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The map label for this gene is 121998504

Identifier: 121998504

GI number: 121998504

Start: 1892127

End: 1893653

Strand: Reverse

Name: 121998504

Synonym: Hhal_1725

Alternate gene names: NA

Gene position: 1893653-1892127 (Counterclockwise)

Preceding gene: 121998506

Following gene: 121998503

Centisome position: 70.7

GC content: 67.52

Gene sequence:

>1527_bases
GTGACGGATCGGATCCCTGACCTGGAGGCCCACCGGGCCCTGGCCGAGGCACTCCAGGCCCCGGAGTGCTACCCGTGGCC
GGTGGACACTGTCGAGTGTATCGAGACCCACATCTCCACGGTGCTGCTCGCCGGGGCGTACGTGGTCAAGCTCAAGAAAC
CGCTGGACCTCGGCTTCCTGGACTTCTCCAGCCTGGAGCGGCGACGCTACTTCTGCGACGAAGAGGTTCGCCTCAACGGC
CGCTTGGCTCCGCAGATCTACCTGCGCCGAGTGGCAATCGCCGGTCCGGCGACGGAGCCGCGCATCGACGGCGAAGGGGA
CGTGCTGGAGTACGCGGTGCTCATGCGCCGCTTCCCCGAGAATGAGCTCATGAGCCGTCTGCTGCGCGAGGGGCGTCTGC
CCCATGGAGCCGTCGAGCGCCTGGCTGAGACTGTGGCGCGGTTCCATGCCGGGCTGCCGGCCGCCGGGGAGGATAGTGAA
TACGGGTCGCCGGAGGCCGTGGCCGATCCCATGCGTGACAACTTCCGCGCCCTGGAGACCCAGTCCGCGGCCGCCTCGAT
GCGCGGCGAACTGCGTGCCCTGGAGCGCTGGACCGAGGCACAGCTGCAGCGGCTGGAGCCGCTGATCCGCCGGCGACGCG
CCGAGGGCGCGGTGCGTGAATGCCACGGGGACCTGCACTTGGGCAATGTCGCCTGGCATGAGGACGACCTGATCATCTTT
GATGGCATCGAGTTCAATCCGGCACTGCGCTGGATCGACACGGCCAGCGAGGTCGCCTTCACCGTTATGGATCTGGATTT
TGAAGGGGCCCGTCGGCTTCGCCACTGCTTCCTGGACCGCTACCTGGAGCAGAGTGGCGACTACCAGGCGCTGCCGCTGC
TGCCCCTGTACGCCGTGTATCGGGCCCTGGTGCGGGCCAAGATCAACGGCCACGAGGTCGAACAGGGGGGTGGCAGTGCA
GCCCAGGAGGCGCTCTGCGACCACGTCCAACTGGCCAAGAGCTATACGGTGGCGCAGGTGCCGGAGTTGGTCATTACCTA
CGGGTTATCGGGATCCGGCAAGAGCGTACGCGCCCGCCGACTGGTCGAGGAGCGCGGGTTTATCCGGCTGCGATCGGATG
TCGAGCGCAAGCGGCTGTTCGGTTTGGAGCCCCGCGCGCGCTCGGACTCGACCCTGGATAGCGGGCTCTATTCGCCGGAG
GCAACGTGGCGGACTTACGAACGACTGCAGGAGCAGGCCGAGGGCGCCCTGGAAGCCGGCTTTTCGGTGGTGGTGGATGC
CGCCTTCCTCAAGGCCGAGCGACGCCGGCCGTTCCTGGAGCTGGCTGCGCGCACCGGATGTCGATTTCGGATCCTGCATG
TTCGGGCCGACGAACAGACCCTGCGGGAACGCCTGCGCAAGCGGCTGGCCGAGGGGCGCGATCCCTCCGAGGCCGATGAG
ACGGTGCTCGATGCTCAGCTGCGTACAGCGCAACCGCCGTCCGGCGAGGAAGCGGCTTTCGTCGAAACCGTCGACGCGGA
CGGGTAA

Upstream 100 bases:

>100_bases
GTTTCATTCTGTTCGATCATAGGGGAGAGGATACAGGCTGGAGCCGGGCGGCTGAAGCCGGCAAGCTGGGCAGGTCGAGC
AACAGAAGGAGTGCGCAGCC

Downstream 100 bases:

>100_bases
GATAGCCGGCCTTGCCTTGTGCCGGATCGAGGAGAGCTATGTCAGGAGTCCCCAGCCAACCCGGTGAGCCGGTGACCGAT
GTCGCGCAGCTGGCAGAGCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MTDRIPDLEAHRALAEALQAPECYPWPVDTVECIETHISTVLLAGAYVVKLKKPLDLGFLDFSSLERRRYFCDEEVRLNG
RLAPQIYLRRVAIAGPATEPRIDGEGDVLEYAVLMRRFPENELMSRLLREGRLPHGAVERLAETVARFHAGLPAAGEDSE
YGSPEAVADPMRDNFRALETQSAAASMRGELRALERWTEAQLQRLEPLIRRRRAEGAVRECHGDLHLGNVAWHEDDLIIF
DGIEFNPALRWIDTASEVAFTVMDLDFEGARRLRHCFLDRYLEQSGDYQALPLLPLYAVYRALVRAKINGHEVEQGGGSA
AQEALCDHVQLAKSYTVAQVPELVITYGLSGSGKSVRARRLVEERGFIRLRSDVERKRLFGLEPRARSDSTLDSGLYSPE
ATWRTYERLQEQAEGALEAGFSVVVDAAFLKAERRRPFLELAARTGCRFRILHVRADEQTLRERLRKRLAEGRDPSEADE
TVLDAQLRTAQPPSGEEAAFVETVDADG

Sequences:

>Translated_508_residues
MTDRIPDLEAHRALAEALQAPECYPWPVDTVECIETHISTVLLAGAYVVKLKKPLDLGFLDFSSLERRRYFCDEEVRLNG
RLAPQIYLRRVAIAGPATEPRIDGEGDVLEYAVLMRRFPENELMSRLLREGRLPHGAVERLAETVARFHAGLPAAGEDSE
YGSPEAVADPMRDNFRALETQSAAASMRGELRALERWTEAQLQRLEPLIRRRRAEGAVRECHGDLHLGNVAWHEDDLIIF
DGIEFNPALRWIDTASEVAFTVMDLDFEGARRLRHCFLDRYLEQSGDYQALPLLPLYAVYRALVRAKINGHEVEQGGGSA
AQEALCDHVQLAKSYTVAQVPELVITYGLSGSGKSVRARRLVEERGFIRLRSDVERKRLFGLEPRARSDSTLDSGLYSPE
ATWRTYERLQEQAEGALEAGFSVVVDAAFLKAERRRPFLELAARTGCRFRILHVRADEQTLRERLRKRLAEGRDPSEADE
TVLDAQLRTAQPPSGEEAAFVETVDADG
>Mature_507_residues
TDRIPDLEAHRALAEALQAPECYPWPVDTVECIETHISTVLLAGAYVVKLKKPLDLGFLDFSSLERRRYFCDEEVRLNGR
LAPQIYLRRVAIAGPATEPRIDGEGDVLEYAVLMRRFPENELMSRLLREGRLPHGAVERLAETVARFHAGLPAAGEDSEY
GSPEAVADPMRDNFRALETQSAAASMRGELRALERWTEAQLQRLEPLIRRRRAEGAVRECHGDLHLGNVAWHEDDLIIFD
GIEFNPALRWIDTASEVAFTVMDLDFEGARRLRHCFLDRYLEQSGDYQALPLLPLYAVYRALVRAKINGHEVEQGGGSAA
QEALCDHVQLAKSYTVAQVPELVITYGLSGSGKSVRARRLVEERGFIRLRSDVERKRLFGLEPRARSDSTLDSGLYSPEA
TWRTYERLQEQAEGALEAGFSVVVDAAFLKAERRRPFLELAARTGCRFRILHVRADEQTLRERLRKRLAEGRDPSEADET
VLDAQLRTAQPPSGEEAAFVETVDADG

Specific function: Some isolated peptides of this protein are able to bind to human U937 monocytoblastic and A549 epithelial cell lines [H]

COG id: COG2187

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR010488 [H]

Pfam domain/function: PF06414 Zeta_toxin [H]

EC number: NA

Molecular weight: Translated: 57203; Mature: 57072

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRIPDLEAHRALAEALQAPECYPWPVDTVECIETHISTVLLAGAYVVKLKKPLDLGFL
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
DFSSLERRRYFCDEEVRLNGRLAPQIYLRRVAIAGPATEPRIDGEGDVLEYAVLMRRFPE
CHHHHHHHHHCCCCHHEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCH
NELMSRLLREGRLPHGAVERLAETVARFHAGLPAAGEDSEYGSPEAVADPMRDNFRALET
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QSAAASMRGELRALERWTEAQLQRLEPLIRRRRAEGAVRECHGDLHLGNVAWHEDDLIIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEECCEEEECCCEEEE
DGIEFNPALRWIDTASEVAFTVMDLDFEGARRLRHCFLDRYLEQSGDYQALPLLPLYAVY
CCCCCCCHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
RALVRAKINGHEVEQGGGSAAQEALCDHVQLAKSYTVAQVPELVITYGLSGSGKSVRARR
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCHHHEEECCCCCCCHHHHHH
LVEERGFIRLRSDVERKRLFGLEPRARSDSTLDSGLYSPEATWRTYERLQEQAEGALEAG
HHHHCCCEEEHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
FSVVVDAAFLKAERRRPFLELAARTGCRFRILHVRADEQTLRERLRKRLAEGRDPSEADE
HHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCHHHH
TVLDAQLRTAQPPSGEEAAFVETVDADG
HHHHHHHHCCCCCCCCCCEEEEECCCCC
>Mature Secondary Structure 
TDRIPDLEAHRALAEALQAPECYPWPVDTVECIETHISTVLLAGAYVVKLKKPLDLGFL
CCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCC
DFSSLERRRYFCDEEVRLNGRLAPQIYLRRVAIAGPATEPRIDGEGDVLEYAVLMRRFPE
CHHHHHHHHHCCCCHHEECCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCH
NELMSRLLREGRLPHGAVERLAETVARFHAGLPAAGEDSEYGSPEAVADPMRDNFRALET
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
QSAAASMRGELRALERWTEAQLQRLEPLIRRRRAEGAVRECHGDLHLGNVAWHEDDLIIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEECCEEEECCCEEEE
DGIEFNPALRWIDTASEVAFTVMDLDFEGARRLRHCFLDRYLEQSGDYQALPLLPLYAVY
CCCCCCCHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
RALVRAKINGHEVEQGGGSAAQEALCDHVQLAKSYTVAQVPELVITYGLSGSGKSVRARR
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCHHHEEECCCCCCCHHHHHH
LVEERGFIRLRSDVERKRLFGLEPRARSDSTLDSGLYSPEATWRTYERLQEQAEGALEAG
HHHHCCCEEEHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
FSVVVDAAFLKAERRRPFLELAARTGCRFRILHVRADEQTLRERLRKRLAEGRDPSEADE
HHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCCHHHH
TVLDAQLRTAQPPSGEEAAFVETVDADG
HHHHHHHHCCCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]