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The map label for this gene is clpX

Identifier: 121997788

GI number: 121997788

Start: 1069311

End: 1070564

Strand: Reverse

Name: clpX

Synonym: Hhal_0997

Alternate gene names: 121997788

Gene position: 1070564-1069311 (Counterclockwise)

Preceding gene: 121997792

Following gene: 121997787

Centisome position: 39.97

GC content: 72.09

Gene sequence:

>1254_bases
ATGCCGGGATGGTGTGGCGATGTATCCGGGGCCTGGTTGGATGTCCCTGAGAGCGCCGCGGGGGTGCCTACAGACGCTGA
GCGGCGCTGCTCGTTCTGCGGGTACGAGGAGCAGATCGCCGGGCCGCTGATCGGCGGTGAGGCGGCCTTCATCTGCGAGC
ACTGCATCGCCAGTTGCAACGCGACCCTGGAAGCTGATCGGCAGCATCGTCAGGAACGTATCCTCGCCGCGCTGCCGGTT
CCGCGCTCGCTGCGACGCTACCTCGACCAGTACGTTGTGGGGCAGGAGCAGGCCAAGAAGGTGCTCTCGGTCGCCGTCTA
CAACCACTATAAGCGGCTGGTGGCGGCGGCCCGCGGCGAGTCGGTGGAGCTGGGTAAGAGCAACATCCTGCTCGTCGGCC
CCAGCGGCACCGGCAAGAGCCACCTGGCCGAGTGCCTGGCGCGCTGTGTCGAGGTCCCCTTCGTGACCGTGGATGCCACC
ACCCTGACCGCTTCGGGCTACGCGGGCGACGACGCCGAGGCGGTGATCGGGCGGCTGCTCGCGGCCTGTGATGGCGACCC
GGAGCGGGCCGCCCGGGGGATCGTCTACATCGACGAGATCGACAAGCTGGCCGCCCGCGACGGGATCGGCGGGGAGCCCG
ACCTGGCCGGCGAGGGGGCGCAGCAGGGCCTGCTCAAGCTCCTCGAGGGTCGCCGGCTCACGGTCTCCAGCGCTGGCCGC
CAGGGCAGTCCGGTCACCGTCGACACGGGTCAGATCCTGTTCATCTGCGGTGGTGCCTTCGAGGGCCTGGAGGCCTTGGC
CGCGCAGCGCCCCGGGGTGGGGTTCACCGCCGCCGCCGACGAGCCGGCGGTGCCGGGCGCCGCCGCCGCCTTGCAGCGCT
TCGGCCTGTTGCCCGAGCTGGTCGGCCGCCTGCCGGTGGTCGAGACCCTGCAGCCGCTAGCCACCGAGCACCTGATCCGC
ATCCTCACCGAGCCGCGCAACGCCTTGGTCCGGCAGTACCAGGTGCTGTTCGCCCGCGATGGCTGCGAGCTGGAGATCAC
CGCCGACGGCCTGGAGGCGGTGGCCCACCGGGCGCGGGCGCGGGGCACCGGGGCCCGTGGCCTGCGCGCGGTGCTGGAAG
AGGTGCTCCTCGAGCCGATGTTCGCCGTCCCCGCCGCTGGCGGCGATGTGGTGCGGCTGACCATCGACGCCGCCGCCGTG
CAGGGCGGTCAGCCGGGCTACGAATGGCGCGCCGCCGTGCGGCACGCCGTCTAA

Upstream 100 bases:

>100_bases
TTTCCGGTCCATGGTGGTGAGTATATCACTCTCAAGGTTGTTGCTGGTTGGCCGTTGCAACGGGGTGAGGCCCATGGCAA
CGAGCAGCGGGGAGAGTGAC

Downstream 100 bases:

>100_bases
AGCTCCTTGATGGTCTGAGTCGAGCGCGATTACTATTGATCGGCTAGCCATTCACCACCCGCCGGCGGGCGGGGCGACTC
GAGACCGACATGCAAGAGAG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MPGWCGDVSGAWLDVPESAAGVPTDAERRCSFCGYEEQIAGPLIGGEAAFICEHCIASCNATLEADRQHRQERILAALPV
PRSLRRYLDQYVVGQEQAKKVLSVAVYNHYKRLVAAARGESVELGKSNILLVGPSGTGKSHLAECLARCVEVPFVTVDAT
TLTASGYAGDDAEAVIGRLLAACDGDPERAARGIVYIDEIDKLAARDGIGGEPDLAGEGAQQGLLKLLEGRRLTVSSAGR
QGSPVTVDTGQILFICGGAFEGLEALAAQRPGVGFTAAADEPAVPGAAAALQRFGLLPELVGRLPVVETLQPLATEHLIR
ILTEPRNALVRQYQVLFARDGCELEITADGLEAVAHRARARGTGARGLRAVLEEVLLEPMFAVPAAGGDVVRLTIDAAAV
QGGQPGYEWRAAVRHAV

Sequences:

>Translated_417_residues
MPGWCGDVSGAWLDVPESAAGVPTDAERRCSFCGYEEQIAGPLIGGEAAFICEHCIASCNATLEADRQHRQERILAALPV
PRSLRRYLDQYVVGQEQAKKVLSVAVYNHYKRLVAAARGESVELGKSNILLVGPSGTGKSHLAECLARCVEVPFVTVDAT
TLTASGYAGDDAEAVIGRLLAACDGDPERAARGIVYIDEIDKLAARDGIGGEPDLAGEGAQQGLLKLLEGRRLTVSSAGR
QGSPVTVDTGQILFICGGAFEGLEALAAQRPGVGFTAAADEPAVPGAAAALQRFGLLPELVGRLPVVETLQPLATEHLIR
ILTEPRNALVRQYQVLFARDGCELEITADGLEAVAHRARARGTGARGLRAVLEEVLLEPMFAVPAAGGDVVRLTIDAAAV
QGGQPGYEWRAAVRHAV
>Mature_416_residues
PGWCGDVSGAWLDVPESAAGVPTDAERRCSFCGYEEQIAGPLIGGEAAFICEHCIASCNATLEADRQHRQERILAALPVP
RSLRRYLDQYVVGQEQAKKVLSVAVYNHYKRLVAAARGESVELGKSNILLVGPSGTGKSHLAECLARCVEVPFVTVDATT
LTASGYAGDDAEAVIGRLLAACDGDPERAARGIVYIDEIDKLAARDGIGGEPDLAGEGAQQGLLKLLEGRRLTVSSAGRQ
GSPVTVDTGQILFICGGAFEGLEALAAQRPGVGFTAAADEPAVPGAAAALQRFGLLPELVGRLPVVETLQPLATEHLIRI
LTEPRNALVRQYQVLFARDGCELEITADGLEAVAHRARARGTGARGLRAVLEEVLLEPMFAVPAAGGDVVRLTIDAAAVQ
GGQPGYEWRAAVRHAV

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=331, Percent_Identity=44.1087613293051, Blast_Score=254, Evalue=1e-67,
Organism=Escherichia coli, GI1786642, Length=392, Percent_Identity=48.7244897959184, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI1790366, Length=213, Percent_Identity=36.6197183098592, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988663, Length=394, Percent_Identity=35.0253807106599, Blast_Score=218, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI71982908, Length=312, Percent_Identity=39.7435897435897, Blast_Score=214, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI71982905, Length=312, Percent_Identity=39.7435897435897, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI71988660, Length=241, Percent_Identity=38.5892116182573, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6319704, Length=431, Percent_Identity=33.8747099767981, Blast_Score=236, Evalue=4e-63,
Organism=Drosophila melanogaster, GI24648289, Length=321, Percent_Identity=42.0560747663551, Blast_Score=234, Evalue=6e-62,
Organism=Drosophila melanogaster, GI24648291, Length=321, Percent_Identity=42.0560747663551, Blast_Score=234, Evalue=6e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 43867; Mature: 43736

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGWCGDVSGAWLDVPESAAGVPTDAERRCSFCGYEEQIAGPLIGGEAAFICEHCIASCN
CCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHCC
ATLEADRQHRQERILAALPVPRSLRRYLDQYVVGQEQAKKVLSVAVYNHYKRLVAAARGE
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SVELGKSNILLVGPSGTGKSHLAECLARCVEVPFVTVDATTLTASGYAGDDAEAVIGRLL
CEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCEEEEECEEEEECCCCCCHHHHHHHHHH
AACDGDPERAARGIVYIDEIDKLAARDGIGGEPDLAGEGAQQGLLKLLEGRRLTVSSAGR
HHCCCCHHHHHCCCEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCC
QGSPVTVDTGQILFICGGAFEGLEALAAQRPGVGFTAAADEPAVPGAAAALQRFGLLPEL
CCCCEEEECCCEEEEECCHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHCCHHHH
VGRLPVVETLQPLATEHLIRILTEPRNALVRQYQVLFARDGCELEITADGLEAVAHRARA
HCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHHHHH
RGTGARGLRAVLEEVLLEPMFAVPAAGGDVVRLTIDAAAVQGGQPGYEWRAAVRHAV
CCCCHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEEEHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
PGWCGDVSGAWLDVPESAAGVPTDAERRCSFCGYEEQIAGPLIGGEAAFICEHCIASCN
CCCCCCCCCCEEECCCCCCCCCCCHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHHHHCC
ATLEADRQHRQERILAALPVPRSLRRYLDQYVVGQEQAKKVLSVAVYNHYKRLVAAARGE
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
SVELGKSNILLVGPSGTGKSHLAECLARCVEVPFVTVDATTLTASGYAGDDAEAVIGRLL
CEEECCCCEEEECCCCCCHHHHHHHHHHHHHCCEEEEECEEEEECCCCCCHHHHHHHHHH
AACDGDPERAARGIVYIDEIDKLAARDGIGGEPDLAGEGAQQGLLKLLEGRRLTVSSAGR
HHCCCCHHHHHCCCEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCC
QGSPVTVDTGQILFICGGAFEGLEALAAQRPGVGFTAAADEPAVPGAAAALQRFGLLPEL
CCCCEEEECCCEEEEECCHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHHCCHHHH
VGRLPVVETLQPLATEHLIRILTEPRNALVRQYQVLFARDGCELEITADGLEAVAHRARA
HCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEECCCCEEEEEHHHHHHHHHHHHH
RGTGARGLRAVLEEVLLEPMFAVPAAGGDVVRLTIDAAAVQGGQPGYEWRAAVRHAV
CCCCHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEEEHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA