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The map label for this gene is nuoC

Identifier: 121998542

GI number: 121998542

Start: 1937742

End: 1938482

Strand: Reverse

Name: nuoC

Synonym: Hhal_1763

Alternate gene names: 121998542

Gene position: 1938482-1937742 (Counterclockwise)

Preceding gene: 121998543

Following gene: 121998541

Centisome position: 72.37

GC content: 66.4

Gene sequence:

>741_bases
ATGGCTGAGCCCGAGAGCCTCTTAGAGCAGCTCCGCGGCCATTTCGGTGGCCGTTTGACCGATTGCTGGCTCGAGCGCGG
CGAGGTGACGGCAGACGTCCGGCCTGCCGACCTGCTGGCGGTCATGACCGAACTGCGAGACGGTGCCGAGTGGCGCTTCG
AGCAGCTTTCCGATGTTGCCGGGGTTGATTACGCGGCTTACGGCCAGGACGAGTGGATCACCGAGTCGGCGACCGGCACG
GGCTTCAGCCGCGGCGTTACGGAGCCGGGCTTCGGGCGCTTGGGCCTGACCGGCATCTACGGTGTGCAGTCGATCGAGGA
GCAGACCGGTCGGCGCTTCGCGGCGGTCTATCAGCTGCTGTCGCTGACCCACAACCACCGTCTACGCGTGCGCTGCTTCG
CCGAAGACGACGACCTCCCGGTCCTGCCGTCGGTAACCGGCATCTGGCCCTGCGCCAACTGGGCCGAGCGGGAGGCCTTC
GACCTCTACGGCATTGTTTTCGAAGGCCATCCGGACCTGCGCCGCATCCTGACCGATTACGGCTTCGTGGGTCATCCGTT
CCGTAAGGACTTCCCGCTGATCGGCAACGTCGAGCCGCGCTACGACCCCGAAAAAGGCCGTGTGGTCTACGGCCCGGTGG
AGATCGAGCCGCGGGTGCTGGTGCCGCGGGTCATCCGTGAAGACAACCGCTATGCCGCACCGCAGAAGGCGGAAGGCACG
GAGGGACAAGCCGATGGCTGA

Upstream 100 bases:

>100_bases
ACCCGGCTGTCCGCCGACGGCCGAGGCGCTCTACTACGGCATTCTGCAGCTGCAGAACAAGATCCGCCGGACCAACACCA
TCGCACGTTGAGGGAAAGTC

Downstream 100 bases:

>100_bases
GTTCCAGAGCTACACCCTGAACTTCGGCCCGCAGCACCCGGCCGCCCACGGGGTGTTGCGCTTGGTGCTGGAGATGGAGG
GGGAGGCGGTGCGCCGTGCC

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MAEPESLLEQLRGHFGGRLTDCWLERGEVTADVRPADLLAVMTELRDGAEWRFEQLSDVAGVDYAAYGQDEWITESATGT
GFSRGVTEPGFGRLGLTGIYGVQSIEEQTGRRFAAVYQLLSLTHNHRLRVRCFAEDDDLPVLPSVTGIWPCANWAEREAF
DLYGIVFEGHPDLRRILTDYGFVGHPFRKDFPLIGNVEPRYDPEKGRVVYGPVEIEPRVLVPRVIREDNRYAAPQKAEGT
EGQADG

Sequences:

>Translated_246_residues
MAEPESLLEQLRGHFGGRLTDCWLERGEVTADVRPADLLAVMTELRDGAEWRFEQLSDVAGVDYAAYGQDEWITESATGT
GFSRGVTEPGFGRLGLTGIYGVQSIEEQTGRRFAAVYQLLSLTHNHRLRVRCFAEDDDLPVLPSVTGIWPCANWAEREAF
DLYGIVFEGHPDLRRILTDYGFVGHPFRKDFPLIGNVEPRYDPEKGRVVYGPVEIEPRVLVPRVIREDNRYAAPQKAEGT
EGQADG
>Mature_245_residues
AEPESLLEQLRGHFGGRLTDCWLERGEVTADVRPADLLAVMTELRDGAEWRFEQLSDVAGVDYAAYGQDEWITESATGTG
FSRGVTEPGFGRLGLTGIYGVQSIEEQTGRRFAAVYQLLSLTHNHRLRVRCFAEDDDLPVLPSVTGIWPCANWAEREAFD
LYGIVFEGHPDLRRILTDYGFVGHPFRKDFPLIGNVEPRYDPEKGRVVYGPVEIEPRVLVPRVIREDNRYAAPQKAEGTE
GQADG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=189, Percent_Identity=38.0952380952381, Blast_Score=122, Evalue=3e-28,
Organism=Escherichia coli, GI145693162, Length=80, Percent_Identity=45, Blast_Score=82, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71990788, Length=104, Percent_Identity=53.8461538461538, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI32563621, Length=104, Percent_Identity=53.8461538461538, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI24656494, Length=222, Percent_Identity=34.6846846846847, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_HALHL (A1WXW5)

Other databases:

- EMBL:   CP000544
- RefSeq:   YP_001003329.1
- ProteinModelPortal:   A1WXW5
- SMR:   A1WXW5
- STRING:   A1WXW5
- GeneID:   4711082
- GenomeReviews:   CP000544_GR
- KEGG:   hha:Hhal_1763
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   WITESAT
- ProtClustDB:   CLSK727525
- BioCyc:   HHAL349124:HHAL_1763-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 27570; Mature: 27439

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEPESLLEQLRGHFGGRLTDCWLERGEVTADVRPADLLAVMTELRDGAEWRFEQLSDVA
CCCHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHC
GVDYAAYGQDEWITESATGTGFSRGVTEPGFGRLGLTGIYGVQSIEEQTGRRFAAVYQLL
CCCEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLTHNHRLRVRCFAEDDDLPVLPSVTGIWPCANWAEREAFDLYGIVFEGHPDLRRILTDY
HHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCEEEEEEEECCCHHHHHHHHHC
GFVGHPFRKDFPLIGNVEPRYDPEKGRVVYGPVEIEPRVLVPRVIREDNRYAAPQKAEGT
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEECHHHHHCCCCCCCCCCCCCC
EGQADG
CCCCCC
>Mature Secondary Structure 
AEPESLLEQLRGHFGGRLTDCWLERGEVTADVRPADLLAVMTELRDGAEWRFEQLSDVA
CCHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHC
GVDYAAYGQDEWITESATGTGFSRGVTEPGFGRLGLTGIYGVQSIEEQTGRRFAAVYQLL
CCCEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SLTHNHRLRVRCFAEDDDLPVLPSVTGIWPCANWAEREAFDLYGIVFEGHPDLRRILTDY
HHHCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHCCEEEEEEEECCCHHHHHHHHHC
GFVGHPFRKDFPLIGNVEPRYDPEKGRVVYGPVEIEPRVLVPRVIREDNRYAAPQKAEGT
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEECHHHHHCCCCCCCCCCCCCC
EGQADG
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA