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The map label for this gene is cysH1 [H]

Identifier: 121998556

GI number: 121998556

Start: 1952059

End: 1952775

Strand: Reverse

Name: cysH1 [H]

Synonym: Hhal_1777

Alternate gene names: 121998556

Gene position: 1952775-1952059 (Counterclockwise)

Preceding gene: 121998560

Following gene: 121998555

Centisome position: 72.91

GC content: 66.81

Gene sequence:

>717_bases
ATGGCGATCGTAGATGAGCCATCGGACATCGCTGCGCTGGAGCAGCGTATAGAGGGGACTGTCGCCATCCTGCGCCGGGT
GGAGGCGGAGTATCTGCCTGCGGTGCTGGCTTCGAGTTTCAGCGCCGAGGATATGGTCCTGCTCGATCTCATTCGGGCGC
ACACCCCCGGGATTGACGCATTTACCTTAGATACTGGGCGGCTCAACGCCGAGACGTACAAGCTGCAGCAGAGGGTGCGG
GAACGCTACGGCCCGGTGGTGCGGACCTACTACCCCGAGGCGTTCGAGGTCGAGCAGGTGGTGGCGTCTTTCGGGGTCAA
CGGGTTCTACCATAGCCTTGAGGCTCGGCAGGCGTGCTGCCACGCGCGCAAGGTAGAGCCGCTGCGCCGGGCGCTCAGCG
GCCAGCGCGCCTGGCTGACCGGGATGCGCCGGGCCCAGGCAGCGACCCGGAGCGAGTTACCGATCGAGGAGCACGACCCA
GAGCAGGGGCTGATCAAGCTCAACCCGCTGGCGGAGTGGCAGGAGGCCGACGTGTGGGGTTATCTGCGCAGCCACGGCGT
GCCTTACAACAAGCTCTACGATCAGGGGTACCGCAGTATCGGTTGCGCGCCATGCACCCGCCCGGTAGCCGCCGGCGAGG
ATATCCGTGCCGGGCGCTGGTGGTGGGAGCACCCCGCGCGGCGCGAGTGCGGTCTGCACCGGAGTCCCCAGGATTGA

Upstream 100 bases:

>100_bases
CGCCGTTGCGTCTCATTCTTGGGTGACGTCAGTAATCAGGCGGCGCGGGGCGAGGTCCGAGCCGCTCTAGGTGTAACGGC
CAACGGAGGTGCGTGCGCCC

Downstream 100 bases:

>100_bases
GCGGCGGGTCCGCGCCGCCAGGGGAAAGCCACAAAGCCGTGACAGATTCCTGCCCGGGCCGGTAGAATACCCGCGTTCAC
GCGCCGCAGGGCGCGGCTTG

Product: adenylylsulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MAIVDEPSDIAALEQRIEGTVAILRRVEAEYLPAVLASSFSAEDMVLLDLIRAHTPGIDAFTLDTGRLNAETYKLQQRVR
ERYGPVVRTYYPEAFEVEQVVASFGVNGFYHSLEARQACCHARKVEPLRRALSGQRAWLTGMRRAQAATRSELPIEEHDP
EQGLIKLNPLAEWQEADVWGYLRSHGVPYNKLYDQGYRSIGCAPCTRPVAAGEDIRAGRWWWEHPARRECGLHRSPQD

Sequences:

>Translated_238_residues
MAIVDEPSDIAALEQRIEGTVAILRRVEAEYLPAVLASSFSAEDMVLLDLIRAHTPGIDAFTLDTGRLNAETYKLQQRVR
ERYGPVVRTYYPEAFEVEQVVASFGVNGFYHSLEARQACCHARKVEPLRRALSGQRAWLTGMRRAQAATRSELPIEEHDP
EQGLIKLNPLAEWQEADVWGYLRSHGVPYNKLYDQGYRSIGCAPCTRPVAAGEDIRAGRWWWEHPARRECGLHRSPQD
>Mature_237_residues
AIVDEPSDIAALEQRIEGTVAILRRVEAEYLPAVLASSFSAEDMVLLDLIRAHTPGIDAFTLDTGRLNAETYKLQQRVRE
RYGPVVRTYYPEAFEVEQVVASFGVNGFYHSLEARQACCHARKVEPLRRALSGQRAWLTGMRRAQAATRSELPIEEHDPE
QGLIKLNPLAEWQEADVWGYLRSHGVPYNKLYDQGYRSIGCAPCTRPVAAGEDIRAGRWWWEHPARRECGLHRSPQD

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=239, Percent_Identity=30.5439330543933, Blast_Score=96, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6325425, Length=210, Percent_Identity=32.3809523809524, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 26987; Mature: 26856

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVDEPSDIAALEQRIEGTVAILRRVEAEYLPAVLASSFSAEDMVLLDLIRAHTPGIDA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCE
FTLDTGRLNAETYKLQQRVRERYGPVVRTYYPEAFEVEQVVASFGVNGFYHSLEARQACC
EEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
HARKVEPLRRALSGQRAWLTGMRRAQAATRSELPIEEHDPEQGLIKLNPLAEWQEADVWG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHH
YLRSHGVPYNKLYDQGYRSIGCAPCTRPVAAGEDIRAGRWWWEHPARRECGLHRSPQD
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHCCCCCCCCC
>Mature Secondary Structure 
AIVDEPSDIAALEQRIEGTVAILRRVEAEYLPAVLASSFSAEDMVLLDLIRAHTPGIDA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCE
FTLDTGRLNAETYKLQQRVRERYGPVVRTYYPEAFEVEQVVASFGVNGFYHSLEARQACC
EEECCCCCCHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
HARKVEPLRRALSGQRAWLTGMRRAQAATRSELPIEEHDPEQGLIKLNPLAEWQEADVWG
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHHH
YLRSHGVPYNKLYDQGYRSIGCAPCTRPVAAGEDIRAGRWWWEHPARRECGLHRSPQD
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]