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The map label for this gene is ybaL [H]

Identifier: 121998642

GI number: 121998642

Start: 2036462

End: 2038138

Strand: Reverse

Name: ybaL [H]

Synonym: Hhal_1863

Alternate gene names: 121998642

Gene position: 2038138-2036462 (Counterclockwise)

Preceding gene: 121998643

Following gene: 121998641

Centisome position: 76.09

GC content: 64.4

Gene sequence:

>1677_bases
ATGGCCGACATCCCCGCTGTCGAAGGACTGTTCAACCAATTCGCCATCCTGCTGCTGGTGGCAGCCGTCATCGGCTTTAT
CGGAACCCGACTCAAGCAGCCGCTGATCGTCTCGTTCATCGCCGTCGGCATCCTGGTCGGGCCGTCTGCCCTGGGGTGGG
TGGACGGACACGAGCCGATGATGGATCTGCTGGCCGAGATCGGCATCGCCCTGTTGCTGTTCATCGTCGGTCTAAAGCTC
GATCTACACCTGATCCGGACCATGGGGCCGGTGGCCTTGGCGACCGGGCTAGGGCAGGTGCTGTTTACCTCGGCGGTGGG
GTTCCTGATCGCGCTGGCTCTGGGGATGGAGCCGATCACGGCGCTCTACGTGGCGGTCGCGCTGACCTTCTCGAGCACCA
TTATCATCGTCAAGCTGCTCTCCGATAAGAAGGAGATCGACGCCCTGCACGGGCGGATCGCCATCGGCTTTCTGATCGTG
CAGGACATCTGTGTAGTCCTGGCCATGATCCTGATCACCTCGCTGGCCGCTGGCGAGGGGGATGCCAACGTGGCCATGGA
GGTGGGGCAGGTGCTGCTCACCGGTGTGGCCATGCTGCTGTTCGTGGCCCTGATGATGCGCTATGTGCTGCCGCCGCTTC
TCAACATGCTGGCGCGTACGCCGGAGCTCTTGGTGCTTTTCTCCATCGCCCTGGCGGTGGCCATGGCTACCGGCGGCGAT
CTGATGGGCTTCAGCAAGGAGGTGGGTGCCTTCCTGGCGGGTATTGCCATTGCCTCGACGCCCTACCGGGAGGCGGTGGC
CTCGCGCCTGACGGCGCTGCGGGATTTCCTGCTGCTGTTCTTCTTCATCTCGCTGGGCGCGCAGCTGGATATGGGCACCA
TCGGTGATCAGGTGGTGCCGGCGCTGATCTTCTCGACCTTCGTACTCATCGGCAACCCGATCATCGTGCTGATCATCATG
GGGTACATGGGGTACCGCAAGCGGACCGGTTTCCTGGCCGGACTGACGGTGGCGCAGATCTCCGAGTTCTCGTTGATCCT
GGCCGCCCTGGGCATGTCGGTGGGTCACATCGGGCAGGACACCATGGGCCTGGTCACGCTGGTGGGCCTGATCACCATCG
GTGCCTCCACCTACATGATCCTCTACTCCAAGCCGCTCTACGAACGCCTGGCGCCGCTTCTGTCGGTCTTCGAGCGCAAG
GTCCCGCACGCCGAGATCGCCCTGGACAGCCAGCCGGATCAGCACTATGAAGCGGATGTGGTCATCTTCGGATTGGGCCG
CTACGGCCACCAGCTGGCCAAGAACTTCAAGGCCCGGGGCTGGCGAGTGCTGGGCGTGGACTTTGACCCGACGCTGGTGG
GACAGTGGCGGGAAGAGGGGCACATGGCCCATTACGGAGACGCCTCCGACCCGGAGTTCCCGCAGACCCTGCCCCTGGCG
CGGGCGCGGTGGGTGATCAGTACGGTGCCCGACCGGGATATCGGCGCGACGCTGATCAGCGCCCTGCGGAGTGCCGGTTA
TCAGGGCAAGGTGGCGGTGACTTCCCACTCGCGGATGGACGCCGATTATCTGCGGGGACAGGGGCCTGATCGCATCCTGT
TGCCCTTCGTCGATGCCGCGGAGATGGCCGTGGCCGGAATCACCGGGGGGCAGGAGAGAGGAGGGGGCGGACGATGA

Upstream 100 bases:

>100_bases
CGGGGTGGTGCTGGTGACCGCCGAGATGCTGGGCCAGGAAGTGGCCCACGTGCGCTGAACTCGGCGATTCACGCCGTTTT
TTCCATATCAGGATTTTTGC

Downstream 100 bases:

>100_bases
GCCTCAGGCAGATCCTTTTCGCCAGTGATCTCTCGCCGCAGGCGGCGCTGGCCGGCGAGCGGGCCGCGCAGCTGGCCGGA
GAGACCGGAGCAGGCCTTGG

Product: sodium/hydrogen exchanger

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 557

Protein sequence:

>558_residues
MADIPAVEGLFNQFAILLLVAAVIGFIGTRLKQPLIVSFIAVGILVGPSALGWVDGHEPMMDLLAEIGIALLLFIVGLKL
DLHLIRTMGPVALATGLGQVLFTSAVGFLIALALGMEPITALYVAVALTFSSTIIIVKLLSDKKEIDALHGRIAIGFLIV
QDICVVLAMILITSLAAGEGDANVAMEVGQVLLTGVAMLLFVALMMRYVLPPLLNMLARTPELLVLFSIALAVAMATGGD
LMGFSKEVGAFLAGIAIASTPYREAVASRLTALRDFLLLFFFISLGAQLDMGTIGDQVVPALIFSTFVLIGNPIIVLIIM
GYMGYRKRTGFLAGLTVAQISEFSLILAALGMSVGHIGQDTMGLVTLVGLITIGASTYMILYSKPLYERLAPLLSVFERK
VPHAEIALDSQPDQHYEADVVIFGLGRYGHQLAKNFKARGWRVLGVDFDPTLVGQWREEGHMAHYGDASDPEFPQTLPLA
RARWVISTVPDRDIGATLISALRSAGYQGKVAVTSHSRMDADYLRGQGPDRILLPFVDAAEMAVAGITGGQERGGGGR

Sequences:

>Translated_558_residues
MADIPAVEGLFNQFAILLLVAAVIGFIGTRLKQPLIVSFIAVGILVGPSALGWVDGHEPMMDLLAEIGIALLLFIVGLKL
DLHLIRTMGPVALATGLGQVLFTSAVGFLIALALGMEPITALYVAVALTFSSTIIIVKLLSDKKEIDALHGRIAIGFLIV
QDICVVLAMILITSLAAGEGDANVAMEVGQVLLTGVAMLLFVALMMRYVLPPLLNMLARTPELLVLFSIALAVAMATGGD
LMGFSKEVGAFLAGIAIASTPYREAVASRLTALRDFLLLFFFISLGAQLDMGTIGDQVVPALIFSTFVLIGNPIIVLIIM
GYMGYRKRTGFLAGLTVAQISEFSLILAALGMSVGHIGQDTMGLVTLVGLITIGASTYMILYSKPLYERLAPLLSVFERK
VPHAEIALDSQPDQHYEADVVIFGLGRYGHQLAKNFKARGWRVLGVDFDPTLVGQWREEGHMAHYGDASDPEFPQTLPLA
RARWVISTVPDRDIGATLISALRSAGYQGKVAVTSHSRMDADYLRGQGPDRILLPFVDAAEMAVAGITGGQERGGGGR
>Mature_557_residues
ADIPAVEGLFNQFAILLLVAAVIGFIGTRLKQPLIVSFIAVGILVGPSALGWVDGHEPMMDLLAEIGIALLLFIVGLKLD
LHLIRTMGPVALATGLGQVLFTSAVGFLIALALGMEPITALYVAVALTFSSTIIIVKLLSDKKEIDALHGRIAIGFLIVQ
DICVVLAMILITSLAAGEGDANVAMEVGQVLLTGVAMLLFVALMMRYVLPPLLNMLARTPELLVLFSIALAVAMATGGDL
MGFSKEVGAFLAGIAIASTPYREAVASRLTALRDFLLLFFFISLGAQLDMGTIGDQVVPALIFSTFVLIGNPIIVLIIMG
YMGYRKRTGFLAGLTVAQISEFSLILAALGMSVGHIGQDTMGLVTLVGLITIGASTYMILYSKPLYERLAPLLSVFERKV
PHAEIALDSQPDQHYEADVVIFGLGRYGHQLAKNFKARGWRVLGVDFDPTLVGQWREEGHMAHYGDASDPEFPQTLPLAR
ARWVISTVPDRDIGATLISALRSAGYQGKVAVTSHSRMDADYLRGQGPDRILLPFVDAAEMAVAGITGGQERGGGGR

Specific function: Unknown

COG id: COG0475

COG function: function code P; Kef-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI157388921, Length=363, Percent_Identity=24.7933884297521, Blast_Score=102, Evalue=1e-21,
Organism=Escherichia coli, GI1786685, Length=528, Percent_Identity=26.3257575757576, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786232, Length=485, Percent_Identity=25.979381443299, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1789749, Length=513, Percent_Identity=23.0019493177388, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6322367, Length=407, Percent_Identity=22.3587223587224, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 59484; Mature: 59353

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIPAVEGLFNQFAILLLVAAVIGFIGTRLKQPLIVSFIAVGILVGPSALGWVDGHEPM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCCCCCHHH
MDLLAEIGIALLLFIVGLKLDLHLIRTMGPVALATGLGQVLFTSAVGFLIALALGMEPIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ALYVAVALTFSSTIIIVKLLSDKKEIDALHGRIAIGFLIVQDICVVLAMILITSLAAGEG
HHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DANVAMEVGQVLLTGVAMLLFVALMMRYVLPPLLNMLARTPELLVLFSIALAVAMATGGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
LMGFSKEVGAFLAGIAIASTPYREAVASRLTALRDFLLLFFFISLGAQLDMGTIGDQVVP
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ALIFSTFVLIGNPIIVLIIMGYMGYRKRTGFLAGLTVAQISEFSLILAALGMSVGHIGQD
HHHHHHHHHHCCHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TMGLVTLVGLITIGASTYMILYSKPLYERLAPLLSVFERKVPHAEIALDSQPDQHYEADV
HHHHHHHHHHHHHCCHHEEEEECCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCE
VIFGLGRYGHQLAKNFKARGWRVLGVDFDPTLVGQWREEGHMAHYGDASDPEFPQTLPLA
EEEECCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCHH
RARWVISTVPDRDIGATLISALRSAGYQGKVAVTSHSRMDADYLRGQGPDRILLPFVDAA
HHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCEEEEECCCHH
EMAVAGITGGQERGGGGR
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
ADIPAVEGLFNQFAILLLVAAVIGFIGTRLKQPLIVSFIAVGILVGPSALGWVDGHEPM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCCCCCHHH
MDLLAEIGIALLLFIVGLKLDLHLIRTMGPVALATGLGQVLFTSAVGFLIALALGMEPIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ALYVAVALTFSSTIIIVKLLSDKKEIDALHGRIAIGFLIVQDICVVLAMILITSLAAGEG
HHHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DANVAMEVGQVLLTGVAMLLFVALMMRYVLPPLLNMLARTPELLVLFSIALAVAMATGGD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
LMGFSKEVGAFLAGIAIASTPYREAVASRLTALRDFLLLFFFISLGAQLDMGTIGDQVVP
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
ALIFSTFVLIGNPIIVLIIMGYMGYRKRTGFLAGLTVAQISEFSLILAALGMSVGHIGQD
HHHHHHHHHHCCHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TMGLVTLVGLITIGASTYMILYSKPLYERLAPLLSVFERKVPHAEIALDSQPDQHYEADV
HHHHHHHHHHHHHCCHHEEEEECCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCE
VIFGLGRYGHQLAKNFKARGWRVLGVDFDPTLVGQWREEGHMAHYGDASDPEFPQTLPLA
EEEECCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCEECCCCCCCCCCCCCCHH
RARWVISTVPDRDIGATLISALRSAGYQGKVAVTSHSRMDADYLRGQGPDRILLPFVDAA
HHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHCCCCCCEEEEECCCHH
EMAVAGITGGQERGGGGR
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7721718 [H]