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The map label for this gene is ilvH

Identifier: 121997491

GI number: 121997491

Start: 775898

End: 776392

Strand: Reverse

Name: ilvH

Synonym: Hhal_0694

Alternate gene names: 121997491

Gene position: 776392-775898 (Counterclockwise)

Preceding gene: 121997493

Following gene: 121997490

Centisome position: 28.99

GC content: 61.62

Gene sequence:

>495_bases
ATGCGGCACATCATCTCGATGCTGGTGGAGAACGAATCCGGAGCGCTGTCGCGCATCTCCGGGATGTTCACGGCCCGTGG
CTACAACATCGAGTGCCTGACGGTGGCTCCCACCGACGACCCGAGCATCTCGCGGCTGACCCTGGTCACCATCGGCGACG
ATCAGATCATCGAGCAGATCATCAAGCAGCTGAACAAGCTGCTCGATGTGATCAAGGTCGTCGACATGACCGAGGGCAAG
CACATCGAGCGCGAGATGATGCTGATCAAGGTCACCGCCGGCGTTGCCGAGCAGCGCGAGGAGTTCAAGCGCCTGACGGA
CATCTTCCGTGGCCGCATCCTCGACGTCACCGAGAAGATCTATACCATCGAGATGACCGGCACGAGTGACAAGCTCGACG
CCTTCATCGAGGCCATCGGCCCGAGCAACATCCTGGAGGTGGTCCGCTCCGGTGTCATCGGCATCAGCCGCGGCGAGCGC
CATCTGCGCGTCTAG

Upstream 100 bases:

>100_bases
AGGGTCAATCGGTTGCGGGCTCGCCTTGCTTGACCTCCAGCCCACCTGCCAGTATTTTCCCGCATTTACTCCGCACGCTG
CGGTCCCGGGGGAGAGCTAC

Downstream 100 bases:

>100_bases
CGCCGTCCCGTCTCATCCCCGCCCGTCCGGTGGCGGGCGGACTCGCGAATCCGTTCAGGGGGAAACATGAAGGTCTATTA
CGATCAGGACGCCGATCTTT

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MRHIISMLVENESGALSRISGMFTARGYNIECLTVAPTDDPSISRLTLVTIGDDQIIEQIIKQLNKLLDVIKVVDMTEGK
HIEREMMLIKVTAGVAEQREEFKRLTDIFRGRILDVTEKIYTIEMTGTSDKLDAFIEAIGPSNILEVVRSGVIGISRGER
HLRV

Sequences:

>Translated_164_residues
MRHIISMLVENESGALSRISGMFTARGYNIECLTVAPTDDPSISRLTLVTIGDDQIIEQIIKQLNKLLDVIKVVDMTEGK
HIEREMMLIKVTAGVAEQREEFKRLTDIFRGRILDVTEKIYTIEMTGTSDKLDAFIEAIGPSNILEVVRSGVIGISRGER
HLRV
>Mature_164_residues
MRHIISMLVENESGALSRISGMFTARGYNIECLTVAPTDDPSISRLTLVTIGDDQIIEQIIKQLNKLLDVIKVVDMTEGK
HIEREMMLIKVTAGVAEQREEFKRLTDIFRGRILDVTEKIYTIEMTGTSDKLDAFIEAIGPSNILEVVRSGVIGISRGER
HLRV

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=164, Percent_Identity=56.7073170731707, Blast_Score=197, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6319837, Length=204, Percent_Identity=27.9411764705882, Blast_Score=100, Evalue=9e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18399; Mature: 18399

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHIISMLVENESGALSRISGMFTARGYNIECLTVAPTDDPSISRLTLVTIGDDQIIEQI
CHHHHHHHHCCCCCHHHHHHHHHEECCCCEEEEEECCCCCCCCCEEEEEEECCHHHHHHH
IKQLNKLLDVIKVVDMTEGKHIEREMMLIKVTAGVAEQREEFKRLTDIFRGRILDVTEKI
HHHHHHHHHHHHHHHCCCCCCHHHHEEEEEEHHCHHHHHHHHHHHHHHHCCCCEECCCEE
YTIEMTGTSDKLDAFIEAIGPSNILEVVRSGVIGISRGERHLRV
EEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCEECCCCCCCCCC
>Mature Secondary Structure
MRHIISMLVENESGALSRISGMFTARGYNIECLTVAPTDDPSISRLTLVTIGDDQIIEQI
CHHHHHHHHCCCCCHHHHHHHHHEECCCCEEEEEECCCCCCCCCEEEEEEECCHHHHHHH
IKQLNKLLDVIKVVDMTEGKHIEREMMLIKVTAGVAEQREEFKRLTDIFRGRILDVTEKI
HHHHHHHHHHHHHHHCCCCCCHHHHEEEEEEHHCHHHHHHHHHHHHHHHCCCCEECCCEE
YTIEMTGTSDKLDAFIEAIGPSNILEVVRSGVIGISRGERHLRV
EEEEECCCCHHHHHHHHHCCCHHHHHHHHCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]