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The map label for this gene is murA

Identifier: 121998893

GI number: 121998893

Start: 2319187

End: 2320443

Strand: Reverse

Name: murA

Synonym: Hhal_2114

Alternate gene names: 121998893

Gene position: 2320443-2319187 (Counterclockwise)

Preceding gene: 121998894

Following gene: 121998892

Centisome position: 86.63

GC content: 69.45

Gene sequence:

>1257_bases
ATGGAGCGACTGCTCATCCGGGGCGGTAACCCCCTGCGTGGCGATATCCGTATCTCCGGGGCCAAGAATGCGGCCCTGCC
GGTCATGGCGGCGACCCTGCTGGCCGACGGCCCGACCACCGTCGGCAACATCCCGCATCTCCACGACGTAACCACCACCA
TGGAGCTGCTCGGGCGCATGGGGGTGGAGCTCACCGTGCACGAGGGTATGGAGGTCGAGGTCAACACCGCGACCATCCAC
AGCTTCCGGGCGCCCTACGAATTGGTGAAGACCATGCGCGCCTCGATCCTGGTGCTCGGGCCGCTGCTGGCGCGCTTCGG
CCAGGCCGAGGTGTCGCTGCCCGGGGGCTGCGCCATCGGCTCGCGGCCGGTCAACATCCACGTGGACGGGTTGCGGGCCA
TGGGCGCCGAGATCGAGGTCCGCGACGGGTACATCAAGGGCCGCGCCGACCGGCTCCAGGGGGCGCACATCCGCATGGAT
GTCTCGACGGTGACCGGAACCGAAAACCTGATGATGGCGGCCGCCCTGGCGCGCGGAACCACGGTACTCGAGAATGCCGC
CCGCGAGCCCGAGGTCATCAATCTGGCCGACTGCATCAACGCCATGGGGGGGCACGTCCAGGGGGCCGGCACCTCGACGA
TCACCATCGAGGGGGTCGACACGCTGCGCGGCGTTCACCATCGAGTGCTGCCCGATCGCATTGAGACCGGCACCTACCTG
GTCGCTGCGGCCATGACCGGGGGAGAGGTGCGGCTCAAGGACACGGCGCCGGAGCTGGTCGAGTCGGTGCTCGGCAAGCT
GCGCGAGAGCGGGGCAGAGGTGAGCGCCGGTCGCGACTGGGTGACCCTGCGCATGGAGGGCCGCCCGCGCGCCGTGGACC
TGGAGACGGCGCCGTACCCGGGCTTCCCCACGGACATGCAGGCCCAGTTCTGTGCCCTGAACGCCATCTCCACCGGGGAG
GGGACGGTGACCGAGACCGTCTTCGAGAACCGGTTCATGCACTGCCTGGAGATGCAGCGCATGGGTGCCGACATCCAGAT
CGAAGGGGCCCGGGCGCGCATCCGCGGCGTCGAGAAGCTGACCGCGGCGCCGGTGATCGCCACCGATCTGCGCGCCTCGG
CGAGTCTGGTGCTGGCCGGGCTGGTGGCCGAGGGTGAGACCCGGGTGGACCGGATCTACCACATCGACCGCGGCTACGAG
TGCATCGAGGAGAAGCTCGCCCAGCTCGGTGCCGATATCCAGCGCGTCCCCGACTGA

Upstream 100 bases:

>100_bases
GCCCTGCGCGCCCACATTGATGACGACACCCTACACGCCATCTCCATGCGGACCCTGACGCCTCCGGAGCACGAGCAACA
GCAGAAGGCGGGGTAGGCCG

Downstream 100 bases:

>100_bases
CGACGGAGACCGATCGAATACCATGAGCCGAACCCTGACCCTGGCCCTGTCCAAGGGGCGCATCCTGGAAGAGACCCTGC
CGCTGCTGGCGCGCTGCGGG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MERLLIRGGNPLRGDIRISGAKNAALPVMAATLLADGPTTVGNIPHLHDVTTTMELLGRMGVELTVHEGMEVEVNTATIH
SFRAPYELVKTMRASILVLGPLLARFGQAEVSLPGGCAIGSRPVNIHVDGLRAMGAEIEVRDGYIKGRADRLQGAHIRMD
VSTVTGTENLMMAAALARGTTVLENAAREPEVINLADCINAMGGHVQGAGTSTITIEGVDTLRGVHHRVLPDRIETGTYL
VAAAMTGGEVRLKDTAPELVESVLGKLRESGAEVSAGRDWVTLRMEGRPRAVDLETAPYPGFPTDMQAQFCALNAISTGE
GTVTETVFENRFMHCLEMQRMGADIQIEGARARIRGVEKLTAAPVIATDLRASASLVLAGLVAEGETRVDRIYHIDRGYE
CIEEKLAQLGADIQRVPD

Sequences:

>Translated_418_residues
MERLLIRGGNPLRGDIRISGAKNAALPVMAATLLADGPTTVGNIPHLHDVTTTMELLGRMGVELTVHEGMEVEVNTATIH
SFRAPYELVKTMRASILVLGPLLARFGQAEVSLPGGCAIGSRPVNIHVDGLRAMGAEIEVRDGYIKGRADRLQGAHIRMD
VSTVTGTENLMMAAALARGTTVLENAAREPEVINLADCINAMGGHVQGAGTSTITIEGVDTLRGVHHRVLPDRIETGTYL
VAAAMTGGEVRLKDTAPELVESVLGKLRESGAEVSAGRDWVTLRMEGRPRAVDLETAPYPGFPTDMQAQFCALNAISTGE
GTVTETVFENRFMHCLEMQRMGADIQIEGARARIRGVEKLTAAPVIATDLRASASLVLAGLVAEGETRVDRIYHIDRGYE
CIEEKLAQLGADIQRVPD
>Mature_418_residues
MERLLIRGGNPLRGDIRISGAKNAALPVMAATLLADGPTTVGNIPHLHDVTTTMELLGRMGVELTVHEGMEVEVNTATIH
SFRAPYELVKTMRASILVLGPLLARFGQAEVSLPGGCAIGSRPVNIHVDGLRAMGAEIEVRDGYIKGRADRLQGAHIRMD
VSTVTGTENLMMAAALARGTTVLENAAREPEVINLADCINAMGGHVQGAGTSTITIEGVDTLRGVHHRVLPDRIETGTYL
VAAAMTGGEVRLKDTAPELVESVLGKLRESGAEVSAGRDWVTLRMEGRPRAVDLETAPYPGFPTDMQAQFCALNAISTGE
GTVTETVFENRFMHCLEMQRMGADIQIEGARARIRGVEKLTAAPVIATDLRASASLVLAGLVAEGETRVDRIYHIDRGYE
CIEEKLAQLGADIQRVPD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=55.0239234449761, Blast_Score=464, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_HALHL (A1WYW6)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003680.1
- ProteinModelPortal:   A1WYW6
- SMR:   A1WYW6
- STRING:   A1WYW6
- GeneID:   4711267
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_2114
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   ICGDTDG
- PhylomeDB:   A1WYW6
- ProtClustDB:   PRK09369
- BioCyc:   HHAL349124:HHAL_2114-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44751; Mature: 44751

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLLIRGGNPLRGDIRISGAKNAALPVMAATLLADGPTTVGNIPHLHDVTTTMELLGRM
CCEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GVELTVHEGMEVEVNTATIHSFRAPYELVKTMRASILVLGPLLARFGQAEVSLPGGCAIG
CCEEEEECCCEEEEEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEC
SRPVNIHVDGLRAMGAEIEVRDGYIKGRADRLQGAHIRMDVSTVTGTENLMMAAALARGT
CCEEEEEECCHHHCCCEEEEECCEEECCHHHCCCCEEEEEEEEECCCHHHHHHHHHHCCC
TVLENAAREPEVINLADCINAMGGHVQGAGTSTITIEGVDTLRGVHHRVLPDRIETGTYL
HHHHHCCCCCCEEEHHHHHHHHCCCEECCCCCEEEEECHHHHHHHHHHCCCCHHCCCCEE
VAAAMTGGEVRLKDTAPELVESVLGKLRESGAEVSAGRDWVTLRMEGRPRAVDLETAPYP
EEEEECCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
GFPTDMQAQFCALNAISTGEGTVTETVFENRFMHCLEMQRMGADIQIEGARARIRGVEKL
CCCCCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
TAAPVIATDLRASASLVLAGLVAEGETRVDRIYHIDRGYECIEEKLAQLGADIQRVPD
HCCCEEEHHHHHHHHHHEEHHHHCCCHHHHHEEEECCCHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MERLLIRGGNPLRGDIRISGAKNAALPVMAATLLADGPTTVGNIPHLHDVTTTMELLGRM
CCEEEEECCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHC
GVELTVHEGMEVEVNTATIHSFRAPYELVKTMRASILVLGPLLARFGQAEVSLPGGCAIG
CCEEEEECCCEEEEEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEC
SRPVNIHVDGLRAMGAEIEVRDGYIKGRADRLQGAHIRMDVSTVTGTENLMMAAALARGT
CCEEEEEECCHHHCCCEEEEECCEEECCHHHCCCCEEEEEEEEECCCHHHHHHHHHHCCC
TVLENAAREPEVINLADCINAMGGHVQGAGTSTITIEGVDTLRGVHHRVLPDRIETGTYL
HHHHHCCCCCCEEEHHHHHHHHCCCEECCCCCEEEEECHHHHHHHHHHCCCCHHCCCCEE
VAAAMTGGEVRLKDTAPELVESVLGKLRESGAEVSAGRDWVTLRMEGRPRAVDLETAPYP
EEEEECCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
GFPTDMQAQFCALNAISTGEGTVTETVFENRFMHCLEMQRMGADIQIEGARARIRGVEKL
CCCCCCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHH
TAAPVIATDLRASASLVLAGLVAEGETRVDRIYHIDRGYECIEEKLAQLGADIQRVPD
HCCCEEEHHHHHHHHHHEEHHHHCCCHHHHHEEEECCCHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA