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The map label for this gene is btuB [H]

Identifier: 121998705

GI number: 121998705

Start: 2120645

End: 2122528

Strand: Reverse

Name: btuB [H]

Synonym: Hhal_1926

Alternate gene names: 121998705

Gene position: 2122528-2120645 (Counterclockwise)

Preceding gene: 121998709

Following gene: 121998704

Centisome position: 79.24

GC content: 63.91

Gene sequence:

>1884_bases
ATGCCCAGCAACACCACCAGCCGGGTCGCCGCGGGTGTGGCGGCCGGTCTTGCCGTAAGTGCCGGCCCGGCGATCGCCGA
TACCGACGGGGAGTCCGCACAACTCGCGCCCCTCGTGGTCACGCCAACTCGAATGGCCCAGACCGTCGATGAGTCCCTGT
CCTCCGTCTCCGTCATCGACCGCGAGCAGATCGACCGCCAGCAGCCTCGGCAGGTCTCGGATCTGCTGCAGGGTCAGGCG
GGGTCGAGCCTGACGACGTCGGGTCCGTTCGGCAAGAGCACCAGTCTGTTCATGCGCGGTACCAACTCTGACCATACCCT
GTTGCTGGTCGATGGGGTGCCGATGAATTCGGCGACGCAAGGAGGGGCCGCCTGGCAATATCTGCCTCCTGCCGAGATTG
ACCGCATCGAGGTGGTGCGCGGGCCGCGCACCAGCGTCTACGGCGCCGACGCCGTCGGCGGTGTGGTCCAGGTCTTCACC
CGCCAGGGGGAGGAGGGCCCTCCGCGCTTCCGTGCCTTCGGCGGCGCCGGGTCGTTCAACACCCACGAATTCGGTTTGGG
TGTCTCTGGCGGGACTGCGGCTAGCCGCTACGCCCTCTCGGCCAGCCACTACGAGACGGACGGGATCAACGTCCAGGACG
GTGAGGGAGATGAGGACCCCGACGGCTTTGAGAACACCAGCTTCAGCGGCCGTTTCAGCCATCGGCTACCCGGCGGTGCC
GAACTCTTCGCGACGGGGTTCCGCTCAGAGGGTACAAACGAGTTCGACGGGACAAGACTTGGCGAAGAGGACTGGACGGA
TCACTACTTCCAGGCCCTCCGTGGCGGCGTCCGCGGGGACCTCACCGAGCGCTGGTTCAGCGAGCTGGCGGTCTCCCAGG
CGAAGGATGAGCAGGATAACGTCGATAGCCGGGGAGAGACATGGCAGTACACTGAACGCCACGAGGTAAGTTGGCGGAAT
GAGCTGTATTGGGGCGCCGGGCATGTCTGGGCCTTTGGCGGTGACTGGCGAGATGAGAAAGTCGACACCGCCGACGATTA
TGACGAAACCAGCCGGTACAACGCCGGTGCGTATTCGCAGCTCGAGTTGGATTTAGGCCGACATGACCTCGGTGCCAGCC
TGCGTTACGACGACAACGAGGCTTACGGTGACAACGTGACCGGTCAGGTCGCCTGGGGCTTTGACGCAACGGATCGACTT
CGGCTGCGTTCGAGCTACGGCACGGCTTTCAAGGCGCCGACATTCAACGACCTGTATGCACCTGAAAACCCGAATTGGTT
GCTTGCCGGAGGAAATACGGACCTTGAGGCCGAGACGTCCGCTTCTGCGGAGGTGGGTGCACGCTGGCAGGTCAGAAGGG
GCTATGTGGATGCAGCGCTGTTCCGGACGGACATCGACAATTTGATCGCTGATAAGCCAGTGGATGGTCAGCAGGATTGG
ACGCAGCCTGGCAATGTCGAAGAGGCCCGCATCCGCGGTGCCGAGCTGGAGGCGGGGGCGCACTGGCAGGAATGGCAGTT
TTCTGGCGCGTTCACCTACCTCGATCACGAGGACCGGGAGACGGGTGAGGAGTTGCTTCGGCGCCCGAGTGAGTCGTTCC
GATTGGAAATCGATCGCGAGCTGGGGGATTTTTCCTTGGGGGCCACTGGCCTGCTGCGGGGGCGAAGCTATGACACCGAT
TTTGATATGGCTACCAGTCAGTCGGAACGCGTGCGCCTCTCCGGCTACGGCCTCCTCAATCTCCGCACCAGCTACGCCAT
CACCCCGGAGTGGACCCTGCGCGGGACGCTGGAGAACGCCCTGGACAAGGAGTACGAGACGGTGGGCGGCTACAACCAGC
CGGGGCGGGCGGTGTACGTCTCGCTGCACTTCAATCAGCAGTAG

Upstream 100 bases:

>100_bases
TGCCGGGCGCAAGCGCGAACCCTTCCCCCATCCCTGTCTTCCTCCCTGCGGTGTAACCGGACCGACGCGCGTGCGGGTGG
CGCGCGGAAGGGAGGAAAGC

Downstream 100 bases:

>100_bases
CAGGTAGGCAGTTGGAGCAGTGCTCAGCGCGCGGCTGGAGAGCCGGCATCTTCAGCCGCCGCCTCGGGCAGGAAATGGAT
CAAGACCGGAGCACGGAGGA

Product: TonB-dependent receptor

Products: NA

Alternate protein names: Cobalamin receptor; Outer membrane cobalamin translocator [H]

Number of amino acids: Translated: 627; Mature: 626

Protein sequence:

>627_residues
MPSNTTSRVAAGVAAGLAVSAGPAIADTDGESAQLAPLVVTPTRMAQTVDESLSSVSVIDREQIDRQQPRQVSDLLQGQA
GSSLTTSGPFGKSTSLFMRGTNSDHTLLLVDGVPMNSATQGGAAWQYLPPAEIDRIEVVRGPRTSVYGADAVGGVVQVFT
RQGEEGPPRFRAFGGAGSFNTHEFGLGVSGGTAASRYALSASHYETDGINVQDGEGDEDPDGFENTSFSGRFSHRLPGGA
ELFATGFRSEGTNEFDGTRLGEEDWTDHYFQALRGGVRGDLTERWFSELAVSQAKDEQDNVDSRGETWQYTERHEVSWRN
ELYWGAGHVWAFGGDWRDEKVDTADDYDETSRYNAGAYSQLELDLGRHDLGASLRYDDNEAYGDNVTGQVAWGFDATDRL
RLRSSYGTAFKAPTFNDLYAPENPNWLLAGGNTDLEAETSASAEVGARWQVRRGYVDAALFRTDIDNLIADKPVDGQQDW
TQPGNVEEARIRGAELEAGAHWQEWQFSGAFTYLDHEDRETGEELLRRPSESFRLEIDRELGDFSLGATGLLRGRSYDTD
FDMATSQSERVRLSGYGLLNLRTSYAITPEWTLRGTLENALDKEYETVGGYNQPGRAVYVSLHFNQQ

Sequences:

>Translated_627_residues
MPSNTTSRVAAGVAAGLAVSAGPAIADTDGESAQLAPLVVTPTRMAQTVDESLSSVSVIDREQIDRQQPRQVSDLLQGQA
GSSLTTSGPFGKSTSLFMRGTNSDHTLLLVDGVPMNSATQGGAAWQYLPPAEIDRIEVVRGPRTSVYGADAVGGVVQVFT
RQGEEGPPRFRAFGGAGSFNTHEFGLGVSGGTAASRYALSASHYETDGINVQDGEGDEDPDGFENTSFSGRFSHRLPGGA
ELFATGFRSEGTNEFDGTRLGEEDWTDHYFQALRGGVRGDLTERWFSELAVSQAKDEQDNVDSRGETWQYTERHEVSWRN
ELYWGAGHVWAFGGDWRDEKVDTADDYDETSRYNAGAYSQLELDLGRHDLGASLRYDDNEAYGDNVTGQVAWGFDATDRL
RLRSSYGTAFKAPTFNDLYAPENPNWLLAGGNTDLEAETSASAEVGARWQVRRGYVDAALFRTDIDNLIADKPVDGQQDW
TQPGNVEEARIRGAELEAGAHWQEWQFSGAFTYLDHEDRETGEELLRRPSESFRLEIDRELGDFSLGATGLLRGRSYDTD
FDMATSQSERVRLSGYGLLNLRTSYAITPEWTLRGTLENALDKEYETVGGYNQPGRAVYVSLHFNQQ
>Mature_626_residues
PSNTTSRVAAGVAAGLAVSAGPAIADTDGESAQLAPLVVTPTRMAQTVDESLSSVSVIDREQIDRQQPRQVSDLLQGQAG
SSLTTSGPFGKSTSLFMRGTNSDHTLLLVDGVPMNSATQGGAAWQYLPPAEIDRIEVVRGPRTSVYGADAVGGVVQVFTR
QGEEGPPRFRAFGGAGSFNTHEFGLGVSGGTAASRYALSASHYETDGINVQDGEGDEDPDGFENTSFSGRFSHRLPGGAE
LFATGFRSEGTNEFDGTRLGEEDWTDHYFQALRGGVRGDLTERWFSELAVSQAKDEQDNVDSRGETWQYTERHEVSWRNE
LYWGAGHVWAFGGDWRDEKVDTADDYDETSRYNAGAYSQLELDLGRHDLGASLRYDDNEAYGDNVTGQVAWGFDATDRLR
LRSSYGTAFKAPTFNDLYAPENPNWLLAGGNTDLEAETSASAEVGARWQVRRGYVDAALFRTDIDNLIADKPVDGQQDWT
QPGNVEEARIRGAELEAGAHWQEWQFSGAFTYLDHEDRETGEELLRRPSESFRLEIDRELGDFSLGATGLLRGRSYDTDF
DMATSQSERVRLSGYGLLNLRTSYAITPEWTLRGTLENALDKEYETVGGYNQPGRAVYVSLHFNQQ

Specific function: Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB [H]

COG id: COG4206

COG function: function code H; Outer membrane cobalamin receptor protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790405, Length=612, Percent_Identity=29.5751633986928, Blast_Score=216, Evalue=4e-57,
Organism=Escherichia coli, GI1788478, Length=689, Percent_Identity=26.2699564586357, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1786798, Length=123, Percent_Identity=36.5853658536585, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787723, Length=209, Percent_Identity=28.2296650717703, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 68788; Mature: 68657

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSNTTSRVAAGVAAGLAVSAGPAIADTDGESAQLAPLVVTPTRMAQTVDESLSSVSVID
CCCCCHHHHHHHHHHHHEEECCCCEECCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHH
REQIDRQQPRQVSDLLQGQAGSSLTTSGPFGKSTSLFMRGTNSDHTLLLVDGVPMNSATQ
HHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCC
GGAAWQYLPPAEIDRIEVVRGPRTSVYGADAVGGVVQVFTRQGEEGPPRFRAFGGAGSFN
CCCEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCC
THEFGLGVSGGTAASRYALSASHYETDGINVQDGEGDEDPDGFENTSFSGRFSHRLPGGA
CCEECCCCCCCCCHHHEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCH
ELFATGFRSEGTNEFDGTRLGEEDWTDHYFQALRGGVRGDLTERWFSELAVSQAKDEQDN
HEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
VDSRGETWQYTERHEVSWRNELYWGAGHVWAFGGDWRDEKVDTADDYDETSRYNAGAYSQ
CCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCEE
LELDLGRHDLGASLRYDDNEAYGDNVTGQVAWGFDATDRLRLRSSYGTAFKAPTFNDLYA
EEEECCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCCCEEEECCCCCEECCCCCCCCCC
PENPNWLLAGGNTDLEAETSASAEVGARWQVRRGYVDAALFRTDIDNLIADKPVDGQQDW
CCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCC
TQPGNVEEARIRGAELEAGAHWQEWQFSGAFTYLDHEDRETGEELLRRPSESFRLEIDRE
CCCCCCHHHHCCCCCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHCCCCCEEEEEECC
LGDFSLGATGLLRGRSYDTDFDMATSQSERVRLSGYGLLNLRTSYAITPEWTLRGTLENA
CCCCCCCCHHEECCCCCCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCEEECCHHHHH
LDKEYETVGGYNQPGRAVYVSLHFNQQ
HHHHHHHHCCCCCCCCEEEEEEEECCC
>Mature Secondary Structure 
PSNTTSRVAAGVAAGLAVSAGPAIADTDGESAQLAPLVVTPTRMAQTVDESLSSVSVID
CCCCHHHHHHHHHHHHEEECCCCEECCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHH
REQIDRQQPRQVSDLLQGQAGSSLTTSGPFGKSTSLFMRGTNSDHTLLLVDGVPMNSATQ
HHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCC
GGAAWQYLPPAEIDRIEVVRGPRTSVYGADAVGGVVQVFTRQGEEGPPRFRAFGGAGSFN
CCCEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCC
THEFGLGVSGGTAASRYALSASHYETDGINVQDGEGDEDPDGFENTSFSGRFSHRLPGGA
CCEECCCCCCCCCHHHEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEECCCCCCCH
ELFATGFRSEGTNEFDGTRLGEEDWTDHYFQALRGGVRGDLTERWFSELAVSQAKDEQDN
HEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCC
VDSRGETWQYTERHEVSWRNELYWGAGHVWAFGGDWRDEKVDTADDYDETSRYNAGAYSQ
CCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCCCCCCCCCCCCCHHHCCCCCCCCEE
LELDLGRHDLGASLRYDDNEAYGDNVTGQVAWGFDATDRLRLRSSYGTAFKAPTFNDLYA
EEEECCCCCCCCCEEECCCCCCCCCCCEEEEECCCCCCCEEEECCCCCEECCCCCCCCCC
PENPNWLLAGGNTDLEAETSASAEVGARWQVRRGYVDAALFRTDIDNLIADKPVDGQQDW
CCCCCEEEECCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCC
TQPGNVEEARIRGAELEAGAHWQEWQFSGAFTYLDHEDRETGEELLRRPSESFRLEIDRE
CCCCCCHHHHCCCCCCCCCCCCCEEEECCEEEEECCCCHHHHHHHHHCCCCCEEEEEECC
LGDFSLGATGLLRGRSYDTDFDMATSQSERVRLSGYGLLNLRTSYAITPEWTLRGTLENA
CCCCCCCCHHEECCCCCCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCEEECCHHHHH
LDKEYETVGGYNQPGRAVYVSLHFNQQ
HHHHHHHHCCCCCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA