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The map label for this gene is cysQ [H]

Identifier: 121998837

GI number: 121998837

Start: 2260483

End: 2261307

Strand: Reverse

Name: cysQ [H]

Synonym: Hhal_2058

Alternate gene names: 121998837

Gene position: 2261307-2260483 (Counterclockwise)

Preceding gene: 121998838

Following gene: 121998836

Centisome position: 84.43

GC content: 71.88

Gene sequence:

>825_bases
ATGGCAGAGCAACCGTGGCAGCACTGGCTGGAGCCGGTGCGGGAGATCGCCGAGCAGGCCGGCGAACGCATCATGGCCGT
CTACCGTACCGCCGATTTCGAGGTGGAGGCCAAGGCGGACGACAGCCCGCTGACCCGGGCCGACCAGGCCGCCCACGACG
CCATCAAGGCCGGGCTTACCGCGCTGACCCCCGATCTGCCCCAGCTCTCCGAGGAGGGCGAGGACATCGATCCTGCCGAA
CGGCAGGCGTGGCGGCAGTACTGGCTGATCGACCCGCTGGACGGAACCCGGGAGTTCATCAAGCGCAACGGCGAGTTCAC
CGTCAACATCGCCCTGGTGGTCGATGGTCGGCCGGTGCTCGGTGTGGTCCACGCCCCGGACCTGGGGGTGACCTGGGCGG
CGACGGCCGGCGTAGACGCCTGGCGCGAGGCCGGCGGCCAGCGCCACAGCATCCGCACGCGCGCCGCCGCGTCGCCGCTG
ACCGCCGTCGTCAGTCGCTCCCACCGCGAGGCAGCGGTGGCCGATATCCTCGCCCGCCTCGGGGACTACCGCGAGCTTTC
GGTGGGCAGTTCGCTGAAGATCTGCCGCATCGCCGAGGGCGAGGCCGATCTCTACCCGCGCTTCGGGCCCACCTGCGAGT
GGGATACCGGGGCCGCGCAGTGCGTGCTGGAGGTCGCCGGCGGTTGCCTGATGGACGTCGGCGGCGAGCCGCTGCGCTAC
AACACCGGTGCCTCGCTGCTCAACCCGGACTTCATCGCCGTGGGCGACCCGGCCTACGACTGGGCGCGGGTCACCGACGG
GCTCCCCTGGGAGGCGCGGCGCTAG

Upstream 100 bases:

>100_bases
GATCTGACCGAGGCACGCTCGATCACCGCGCTTTATCTGGCGCGGGATCATCTGGCAGGGCGCGCGGCGTAACCCGCGCC
GGAACAACACGGAAGGGATC

Downstream 100 bases:

>100_bases
GCCGCCAGTCGGGCACTTGTGATTGTGGAGTCTCACCCGCATCATTAGGGGAGAGCAGGTTGTTCCGCAGCGGAGGTAAC
CCCAGTGGCCGAGTCCATGG

Product: 3'(2'),5'-bisphosphate nucleotidase

Products: NA

Alternate protein names: 3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase; 3'-phosphoadenosine 5'-phosphate phosphatase; PAP phosphatase; DPNPase [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MAEQPWQHWLEPVREIAEQAGERIMAVYRTADFEVEAKADDSPLTRADQAAHDAIKAGLTALTPDLPQLSEEGEDIDPAE
RQAWRQYWLIDPLDGTREFIKRNGEFTVNIALVVDGRPVLGVVHAPDLGVTWAATAGVDAWREAGGQRHSIRTRAAASPL
TAVVSRSHREAAVADILARLGDYRELSVGSSLKICRIAEGEADLYPRFGPTCEWDTGAAQCVLEVAGGCLMDVGGEPLRY
NTGASLLNPDFIAVGDPAYDWARVTDGLPWEARR

Sequences:

>Translated_274_residues
MAEQPWQHWLEPVREIAEQAGERIMAVYRTADFEVEAKADDSPLTRADQAAHDAIKAGLTALTPDLPQLSEEGEDIDPAE
RQAWRQYWLIDPLDGTREFIKRNGEFTVNIALVVDGRPVLGVVHAPDLGVTWAATAGVDAWREAGGQRHSIRTRAAASPL
TAVVSRSHREAAVADILARLGDYRELSVGSSLKICRIAEGEADLYPRFGPTCEWDTGAAQCVLEVAGGCLMDVGGEPLRY
NTGASLLNPDFIAVGDPAYDWARVTDGLPWEARR
>Mature_273_residues
AEQPWQHWLEPVREIAEQAGERIMAVYRTADFEVEAKADDSPLTRADQAAHDAIKAGLTALTPDLPQLSEEGEDIDPAER
QAWRQYWLIDPLDGTREFIKRNGEFTVNIALVVDGRPVLGVVHAPDLGVTWAATAGVDAWREAGGQRHSIRTRAAASPLT
AVVSRSHREAAVADILARLGDYRELSVGSSLKICRIAEGEADLYPRFGPTCEWDTGAAQCVLEVAGGCLMDVGGEPLRYN
TGASLLNPDFIAVGDPAYDWARVTDGLPWEARR

Specific function: Converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP. May also convert adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) [H]

COG id: COG1218

COG function: function code P; 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI221625487, Length=244, Percent_Identity=26.6393442622951, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI5031789, Length=244, Percent_Identity=26.6393442622951, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI116812595, Length=287, Percent_Identity=27.1777003484321, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1790659, Length=246, Percent_Identity=52.4390243902439, Blast_Score=226, Evalue=9e-61,
Organism=Escherichia coli, GI1788882, Length=226, Percent_Identity=27.4336283185841, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71995905, Length=267, Percent_Identity=28.4644194756554, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71995897, Length=267, Percent_Identity=28.4644194756554, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17537869, Length=215, Percent_Identity=29.3023255813954, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320493, Length=212, Percent_Identity=28.7735849056604, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24651149, Length=295, Percent_Identity=27.1186440677966, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641722, Length=265, Percent_Identity=27.1698113207547, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24664922, Length=269, Percent_Identity=23.4200743494424, Blast_Score=71, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006240
- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.7 [H]

Molecular weight: Translated: 29927; Mature: 29795

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQPWQHWLEPVREIAEQAGERIMAVYRTADFEVEAKADDSPLTRADQAAHDAIKAGLT
CCCCCHHHHHHHHHHHHHHHHHHEEEHEEECCEEEEECCCCCCCHHHHHHHHHHHHHCHH
ALTPDLPQLSEEGEDIDPAERQAWRQYWLIDPLDGTREFIKRNGEFTVNIALVVDGRPVL
HCCCCCHHHHHCCCCCCHHHHHHHHHHEECCCCCHHHHHHHCCCCEEEEEEEEECCCCEE
GVVHAPDLGVTWAATAGVDAWREAGGQRHSIRTRAAASPLTAVVSRSHREAAVADILARL
EEEECCCCCEEEEHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GDYRELSVGSSLKICRIAEGEADLYPRFGPTCEWDTGAAQCVLEVAGGCLMDVGGEPLRY
CCCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCEEE
NTGASLLNPDFIAVGDPAYDWARVTDGLPWEARR
CCCCCCCCCCEEEECCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AEQPWQHWLEPVREIAEQAGERIMAVYRTADFEVEAKADDSPLTRADQAAHDAIKAGLT
CCCCHHHHHHHHHHHHHHHHHHEEEHEEECCEEEEECCCCCCCHHHHHHHHHHHHHCHH
ALTPDLPQLSEEGEDIDPAERQAWRQYWLIDPLDGTREFIKRNGEFTVNIALVVDGRPVL
HCCCCCHHHHHCCCCCCHHHHHHHHHHEECCCCCHHHHHHHCCCCEEEEEEEEECCCCEE
GVVHAPDLGVTWAATAGVDAWREAGGQRHSIRTRAAASPLTAVVSRSHREAAVADILARL
EEEECCCCCEEEEHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
GDYRELSVGSSLKICRIAEGEADLYPRFGPTCEWDTGAAQCVLEVAGGCLMDVGGEPLRY
CCCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCEEE
NTGASLLNPDFIAVGDPAYDWARVTDGLPWEARR
CCCCCCCCCCEEEECCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]