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The map label for this gene is efp

Identifier: 121998758

GI number: 121998758

Start: 2181041

End: 2181610

Strand: Reverse

Name: efp

Synonym: Hhal_1979

Alternate gene names: 121998758

Gene position: 2181610-2181041 (Counterclockwise)

Preceding gene: 121998760

Following gene: 121998757

Centisome position: 81.45

GC content: 62.63

Gene sequence:

>570_bases
ATGGCGACCTATAGCACCAACGAGTTTAAGGGCGGGCTCAAGATTATGCTCGACGGGGATCCTTTCACCATCGTCGAGAA
CGAGTTCGTCAAGCCCGGCAAGGGGCAGGCCTTCAACCGGGTCAAGCTGCGCAATCTGAAGACCAATCGTGTCGTCGAGA
AGACGTTCAAGTCCGGCGAGAGCGTCGAGGCGGCCGACGTCATGGAGACCGAACTCCAGTATCTCTACAACGACGGCGAG
TTCTGGTACTTCATGGATCCCACCTCCTTCGAGCAGAAGGCGGCCCCGAGCAGTGCCGTGGGGGATGCCGCCAACTGGAT
CAAGGAGCAGGATACCTGCACCGTCATCCTGTGGAACGACACCCCGCTGCAGGTGGAGGCGCCGAACTTCGTCGACCTCA
AGGTCATCGAGACCGATCCGGGCGTGCGCGGGGATACCAGCAGCGGCGGGACCAAGCCGGCCAAGCTGGAGACCGGCGCC
ACGGTGCGCGTGCCCCTGTTCATCGAGGAAGGCGAGGTGCTGCGCGTCGATACCCGCAAGGCGGAGTACGTCAGCCGCGC
CAAGGACTGA

Upstream 100 bases:

>100_bases
TCCTGCCGCCAGCGCTCGGCGGCGCGGCGCTCTCTGCCTGGCTTGGGCTGTCGGGCCGTATCGGTTAGCATCGCGTCAAC
TTCGCATACCCGAGGGGATT

Downstream 100 bases:

>100_bases
TGGCGGCCGGCGGTCCGTGCGGCGCCGCCGACGGCGCCACCGTGCGCCGGGTCGGTCAGAAGCTGGCACGGATCCGCGGC
TTCTTCGCCGAGCGCGGGGT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MATYSTNEFKGGLKIMLDGDPFTIVENEFVKPGKGQAFNRVKLRNLKTNRVVEKTFKSGESVEAADVMETELQYLYNDGE
FWYFMDPTSFEQKAAPSSAVGDAANWIKEQDTCTVILWNDTPLQVEAPNFVDLKVIETDPGVRGDTSSGGTKPAKLETGA
TVRVPLFIEEGEVLRVDTRKAEYVSRAKD

Sequences:

>Translated_189_residues
MATYSTNEFKGGLKIMLDGDPFTIVENEFVKPGKGQAFNRVKLRNLKTNRVVEKTFKSGESVEAADVMETELQYLYNDGE
FWYFMDPTSFEQKAAPSSAVGDAANWIKEQDTCTVILWNDTPLQVEAPNFVDLKVIETDPGVRGDTSSGGTKPAKLETGA
TVRVPLFIEEGEVLRVDTRKAEYVSRAKD
>Mature_188_residues
ATYSTNEFKGGLKIMLDGDPFTIVENEFVKPGKGQAFNRVKLRNLKTNRVVEKTFKSGESVEAADVMETELQYLYNDGEF
WYFMDPTSFEQKAAPSSAVGDAANWIKEQDTCTVILWNDTPLQVEAPNFVDLKVIETDPGVRGDTSSGGTKPAKLETGAT
VRVPLFIEEGEVLRVDTRKAEYVSRAKD

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=188, Percent_Identity=59.5744680851064, Blast_Score=244, Evalue=2e-66,
Organism=Escherichia coli, GI87082061, Length=185, Percent_Identity=26.4864864864865, Blast_Score=84, Evalue=9e-18,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_HALHL (A1WYI1)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003545.1
- ProteinModelPortal:   A1WYI1
- SMR:   A1WYI1
- STRING:   A1WYI1
- GeneID:   4710334
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1979
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- PhylomeDB:   A1WYI1
- ProtClustDB:   PRK00529
- BioCyc:   HHAL349124:HHAL_1979-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 21043; Mature: 20912

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYSTNEFKGGLKIMLDGDPFTIVENEFVKPGKGQAFNRVKLRNLKTNRVVEKTFKSGE
CCCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCC
SVEAADVMETELQYLYNDGEFWYFMDPTSFEQKAAPSSAVGDAANWIKEQDTCTVILWND
CCCHHHHHHHHHHEEEECCCEEEEECCCCCHHHCCCCCCCCHHHHHHCCCCCEEEEEECC
TPLQVEAPNFVDLKVIETDPGVRGDTSSGGTKPAKLETGATVRVPLFIEEGEVLRVDTRK
CCEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEECCCCEEEEECCH
AEYVSRAKD
HHHHHHCCC
>Mature Secondary Structure 
ATYSTNEFKGGLKIMLDGDPFTIVENEFVKPGKGQAFNRVKLRNLKTNRVVEKTFKSGE
CCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCC
SVEAADVMETELQYLYNDGEFWYFMDPTSFEQKAAPSSAVGDAANWIKEQDTCTVILWND
CCCHHHHHHHHHHEEEECCCEEEEECCCCCHHHCCCCCCCCHHHHHHCCCCCEEEEEECC
TPLQVEAPNFVDLKVIETDPGVRGDTSSGGTKPAKLETGATVRVPLFIEEGEVLRVDTRK
CCEEEECCCEEEEEEEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEECCCCEEEEECCH
AEYVSRAKD
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA