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The map label for this gene is norD [H]

Identifier: 121997834

GI number: 121997834

Start: 1127722

End: 1130067

Strand: Reverse

Name: norD [H]

Synonym: Hhal_1043

Alternate gene names: 121997834

Gene position: 1130067-1127722 (Counterclockwise)

Preceding gene: 121997835

Following gene: 121997833

Centisome position: 42.19

GC content: 68.2

Gene sequence:

>2346_bases
ATGACGGTGCGTCTCGAGGACTACCGCGAGACCCTGGTGGCGGCGGATCCGCGGATCGCCGAGACCCTGGAGGCGAGCTT
CGCCGAGGCGTCGCGGGTGATGTCGCCGCGGGGGTTGCACAACTACCTGGAGGGTGCGCGGGCCCTGGCCGAACTCGGCC
GCGGTGCCGACCTGGTCATCGGTTATCTGGAGGCGATGCCGGCGGTGGCCAAGGAGGTCGGTGAGGACGTCCTGCCCGAG
GTGGTCACCGCCGCCATGAAGCTCTCCTCCATGGTCAGCGGCCAGGTGATCGCCCTGCTGCTGGCCGGGCTGCCCACGGC
CGCGCGGCGGCTCGGCGATCCGGACTTGCTGCGCCAGTTCCTCAACCTGGTCCATCAGCTCTCGGCCAAGGCCCCGCGCG
GCCTGCGGCCGATGCTCGAGAACCTCGACGAGCTCTTCACCAAGCTGACCCTCGGCGGATTCCGACGCTGGGCGCTGTGG
GGGGCCCAGGCCCACGCCCGCGACTTCGAGCAGCAGCGGGGTTACTTTGGCCTGCAGACCGCCGACAGCCAGGCGATGCT
CCAGCAGGAGCGCCGCGGCACCCTGCTGGTGGACAACCAGCGCAAACTCAACTTCTATCTGCGGGCCCTGTGGGCGCGTG
ACTTCTTCATGCGCCCGACCTCGGGCGACTTCGAGACCCGCGAGGGGTACAAGCCGTTCATCGAGCAGCGGGTGATCCAC
CTGCCCGATGCCTACGACGATTACCACGGACTGCCCGGCAAGGAGCTCTACCGAGCCGCGGCCGCCCACGCCGCCGCGCA
CCTGTTCTACACCACGGAGCCCTTGTCGCCGGAGATGCTCAATCCGGCGCAGATGGCCGTGATCGGTCTGATCGAGGATG
CCCGGATCGAGGCGCTGGCCATCCACGAGTTTCCGGGGCTGCAGCGACTCTGGCAGCCCTTCCACCAGGCCCGGGCCAGG
GAGCGCGCCGGCGAGGACCCGGACCCGGTGGTCGAGCGCCTGGAACGGGCCGCCCACGCCCTCATCGACCCGGAGTACGC
CGACGAGGATCCCTGGGTGCAGCAGGTCCGCGAACTCTTCGCCTACCACTTCGCGGATCGGCCACGGGATGTGGGGCTCT
CCTGGGAGTTGGGCATGGAGCTGCACAACAGCCTGGCCCAGCGCTATTCCATGCCTTCGGCCCGGGTCCTGGAGCGGGTC
GCCGTTCCCTACCGCGATGACAATCGCTATCTCTTCGCCAGCGACGAGGACGAGTGGCTCGAGGCCGAATATGTCCCGGC
CAGCCACCGTCAGGTGCGCCGCCAGGTCAACCTGATGGAGTTCGTCAACGAGGTCGATTGCGAGCTCGCCGGCGACGACG
CCCAGGAGGTCTGGGTCCTCGGCACGGAGCTCTTCCCCTACGAGGACTACGGGGTGAGCTACAACGAGATGGAAGGGGTG
GAGCCGGTCAGCCCGCCGTTCCACTACCCGGAGTGGGATTACCAGGTCCAGCTCAATCGCCCCGACTGGGTCACGGTGGT
CGAGCGCCGTCCGAAACGCGGCGACCCCGAGGTCATGGATCAGGTCCTCAAGGACTACCGCCCGGTGGCCAGTCGGCTGC
GCTATCTCATCGACGCCCTGCAGCCCCAGGGAGTGATCCGCGAGCGGCGGCAGGAGGACGGCGACGAGCTGGACATCGAC
GCGGCGGTGCGCTCCATGGTGGATCTGCGCCTGGGCATGAGCCCGGATCCGCGCATCAACACCCGGTATATCCGCAAGAC
GCGGGATCTCTCGGTGCTGCTGCTGCTCGACCTCTCCGAGTCCACCAACGACCCGATGGGCGGTAGCGAGAAGACCGTCA
TCGAGTTGACCCGGGAGGCCACGTCGTTGCTCGGCTGGGCCATCAACGGCATCGGTGACCCCTTCGCCGTGCACGGCTTC
TCTTCGGACGGTCGGCACGATGTGCAGTATTACCGGTTCAAGGACTTCCATCAGCCGTGGGGCGAAGAGGCGAAGTCCCG
CCTGGCCGGCATGCGCGGGCAGTACTCGACTCGCATGGGCGCGGCAATGCGCCACGCCGGGGCCCACTTGGTCCGCCAAC
CGCAGCGACGCAAGCTGTTGCTGATTGTCACCGACGGAGAGCCCCACGACGTCGATGTGCGTGATCCGCAGTACCTGCGC
CACGATGCCCGCAAGGCCGCCGAGGAGCTGTCCGCCCGGGGAGTCACCAGCTACTGCCTGACCCTGGACCGGGATGCGGA
CGCCTACGTGTCACGGATCTTCGGGGCCAACGGGTACTCGGTGGTCGAGCAGGTCGAGCGCCTGCCGGAGCGTCTGCCGG
CGGTCTTTGCCCAGCTGACCCGGTAG

Upstream 100 bases:

>100_bases
CTGACCGACGATCCGGACATGCGCGAGACGCTGGATCAGGCGGTGGCGACCTACTTCTGAACAGCCGGGTGATCACCCGG
GGGCAGTGCGGGAGATTGCG

Downstream 100 bases:

>100_bases
CGCCTTATTCGGACCATCAGAACGGTTTGCTTTTGCCGACCGGTCGCGATCCGTAGAGTTTCGGGGCAGTATGGCGGCAA
GCTCGACCTGGGCCGCATCA

Product: von Willebrand factor, type A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 781; Mature: 780

Protein sequence:

>781_residues
MTVRLEDYRETLVAADPRIAETLEASFAEASRVMSPRGLHNYLEGARALAELGRGADLVIGYLEAMPAVAKEVGEDVLPE
VVTAAMKLSSMVSGQVIALLLAGLPTAARRLGDPDLLRQFLNLVHQLSAKAPRGLRPMLENLDELFTKLTLGGFRRWALW
GAQAHARDFEQQRGYFGLQTADSQAMLQQERRGTLLVDNQRKLNFYLRALWARDFFMRPTSGDFETREGYKPFIEQRVIH
LPDAYDDYHGLPGKELYRAAAAHAAAHLFYTTEPLSPEMLNPAQMAVIGLIEDARIEALAIHEFPGLQRLWQPFHQARAR
ERAGEDPDPVVERLERAAHALIDPEYADEDPWVQQVRELFAYHFADRPRDVGLSWELGMELHNSLAQRYSMPSARVLERV
AVPYRDDNRYLFASDEDEWLEAEYVPASHRQVRRQVNLMEFVNEVDCELAGDDAQEVWVLGTELFPYEDYGVSYNEMEGV
EPVSPPFHYPEWDYQVQLNRPDWVTVVERRPKRGDPEVMDQVLKDYRPVASRLRYLIDALQPQGVIRERRQEDGDELDID
AAVRSMVDLRLGMSPDPRINTRYIRKTRDLSVLLLLDLSESTNDPMGGSEKTVIELTREATSLLGWAINGIGDPFAVHGF
SSDGRHDVQYYRFKDFHQPWGEEAKSRLAGMRGQYSTRMGAAMRHAGAHLVRQPQRRKLLLIVTDGEPHDVDVRDPQYLR
HDARKAAEELSARGVTSYCLTLDRDADAYVSRIFGANGYSVVEQVERLPERLPAVFAQLTR

Sequences:

>Translated_781_residues
MTVRLEDYRETLVAADPRIAETLEASFAEASRVMSPRGLHNYLEGARALAELGRGADLVIGYLEAMPAVAKEVGEDVLPE
VVTAAMKLSSMVSGQVIALLLAGLPTAARRLGDPDLLRQFLNLVHQLSAKAPRGLRPMLENLDELFTKLTLGGFRRWALW
GAQAHARDFEQQRGYFGLQTADSQAMLQQERRGTLLVDNQRKLNFYLRALWARDFFMRPTSGDFETREGYKPFIEQRVIH
LPDAYDDYHGLPGKELYRAAAAHAAAHLFYTTEPLSPEMLNPAQMAVIGLIEDARIEALAIHEFPGLQRLWQPFHQARAR
ERAGEDPDPVVERLERAAHALIDPEYADEDPWVQQVRELFAYHFADRPRDVGLSWELGMELHNSLAQRYSMPSARVLERV
AVPYRDDNRYLFASDEDEWLEAEYVPASHRQVRRQVNLMEFVNEVDCELAGDDAQEVWVLGTELFPYEDYGVSYNEMEGV
EPVSPPFHYPEWDYQVQLNRPDWVTVVERRPKRGDPEVMDQVLKDYRPVASRLRYLIDALQPQGVIRERRQEDGDELDID
AAVRSMVDLRLGMSPDPRINTRYIRKTRDLSVLLLLDLSESTNDPMGGSEKTVIELTREATSLLGWAINGIGDPFAVHGF
SSDGRHDVQYYRFKDFHQPWGEEAKSRLAGMRGQYSTRMGAAMRHAGAHLVRQPQRRKLLLIVTDGEPHDVDVRDPQYLR
HDARKAAEELSARGVTSYCLTLDRDADAYVSRIFGANGYSVVEQVERLPERLPAVFAQLTR
>Mature_780_residues
TVRLEDYRETLVAADPRIAETLEASFAEASRVMSPRGLHNYLEGARALAELGRGADLVIGYLEAMPAVAKEVGEDVLPEV
VTAAMKLSSMVSGQVIALLLAGLPTAARRLGDPDLLRQFLNLVHQLSAKAPRGLRPMLENLDELFTKLTLGGFRRWALWG
AQAHARDFEQQRGYFGLQTADSQAMLQQERRGTLLVDNQRKLNFYLRALWARDFFMRPTSGDFETREGYKPFIEQRVIHL
PDAYDDYHGLPGKELYRAAAAHAAAHLFYTTEPLSPEMLNPAQMAVIGLIEDARIEALAIHEFPGLQRLWQPFHQARARE
RAGEDPDPVVERLERAAHALIDPEYADEDPWVQQVRELFAYHFADRPRDVGLSWELGMELHNSLAQRYSMPSARVLERVA
VPYRDDNRYLFASDEDEWLEAEYVPASHRQVRRQVNLMEFVNEVDCELAGDDAQEVWVLGTELFPYEDYGVSYNEMEGVE
PVSPPFHYPEWDYQVQLNRPDWVTVVERRPKRGDPEVMDQVLKDYRPVASRLRYLIDALQPQGVIRERRQEDGDELDIDA
AVRSMVDLRLGMSPDPRINTRYIRKTRDLSVLLLLDLSESTNDPMGGSEKTVIELTREATSLLGWAINGIGDPFAVHGFS
SDGRHDVQYYRFKDFHQPWGEEAKSRLAGMRGQYSTRMGAAMRHAGAHLVRQPQRRKLLLIVTDGEPHDVDVRDPQYLRH
DARKAAEELSARGVTSYCLTLDRDADAYVSRIFGANGYSVVEQVERLPERLPAVFAQLTR

Specific function: Part of the operon norEFCBQD encoding nitric oxide reductase. Essential virulence factor, probably involved in the detoxification of nitric oxide (NO) produced in the macrophages during the innate response against infection [H]

COG id: COG4548

COG function: function code P; Nitric oxide reductase activation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002035 [H]

Pfam domain/function: PF00092 VWA [H]

EC number: NA

Molecular weight: Translated: 88976; Mature: 88844

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50234 VWFA ; PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRLEDYRETLVAADPRIAETLEASFAEASRVMSPRGLHNYLEGARALAELGRGADLVI
CCEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHH
GYLEAMPAVAKEVGEDVLPEVVTAAMKLSSMVSGQVIALLLAGLPTAARRLGDPDLLRQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHH
LNLVHQLSAKAPRGLRPMLENLDELFTKLTLGGFRRWALWGAQAHARDFEQQRGYFGLQT
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
ADSQAMLQQERRGTLLVDNQRKLNFYLRALWARDFFMRPTSGDFETREGYKPFIEQRVIH
CCHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
LPDAYDDYHGLPGKELYRAAAAHAAAHLFYTTEPLSPEMLNPAQMAVIGLIEDARIEALA
CCCCCHHCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEE
IHEFPGLQRLWQPFHQARARERAGEDPDPVVERLERAAHALIDPEYADEDPWVQQVRELF
ECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
AYHFADRPRDVGLSWELGMELHNSLAQRYSMPSARVLERVAVPYRDDNRYLFASDEDEWL
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECCCEEEEECCCCCHH
EAEYVPASHRQVRRQVNLMEFVNEVDCELAGDDAQEVWVLGTELFPYEDYGVSYNEMEGV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHCCCC
EPVSPPFHYPEWDYQVQLNRPDWVTVVERRPKRGDPEVMDQVLKDYRPVASRLRYLIDAL
CCCCCCCCCCCCCEEEEECCCCEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QPQGVIRERRQEDGDELDIDAAVRSMVDLRLGMSPDPRINTRYIRKTRDLSVLLLLDLSE
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEEECCC
STNDPMGGSEKTVIELTREATSLLGWAINGIGDPFAVHGFSSDGRHDVQYYRFKDFHQPW
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHCCCC
GEEAKSRLAGMRGQYSTRMGAAMRHAGAHLVRQPQRRKLLLIVTDGEPHDVDVRDPQYLR
CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHH
HDARKAAEELSARGVTSYCLTLDRDADAYVSRIFGANGYSVVEQVERLPERLPAVFAQLT
HHHHHHHHHHHHCCCCHHHEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
R
C
>Mature Secondary Structure 
TVRLEDYRETLVAADPRIAETLEASFAEASRVMSPRGLHNYLEGARALAELGRGADLVI
CEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHH
GYLEAMPAVAKEVGEDVLPEVVTAAMKLSSMVSGQVIALLLAGLPTAARRLGDPDLLRQF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHH
LNLVHQLSAKAPRGLRPMLENLDELFTKLTLGGFRRWALWGAQAHARDFEQQRGYFGLQT
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
ADSQAMLQQERRGTLLVDNQRKLNFYLRALWARDFFMRPTSGDFETREGYKPFIEQRVIH
CCHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
LPDAYDDYHGLPGKELYRAAAAHAAAHLFYTTEPLSPEMLNPAQMAVIGLIEDARIEALA
CCCCCHHCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHCCEEEEE
IHEFPGLQRLWQPFHQARARERAGEDPDPVVERLERAAHALIDPEYADEDPWVQQVRELF
ECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
AYHFADRPRDVGLSWELGMELHNSLAQRYSMPSARVLERVAVPYRDDNRYLFASDEDEWL
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEECCCEEEEECCCCCHH
EAEYVPASHRQVRRQVNLMEFVNEVDCELAGDDAQEVWVLGTELFPYEDYGVSYNEMEGV
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHCCCC
EPVSPPFHYPEWDYQVQLNRPDWVTVVERRPKRGDPEVMDQVLKDYRPVASRLRYLIDAL
CCCCCCCCCCCCCEEEEECCCCEEEHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QPQGVIRERRQEDGDELDIDAAVRSMVDLRLGMSPDPRINTRYIRKTRDLSVLLLLDLSE
CCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCEEEEEEECCC
STNDPMGGSEKTVIELTREATSLLGWAINGIGDPFAVHGFSSDGRHDVQYYRFKDFHQPW
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHCCCC
GEEAKSRLAGMRGQYSTRMGAAMRHAGAHLVRQPQRRKLLLIVTDGEPHDVDVRDPQYLR
CHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCHHHHH
HDARKAAEELSARGVTSYCLTLDRDADAYVSRIFGANGYSVVEQVERLPERLPAVFAQLT
HHHHHHHHHHHHCCCCHHHEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA