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The map label for this gene is carA [H]

Identifier: 121998555

GI number: 121998555

Start: 1950714

End: 1951853

Strand: Reverse

Name: carA [H]

Synonym: Hhal_1776

Alternate gene names: 121998555

Gene position: 1951853-1950714 (Counterclockwise)

Preceding gene: 121998556

Following gene: 121998554

Centisome position: 72.87

GC content: 68.51

Gene sequence:

>1140_bases
TTGACCCGGCCAGCACTGCTCGTCCTCCAGGACGGTACGGTTTTCCACGGCGAGGCGGTGGGCGCCGACGGGGCCGTGAC
CGGCGAGGTGGTTTTCAACACCGCCATGACCGGTTATCAGGAGATCGCCACCGACCCTTCCTACGCCGGTCAGATCGTCA
CTCTGACCTATCCCCACATCGGCAATACCGGCATCAACAGTGTGGATCGCGAGGACGATCGCGCCCGGCTGGCTGGGCTG
GTGGTGCGTGATGTGCCGCCGCGGGCCAGCAACTGGCGTGCCGAGCAGGGACTGACAGCGTGGTTGCGCGAGCAGGGGGT
GGTGGCCATCTCCGGGATCGATACTCGCAAACTGACCCGCCGCCTCCGCGAAGGAGGCGCCCAGGGCGGCTGCCTGGCGG
CCGGCGAGTCCCTGGACGAGGCGTGGGCACTGGCTCAGGCGCAGGGGTATGGCGGCATGAGCGGGCGCGACCTGGCCGGA
GAGGCCGGTACCAAGACCCGCAGGCCCTGGCAGCGCGGGACCTGGACCCTGGATGACGGGTGTGCGGACGCTGCCGAGCG
TGGCGATGCCGGGCGCTACCACGTGGTGGCCTTTGATTACGGCATTAAACAGCAGATCCTGCGCCTGCTCGTCGATGCCG
ACTGCCGCGTCACCGTGGTGCCCGCGCGGACCGCCGCCGCGGATGTCCTCAAGCTGGAGCCGGACGGCCTGTTCTTCTCC
AACGGCCCGGGTGACCCGGAGCCCATGGAGTACGCCGTTGCCACCATCCGCGAGCTCCTCGACGAGCATCGCATCCCGAC
CTTCGGCATCTGTCTGGGCCATCAGCTGTTGGGGCTGGCCAGCGGGGCGCGGACCGAGAAGATGAAGTTCGGCCACCACG
GGGCCAACCACCCGGTGATCGATCTGGCCACCGGCCAAGTGCTGATCTCCAGCCAGAATCACGGCTTCGCCGTGGACGAG
GCCAGCCTGCCGGCCCACCTGAAGGCGACTCACCGTTCGTTGTTCGACGGCTCGCTGCAGGGCATCCGTCGAACCGACGT
GCCCGCCTTCAGCTTCCAGGGGCACCCGGAGGCGAGCCCGGGCCCCCACGACATGCGGCCGCTGTTCCAGCGCTTCGTCG
AGATGATGGAGCAGGGCTAA

Upstream 100 bases:

>100_bases
TCCATGGACGGGAGGGGCGAACCCTCCCGTTTTTTGCATGTCCGTACCCCGCCCGTGGCGTGCCCGGGCGGGCGTTCAGC
TCCAACCAGGGGAGGCTGCG

Downstream 100 bases:

>100_bases
GCGCCGCGCAGCTTCTTCTCTACAGCCGATCGCCGACCACTGGACCCCGAGCACTCTCGAATCATGCCGAAAAGAACTGA
CATCCAATCGATCCTGATCA

Product: carbamoyl-phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MTRPALLVLQDGTVFHGEAVGADGAVTGEVVFNTAMTGYQEIATDPSYAGQIVTLTYPHIGNTGINSVDREDDRARLAGL
VVRDVPPRASNWRAEQGLTAWLREQGVVAISGIDTRKLTRRLREGGAQGGCLAAGESLDEAWALAQAQGYGGMSGRDLAG
EAGTKTRRPWQRGTWTLDDGCADAAERGDAGRYHVVAFDYGIKQQILRLLVDADCRVTVVPARTAAADVLKLEPDGLFFS
NGPGDPEPMEYAVATIRELLDEHRIPTFGICLGHQLLGLASGARTEKMKFGHHGANHPVIDLATGQVLISSQNHGFAVDE
ASLPAHLKATHRSLFDGSLQGIRRTDVPAFSFQGHPEASPGPHDMRPLFQRFVEMMEQG

Sequences:

>Translated_379_residues
MTRPALLVLQDGTVFHGEAVGADGAVTGEVVFNTAMTGYQEIATDPSYAGQIVTLTYPHIGNTGINSVDREDDRARLAGL
VVRDVPPRASNWRAEQGLTAWLREQGVVAISGIDTRKLTRRLREGGAQGGCLAAGESLDEAWALAQAQGYGGMSGRDLAG
EAGTKTRRPWQRGTWTLDDGCADAAERGDAGRYHVVAFDYGIKQQILRLLVDADCRVTVVPARTAAADVLKLEPDGLFFS
NGPGDPEPMEYAVATIRELLDEHRIPTFGICLGHQLLGLASGARTEKMKFGHHGANHPVIDLATGQVLISSQNHGFAVDE
ASLPAHLKATHRSLFDGSLQGIRRTDVPAFSFQGHPEASPGPHDMRPLFQRFVEMMEQG
>Mature_378_residues
TRPALLVLQDGTVFHGEAVGADGAVTGEVVFNTAMTGYQEIATDPSYAGQIVTLTYPHIGNTGINSVDREDDRARLAGLV
VRDVPPRASNWRAEQGLTAWLREQGVVAISGIDTRKLTRRLREGGAQGGCLAAGESLDEAWALAQAQGYGGMSGRDLAGE
AGTKTRRPWQRGTWTLDDGCADAAERGDAGRYHVVAFDYGIKQQILRLLVDADCRVTVVPARTAAADVLKLEPDGLFFSN
GPGDPEPMEYAVATIRELLDEHRIPTFGICLGHQLLGLASGARTEKMKFGHHGANHPVIDLATGQVLISSQNHGFAVDEA
SLPAHLKATHRSLFDGSLQGIRRTDVPAFSFQGHPEASPGPHDMRPLFQRFVEMMEQG

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=385, Percent_Identity=39.4805194805195, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI169790915, Length=387, Percent_Identity=35.4005167958656, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI21361331, Length=387, Percent_Identity=35.4005167958656, Blast_Score=224, Evalue=2e-58,
Organism=Escherichia coli, GI1786215, Length=378, Percent_Identity=61.1111111111111, Blast_Score=489, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI193204318, Length=387, Percent_Identity=38.7596899224806, Blast_Score=233, Evalue=1e-61,
Organism=Saccharomyces cerevisiae, GI6324878, Length=388, Percent_Identity=38.9175257731959, Blast_Score=244, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6322331, Length=410, Percent_Identity=34.1463414634146, Blast_Score=234, Evalue=1e-62,
Organism=Drosophila melanogaster, GI45555749, Length=390, Percent_Identity=36.9230769230769, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24642586, Length=390, Percent_Identity=36.9230769230769, Blast_Score=222, Evalue=4e-58,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 40767; Mature: 40636

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPALLVLQDGTVFHGEAVGADGAVTGEVVFNTAMTGYQEIATDPSYAGQIVTLTYPHI
CCCCEEEEEECCCEEECCCCCCCCCEEHHHEEHHHHHHHHHHCCCCCCCCEEEEEEECCC
GNTGINSVDREDDRARLAGLVVRDVPPRASNWRAEQGLTAWLREQGVVAISGIDTRKLTR
CCCCCCCCCCCHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHH
RLREGGAQGGCLAAGESLDEAWALAQAQGYGGMSGRDLAGEAGTKTRRPWQRGTWTLDDG
HHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCC
CADAAERGDAGRYHVVAFDYGIKQQILRLLVDADCRVTVVPARTAAADVLKLEPDGLFFS
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCHHHEEEECCCCEEEC
NGPGDPEPMEYAVATIRELLDEHRIPTFGICLGHQLLGLASGARTEKMKFGHHGANHPVI
CCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCEE
DLATGQVLISSQNHGFAVDEASLPAHLKATHRSLFDGSLQGIRRTDVPAFSFQGHPEASP
EEECCEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCHHCCCCEEECCCCCCCCC
GPHDMRPLFQRFVEMMEQG
CCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRPALLVLQDGTVFHGEAVGADGAVTGEVVFNTAMTGYQEIATDPSYAGQIVTLTYPHI
CCCEEEEEECCCEEECCCCCCCCCEEHHHEEHHHHHHHHHHCCCCCCCCEEEEEEECCC
GNTGINSVDREDDRARLAGLVVRDVPPRASNWRAEQGLTAWLREQGVVAISGIDTRKLTR
CCCCCCCCCCCHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEECCCHHHHHH
RLREGGAQGGCLAAGESLDEAWALAQAQGYGGMSGRDLAGEAGTKTRRPWQRGTWTLDDG
HHHHCCCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCC
CADAAERGDAGRYHVVAFDYGIKQQILRLLVDADCRVTVVPARTAAADVLKLEPDGLFFS
HHHHHHCCCCCCEEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCHHHEEEECCCCEEEC
NGPGDPEPMEYAVATIRELLDEHRIPTFGICLGHQLLGLASGARTEKMKFGHHGANHPVI
CCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCEE
DLATGQVLISSQNHGFAVDEASLPAHLKATHRSLFDGSLQGIRRTDVPAFSFQGHPEASP
EEECCEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCHHCCCCEEECCCCCCCCC
GPHDMRPLFQRFVEMMEQG
CCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA