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The map label for this gene is aroF [H]

Identifier: 121997787

GI number: 121997787

Start: 1068145

End: 1069221

Strand: Reverse

Name: aroF [H]

Synonym: Hhal_0996

Alternate gene names: 121997787

Gene position: 1069221-1068145 (Counterclockwise)

Preceding gene: 121997788

Following gene: 121997786

Centisome position: 39.92

GC content: 66.76

Gene sequence:

>1077_bases
ATGCAAGAGAGCGATCACGTCAACGACGTCAATGTGGCCACCGGTGAACGCCTTCCGTCTCCGGCCGAGATCAAGTCCGA
GGTCCCGCTGACGGATGCCGCCCGGCAGACCGTGCTGGACGGGCGGCAGGTCCTGCGGGACATCCTCGACGGCAAGGATC
AGCGCATCTTCGCCGTGGTCGGGCCGTGCTCCATCCACGACCCGGAGGCGGCGCTCGACTACGCGCGGCGGCTCAAGGCG
CTGCACGATGAGCTCAGCGATCACATCTACTTGGTGATGCGGGTTTACTTCGAGAAACCGCGCACCACCACGGGCTGGAA
GGGGCTGATCAACGACCCGGACATGGACGACTCCTTCCGGATCGATAAGGGCCTGCGCATGGGCCGCGAGCTGCTCCGCG
AGATCGCCGCCATGGGGCTGCCCACGGCGACTGAGGCCCTCGACCCCTACGCACCGCAATACTACGGCGACCTGGTTTCG
TGGACCGCGATCGGCGCGCGTACCACCGAGTCCCAGACCCACCGCGAGATGGCCAGCGGGCTGTCCACGCCGGTGGGCTT
CAAGAACGCCACTGACGGCAGCCAGACGGTGGCGATCAACGCCCTGCAATCGGCGGCGTCCCCCCACAGTTTCCTGGGCA
TCGACCAGGAGGGCCGCATCACCGTCATCCGTACCCGGGGCAACCAGTACGGCCACGTCGTGCTGCGGGGCGGGGCGCAG
CCCAACTACGACTCGGTGAGTATCCGGCTGTGCGAGCAGGCGCTGGAGAAGGCCGGCATGCCGCTGCGCGTGGTGGTCGA
CTGCAGCCACTCCAACTCCAACAAGGATCCCGGGCTACAGTCGATGGTGCTGGAGGACGTGATCCGTCAGCTCCGCGAGG
GCAATCGCTCCATCGTCGGGGTGATGCTGGAGAGCAACATCGGTTGGGGCAGTCAGAAGCTCGGTGCCGATCCGGGTGCC
CTGGACTACGGCATCTCCATCACCGATGCTTGTATCGACTGGGAGACCACCGAACAGGTTCTCCGGGACGCCGCGGGGCA
GCTGCGCGGCAGCCTGCGCGAGCGCGAGCTGCTGTAG

Upstream 100 bases:

>100_bases
ACGCCGTCTAAAGCTCCTTGATGGTCTGAGTCGAGCGCGATTACTATTGATCGGCTAGCCATTCACCACCCGCCGGCGGG
CGGGGCGACTCGAGACCGAC

Downstream 100 bases:

>100_bases
TTGACTCTGCGCAATGGCTGATGTATTTCTCTCGGGCCAATGTGCTGTGCTGAGCGCAGTCCGGGGGCTTCGCTGAGGGC
GGCGAGGGCCGCAAAGGGAG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MQESDHVNDVNVATGERLPSPAEIKSEVPLTDAARQTVLDGRQVLRDILDGKDQRIFAVVGPCSIHDPEAALDYARRLKA
LHDELSDHIYLVMRVYFEKPRTTTGWKGLINDPDMDDSFRIDKGLRMGRELLREIAAMGLPTATEALDPYAPQYYGDLVS
WTAIGARTTESQTHREMASGLSTPVGFKNATDGSQTVAINALQSAASPHSFLGIDQEGRITVIRTRGNQYGHVVLRGGAQ
PNYDSVSIRLCEQALEKAGMPLRVVVDCSHSNSNKDPGLQSMVLEDVIRQLREGNRSIVGVMLESNIGWGSQKLGADPGA
LDYGISITDACIDWETTEQVLRDAAGQLRGSLRERELL

Sequences:

>Translated_358_residues
MQESDHVNDVNVATGERLPSPAEIKSEVPLTDAARQTVLDGRQVLRDILDGKDQRIFAVVGPCSIHDPEAALDYARRLKA
LHDELSDHIYLVMRVYFEKPRTTTGWKGLINDPDMDDSFRIDKGLRMGRELLREIAAMGLPTATEALDPYAPQYYGDLVS
WTAIGARTTESQTHREMASGLSTPVGFKNATDGSQTVAINALQSAASPHSFLGIDQEGRITVIRTRGNQYGHVVLRGGAQ
PNYDSVSIRLCEQALEKAGMPLRVVVDCSHSNSNKDPGLQSMVLEDVIRQLREGNRSIVGVMLESNIGWGSQKLGADPGA
LDYGISITDACIDWETTEQVLRDAAGQLRGSLRERELL
>Mature_358_residues
MQESDHVNDVNVATGERLPSPAEIKSEVPLTDAARQTVLDGRQVLRDILDGKDQRIFAVVGPCSIHDPEAALDYARRLKA
LHDELSDHIYLVMRVYFEKPRTTTGWKGLINDPDMDDSFRIDKGLRMGRELLREIAAMGLPTATEALDPYAPQYYGDLVS
WTAIGARTTESQTHREMASGLSTPVGFKNATDGSQTVAINALQSAASPHSFLGIDQEGRITVIRTRGNQYGHVVLRGGAQ
PNYDSVSIRLCEQALEKAGMPLRVVVDCSHSNSNKDPGLQSMVLEDVIRQLREGNRSIVGVMLESNIGWGSQKLGADPGA
LDYGISITDACIDWETTEQVLRDAAGQLRGSLRERELL

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=353, Percent_Identity=55.2407932011331, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI1786969, Length=343, Percent_Identity=50.4373177842566, Blast_Score=350, Evalue=6e-98,
Organism=Escherichia coli, GI1787996, Length=342, Percent_Identity=45.906432748538, Blast_Score=328, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6319726, Length=346, Percent_Identity=50.2890173410405, Blast_Score=336, Evalue=4e-93,
Organism=Saccharomyces cerevisiae, GI6320240, Length=339, Percent_Identity=48.377581120944, Blast_Score=324, Evalue=1e-89,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 39281; Mature: 39281

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQESDHVNDVNVATGERLPSPAEIKSEVPLTDAARQTVLDGRQVLRDILDGKDQRIFAVV
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GPCSIHDPEAALDYARRLKALHDELSDHIYLVMRVYFEKPRTTTGWKGLINDPDMDDSFR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
IDKGLRMGRELLREIAAMGLPTATEALDPYAPQYYGDLVSWTAIGARTTESQTHREMASG
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHC
LSTPVGFKNATDGSQTVAINALQSAASPHSFLGIDQEGRITVIRTRGNQYGHVVLRGGAQ
CCCCCCCCCCCCCCCEEEHHHHHHCCCCCCEECCCCCCCEEEEEECCCCCCEEEEECCCC
PNYDSVSIRLCEQALEKAGMPLRVVVDCSHSNSNKDPGLQSMVLEDVIRQLREGNRSIVG
CCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
VMLESNIGWGSQKLGADPGALDYGISITDACIDWETTEQVLRDAAGQLRGSLRERELL
EEEECCCCCCCHHCCCCCCCEECCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQESDHVNDVNVATGERLPSPAEIKSEVPLTDAARQTVLDGRQVLRDILDGKDQRIFAVV
CCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEE
GPCSIHDPEAALDYARRLKALHDELSDHIYLVMRVYFEKPRTTTGWKGLINDPDMDDSFR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
IDKGLRMGRELLREIAAMGLPTATEALDPYAPQYYGDLVSWTAIGARTTESQTHREMASG
HHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHC
LSTPVGFKNATDGSQTVAINALQSAASPHSFLGIDQEGRITVIRTRGNQYGHVVLRGGAQ
CCCCCCCCCCCCCCCEEEHHHHHHCCCCCCEECCCCCCCEEEEEECCCCCCEEEEECCCC
PNYDSVSIRLCEQALEKAGMPLRVVVDCSHSNSNKDPGLQSMVLEDVIRQLREGNRSIVG
CCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
VMLESNIGWGSQKLGADPGALDYGISITDACIDWETTEQVLRDAAGQLRGSLRERELL
EEEECCCCCCCHHCCCCCCCEECCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]