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The map label for this gene is pdxH

Identifier: 121998561

GI number: 121998561

Start: 1956386

End: 1956991

Strand: Reverse

Name: pdxH

Synonym: Hhal_1782

Alternate gene names: 121998561

Gene position: 1956991-1956386 (Counterclockwise)

Preceding gene: 121998562

Following gene: 121998560

Centisome position: 73.06

GC content: 68.81

Gene sequence:

>606_bases
ATGACTGAGCCGGGGATGGATTCGGACACGATCTATCAGGAGGCCCTGAGCCGCGTGCACCAGGTACTGGAGCGGGCCCG
GGCCACGGATCTGCCGGAGCCCACCGCGGGCATCCTGGCGACGGTGGGACGCGACGGGTGGCCGGCAGCGCGGACGGTGC
TCCTCAAGCAGCTCGACGAGCAGGGTGCCGTTTTCTACACCAACCGTGCCAGTCGCAAGGGGCAGCAACTGGCCGATAAC
CCCCGTGCGGCGCTGTGCCTGCACTTCCAGCCGCTCTACGAGCAGGTGGAGATCCGCGGCGTGGTGGCCGCGGTGAGCGC
CAGCGAGGCGGATCGCTACTGGGCGCAGCGGGAGCGGTTGAGCCAGTTGGGGGCTTGGGCCTCTCACCAGTCGGAGCCGC
TGGCCAGTCGTCACGAGCTGGAGGCCCGCCTGGAGGAGGTCGAGTCGCGTTTCCCCGAGCGTGTACCCCGCCCCCCGCAC
TGGTCGGGGTACCGTATAATCCCGGTCAGCATTGAGCTCTGGTCGGCCGGGGATGGCCGCCTGCATCAGCGCGAGCGATA
CGAGCACCGGACGGACGGCTGGAGCCATTTCCTACTCAACCCGTGA

Upstream 100 bases:

>100_bases
GCCGGCGAGCGCTGGAATGCCGTGGCGGTGAGCCCGGTGCGTAGCGGCGAGCGGGTGCGCGTGGTCAGTAAGGAAGGACT
GACACTGAAGGTGGAGCCCA

Downstream 100 bases:

>100_bases
GGGACGTTTCTTCGGGCGAAAGGGAGCGTAATGGAGGATCTTTCCAGGTATTCGGCCGAGCAGCTGCGTGGACTGCGCGA
GGAGGTGGAACGGGAGATCG

Product: pyridoxamine-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MTEPGMDSDTIYQEALSRVHQVLERARATDLPEPTAGILATVGRDGWPAARTVLLKQLDEQGAVFYTNRASRKGQQLADN
PRAALCLHFQPLYEQVEIRGVVAAVSASEADRYWAQRERLSQLGAWASHQSEPLASRHELEARLEEVESRFPERVPRPPH
WSGYRIIPVSIELWSAGDGRLHQRERYEHRTDGWSHFLLNP

Sequences:

>Translated_201_residues
MTEPGMDSDTIYQEALSRVHQVLERARATDLPEPTAGILATVGRDGWPAARTVLLKQLDEQGAVFYTNRASRKGQQLADN
PRAALCLHFQPLYEQVEIRGVVAAVSASEADRYWAQRERLSQLGAWASHQSEPLASRHELEARLEEVESRFPERVPRPPH
WSGYRIIPVSIELWSAGDGRLHQRERYEHRTDGWSHFLLNP
>Mature_200_residues
TEPGMDSDTIYQEALSRVHQVLERARATDLPEPTAGILATVGRDGWPAARTVLLKQLDEQGAVFYTNRASRKGQQLADNP
RAALCLHFQPLYEQVEIRGVVAAVSASEADRYWAQRERLSQLGAWASHQSEPLASRHELEARLEEVESRFPERVPRPPHW
SGYRIIPVSIELWSAGDGRLHQRERYEHRTDGWSHFLLNP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family

Homologues:

Organism=Homo sapiens, GI8922498, Length=162, Percent_Identity=40.1234567901235, Blast_Score=122, Evalue=3e-28,
Organism=Escherichia coli, GI1787926, Length=201, Percent_Identity=37.8109452736318, Blast_Score=136, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17553712, Length=173, Percent_Identity=36.9942196531792, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6319509, Length=158, Percent_Identity=37.3417721518987, Blast_Score=110, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45551845, Length=166, Percent_Identity=36.7469879518072, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24644901, Length=166, Percent_Identity=36.7469879518072, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXH_HALHL (A1WXY4)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003348.1
- ProteinModelPortal:   A1WXY4
- SMR:   A1WXY4
- STRING:   A1WXY4
- GeneID:   4710598
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1782
- eggNOG:   COG0259
- HOGENOM:   HBG327559
- OMA:   HWSGFRI
- PhylomeDB:   A1WXY4
- ProtClustDB:   CLSK727536
- BioCyc:   HHAL349124:HHAL_1782-MONOMER
- HAMAP:   MF_01629
- InterPro:   IPR000659
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002
- Gene3D:   G3DSA:2.30.110.10
- PANTHER:   PTHR10851
- PIRSF:   PIRSF000190

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase; SSF50475 FMN_binding

EC number: =1.4.3.5

Molecular weight: Translated: 22898; Mature: 22767

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: BINDING 51-51 BINDING 54-54 BINDING 56-56 BINDING 73-73 BINDING 113-113 BINDING 117-117 BINDING 121-121

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPGMDSDTIYQEALSRVHQVLERARATDLPEPTAGILATVGRDGWPAARTVLLKQLDE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCC
QGAVFYTNRASRKGQQLADNPRAALCLHFQPLYEQVEIRGVVAAVSASEADRYWAQRERL
CCCEEEECCCCCCCHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLGAWASHQSEPLASRHELEARLEEVESRFPERVPRPPHWSGYRIIPVSIELWSAGDGR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCC
LHQRERYEHRTDGWSHFLLNP
HHHHHHHHHHCCCCCEECCCC
>Mature Secondary Structure 
TEPGMDSDTIYQEALSRVHQVLERARATDLPEPTAGILATVGRDGWPAARTVLLKQLDE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHCC
QGAVFYTNRASRKGQQLADNPRAALCLHFQPLYEQVEIRGVVAAVSASEADRYWAQRERL
CCCEEEECCCCCCCHHHHCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLGAWASHQSEPLASRHELEARLEEVESRFPERVPRPPHWSGYRIIPVSIELWSAGDGR
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCCCC
LHQRERYEHRTDGWSHFLLNP
HHHHHHHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA