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The map label for this gene is pfeS [H]

Identifier: 121998099

GI number: 121998099

Start: 1427559

End: 1427930

Strand: Reverse

Name: pfeS [H]

Synonym: Hhal_1317

Alternate gene names: 121998099

Gene position: 1427930-1427559 (Counterclockwise)

Preceding gene: 121998100

Following gene: 121998095

Centisome position: 53.31

GC content: 67.2

Gene sequence:

>372_bases
GTGATTCCGGGGCCCGCACTCACCGTCCAGGCGGACCGGTACTTGCTGCGGGCGGTGATTGAGAACGTCCTACGCAACGC
CTTGCAGCACACCCCGGCGAACAGCAACGTCACGGTAACCTGGCAGCAGGCAGGGGAAGGGGCCGAGATCCGGGTCTGCG
ACGAGGGCGCAGGGGTCCCTGAAGATGAACTCGAGCGGATCTTTGAGCCGTTCCGGCGTCTGCCTTCCGGCACTCGACGC
GGTGGTCACGGGATTGGGCTGGCCATCGCGCGCCATGCGGTCGAGACCCTGGGTGGTGCGATCAAGGCGCGCAACGGCGA
TCCGCACGGCCTGGAAATCGTCCTCTACCTGCCGCGTGGCGGTCGGGGATGA

Upstream 100 bases:

>100_bases
GATCGAGCTCGCCACGCTCATCGAGACGATCGCCCACGATGCGCGCTATGAGTTCGGTGCCGGTTCCGTTGAAGCCGAGG
GGGAGGGGCGATCGGTCACC

Downstream 100 bases:

>100_bases
TGCCGAGGGTGGAGCGGCTGCGCACCCGCGAATGGCAGCGGGGGGGGGGTGTACCGTCTCCGTCGAACAGCCCCGGAGCA
GAGCCCATAGCCGCCGGGGT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MIPGPALTVQADRYLLRAVIENVLRNALQHTPANSNVTVTWQQAGEGAEIRVCDEGAGVPEDELERIFEPFRRLPSGTRR
GGHGIGLAIARHAVETLGGAIKARNGDPHGLEIVLYLPRGGRG

Sequences:

>Translated_123_residues
MIPGPALTVQADRYLLRAVIENVLRNALQHTPANSNVTVTWQQAGEGAEIRVCDEGAGVPEDELERIFEPFRRLPSGTRR
GGHGIGLAIARHAVETLGGAIKARNGDPHGLEIVLYLPRGGRG
>Mature_123_residues
MIPGPALTVQADRYLLRAVIENVLRNALQHTPANSNVTVTWQQAGEGAEIRVCDEGAGVPEDELERIFEPFRRLPSGTRR
GGHGIGLAIARHAVETLGGAIKARNGDPHGLEIVLYLPRGGRG

Specific function: Member of the two-component regulatory system pfeR/pfeS. May activate pfeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=90, Percent_Identity=41.1111111111111, Blast_Score=70, Evalue=5e-14,
Organism=Escherichia coli, GI1790436, Length=110, Percent_Identity=34.5454545454545, Blast_Score=66, Evalue=7e-13,
Organism=Escherichia coli, GI1790346, Length=110, Percent_Identity=35.4545454545455, Blast_Score=65, Evalue=9e-13,
Organism=Escherichia coli, GI1790861, Length=113, Percent_Identity=31.858407079646, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1786783, Length=117, Percent_Identity=34.1880341880342, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1788393, Length=115, Percent_Identity=32.1739130434783, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1788549, Length=116, Percent_Identity=31.0344827586207, Blast_Score=60, Evalue=4e-11,
Organism=Escherichia coli, GI145693157, Length=121, Percent_Identity=29.7520661157025, Blast_Score=59, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 13208; Mature: 13208

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPGPALTVQADRYLLRAVIENVLRNALQHTPANSNVTVTWQQAGEGAEIRVCDEGAGVP
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCC
EDELERIFEPFRRLPSGTRRGGHGIGLAIARHAVETLGGAIKARNGDPHGLEIVLYLPRG
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEECCC
GRG
CCC
>Mature Secondary Structure
MIPGPALTVQADRYLLRAVIENVLRNALQHTPANSNVTVTWQQAGEGAEIRVCDEGAGVP
CCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEECCCCCCC
EDELERIFEPFRRLPSGTRRGGHGIGLAIARHAVETLGGAIKARNGDPHGLEIVLYLPRG
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEECCC
GRG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8361354; 10984043 [H]