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The map label for this gene is zur [H]

Identifier: 121998508

GI number: 121998508

Start: 1895718

End: 1896212

Strand: Reverse

Name: zur [H]

Synonym: Hhal_1729

Alternate gene names: 121998508

Gene position: 1896212-1895718 (Counterclockwise)

Preceding gene: 121998510

Following gene: 121998507

Centisome position: 70.8

GC content: 65.05

Gene sequence:

>495_bases
ATGGCCCGCTTACACCGCTCGCTGGTAACCGGATTCCCCAGCGAAGACCACGACCACGACGTCTGCCGCGAGACGGTCCT
GGCGACCGCCGAGGTCATTTGTCGCCGTCGCGGCATGCGCTTTACGCGGCTGCGCCGCCGGGTGTTGGAGCTGATCTGGG
ATGAGCACCGTCCGGTCAAGGCGTACGAGTTGCTGGATCGTCTGCGCGGCGAGCGGGCCGGCGCGGCGCCGCCCACCGTC
TACCGCACCCTCGATTTCCTGTTGCAGGAAGGGCTGATCCATCGTGTGGAATCCCTGAACGCCTATGTCGGTTGCGGCAA
ACCCGGGCACGTACACCCGGTTCAGCTGTTGGTCTGTCGCTCCTGTGCGGCGGTGGCCGAACTTGCCGACGATGATGTGG
CGCGTTTGCTCCAGCACAAGGCCGGGCAGATGGGGTTCCAGACCGATTCCGCAGTGGTGGAGCTTGAAGGTGTATGTCCC
CAGTGCAGCCGTTAG

Upstream 100 bases:

>100_bases
GAGGAGTGCGGGAAGCGCTCGCATGGGTCGAATCCCCGGGACTTTTCACGGCATCGTTATGTTATACAATACCAAAATGC
GCAACAACGGCGAGCACCCC

Downstream 100 bases:

>100_bases
CTGGTAGGCAGGCCGCTGACGATCCGCTGATCCGTCTCCAGGAGGTGGCCGTGACCTTCGGCGGGCGATCCATACTCCAG
GATGTCCGCCTGGAGGTGGT

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Zinc uptake regulator [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MARLHRSLVTGFPSEDHDHDVCRETVLATAEVICRRRGMRFTRLRRRVLELIWDEHRPVKAYELLDRLRGERAGAAPPTV
YRTLDFLLQEGLIHRVESLNAYVGCGKPGHVHPVQLLVCRSCAAVAELADDDVARLLQHKAGQMGFQTDSAVVELEGVCP
QCSR

Sequences:

>Translated_164_residues
MARLHRSLVTGFPSEDHDHDVCRETVLATAEVICRRRGMRFTRLRRRVLELIWDEHRPVKAYELLDRLRGERAGAAPPTV
YRTLDFLLQEGLIHRVESLNAYVGCGKPGHVHPVQLLVCRSCAAVAELADDDVARLLQHKAGQMGFQTDSAVVELEGVCP
QCSR
>Mature_163_residues
ARLHRSLVTGFPSEDHDHDVCRETVLATAEVICRRRGMRFTRLRRRVLELIWDEHRPVKAYELLDRLRGERAGAAPPTVY
RTLDFLLQEGLIHRVESLNAYVGCGKPGHVHPVQLLVCRSCAAVAELADDDVARLLQHKAGQMGFQTDSAVVELEGVCPQ
CSR

Specific function: Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes (znuACB) [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI87082363, Length=142, Percent_Identity=40.8450704225352, Blast_Score=106, Evalue=9e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18479; Mature: 18347

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS00196 COPPER_BLUE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLHRSLVTGFPSEDHDHDVCRETVLATAEVICRRRGMRFTRLRRRVLELIWDEHRPVK
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCH
AYELLDRLRGERAGAAPPTVYRTLDFLLQEGLIHRVESLNAYVGCGKPGHVHPVQLLVCR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
SCAAVAELADDDVARLLQHKAGQMGFQTDSAVVELEGVCPQCSR
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCCC
>Mature Secondary Structure 
ARLHRSLVTGFPSEDHDHDVCRETVLATAEVICRRRGMRFTRLRRRVLELIWDEHRPVK
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCH
AYELLDRLRGERAGAAPPTVYRTLDFLLQEGLIHRVESLNAYVGCGKPGHVHPVQLLVCR
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
SCAAVAELADDDVARLLQHKAGQMGFQTDSAVVELEGVCPQCSR
HHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 9680209 [H]