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The map label for this gene is insF1 [H]

Identifier: 121997558

GI number: 121997558

Start: 848866

End: 849681

Strand: Reverse

Name: insF1 [H]

Synonym: Hhal_0765

Alternate gene names: 121997558

Gene position: 849681-848866 (Counterclockwise)

Preceding gene: 121997559

Following gene: 121997557

Centisome position: 31.72

GC content: 62.75

Gene sequence:

>816_bases
ATGTGCCGCGTCCTTGGCGTCGCTCGCAGCGGCTTCTACGCATGGTGCCGGAACAAGGCGGCCCGCGCCGCACGGGAAGA
ACGCCAGCAGGCCTTTGATGGACAGGTGCAAGAGGCCTTCGAAGACTCCAGGCAACGCTCTGGGGCGCCTCGACTGACGC
GAGAGCTGGACGGGCAAGGCGTGTCGGTCAATCGCAAAACCGTGGCCCGGAGCATGCGCCGTCAGGGCCTCCGGGCACGC
ACGTCACGCCGGTTTAAGGTGACGACGAACTCGGCTCACAGCCTGCCGGTCGCCCCCAATCACTTGGCCCAGTGCTTTGA
AGCGGGGCAGCGGAACCAGAAGTGGACTGGCGACATCACGTATTTTGCGACCGGCGAAGGGTGGCTCTATCTCGCGGTCG
TCCTGGATCTTTGTGGCCGCAAAGTGATCGGTTGGGCCATGCGCGATCAGATGAGCGCTGAACTGGCCTGTGAGGCGCTT
CTGATGGCCCTGGAACGGCGAGGCTACCCCACGGGGGTCATCGTCCATACGGATCGCGGCAGCCAGTACTGCTCCCGTGC
GTACCGCAGGCTCATCAGCGACTACGGGCTGATCAGCAGCATGAGCGCGAAGGGCAGCTGCTACGACAATGCCTGCAACG
AGAGCTTTTTCCGTTCCCTGAAAGTCGAGGCCCTGCATGGCGAGAAATTCCCCACGCGGGCATCGATGCGTGAGGCCGTC
TTCGAATACATTGAGGGCTACTACAATCGCCGGCGTCTTCATAGCACGCTCGGGTACCTATCCCCGGACGACTACGAGGC
CCGGCTTAATAGCTAA

Upstream 100 bases:

>100_bases
AGCTGTCGATCACAAAAAAGGCCGCGGCGTACTTCGCGAAAAACCAAAAGTGAAGTACGCGTTCATCGATCAGCAGCGTC
ACGAGCACCGAGTCCAGGCG

Downstream 100 bases:

>100_bases
CACCGTGTCCACGTTCGCTGGGTAAGACCAGGACAGTGGCAGCGCCTCGGAGAGGGCACCCCGCAGGGCGGGGTGGTCTC
GCCGCTGCTGGCCAATGTCT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MCRVLGVARSGFYAWCRNKAARAAREERQQAFDGQVQEAFEDSRQRSGAPRLTRELDGQGVSVNRKTVARSMRRQGLRAR
TSRRFKVTTNSAHSLPVAPNHLAQCFEAGQRNQKWTGDITYFATGEGWLYLAVVLDLCGRKVIGWAMRDQMSAELACEAL
LMALERRGYPTGVIVHTDRGSQYCSRAYRRLISDYGLISSMSAKGSCYDNACNESFFRSLKVEALHGEKFPTRASMREAV
FEYIEGYYNRRRLHSTLGYLSPDDYEARLNS

Sequences:

>Translated_271_residues
MCRVLGVARSGFYAWCRNKAARAAREERQQAFDGQVQEAFEDSRQRSGAPRLTRELDGQGVSVNRKTVARSMRRQGLRAR
TSRRFKVTTNSAHSLPVAPNHLAQCFEAGQRNQKWTGDITYFATGEGWLYLAVVLDLCGRKVIGWAMRDQMSAELACEAL
LMALERRGYPTGVIVHTDRGSQYCSRAYRRLISDYGLISSMSAKGSCYDNACNESFFRSLKVEALHGEKFPTRASMREAV
FEYIEGYYNRRRLHSTLGYLSPDDYEARLNS
>Mature_271_residues
MCRVLGVARSGFYAWCRNKAARAAREERQQAFDGQVQEAFEDSRQRSGAPRLTRELDGQGVSVNRKTVARSMRRQGLRAR
TSRRFKVTTNSAHSLPVAPNHLAQCFEAGQRNQKWTGDITYFATGEGWLYLAVVLDLCGRKVIGWAMRDQMSAELACEAL
LMALERRGYPTGVIVHTDRGSQYCSRAYRRLISDYGLISSMSAKGSCYDNACNESFFRSLKVEALHGEKFPTRASMREAV
FEYIEGYYNRRRLHSTLGYLSPDDYEARLNS

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=228, Percent_Identity=32.4561403508772, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI1788405, Length=268, Percent_Identity=58.2089552238806, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1787263, Length=268, Percent_Identity=58.2089552238806, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1786753, Length=268, Percent_Identity=58.2089552238806, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1786570, Length=268, Percent_Identity=58.2089552238806, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1786490, Length=268, Percent_Identity=58.2089552238806, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1789981, Length=266, Percent_Identity=31.203007518797, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790724, Length=218, Percent_Identity=29.8165137614679, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1789424, Length=218, Percent_Identity=29.8165137614679, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1789224, Length=218, Percent_Identity=29.8165137614679, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788305, Length=218, Percent_Identity=29.8165137614679, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1787669, Length=218, Percent_Identity=29.8165137614679, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1786558, Length=218, Percent_Identity=29.8165137614679, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 30773; Mature: 30773

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRVLGVARSGFYAWCRNKAARAAREERQQAFDGQVQEAFEDSRQRSGAPRLTRELDGQG
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHCCCC
VSVNRKTVARSMRRQGLRARTSRRFKVTTNSAHSLPVAPNHLAQCFEAGQRNQKWTGDIT
CCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEE
YFATGEGWLYLAVVLDLCGRKVIGWAMRDQMSAELACEALLMALERRGYPTGVIVHTDRG
EEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
SQYCSRAYRRLISDYGLISSMSAKGSCYDNACNESFFRSLKVEALHGEKFPTRASMREAV
HHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
FEYIEGYYNRRRLHSTLGYLSPDDYEARLNS
HHHHHHHHHHHHHHHHHCCCCCCCCHHCCCC
>Mature Secondary Structure
MCRVLGVARSGFYAWCRNKAARAAREERQQAFDGQVQEAFEDSRQRSGAPRLTRELDGQG
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHCCCC
VSVNRKTVARSMRRQGLRARTSRRFKVTTNSAHSLPVAPNHLAQCFEAGQRNQKWTGDIT
CCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCEE
YFATGEGWLYLAVVLDLCGRKVIGWAMRDQMSAELACEALLMALERRGYPTGVIVHTDRG
EEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
SQYCSRAYRRLISDYGLISSMSAKGSCYDNACNESFFRSLKVEALHGEKFPTRASMREAV
HHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
FEYIEGYYNRRRLHSTLGYLSPDDYEARLNS
HHHHHHHHHHHHHHHHHCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]