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The map label for this gene is ptsP [H]

Identifier: 121997675

GI number: 121997675

Start: 961250

End: 963517

Strand: Reverse

Name: ptsP [H]

Synonym: Hhal_0884

Alternate gene names: 121997675

Gene position: 963517-961250 (Counterclockwise)

Preceding gene: 121997676

Following gene: 121997674

Centisome position: 35.97

GC content: 69.75

Gene sequence:

>2268_bases
ATGCTCGAAATCCTCCACCGCGTCTCCCGAGAAGTGAACGCCGCCCCGAACCTGCGCCAGGGGCTGCGGATCATCGTCGA
GCGGGTCGCCGATGCCATGGCGGTGGATGTCTGCTCGGTGTACCTCCTCGACGCCACCCAGGGCGACTTCGTCCTCATGG
ACACCCGTGGCCTGAACACCGAGTCGGTGGGCCGCGTACGCCTGACCTCCGCCGAGGGGCTGGTGGGCCTGGTGGCCGAG
CGCGAGGAGCCGATCAACCTCAAGAACGCCCCGGCGCACTCGCGGTTTCGCTACTTCCCCGAGACCGGCGAGGAGCGCTA
CTCCTCCTTTCTCGGGGTGCCCATCATCCACTACCGCTCGGTGCTCGGTGTGCTGGTGGTCCAGCAGGCCGAAGAGCGCC
GCTTCGAGGAGAACGAGGTCGCCTTCCTGGTCACCCTGGCGGCGCAGCTGGCCGGGGCGATCGCCCACGCCCGGGCCAGC
GGCGGGATCCACGACATCGGCGACGAGCCGGTGGCCGGGGACAGTCGCGCCCTGCGCGGTCTGCCCGGGGCCCCGGGGGT
GGCCATCGGCACGGCGGTGGTCCCCTATGCCCAGTCGGACCTCAACGCCATCCCCGATCGTACGGCCGCCGACCCCGAGG
CCGAGGTGGCGACCTTCGAGGCCGCCGTCGACCAGGTCACCGCCGAGCTGCGCCAGCTCGGCCAGCAGATCTCCGGCTCG
GTCAGCGCCGACGAGCAGATGCTCTTCGATGTCTATCTGCGCATGCTCGAAGGCGATAGCCTGGTCAGCGAGACCGTCGA
GCGCATCCGCGCCGGCAACTGGGCGCCCGGCGCGTTGCGCCAGGTCATCGGGGAGCACGTGCAGGTCTTCGAGAACATGG
ACGACCCCTACCTGCGCGAGCGGGCCAGCGACATCCGCGACCTTGGGCGGCGGATCCTCGGGCGCCTGCGCGATGAGGGC
GGACGGGTGGAGGACCTGCCCGAGAAGGCCGTGTTGGTCGGCCACGAGGTCAGCGCCTCGCAACTGGCCGAGATCCCCAG
TGATCGGCTGGTCGGTGTTGTCTCGGCGACCGGTTCGCGCAACTCCCACGTGGCCATCCTCGCCCGCGCCCTGGGTATCC
CGGCGGTGATGGGGGTGGACGACCTGCGGACCCGGAAGATGGACGGCCGGCCGGTGGTGGTCGACGGCTACGCGGGGCGC
TTCTACGTCGATCCCACGGAGACCGTGGAGCAGGAGTATCAGCGCCTGATCCGCGACGAGGCGGAGTTCACCGAAGGGCT
CGAGGCGGTGCGCGACGAGCCGGCGATCAGCCCCGACGGCCGCAACCTGGCCCTCTACGCCAACACCGGCCTGATCTCCG
ATATCAATCTGTCGCTGGCGGCCGGTTGTGACGGCATCGGGCTGCACCGCACCGAGTTCCCGTTCCTGATCCGTGACCGC
TTCCCGGGCGAAGAGGAGCAGGCTGACCTCTACCGCCGGGTGCTGGAGCAGTTCGCACCGAAGCCCGTCACCCTGCGTAC
CCTGGATGTCGGCGGCGACAAGTCGCTGGCCTACTTCCCCATCGAGGAAGAGAACCCCTTCCTCGGTTGGCGGGGGATCC
GCCTGACCCTGGACCACCCGGAGATCTTCCTCACCCAGCTGCGCGCCATGCTGCGCGCCGACGTTGGCCTGGGGAATCTG
CAGATCCTCCTGCCCATGGTCAGTCGCCTGGAGGAGATCGCCGACGTGCGTCGGCTGTTGCTGCGCGCCCGCCAGGAGCT
GGCCGAGGAGGGCATCCAGGCGCGCATCCCGCCCCTGGGCGTGATGATCGAGGTGCCTGCCACCATCTACCAGATCGATC
GCTACTGCGATCAGGCCGACTTCCTCTCCCTCGGCTCCAACGACCTGACCCAGTACCTGCTGGCTGTGGATCGCAACAAC
AGCCGCGTGGCCGGGCTCTACGACGAGCTGCACCCGGCCGTGCTCGGCGCGGTGCAGCACGTGGCCCAGGCGGCGCGGCG
CCACGGCAAACGTCTGACCGTCTGCGGCGGCATGGCCGGCGATCCGGCCGGGGCCATCCTGCTCATGGGCTTCGGCATCG
AAGGGTTATCGATGAGCGTCTCGAGCCTGCTGCGCATCAAGTGGGTGGTGCGCCGCGTGCCCGTCCGGCGCGCCGCCGAG
CTGGCCAACCGGGCCGTCGAGATGGACTCCCCCGAGGAGGTGCGCCGCATGCTCCGCCGTACCCTGGAGGAGTACGAGCT
CGGCGGCCTCATGCGGGCGGGCAAGTAA

Upstream 100 bases:

>100_bases
ATCTGCAGGCCGATGACTGGGCCGGCACCGGCACCGAGGGTGGCCCCGCTGCGGTCATCCCGCCGGCGGCTCGGCGCCGA
TTGCGATAGGGCGGGGCTTG

Downstream 100 bases:

>100_bases
TCGCTCGCAATTGACAATCACTCGCGTTCAAGGTTTGATGGTGATCAGTCGTGATGATCGGGGCCTGCCATGTACGTCTG
CATCTGTAACGCCGTAACCG

Product: phosphoenolpyruvate-protein phosphotransferase PtsP

Products: NA

Alternate protein names: Enzyme I-Ntr; Phosphotransferase system, enzyme I [H]

Number of amino acids: Translated: 755; Mature: 755

Protein sequence:

>755_residues
MLEILHRVSREVNAAPNLRQGLRIIVERVADAMAVDVCSVYLLDATQGDFVLMDTRGLNTESVGRVRLTSAEGLVGLVAE
REEPINLKNAPAHSRFRYFPETGEERYSSFLGVPIIHYRSVLGVLVVQQAEERRFEENEVAFLVTLAAQLAGAIAHARAS
GGIHDIGDEPVAGDSRALRGLPGAPGVAIGTAVVPYAQSDLNAIPDRTAADPEAEVATFEAAVDQVTAELRQLGQQISGS
VSADEQMLFDVYLRMLEGDSLVSETVERIRAGNWAPGALRQVIGEHVQVFENMDDPYLRERASDIRDLGRRILGRLRDEG
GRVEDLPEKAVLVGHEVSASQLAEIPSDRLVGVVSATGSRNSHVAILARALGIPAVMGVDDLRTRKMDGRPVVVDGYAGR
FYVDPTETVEQEYQRLIRDEAEFTEGLEAVRDEPAISPDGRNLALYANTGLISDINLSLAAGCDGIGLHRTEFPFLIRDR
FPGEEEQADLYRRVLEQFAPKPVTLRTLDVGGDKSLAYFPIEEENPFLGWRGIRLTLDHPEIFLTQLRAMLRADVGLGNL
QILLPMVSRLEEIADVRRLLLRARQELAEEGIQARIPPLGVMIEVPATIYQIDRYCDQADFLSLGSNDLTQYLLAVDRNN
SRVAGLYDELHPAVLGAVQHVAQAARRHGKRLTVCGGMAGDPAGAILLMGFGIEGLSMSVSSLLRIKWVVRRVPVRRAAE
LANRAVEMDSPEEVRRMLRRTLEEYELGGLMRAGK

Sequences:

>Translated_755_residues
MLEILHRVSREVNAAPNLRQGLRIIVERVADAMAVDVCSVYLLDATQGDFVLMDTRGLNTESVGRVRLTSAEGLVGLVAE
REEPINLKNAPAHSRFRYFPETGEERYSSFLGVPIIHYRSVLGVLVVQQAEERRFEENEVAFLVTLAAQLAGAIAHARAS
GGIHDIGDEPVAGDSRALRGLPGAPGVAIGTAVVPYAQSDLNAIPDRTAADPEAEVATFEAAVDQVTAELRQLGQQISGS
VSADEQMLFDVYLRMLEGDSLVSETVERIRAGNWAPGALRQVIGEHVQVFENMDDPYLRERASDIRDLGRRILGRLRDEG
GRVEDLPEKAVLVGHEVSASQLAEIPSDRLVGVVSATGSRNSHVAILARALGIPAVMGVDDLRTRKMDGRPVVVDGYAGR
FYVDPTETVEQEYQRLIRDEAEFTEGLEAVRDEPAISPDGRNLALYANTGLISDINLSLAAGCDGIGLHRTEFPFLIRDR
FPGEEEQADLYRRVLEQFAPKPVTLRTLDVGGDKSLAYFPIEEENPFLGWRGIRLTLDHPEIFLTQLRAMLRADVGLGNL
QILLPMVSRLEEIADVRRLLLRARQELAEEGIQARIPPLGVMIEVPATIYQIDRYCDQADFLSLGSNDLTQYLLAVDRNN
SRVAGLYDELHPAVLGAVQHVAQAARRHGKRLTVCGGMAGDPAGAILLMGFGIEGLSMSVSSLLRIKWVVRRVPVRRAAE
LANRAVEMDSPEEVRRMLRRTLEEYELGGLMRAGK
>Mature_755_residues
MLEILHRVSREVNAAPNLRQGLRIIVERVADAMAVDVCSVYLLDATQGDFVLMDTRGLNTESVGRVRLTSAEGLVGLVAE
REEPINLKNAPAHSRFRYFPETGEERYSSFLGVPIIHYRSVLGVLVVQQAEERRFEENEVAFLVTLAAQLAGAIAHARAS
GGIHDIGDEPVAGDSRALRGLPGAPGVAIGTAVVPYAQSDLNAIPDRTAADPEAEVATFEAAVDQVTAELRQLGQQISGS
VSADEQMLFDVYLRMLEGDSLVSETVERIRAGNWAPGALRQVIGEHVQVFENMDDPYLRERASDIRDLGRRILGRLRDEG
GRVEDLPEKAVLVGHEVSASQLAEIPSDRLVGVVSATGSRNSHVAILARALGIPAVMGVDDLRTRKMDGRPVVVDGYAGR
FYVDPTETVEQEYQRLIRDEAEFTEGLEAVRDEPAISPDGRNLALYANTGLISDINLSLAAGCDGIGLHRTEFPFLIRDR
FPGEEEQADLYRRVLEQFAPKPVTLRTLDVGGDKSLAYFPIEEENPFLGWRGIRLTLDHPEIFLTQLRAMLRADVGLGNL
QILLPMVSRLEEIADVRRLLLRARQELAEEGIQARIPPLGVMIEVPATIYQIDRYCDQADFLSLGSNDLTQYLLAVDRNN
SRVAGLYDELHPAVLGAVQHVAQAARRHGKRLTVCGGMAGDPAGAILLMGFGIEGLSMSVSSLLRIKWVVRRVPVRRAAE
LANRAVEMDSPEEVRRMLRRTLEEYELGGLMRAGK

Specific function: Component of the phosphoenolpyruvate-dependent nitrogen- metabolic phosphotransferase system (nitrogen-metabolic PTS), that seems to be involved in regulating nitrogen metabolism. Enzyme I- Ntr transfers the phosphoryl group from phosphoenolpyruvate (PEP)

COG id: COG3605

COG function: function code T; Signal transduction protein containing GAF and PtsI domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GAF domain [H]

Homologues:

Organism=Escherichia coli, GI1789193, Length=757, Percent_Identity=43.4610303830911, Blast_Score=591, Evalue=1e-170,
Organism=Escherichia coli, GI1788756, Length=576, Percent_Identity=33.8541666666667, Blast_Score=327, Evalue=3e-90,
Organism=Escherichia coli, GI48994992, Length=561, Percent_Identity=33.8680926916221, Blast_Score=275, Evalue=9e-75,
Organism=Escherichia coli, GI1788726, Length=566, Percent_Identity=33.0388692579505, Blast_Score=274, Evalue=1e-74,
Organism=Escherichia coli, GI1787994, Length=406, Percent_Identity=29.064039408867, Blast_Score=115, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003018
- InterPro:   IPR008279
- InterPro:   IPR006318
- InterPro:   IPR018274
- InterPro:   IPR023151
- InterPro:   IPR000121
- InterPro:   IPR008731
- InterPro:   IPR015813 [H]

Pfam domain/function: PF01590 GAF; PF05524 PEP-utilisers_N; PF00391 PEP-utilizers; PF02896 PEP-utilizers_C [H]

EC number: =2.7.3.9 [H]

Molecular weight: Translated: 82964; Mature: 82964

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00742 PEP_ENZYMES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEILHRVSREVNAAPNLRQGLRIIVERVADAMAVDVCSVYLLDATQGDFVLMDTRGLNT
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCC
ESVGRVRLTSAEGLVGLVAEREEPINLKNAPAHSRFRYFPETGEERYSSFLGVPIIHYRS
CCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHH
VLGVLVVQQAEERRFEENEVAFLVTLAAQLAGAIAHARASGGIHDIGDEPVAGDSRALRG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCC
LPGAPGVAIGTAVVPYAQSDLNAIPDRTAADPEAEVATFEAAVDQVTAELRQLGQQISGS
CCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
VSADEQMLFDVYLRMLEGDSLVSETVERIRAGNWAPGALRQVIGEHVQVFENMDDPYLRE
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
RASDIRDLGRRILGRLRDEGGRVEDLPEKAVLVGHEVSASQLAEIPSDRLVGVVSATGSR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCEEEEEEECCCC
NSHVAILARALGIPAVMGVDDLRTRKMDGRPVVVDGYAGRFYVDPTETVEQEYQRLIRDE
CCHHHHHHHHHCCCHHCCCHHHHHCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHH
AEFTEGLEAVRDEPAISPDGRNLALYANTGLISDINLSLAAGCDGIGLHRTEFPFLIRDR
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEECCEEEECCCCCCCCCCCCCCEEEECC
FPGEEEQADLYRRVLEQFAPKPVTLRTLDVGGDKSLAYFPIEEENPFLGWRGIRLTLDHP
CCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEEEEEEECCH
EIFLTQLRAMLRADVGLGNLQILLPMVSRLEEIADVRRLLLRARQELAEEGIQARIPPLG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
VMIEVPATIYQIDRYCDQADFLSLGSNDLTQYLLAVDRNNSRVAGLYDELHPAVLGAVQH
EEEECCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
VAQAARRHGKRLTVCGGMAGDPAGAILLMGFGIEGLSMSVSSLLRIKWVVRRVPVRRAAE
HHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
LANRAVEMDSPEEVRRMLRRTLEEYELGGLMRAGK
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure
MLEILHRVSREVNAAPNLRQGLRIIVERVADAMAVDVCSVYLLDATQGDFVLMDTRGLNT
CHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCC
ESVGRVRLTSAEGLVGLVAEREEPINLKNAPAHSRFRYFPETGEERYSSFLGVPIIHYRS
CCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHH
VLGVLVVQQAEERRFEENEVAFLVTLAAQLAGAIAHARASGGIHDIGDEPVAGDSRALRG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCC
LPGAPGVAIGTAVVPYAQSDLNAIPDRTAADPEAEVATFEAAVDQVTAELRQLGQQISGS
CCCCCCCCHHHHHCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
VSADEQMLFDVYLRMLEGDSLVSETVERIRAGNWAPGALRQVIGEHVQVFENMDDPYLRE
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCHHHHH
RASDIRDLGRRILGRLRDEGGRVEDLPEKAVLVGHEVSASQLAEIPSDRLVGVVSATGSR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHHHHHCCCCCEEEEEEECCCC
NSHVAILARALGIPAVMGVDDLRTRKMDGRPVVVDGYAGRFYVDPTETVEQEYQRLIRDE
CCHHHHHHHHHCCCHHCCCHHHHHCCCCCCCEEEECCCCEEEECCHHHHHHHHHHHHHHH
AEFTEGLEAVRDEPAISPDGRNLALYANTGLISDINLSLAAGCDGIGLHRTEFPFLIRDR
HHHHHHHHHHHCCCCCCCCCCEEEEEECCCCEEECCEEEECCCCCCCCCCCCCCEEEECC
FPGEEEQADLYRRVLEQFAPKPVTLRTLDVGGDKSLAYFPIEEENPFLGWRGIRLTLDHP
CCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCCEEEEEEEEEECCH
EIFLTQLRAMLRADVGLGNLQILLPMVSRLEEIADVRRLLLRARQELAEEGIQARIPPLG
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCC
VMIEVPATIYQIDRYCDQADFLSLGSNDLTQYLLAVDRNNSRVAGLYDELHPAVLGAVQH
EEEECCHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHH
VAQAARRHGKRLTVCGGMAGDPAGAILLMGFGIEGLSMSVSSLLRIKWVVRRVPVRRAAE
HHHHHHHCCCEEEEECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
LANRAVEMDSPEEVRRMLRRTLEEYELGGLMRAGK
HHHHHCCCCCHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 7896715; 8973315 [H]