Click here to switch to the map view.

The map label for this gene is frdD [H]

Identifier: 121998229

GI number: 121998229

Start: 1560297

End: 1560647

Strand: Reverse

Name: frdD [H]

Synonym: Hhal_1447

Alternate gene names: 121998229

Gene position: 1560647-1560297 (Counterclockwise)

Preceding gene: 121998230

Following gene: 121998226

Centisome position: 58.27

GC content: 72.93

Gene sequence:

>351_bases
ATGAGACGTTCCCACGAACCGCCGCTGTGGCTGCTCTTCGGCGCCGGGGGGCTGCTGGCGGCGCTGCTTGGTCCGGCACT
GATCCTGTTGACCGGCATCGTGATGCCCGTCGCCGCGGAGCATGGGGTCGAGCTGCTGGGCTACCAGTCGATGCGGGAAC
TGCTGGCCCGGCCGGTGGTGGGTCTGGCGGTGGCTCTGGGGCTCGGGGTGGTGCTCTGCCACGCGGCCCACCGGATCTAC
CACACCCTGCGCGACCTCGGGGTCCGGGCCGGACGGGGTACCTGGTGGGCGTGTTACGGCAGCGCCGGCGCCGCGGCGCT
GGTCGCCGTGGGCGCCGTCCTCACCCTGTAG

Upstream 100 bases:

>100_bases
GCGGCTACCGGCCCACGGACCGAATGCTGGTATGGGGCGGCTGGGTGCTCTCGGCCGTCCTCTCGGGTGGCGTCTGCCTT
TACATCCTCGGAGGGGCTGG

Downstream 100 bases:

>100_bases
TGGGCTACGGCGGATCATTGGACGCTTGCGCGCTGCAGCAGCGCAGGTGGGGATGGGGCTCCGGGCGCGCCCACAGGAAA
CCCTGGGCGACCCGGCACCC

Product: fumarate reductase subunit D

Products: fumarate; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MRRSHEPPLWLLFGAGGLLAALLGPALILLTGIVMPVAAEHGVELLGYQSMRELLARPVVGLAVALGLGVVLCHAAHRIY
HTLRDLGVRAGRGTWWACYGSAGAAALVAVGAVLTL

Sequences:

>Translated_116_residues
MRRSHEPPLWLLFGAGGLLAALLGPALILLTGIVMPVAAEHGVELLGYQSMRELLARPVVGLAVALGLGVVLCHAAHRIY
HTLRDLGVRAGRGTWWACYGSAGAAALVAVGAVLTL
>Mature_116_residues
MRRSHEPPLWLLFGAGGLLAALLGPALILLTGIVMPVAAEHGVELLGYQSMRELLARPVVGLAVALGLGVVLCHAAHRIY
HTLRDLGVRAGRGTWWACYGSAGAAALVAVGAVLTL

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane [H]

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family [H]

Homologues:

Organism=Escherichia coli, GI1790594, Length=119, Percent_Identity=33.6134453781513, Blast_Score=59, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003418
- ProDom:   PD015693 [H]

Pfam domain/function: PF02313 Fumarate_red_D [H]

EC number: 1.3.1.6

Molecular weight: Translated: 12055; Mature: 12055

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSHEPPLWLLFGAGGLLAALLGPALILLTGIVMPVAAEHGVELLGYQSMRELLARPVV
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GLAVALGLGVVLCHAAHRIYHTLRDLGVRAGRGTWWACYGSAGAAALVAVGAVLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRSHEPPLWLLFGAGGLLAALLGPALILLTGIVMPVAAEHGVELLGYQSMRELLARPVV
CCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
GLAVALGLGVVLCHAAHRIYHTLRDLGVRAGRGTWWACYGSAGAAALVAVGAVLTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; NAD+

Specific reaction: succinate + NAD+ = fumarate + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA