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The map label for this gene is phbC [H]

Identifier: 121998852

GI number: 121998852

Start: 2277537

End: 2279342

Strand: Reverse

Name: phbC [H]

Synonym: Hhal_2073

Alternate gene names: 121998852

Gene position: 2279342-2277537 (Counterclockwise)

Preceding gene: 121998854

Following gene: 121998851

Centisome position: 85.1

GC content: 63.57

Gene sequence:

>1806_bases
ATGGCACAAGAGAATGGCACCCGGAACCAGGATATCGACTACGAGGCGCTCGCCCGGTCGCTGACGGAGATCACCGCCAA
GAGCCAGGAGCTGGTGCAGGACTTCCTGCAGCAGGAACAGTCGGCGCACCACTTGGCCATGGAGGACGCGGCGCAGATGG
CGCAGCTGTTCCAACAGCTGGCGGCGCGCGTGATGGCCGACCCGGCGCGGCTGATGCAGATGCAGATGGCCTTCTGGCAG
AACTACATGGGGCTGATGCAGAACGTTGCCCTGCGCTTCTGGGGGCTGGAGTCCGAGCCGGTGGCGCAGCCGGCCAAGGG
CGATCGCCGCTTCCAGCACCAGGGCTGGGAGGATCACCCGTTCTTCGATTTCGTCAAGCAGTCCTACCTCCTGGCGGCGG
ATCATACCCATGCGGTGGTCCGTGACGTGGAAGGGCTCGACGATCAGACCAAGAAGAAGGTGGATTTCTACACCCGGGCG
TTCATCGACGCCATGGCCCCGTCGAACTTCGTCGCCACCAACCCCGAGGTGCTTCAGAAGACCGTCGACACCGGCGGCCA
GAACCTGCTGCAGGGACTCAACAACCTGCTGGACGACCTCAAGCGCGGTCGCGGGCGGCTCGATATCCGCATGACAGACT
ACGACGCCTTCGAGGTCGGCACCAATCTCGCGACCACCCCGGGCCAGGTCGTCTACCAGAACGAGTTGATGCAGCTCATC
CAGTATGAGCCCACCACCACCGAGGTGCACAAGCGCCCGCTGCTGCTGGTGCCGGCGTGGATCAACAAGTACTACATCAT
GGACCTGAACGACGAGAAGTCCATGGTGAAGTGGCTGGTGGACCAGGGCCACACGGTGTTCATCATCTCCTGGCGCAATC
CCGACGAGAGCCTGGCCGAGAAGCAATTCGAGGACTACATGCTCGAGGGACCGGTGACGGCCATGGACGTGGTCCAGGAG
ATCACCGGCAGCGAGGAGATGAACCTGGTCGGCTACTGCCTGGGCGGGACCCTCTCGGCCTGCACCCTGGCCTGGCTGGC
GGCCCGCGGCGATCGGCGCATCCAGGCGGCCACCTTCCTCACCTGCATGCTGGATTTCGAGTATCCGGGCGAACTCGAGG
TCTTCCTCGACGAGGAGCAGATCTCCACGCTGGAGCGGCGCATGGGCCAGAAGGGCTACCTGGAAGGTCGCTACATGTCC
ACGACCTTCAACATGCTCCGCGCCAACGACCTGATCTGGTCGTTCTTCGTGAACAACTACCTTAAGGGCGATGAGCCGTT
CCCCTTCGATCTGCTCTACTGGAACTCCGATTCCACCAACATGCCGGCCAAGATGCACAGCTTCTACCTTCGCAACATGT
ACCAGCGCAATCTGCTCAAGGAGCCGGGTGGGCTGGAGCTGGCCGGCGAGGCCATCGACCTGGGCAAAATCGACATTCCG
GCCTACTTCATGTCGGCCAAGGAGGACCACATCGCCCCCTGGAAGAGCACCATCCGGGGCCCGCGGTTGCTCTCCGGTCC
CACCCGCTACGTCCTGGGTGGCTCCGGCCATATCGCCGGGGTGATCAACCCGCCCCACAAGAACAAGTACGGCTACTGGA
CGAACACCGCCAAGACGGTGGACCAGGACGAGTGGCTGGAAGGGGCCGAGCCCCACGAGGGGTCATGGTGGAACGACTGG
GGGCAGTGGCTCGCCGGGTACGGCGGTGACAAGGTGAAGGCGCGCAAGGTCGGCTCGAAGAAGCATGCGCCGATCGAGCC
GGCACCCGGCTCCTATGTGCGACACGGCGTGCTCTACGACGACTGA

Upstream 100 bases:

>100_bases
GGATCGGTTGATGCATCGCAACGCAACCCTGCGTGCATTACTATGTTCCCCCGGAGATATGACACCCTCGGGGCGCGTAG
CCCCGATCGCGAGGAGCGGT

Downstream 100 bases:

>100_bases
GCCCGCCCACGGGCCGGGGTGGCGTGGGGCGCCACCCCGGCTTAAACTCAACACTCCAGTGAACGGTGCGAGCAGCGCGT
TGCCATGGACGTGACCTCCT

Product: poly(R)-hydroxyalkanoic acid synthase, class I

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MAQENGTRNQDIDYEALARSLTEITAKSQELVQDFLQQEQSAHHLAMEDAAQMAQLFQQLAARVMADPARLMQMQMAFWQ
NYMGLMQNVALRFWGLESEPVAQPAKGDRRFQHQGWEDHPFFDFVKQSYLLAADHTHAVVRDVEGLDDQTKKKVDFYTRA
FIDAMAPSNFVATNPEVLQKTVDTGGQNLLQGLNNLLDDLKRGRGRLDIRMTDYDAFEVGTNLATTPGQVVYQNELMQLI
QYEPTTTEVHKRPLLLVPAWINKYYIMDLNDEKSMVKWLVDQGHTVFIISWRNPDESLAEKQFEDYMLEGPVTAMDVVQE
ITGSEEMNLVGYCLGGTLSACTLAWLAARGDRRIQAATFLTCMLDFEYPGELEVFLDEEQISTLERRMGQKGYLEGRYMS
TTFNMLRANDLIWSFFVNNYLKGDEPFPFDLLYWNSDSTNMPAKMHSFYLRNMYQRNLLKEPGGLELAGEAIDLGKIDIP
AYFMSAKEDHIAPWKSTIRGPRLLSGPTRYVLGGSGHIAGVINPPHKNKYGYWTNTAKTVDQDEWLEGAEPHEGSWWNDW
GQWLAGYGGDKVKARKVGSKKHAPIEPAPGSYVRHGVLYDD

Sequences:

>Translated_601_residues
MAQENGTRNQDIDYEALARSLTEITAKSQELVQDFLQQEQSAHHLAMEDAAQMAQLFQQLAARVMADPARLMQMQMAFWQ
NYMGLMQNVALRFWGLESEPVAQPAKGDRRFQHQGWEDHPFFDFVKQSYLLAADHTHAVVRDVEGLDDQTKKKVDFYTRA
FIDAMAPSNFVATNPEVLQKTVDTGGQNLLQGLNNLLDDLKRGRGRLDIRMTDYDAFEVGTNLATTPGQVVYQNELMQLI
QYEPTTTEVHKRPLLLVPAWINKYYIMDLNDEKSMVKWLVDQGHTVFIISWRNPDESLAEKQFEDYMLEGPVTAMDVVQE
ITGSEEMNLVGYCLGGTLSACTLAWLAARGDRRIQAATFLTCMLDFEYPGELEVFLDEEQISTLERRMGQKGYLEGRYMS
TTFNMLRANDLIWSFFVNNYLKGDEPFPFDLLYWNSDSTNMPAKMHSFYLRNMYQRNLLKEPGGLELAGEAIDLGKIDIP
AYFMSAKEDHIAPWKSTIRGPRLLSGPTRYVLGGSGHIAGVINPPHKNKYGYWTNTAKTVDQDEWLEGAEPHEGSWWNDW
GQWLAGYGGDKVKARKVGSKKHAPIEPAPGSYVRHGVLYDD
>Mature_600_residues
AQENGTRNQDIDYEALARSLTEITAKSQELVQDFLQQEQSAHHLAMEDAAQMAQLFQQLAARVMADPARLMQMQMAFWQN
YMGLMQNVALRFWGLESEPVAQPAKGDRRFQHQGWEDHPFFDFVKQSYLLAADHTHAVVRDVEGLDDQTKKKVDFYTRAF
IDAMAPSNFVATNPEVLQKTVDTGGQNLLQGLNNLLDDLKRGRGRLDIRMTDYDAFEVGTNLATTPGQVVYQNELMQLIQ
YEPTTTEVHKRPLLLVPAWINKYYIMDLNDEKSMVKWLVDQGHTVFIISWRNPDESLAEKQFEDYMLEGPVTAMDVVQEI
TGSEEMNLVGYCLGGTLSACTLAWLAARGDRRIQAATFLTCMLDFEYPGELEVFLDEEQISTLERRMGQKGYLEGRYMST
TFNMLRANDLIWSFFVNNYLKGDEPFPFDLLYWNSDSTNMPAKMHSFYLRNMYQRNLLKEPGGLELAGEAIDLGKIDIPA
YFMSAKEDHIAPWKSTIRGPRLLSGPTRYVLGGSGHIAGVINPPHKNKYGYWTNTAKTVDQDEWLEGAEPHEGSWWNDWG
QWLAGYGGDKVKARKVGSKKHAPIEPAPGSYVRHGVLYDD

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 68501; Mature: 68370

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQENGTRNQDIDYEALARSLTEITAKSQELVQDFLQQEQSAHHLAMEDAAQMAQLFQQL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARVMADPARLMQMQMAFWQNYMGLMQNVALRFWGLESEPVAQPAKGDRRFQHQGWEDHP
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCC
FFDFVKQSYLLAADHTHAVVRDVEGLDDQTKKKVDFYTRAFIDAMAPSNFVATNPEVLQK
HHHHHHHHHEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
TVDTGGQNLLQGLNNLLDDLKRGRGRLDIRMTDYDAFEVGTNLATTPGQVVYQNELMQLI
HHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHCCCCCCCCCCCEEHHHHHHHH
QYEPTTTEVHKRPLLLVPAWINKYYIMDLNDEKSMVKWLVDQGHTVFIISWRNPDESLAE
HCCCCCHHHHCCCEEEEEHHHCCEEEEECCCHHHHHHHHHCCCCEEEEEEECCCCHHHHH
KQFEDYMLEGPVTAMDVVQEITGSEEMNLVGYCLGGTLSACTLAWLAARGDRRIQAATFL
HHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHEE
TCMLDFEYPGELEVFLDEEQISTLERRMGQKGYLEGRYMSTTFNMLRANDLIWSFFVNNY
EHEEECCCCCCEEEEECHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
LKGDEPFPFDLLYWNSDSTNMPAKMHSFYLRNMYQRNLLKEPGGLELAGEAIDLGKIDIP
CCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCEEECCCCCCC
AYFMSAKEDHIAPWKSTIRGPRLLSGPTRYVLGGSGHIAGVINPPHKNKYGYWTNTAKTV
HHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEECCCCCCC
DQDEWLEGAEPHEGSWWNDWGQWLAGYGGDKVKARKVGSKKHAPIEPAPGSYVRHGVLYD
CHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEHHHCCCCCCCCCCCCCCHHHHCCCCCC
D
C
>Mature Secondary Structure 
AQENGTRNQDIDYEALARSLTEITAKSQELVQDFLQQEQSAHHLAMEDAAQMAQLFQQL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AARVMADPARLMQMQMAFWQNYMGLMQNVALRFWGLESEPVAQPAKGDRRFQHQGWEDHP
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCC
FFDFVKQSYLLAADHTHAVVRDVEGLDDQTKKKVDFYTRAFIDAMAPSNFVATNPEVLQK
HHHHHHHHHEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
TVDTGGQNLLQGLNNLLDDLKRGRGRLDIRMTDYDAFEVGTNLATTPGQVVYQNELMQLI
HHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHCCCCCCCCCCCEEHHHHHHHH
QYEPTTTEVHKRPLLLVPAWINKYYIMDLNDEKSMVKWLVDQGHTVFIISWRNPDESLAE
HCCCCCHHHHCCCEEEEEHHHCCEEEEECCCHHHHHHHHHCCCCEEEEEEECCCCHHHHH
KQFEDYMLEGPVTAMDVVQEITGSEEMNLVGYCLGGTLSACTLAWLAARGDRRIQAATFL
HHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHHEE
TCMLDFEYPGELEVFLDEEQISTLERRMGQKGYLEGRYMSTTFNMLRANDLIWSFFVNNY
EHEEECCCCCCEEEEECHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHH
LKGDEPFPFDLLYWNSDSTNMPAKMHSFYLRNMYQRNLLKEPGGLELAGEAIDLGKIDIP
CCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCEEECCCCCCC
AYFMSAKEDHIAPWKSTIRGPRLLSGPTRYVLGGSGHIAGVINPPHKNKYGYWTNTAKTV
HHHHCCCCCCCCCHHHHCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCEECCCCCCC
DQDEWLEGAEPHEGSWWNDWGQWLAGYGGDKVKARKVGSKKHAPIEPAPGSYVRHGVLYD
CHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCEEHHHCCCCCCCCCCCCCCHHHHCCCCCC
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748438 [H]