translated_490_residues
MKNHAEAATATRDPLHHAEAQLLAPAALDEARLGQVFSRLLRPGVDFADLYFQAARREAWVLEDGIVREGSYSIDRGVGV
RAVSGEKTGFAYCDEIGLEALLDASSAAGAVARSGQSRSLAAFRAGGGRGLYRGDDPLASLSADDKVALLHRAEAAARAV
DPRIVHVVASLAGAHDTILVANSEGGWAGDIRPLVRLNVSVLAASGERRESGSSGGGGRYDYQQFVEPERVEAYAREAAR
QALVNLEAEEAPAGHLPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGERVASPLCTVVDDGTIAQRRGSLNID
DEGHPSQCNTLIEDGVLTGYMQDRQNAGLMGMARTGNARRESYAHLPMPRMTNTYMLAGPHDPEEIIASVDQGLYAVNFG
GGQVDITSGKFVFSASEAYWIENGRIQHPVKGATLIGNGPDVLTRVSMVGNDLALDGGIGVCGKEGQSVPVGVGQPTLKV
DGMTVGGTQA
>Mature_490_residues
MKNHAEAATATRDPLHHAEAQLLAPAALDEARLGQVFSRLLRPGVDFADLYFQAARREAWVLEDGIVREGSYSIDRGVGV
RAVSGEKTGFAYCDEIGLEALLDASSAAGAVARSGQSRSLAAFRAGGGRGLYRGDDPLASLSADDKVALLHRAEAAARAV
DPRIVHVVASLAGAHDTILVANSEGGWAGDIRPLVRLNVSVLAASGERRESGSSGGGGRYDYQQFVEPERVEAYAREAAR
QALVNLEAEEAPAGHLPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGERVASPLCTVVDDGTIAQRRGSLNID
DEGHPSQCNTLIEDGVLTGYMQDRQNAGLMGMARTGNARRESYAHLPMPRMTNTYMLAGPHDPEEIIASVDQGLYAVNFG
GGQVDITSGKFVFSASEAYWIENGRIQHPVKGATLIGNGPDVLTRVSMVGNDLALDGGIGVCGKEGQSVPVGVGQPTLKV
DGMTVGGTQA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=478, Percent_Identity=60.6694560669456, Blast_Score=556, Evalue=1e-159,
Organism=Escherichia coli, GI1790682, Length=329, Percent_Identity=26.1398176291793, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51434; Mature: 51434

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNHAEAATATRDPLHHAEAQLLAPAALDEARLGQVFSRLLRPGVDFADLYFQAARREAW
CCCCHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEE
VLEDGIVREGSYSIDRGVGVRAVSGEKTGFAYCDEIGLEALLDASSAAGAVARSGQSRSL
EECCCCEECCCCCCCCCCCEEEECCCCCCCHHHHHHCHHHHHCCCHHHHHHHHCCCCCCE
AAFRAGGGRGLYRGDDPLASLSADDKVALLHRAEAAARAVDPRIVHVVASLAGAHDTILV
EEEECCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEE
ANSEGGWAGDIRPLVRLNVSVLAASGERRESGSSGGGGRYDYQQFVEPERVEAYAREAAR
ECCCCCCCCCCCHHHEEEEEEEEECCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHH
QALVNLEAEEAPAGHLPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGERVASP
HHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC
LCTVVDDGTIAQRRGSLNIDDEGHPSQCNTLIEDGVLTGYMQDRQNAGLMGMARTGNARR
CEEEECCCCHHHHCCCCCCCCCCCCHHHHHHHHCCEEEEHHHHCCCCCEEEEECCCCCHH
ESYAHLPMPRMTNTYMLAGPHDPEEIIASVDQGLYAVNFGGGQVDITSGKFVFSASEAYW
HCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCCEEEEECCEEEEECCCEEE
IENGRIQHPVKGATLIGNGPDVLTRVSMVGNDLALDGGIGVCGKEGQSVPVGVGQPTLKV
EECCEEECCCCCCEEECCCHHHHHHHHHHCCCEEECCCCEEECCCCCCCCCCCCCCEEEE
DGMTVGGTQA
CCEECCCCCC
>Mature Secondary Structure
MKNHAEAATATRDPLHHAEAQLLAPAALDEARLGQVFSRLLRPGVDFADLYFQAARREAW
CCCCHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCEE
VLEDGIVREGSYSIDRGVGVRAVSGEKTGFAYCDEIGLEALLDASSAAGAVARSGQSRSL
EECCCCEECCCCCCCCCCCEEEECCCCCCCHHHHHHCHHHHHCCCHHHHHHHHCCCCCCE
AAFRAGGGRGLYRGDDPLASLSADDKVALLHRAEAAARAVDPRIVHVVASLAGAHDTILV
EEEECCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEE
ANSEGGWAGDIRPLVRLNVSVLAASGERRESGSSGGGGRYDYQQFVEPERVEAYAREAAR
ECCCCCCCCCCCHHHEEEEEEEEECCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHH
QALVNLEAEEAPAGHLPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSAFSGRIGERVASP
HHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC
LCTVVDDGTIAQRRGSLNIDDEGHPSQCNTLIEDGVLTGYMQDRQNAGLMGMARTGNARR
CEEEECCCCHHHHCCCCCCCCCCCCHHHHHHHHCCEEEEHHHHCCCCCEEEEECCCCCHH
ESYAHLPMPRMTNTYMLAGPHDPEEIIASVDQGLYAVNFGGGQVDITSGKFVFSASEAYW
HCCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCEEEEEECCCEEEEECCEEEEECCCEEE
IENGRIQHPVKGATLIGNGPDVLTRVSMVGNDLALDGGIGVCGKEGQSVPVGVGQPTLKV
EECCEEECCCCCCEEECCCHHHHHHHHHHCCCEEECCCCEEECCCCCCCCCCCCCCEEEE
DGMTVGGTQA
CCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]