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The map label for this gene is ubiE [C]

Identifier: 121997775

GI number: 121997775

Start: 1057036

End: 1057938

Strand: Reverse

Name: ubiE [C]

Synonym: Hhal_0984

Alternate gene names: 121997775

Gene position: 1057938-1057036 (Counterclockwise)

Preceding gene: 121997777

Following gene: 121997774

Centisome position: 39.5

GC content: 69.88

Gene sequence:

>903_bases
ATGCCCCCAGTACCCACTTCACCGGATCGCCGCGGCACTGGCGGTCGTGCCCTCAGCTATCTCGACTGGTTGTTCAATCC
GTTTCAGCGGCGTGACGCCCAGGCGGTCTACGATCTGCTGGGTACCGGCGCCATCACCGCCGAAGGTCTCTACCTCAACC
TGGGCTACTGGACCGGGGAAGAAGACCTGGACGCGGCCAGCGCGGCGCTGGCGCGGCTGGTCGCCGATACGGCCGGCATG
GGTCCCGAGGATACGGTGCTCGATGTCGGGTTCGGCTTCGCCGATCAGGATCTGCTCTGGGCGCGGATCCACCAGCCGCA
GCGGATCATCGGCCTGAATATCACCGCCTCCCAGGTGGCAGTGGCCCGCGAGCGCCTAGCCGAGGTCGGGCTGGAGGGGC
AGATCGAGCTCCACGAGGGATCGGCCACCGCCATGCCGCTGGAGGACGCCTCGGTCGACTGCGTGGTGGCCCTGGAGTCC
GCCTTCCACTTCCAGACCCGGGCCGAGTTCTTCGCCGAGGCCTACCGGGTCCTGCGCCCCGGTGGTCGCCTGGTCACCGC
GGACATCGTGCCGCTGCCGCGCGCCGCCCGGGTTGCCGAGCGACTGCGCCAGCGCCTGTCGTGGTGGCTGGTCGCCAGTC
GTTTTGCCATCCCCGAGGCCAACCGCTACACCCGGCTCGCCTATCCGGGGTATCTGACCGCGGCCGGGTTTGTGGACGTG
CACGTGCGTTCGATCCGCGAGGACGTCTATGCGCCGCTGCACGCCTGGCTGCAGGCCCACCCGGAGACCCTCGAGCGGCT
CCATCCGATGGCCCGTCTGCCGGCCCGCTGGGCGCGGCGTATGGAGGCTGAGCGGCTCTACGCCGGGCTGGACTACATCC
TAGCCCGGGCCGTCCGCCCTTAG

Upstream 100 bases:

>100_bases
GGGTGTTCGTCGCTAAGCTAATCCCTTACTGAAACTGGGGCGCTAAGGGCTGCTCATCTCCTTAAGATGAGTCCTGTATC
CACCCGTCCGTGAGCCCCGT

Downstream 100 bases:

>100_bases
GGCCGGGCGATGGGCGAGGCACTTCGACGCCGACCCTAGTCCAGGCCGCGCCTGAATCGGCTATCATGCCCCGATGACCA
TGGGAACGCACGACGAGGAC

Product: type 11 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; Arsenite S-Adenosylmethyltransferase; UbiE/COQ5 Family Methlytransferase; Gamma-copherol Methyltransferase; Erythromycin C Methlytransferase; McyJ Protein; Methlytransferase

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MPPVPTSPDRRGTGGRALSYLDWLFNPFQRRDAQAVYDLLGTGAITAEGLYLNLGYWTGEEDLDAASAALARLVADTAGM
GPEDTVLDVGFGFADQDLLWARIHQPQRIIGLNITASQVAVARERLAEVGLEGQIELHEGSATAMPLEDASVDCVVALES
AFHFQTRAEFFAEAYRVLRPGGRLVTADIVPLPRAARVAERLRQRLSWWLVASRFAIPEANRYTRLAYPGYLTAAGFVDV
HVRSIREDVYAPLHAWLQAHPETLERLHPMARLPARWARRMEAERLYAGLDYILARAVRP

Sequences:

>Translated_300_residues
MPPVPTSPDRRGTGGRALSYLDWLFNPFQRRDAQAVYDLLGTGAITAEGLYLNLGYWTGEEDLDAASAALARLVADTAGM
GPEDTVLDVGFGFADQDLLWARIHQPQRIIGLNITASQVAVARERLAEVGLEGQIELHEGSATAMPLEDASVDCVVALES
AFHFQTRAEFFAEAYRVLRPGGRLVTADIVPLPRAARVAERLRQRLSWWLVASRFAIPEANRYTRLAYPGYLTAAGFVDV
HVRSIREDVYAPLHAWLQAHPETLERLHPMARLPARWARRMEAERLYAGLDYILARAVRP
>Mature_299_residues
PPVPTSPDRRGTGGRALSYLDWLFNPFQRRDAQAVYDLLGTGAITAEGLYLNLGYWTGEEDLDAASAALARLVADTAGMG
PEDTVLDVGFGFADQDLLWARIHQPQRIIGLNITASQVAVARERLAEVGLEGQIELHEGSATAMPLEDASVDCVVALESA
FHFQTRAEFFAEAYRVLRPGGRLVTADIVPLPRAARVAERLRQRLSWWLVASRFAIPEANRYTRLAYPGYLTAAGFVDVH
VRSIREDVYAPLHAWLQAHPETLERLHPMARLPARWARRMEAERLYAGLDYILARAVRP

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI48994983, Length=130, Percent_Identity=28.4615384615385, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33371; Mature: 33240

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPVPTSPDRRGTGGRALSYLDWLFNPFQRRDAQAVYDLLGTGAITAEGLYLNLGYWTGE
CCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEECCEEEEEEEECCC
EDLDAASAALARLVADTAGMGPEDTVLDVGFGFADQDLLWARIHQPQRIIGLNITASQVA
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHCCCCEEEEECCHHHHHH
VARERLAEVGLEGQIELHEGSATAMPLEDASVDCVVALESAFHFQTRAEFFAEAYRVLRP
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC
GGRLVTADIVPLPRAARVAERLRQRLSWWLVASRFAIPEANRYTRLAYPGYLTAAGFVDV
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHH
HVRSIREDVYAPLHAWLQAHPETLERLHPMARLPARWARRMEAERLYAGLDYILARAVRP
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PPVPTSPDRRGTGGRALSYLDWLFNPFQRRDAQAVYDLLGTGAITAEGLYLNLGYWTGE
CCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEECCEEEEEEEECCC
EDLDAASAALARLVADTAGMGPEDTVLDVGFGFADQDLLWARIHQPQRIIGLNITASQVA
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHCCCCEEEEECCHHHHHH
VARERLAEVGLEGQIELHEGSATAMPLEDASVDCVVALESAFHFQTRAEFFAEAYRVLRP
HHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCC
GGRLVTADIVPLPRAARVAERLRQRLSWWLVASRFAIPEANRYTRLAYPGYLTAAGFVDV
CCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHH
HVRSIREDVYAPLHAWLQAHPETLERLHPMARLPARWARRMEAERLYAGLDYILARAVRP
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA