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The map label for this gene is xerD [H]

Identifier: 121998438

GI number: 121998438

Start: 1813408

End: 1814172

Strand: Reverse

Name: xerD [H]

Synonym: Hhal_1659

Alternate gene names: 121998438

Gene position: 1814172-1813408 (Counterclockwise)

Preceding gene: 121998439

Following gene: 121998435

Centisome position: 67.73

GC content: 69.67

Gene sequence:

>765_bases
GTGGACGGGCTTGTCGCCGCGGGTCGCGGCGATGTCTTCGCCTACCTGGCCGAGCGGGTCGCTGCGGGGGCGCGGCCGCG
CACAACGGCGCGTCTGCTGAGCAGCCTCCGACGCTTCTACCGTCGGCTGGTATCCACGGGGGAGCGCAGCGACGATCCCA
CCGCCGAAGTCGAGGCGCCCCGTCTCGGCCAGCCCCTGCCCGGCGCGCTGACCGAACGTCAGGTTGAGGCCCTGCTTGCG
GCACCGGATACCGGTGATCCGCTGGGGCTGCGGGACCGGTGCCTGCTCGAGGTGCTCTACGCCACCGGGCTTCGCGTCTC
GGAGTTGGTGGCCTTGCGCGTGGATGGAGTGAGTCTGCGTCAGGGGGTCGTGCGAGTGATCGGCAAGGGCGATCGGGAAC
GCCTGGTCCCGCTTGGCGAAGAGGCTGTCGACTGGGTGCGTCGATACCTTGAGGAGGTGAGGCCGCTGCTGCTCGACGGT
CGAGCCGCGGAGGCGCTATTCGTGACGCGCCGTGGTGAGGGGCTGACGCGTCAGGCGTTCTGGTACCGGGTCAAGCGCTA
CGCGGCCGCGGCGGGGATTGACCCGGCGATCTCGCCGCATACGCTGCGCCACTCGTTCGCCACCCACCTGATCAACCACG
GGGCGGATCTGCGTGTTGTACAGATGCTGCTGGGCCACGCCGATCTGTCCACCACCCAGATCTATACCCACGTGGCCCGG
CAGCGTCTGCAGCAACTTCACGCCGCGCACCATCCGCGCGGCTGA

Upstream 100 bases:

>100_bases
TCTCGATGCCCTGTGGGCCGAACAGGGCCTGTCTGCAGCGACCCTCTCGGCCTATCGCTCGGACCTGGAGGGGTTCGCGG
CGTTCCTTCAGGGGCGCGGC

Downstream 100 bases:

>100_bases
TATCTGCCGGAGGCTCAGCGCTCTAGGTGCTGGAGCTTGTCCGGCTTGCCGTCCCACTCCTCGGCGTCCGGCGGCGGATC
CTTCTTCTCGGTGATGAGTG

Product: tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 254; Mature: 254

Protein sequence:

>254_residues
MDGLVAAGRGDVFAYLAERVAAGARPRTTARLLSSLRRFYRRLVSTGERSDDPTAEVEAPRLGQPLPGALTERQVEALLA
APDTGDPLGLRDRCLLEVLYATGLRVSELVALRVDGVSLRQGVVRVIGKGDRERLVPLGEEAVDWVRRYLEEVRPLLLDG
RAAEALFVTRRGEGLTRQAFWYRVKRYAAAAGIDPAISPHTLRHSFATHLINHGADLRVVQMLLGHADLSTTQIYTHVAR
QRLQQLHAAHHPRG

Sequences:

>Translated_254_residues
MDGLVAAGRGDVFAYLAERVAAGARPRTTARLLSSLRRFYRRLVSTGERSDDPTAEVEAPRLGQPLPGALTERQVEALLA
APDTGDPLGLRDRCLLEVLYATGLRVSELVALRVDGVSLRQGVVRVIGKGDRERLVPLGEEAVDWVRRYLEEVRPLLLDG
RAAEALFVTRRGEGLTRQAFWYRVKRYAAAAGIDPAISPHTLRHSFATHLINHGADLRVVQMLLGHADLSTTQIYTHVAR
QRLQQLHAAHHPRG
>Mature_254_residues
MDGLVAAGRGDVFAYLAERVAAGARPRTTARLLSSLRRFYRRLVSTGERSDDPTAEVEAPRLGQPLPGALTERQVEALLA
APDTGDPLGLRDRCLLEVLYATGLRVSELVALRVDGVSLRQGVVRVIGKGDRERLVPLGEEAVDWVRRYLEEVRPLLLDG
RAAEALFVTRRGEGLTRQAFWYRVKRYAAAAGIDPAISPHTLRHSFATHLINHGADLRVVQMLLGHADLSTTQIYTHVAR
QRLQQLHAAHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=252, Percent_Identity=60.7142857142857, Blast_Score=304, Evalue=4e-84,
Organism=Escherichia coli, GI1790244, Length=258, Percent_Identity=40.6976744186046, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1790767, Length=169, Percent_Identity=32.5443786982249, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1790768, Length=168, Percent_Identity=32.1428571428571, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 28065; Mature: 28065

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGLVAAGRGDVFAYLAERVAAGARPRTTARLLSSLRRFYRRLVSTGERSDDPTAEVEAP
CCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RLGQPLPGALTERQVEALLAAPDTGDPLGLRDRCLLEVLYATGLRVSELVALRVDGVSLR
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHH
QGVVRVIGKGDRERLVPLGEEAVDWVRRYLEEVRPLLLDGRAAEALFVTRRGEGLTRQAF
HHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCHHHHH
WYRVKRYAAAAGIDPAISPHTLRHSFATHLINHGADLRVVQMLLGHADLSTTQIYTHVAR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHH
QRLQQLHAAHHPRG
HHHHHHHHHCCCCC
>Mature Secondary Structure
MDGLVAAGRGDVFAYLAERVAAGARPRTTARLLSSLRRFYRRLVSTGERSDDPTAEVEAP
CCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RLGQPLPGALTERQVEALLAAPDTGDPLGLRDRCLLEVLYATGLRVSELVALRVDGVSLR
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHH
QGVVRVIGKGDRERLVPLGEEAVDWVRRYLEEVRPLLLDGRAAEALFVTRRGEGLTRQAF
HHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEECCCCCHHHHH
WYRVKRYAAAAGIDPAISPHTLRHSFATHLINHGADLRVVQMLLGHADLSTTQIYTHVAR
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHH
QRLQQLHAAHHPRG
HHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]