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The map label for this gene is tmcA [H]

Identifier: 121998169

GI number: 121998169

Start: 1494813

End: 1496906

Strand: Reverse

Name: tmcA [H]

Synonym: Hhal_1387

Alternate gene names: 121998169

Gene position: 1496906-1494813 (Counterclockwise)

Preceding gene: 121998170

Following gene: 121998167

Centisome position: 55.89

GC content: 74.64

Gene sequence:

>2094_bases
GTGAGCCGCCGCACGGCGGTGCTCGCTGGACCGCCGCAGTGGGGGCGCGACCTGGCCGCCGGGCAGCTGCCCGATAACGC
CCGGATCTGTTGGATCGGCGAACCGCCGGCGGCGGGCCTGCCGGAGGCTGTCACCCGGCTGGCGGCGCGGGATGGTCGCC
GGGTGCTCGGACGCACGGTGGATATCCTGGTCTACGATGCCCACGCCGGGCTCGACGCCGACGCCCTGGGCGCCGCGGCC
GGTTCGCTGCGCGGTGGAGGCCTGCTGGTCCTGCTGACGCCGGCGTGGGCCGAGTGGCCGACCCGCCCCGATCCGCTACT
CGGCCGGCTCATCCCGGCCGGACATGGGCGGGACGAGGCCGGTCAGCGCTTTCTGCGGCGCCTGATGGCCGAGCTTGAGC
AGGATCCGAGCGTCACCCTCTGGACCCCGGAGCAGCCGCCGCCGGCACTCGAGCCGACGCCGCCGGCCGCGCCGGGCGGG
GCCTACGCCTACGGCTGCCTCAGTGCCGATCAAAAGACCGCTGTGGAGGCGGTGATGCACGTAGTGACCGGCCACCGCCG
CCGCCCGGCGGTGCTGACCGCCGATCGTGGCCGGGGCAAGTCCGCGGCCCTGGGCATCGCCGTGGGCGAACTGCTGCGTC
AGCGGCGGGTGCAGCGGGTGGTGGTCACAGCGCCGACGATCCACGCCGCCGAGGGTCTGCTCGACCACGCGGCCGAGCGT
TGCGGCGGGGAGCGGGTCGAGCGTCGGCGGCTGCGCTGCCACGGTGCCGAGGTGGTCTATCGCGAACCGGAGGCGCTGCG
CGAACGCCCGGAGAGCGGCGATCTGCTGGCGGTGGACGAGGCCGCGGGGCTGCCCGTGGATCTCCTTGCCCAGTTGCTCG
AGCACGCCGGGCGGATCGCGTTCGCCACCACCGTGCACGGCTACGAGGGCAGCGGTCGCGGCTTCGATCTGCGCTTCCGG
GCCATCCTCGATGCCGAGACACCCGGCTGGCAGGCGGTCCGTCTTGAGGCGCCGATCCGTTGGGATCGCAACGACCCGCT
GGAGGCGTGGTTGGGGCGGGTCCTCTGTCTGGACGCGGAGCCGGCCACCCTGGAGGACGGCGGCGGCTCAGCGGCGGAGA
TCGTCCCCGTCACGCAGGATGCGCTGGCGCAGGAGGAGCGCCGGCTGCGTCAGGCCTTCGGGTTGCTGGTGGCCGCCCAC
TACCGCACCCGCCCCTTCGACCTCCATCAGCTCCTCGATGGTCCGCGCCGCCACCTCTTCCTGGCGGAGGAGGCGGGTGC
GGTGGTCGGGGTGGTGGTGGCCGCTGAGGAGGGCGGGCTGGACCCGGAAACGGCCCACGAAGTGTGGGCGGAGCGGCGTC
GCCCCCATGGCCACTTGTTGCCGCAGGCGCTGGCCACCCACGCCGGGATCGAAATGGCCCCCACCGGCCGTGCCTTGCGC
ATCCAGCGCATCGCCGTGCATCCGCGGCGACGGGGGCACGGCATCGGTGCCGCACTGGTGGCTGCGGTGACCGAGCGGGC
CCGCGGGGCCGGCTGTGCCCTGGTAGGGACCAGCTTCGGGGCGACCCCGGGGCTGATCGGCTTCTGGCGGGCCTGCGGAA
TGCACGCCGTGGCGGTGGGAGCCCGGCGGGACGCCGCCAGCGGCGAGCACTCGGCGTTGATGGCGCGGGGGCTGGATGAG
CAGGGGGTTGCCTGGGTGCGCCAGGCCGGATTCCGGTTGGGTGCCGGAGCCCCCGCGCTCCTCGGGGAGCCCCTGGCGCG
TATGGAGCCGCAGGTCGTGCTGGCGGTGCTGCGTGCGGCGCAGGGTGCCGAGCCGCCGGTGCTGAGCGATTGGCAGCGGC
AGGAGCTGGTCGGGTTTGCCCACAGCCTGCGCGGCTACGCAGCAGCCCTGCCGGCGTTGTGGGTCCTGGCCGAGGTGGTG
CTGATGGATCCGCACGGGTCGCGCGGGCGCATGGCGCATTGCGAGGCGGCCTTCATCGGCAAGGTCCTGCAGCACCGCCC
GTGGGCGGATACGGCGCAGCGTCTGGGAGTCCCGGGGCGGCGCCCGGCGCTCGCGGCGCTGCGCCAGGCGGTGGCCGATT
CACTCCCGGAATGA

Upstream 100 bases:

>100_bases
GGATGCTGGAGGAGTACCGGATCTCGCTGTTCGCCCAGGACGTGGGTGCGCGGGAGAAGGTCTCGGAAAAGCGCCTCCAG
GAACTCTGGCGGGAGGTGGC

Downstream 100 bases:

>100_bases
CCGGCCGAGGGCCTCCATGCGCGCCCGCTGCTCGTACTCCTGCTGGCGCTCGATCTCCTCGGGGTCGTCCGGGTTCGCGG
GGCAGCGGCCCGAATGGACC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MSRRTAVLAGPPQWGRDLAAGQLPDNARICWIGEPPAAGLPEAVTRLAARDGRRVLGRTVDILVYDAHAGLDADALGAAA
GSLRGGGLLVLLTPAWAEWPTRPDPLLGRLIPAGHGRDEAGQRFLRRLMAELEQDPSVTLWTPEQPPPALEPTPPAAPGG
AYAYGCLSADQKTAVEAVMHVVTGHRRRPAVLTADRGRGKSAALGIAVGELLRQRRVQRVVVTAPTIHAAEGLLDHAAER
CGGERVERRRLRCHGAEVVYREPEALRERPESGDLLAVDEAAGLPVDLLAQLLEHAGRIAFATTVHGYEGSGRGFDLRFR
AILDAETPGWQAVRLEAPIRWDRNDPLEAWLGRVLCLDAEPATLEDGGGSAAEIVPVTQDALAQEERRLRQAFGLLVAAH
YRTRPFDLHQLLDGPRRHLFLAEEAGAVVGVVVAAEEGGLDPETAHEVWAERRRPHGHLLPQALATHAGIEMAPTGRALR
IQRIAVHPRRRGHGIGAALVAAVTERARGAGCALVGTSFGATPGLIGFWRACGMHAVAVGARRDAASGEHSALMARGLDE
QGVAWVRQAGFRLGAGAPALLGEPLARMEPQVVLAVLRAAQGAEPPVLSDWQRQELVGFAHSLRGYAAALPALWVLAEVV
LMDPHGSRGRMAHCEAAFIGKVLQHRPWADTAQRLGVPGRRPALAALRQAVADSLPE

Sequences:

>Translated_697_residues
MSRRTAVLAGPPQWGRDLAAGQLPDNARICWIGEPPAAGLPEAVTRLAARDGRRVLGRTVDILVYDAHAGLDADALGAAA
GSLRGGGLLVLLTPAWAEWPTRPDPLLGRLIPAGHGRDEAGQRFLRRLMAELEQDPSVTLWTPEQPPPALEPTPPAAPGG
AYAYGCLSADQKTAVEAVMHVVTGHRRRPAVLTADRGRGKSAALGIAVGELLRQRRVQRVVVTAPTIHAAEGLLDHAAER
CGGERVERRRLRCHGAEVVYREPEALRERPESGDLLAVDEAAGLPVDLLAQLLEHAGRIAFATTVHGYEGSGRGFDLRFR
AILDAETPGWQAVRLEAPIRWDRNDPLEAWLGRVLCLDAEPATLEDGGGSAAEIVPVTQDALAQEERRLRQAFGLLVAAH
YRTRPFDLHQLLDGPRRHLFLAEEAGAVVGVVVAAEEGGLDPETAHEVWAERRRPHGHLLPQALATHAGIEMAPTGRALR
IQRIAVHPRRRGHGIGAALVAAVTERARGAGCALVGTSFGATPGLIGFWRACGMHAVAVGARRDAASGEHSALMARGLDE
QGVAWVRQAGFRLGAGAPALLGEPLARMEPQVVLAVLRAAQGAEPPVLSDWQRQELVGFAHSLRGYAAALPALWVLAEVV
LMDPHGSRGRMAHCEAAFIGKVLQHRPWADTAQRLGVPGRRPALAALRQAVADSLPE
>Mature_696_residues
SRRTAVLAGPPQWGRDLAAGQLPDNARICWIGEPPAAGLPEAVTRLAARDGRRVLGRTVDILVYDAHAGLDADALGAAAG
SLRGGGLLVLLTPAWAEWPTRPDPLLGRLIPAGHGRDEAGQRFLRRLMAELEQDPSVTLWTPEQPPPALEPTPPAAPGGA
YAYGCLSADQKTAVEAVMHVVTGHRRRPAVLTADRGRGKSAALGIAVGELLRQRRVQRVVVTAPTIHAAEGLLDHAAERC
GGERVERRRLRCHGAEVVYREPEALRERPESGDLLAVDEAAGLPVDLLAQLLEHAGRIAFATTVHGYEGSGRGFDLRFRA
ILDAETPGWQAVRLEAPIRWDRNDPLEAWLGRVLCLDAEPATLEDGGGSAAEIVPVTQDALAQEERRLRQAFGLLVAAHY
RTRPFDLHQLLDGPRRHLFLAEEAGAVVGVVVAAEEGGLDPETAHEVWAERRRPHGHLLPQALATHAGIEMAPTGRALRI
QRIAVHPRRRGHGIGAALVAAVTERARGAGCALVGTSFGATPGLIGFWRACGMHAVAVGARRDAASGEHSALMARGLDEQ
GVAWVRQAGFRLGAGAPALLGEPLARMEPQVVLAVLRAAQGAEPPVLSDWQRQELVGFAHSLRGYAAALPALWVLAEVVL
MDPHGSRGRMAHCEAAFIGKVLQHRPWADTAQRLGVPGRRPALAALRQAVADSLPE

Specific function: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) [H]

COG id: COG1444

COG function: function code R; Predicted P-loop ATPase fused to an acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI221316741, Length=572, Percent_Identity=24.1258741258741, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI221316723, Length=572, Percent_Identity=24.1258741258741, Blast_Score=84, Evalue=5e-16,
Organism=Escherichia coli, GI1788818, Length=653, Percent_Identity=31.8529862174579, Blast_Score=238, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17507621, Length=584, Percent_Identity=23.6301369863014, Blast_Score=117, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6324197, Length=839, Percent_Identity=19.1895113230036, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24640662, Length=509, Percent_Identity=25.9332023575639, Blast_Score=138, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR013562
- InterPro:   IPR007807 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF08351 DUF1726; PF05127 DUF699 [H]

EC number: NA

Molecular weight: Translated: 74428; Mature: 74297

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRTAVLAGPPQWGRDLAAGQLPDNARICWIGEPPAAGLPEAVTRLAARDGRRVLGRTV
CCCCCEEEECCCHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHHCCEE
DILVYDAHAGLDADALGAAAGSLRGGGLLVLLTPAWAEWPTRPDPLLGRLIPAGHGRDEA
EEEEEECCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCHH
GQRFLRRLMAELEQDPSVTLWTPEQPPPALEPTPPAAPGGAYAYGCLSADQKTAVEAVMH
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
VVTGHRRRPAVLTADRGRGKSAALGIAVGELLRQRRVQRVVVTAPTIHAAEGLLDHAAER
HHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHH
CGGERVERRRLRCHGAEVVYREPEALRERPESGDLLAVDEAAGLPVDLLAQLLEHAGRIA
HCHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCEE
FATTVHGYEGSGRGFDLRFRAILDAETPGWQAVRLEAPIRWDRNDPLEAWLGRVLCLDAE
EEEEEECCCCCCCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHCCEEEECCC
PATLEDGGGSAAEIVPVTQDALAQEERRLRQAFGLLVAAHYRTRPFDLHQLLDGPRRHLF
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHEEE
LAEEAGAVVGVVVAAEEGGLDPETAHEVWAERRRPHGHLLPQALATHAGIEMAPTGRALR
EECCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCCCCCEE
IQRIAVHPRRRGHGIGAALVAAVTERARGAGCALVGTSFGATPGLIGFWRACGMHAVAVG
EEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCHHHEEEC
ARRDAASGEHSALMARGLDEQGVAWVRQAGFRLGAGAPALLGEPLARMEPQVVLAVLRAA
CCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHCCCHHHCCHHHHHHHHHHH
QGAEPPVLSDWQRQELVGFAHSLRGYAAALPALWVLAEVVLMDPHGSRGRMAHCEAAFIG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KVLQHRPWADTAQRLGVPGRRPALAALRQAVADSLPE
HHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRRTAVLAGPPQWGRDLAAGQLPDNARICWIGEPPAAGLPEAVTRLAARDGRRVLGRTV
CCCCEEEECCCHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHHCCEE
DILVYDAHAGLDADALGAAAGSLRGGGLLVLLTPAWAEWPTRPDPLLGRLIPAGHGRDEA
EEEEEECCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCCCCCHH
GQRFLRRLMAELEQDPSVTLWTPEQPPPALEPTPPAAPGGAYAYGCLSADQKTAVEAVMH
HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHH
VVTGHRRRPAVLTADRGRGKSAALGIAVGELLRQRRVQRVVVTAPTIHAAEGLLDHAAER
HHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHH
CGGERVERRRLRCHGAEVVYREPEALRERPESGDLLAVDEAAGLPVDLLAQLLEHAGRIA
HCHHHHHHHHHHHCCCEEEEECCHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCEE
FATTVHGYEGSGRGFDLRFRAILDAETPGWQAVRLEAPIRWDRNDPLEAWLGRVLCLDAE
EEEEEECCCCCCCCEEEEEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHCCEEEECCC
PATLEDGGGSAAEIVPVTQDALAQEERRLRQAFGLLVAAHYRTRPFDLHQLLDGPRRHLF
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHEEE
LAEEAGAVVGVVVAAEEGGLDPETAHEVWAERRRPHGHLLPQALATHAGIEMAPTGRALR
EECCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEECCCCCCEE
IQRIAVHPRRRGHGIGAALVAAVTERARGAGCALVGTSFGATPGLIGFWRACGMHAVAVG
EEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCHHHEEEC
ARRDAASGEHSALMARGLDEQGVAWVRQAGFRLGAGAPALLGEPLARMEPQVVLAVLRAA
CCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHCCCHHHCCHHHHHHHHHHH
QGAEPPVLSDWQRQELVGFAHSLRGYAAALPALWVLAEVVLMDPHGSRGRMAHCEAAFIG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
KVLQHRPWADTAQRLGVPGRRPALAALRQAVADSLPE
HHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA