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The map label for this gene is asd [H]

Identifier: 121998587

GI number: 121998587

Start: 1981131

End: 1982153

Strand: Reverse

Name: asd [H]

Synonym: Hhal_1808

Alternate gene names: 121998587

Gene position: 1982153-1981131 (Counterclockwise)

Preceding gene: 121998589

Following gene: 121998586

Centisome position: 74.0

GC content: 66.37

Gene sequence:

>1023_bases
ATGAGCAAGCAGTACGATGTCGCCGTAGTCGGGGCCACCGGCGCGGTCGGAGAGGTGATGCTCTCCATTCTGGCCGAGCG
CGGCTTCCCCGCGCGCAAGATCTACCCGCTGGCCAGTGCCCGCTCCGCCGGGCGGACGGTATCCTTCGCCGGGCAGGAGC
TGGAGATCCAGGACCTGGCCCAGTTCGACTTCTCCCAGGTGCAGATCGCGCTCTTCTCCGCCGGGGGGTCCATCTCCGCC
GAGCACGCACCGCGGGCGGCCGAGGCCGGGGCGGTGGTGATCGACAACACCTCCCACTTTCGCTACGACGACGACATCCC
GTTGATCATTCCCGAGGTCAACCCGCACGCGGTGGCTGGCTACAAGAAGCGGGGGATCATCGCCAATCCCAACTGTTCCA
CCATCCAGATGCTCGTGGCCCTCAAGCCGATCCACGACGCCGTGGGCATCGAGCGGATCAACGTGGCCACTTACCAGGCG
GTCTCCGGCAGTGGCAAGCCGGCCATCGACGAGCTCAACGCCCAGAGCCGGGCGATCCTCGACGGCGGTGAGCCGCAGTG
TGCTGAGTACCCGAAGCCCATCGCGTTCAATTGCCTGCCGCACATCGACGATTTCCAGGACAACGGCTACACCAAGGAAG
AGATGAAGATGGTCTGGGAGACCATCAAGATCTTCGAGGACTCCTCCGTTCGGGTGAATCCCACCACGGTGCGTGTGCCG
GTGGTCTACGGCCACTCCGAGGCCGTGCACATCGAGACCCGCGAGCGCATCACCGCCGAGCGTGCCCGGCAGGTGCTCTC
CAGCGCCCCCGGGGTCGAGGTCCTGGACGAGCGCACAGGCGGCGGCTATCCGACGGCGCTGACGGAGGCCGCCGGACGCG
ATCCGGTCTACGTCGGGCGCATCCGCGAGGACATCAGCCACGAGCGGGGTCTCGATCTCTGGGTGGTGGCCGATAACGTC
CGCAAGGGGGCGGCGCTGAACAGCGTGCAGATTGCGGAGCTGCTGATTGGCGAACACATCTGA

Upstream 100 bases:

>100_bases
TTGAGCGTGCCATGGGCTGAGAGCAATTGCCGCTCTGGCAATCCCGCGCAGTGCGTTAGTAGACTTGGCCTGACTAGGAC
CAGCGAGCACGGGAGCATCC

Downstream 100 bases:

>100_bases
CAGCGGACGAAGGGGCGAGCCCGTGCGCAAGGCGATCCGCGGCCTCGCCGGCCTGGCGGGACTGTCACTGGTCTCAGTGG
CAGCCGCGGTGGAGGTCAGC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSKQYDVAVVGATGAVGEVMLSILAERGFPARKIYPLASARSAGRTVSFAGQELEIQDLAQFDFSQVQIALFSAGGSISA
EHAPRAAEAGAVVIDNTSHFRYDDDIPLIIPEVNPHAVAGYKKRGIIANPNCSTIQMLVALKPIHDAVGIERINVATYQA
VSGSGKPAIDELNAQSRAILDGGEPQCAEYPKPIAFNCLPHIDDFQDNGYTKEEMKMVWETIKIFEDSSVRVNPTTVRVP
VVYGHSEAVHIETRERITAERARQVLSSAPGVEVLDERTGGGYPTALTEAAGRDPVYVGRIREDISHERGLDLWVVADNV
RKGAALNSVQIAELLIGEHI

Sequences:

>Translated_340_residues
MSKQYDVAVVGATGAVGEVMLSILAERGFPARKIYPLASARSAGRTVSFAGQELEIQDLAQFDFSQVQIALFSAGGSISA
EHAPRAAEAGAVVIDNTSHFRYDDDIPLIIPEVNPHAVAGYKKRGIIANPNCSTIQMLVALKPIHDAVGIERINVATYQA
VSGSGKPAIDELNAQSRAILDGGEPQCAEYPKPIAFNCLPHIDDFQDNGYTKEEMKMVWETIKIFEDSSVRVNPTTVRVP
VVYGHSEAVHIETRERITAERARQVLSSAPGVEVLDERTGGGYPTALTEAAGRDPVYVGRIREDISHERGLDLWVVADNV
RKGAALNSVQIAELLIGEHI
>Mature_339_residues
SKQYDVAVVGATGAVGEVMLSILAERGFPARKIYPLASARSAGRTVSFAGQELEIQDLAQFDFSQVQIALFSAGGSISAE
HAPRAAEAGAVVIDNTSHFRYDDDIPLIIPEVNPHAVAGYKKRGIIANPNCSTIQMLVALKPIHDAVGIERINVATYQAV
SGSGKPAIDELNAQSRAILDGGEPQCAEYPKPIAFNCLPHIDDFQDNGYTKEEMKMVWETIKIFEDSSVRVNPTTVRVPV
VYGHSEAVHIETRERITAERARQVLSSAPGVEVLDERTGGGYPTALTEAAGRDPVYVGRIREDISHERGLDLWVVADNVR
KGAALNSVQIAELLIGEHI

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=342, Percent_Identity=39.1812865497076, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789841, Length=356, Percent_Identity=28.0898876404494, Blast_Score=96, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320362, Length=409, Percent_Identity=27.3838630806846, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 36752; Mature: 36621

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKQYDVAVVGATGAVGEVMLSILAERGFPARKIYPLASARSAGRTVSFAGQELEIQDLA
CCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCEEEECCCCCCHHHHH
QFDFSQVQIALFSAGGSISAEHAPRAAEAGAVVIDNTSHFRYDDDIPLIIPEVNPHAVAG
HCCCCCEEEEEEECCCCCCCCCCCCCHHCCEEEEECCCCEEECCCCCEEEECCCCCEECC
YKKRGIIANPNCSTIQMLVALKPIHDAVGIERINVATYQAVSGSGKPAIDELNAQSRAIL
CCCCCEEECCCCHHEEEEEHHHHHHHHHCCEEEEEEEEEEECCCCCCCHHHCCCCCEEEE
DGGEPQCAEYPKPIAFNCLPHIDDFQDNGYTKEEMKMVWETIKIFEDSSVRVNPTTVRVP
CCCCCCHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCEEEEEE
VVYGHSEAVHIETRERITAERARQVLSSAPGVEVLDERTGGGYPTALTEAAGRDPVYVGR
EEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHCCCCCEEEHH
IREDISHERGLDLWVVADNVRKGAALNSVQIAELLIGEHI
HHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SKQYDVAVVGATGAVGEVMLSILAERGFPARKIYPLASARSAGRTVSFAGQELEIQDLA
CCCEEEEEEECCCHHHHHHHHHHHHCCCCHHEEEECCCCCCCCCEEEECCCCCCHHHHH
QFDFSQVQIALFSAGGSISAEHAPRAAEAGAVVIDNTSHFRYDDDIPLIIPEVNPHAVAG
HCCCCCEEEEEEECCCCCCCCCCCCCHHCCEEEEECCCCEEECCCCCEEEECCCCCEECC
YKKRGIIANPNCSTIQMLVALKPIHDAVGIERINVATYQAVSGSGKPAIDELNAQSRAIL
CCCCCEEECCCCHHEEEEEHHHHHHHHHCCEEEEEEEEEEECCCCCCCHHHCCCCCEEEE
DGGEPQCAEYPKPIAFNCLPHIDDFQDNGYTKEEMKMVWETIKIFEDSSVRVNPTTVRVP
CCCCCCHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECCEEEEEE
VVYGHSEAVHIETRERITAERARQVLSSAPGVEVLDERTGGGYPTALTEAAGRDPVYVGR
EEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHCCCCCEEEHH
IREDISHERGLDLWVVADNVRKGAALNSVQIAELLIGEHI
HHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9573067 [H]