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The map label for this gene is ytfH [C]

Identifier: 121638980

GI number: 121638980

Start: 3418459

End: 3418935

Strand: Direct

Name: ytfH [C]

Synonym: BCG_3120

Alternate gene names: 121638980

Gene position: 3418459-3418935 (Clockwise)

Preceding gene: 121638976

Following gene: 121638981

Centisome position: 78.14

GC content: 65.2

Gene sequence:

>477_bases
ATGGCCGTTTCCGATCTATCCCACCGCTTCGAAGGGGAGTCGGTCGGCCGGGCGCTCGAGCTAGTCGGTGAACGCTGGAC
GCTGCTTATCCTGCGTGAGGCGTTCTTCGGGGTGCGGCGGTTCGGTCAGCTCGCGCGGAACCTTGGCATTCCGCGGCCCA
CGCTGTCCTCGCGGCTGCGGATGCTCGTCGAGGTGGGTCTTTTTGACCGGGTGCCATATTCCTCCGACCCCGAGCGACAC
GAGTACCGGCTCACCGAAGCGGGCCGCGATCTGTTCGCCGCGATCGTCGTCCTCATGCAGTGGGGGGATGAGTACTTGCC
ACGCCCAGAAGGACCACCGATCAAGCTGCGCCACCACACCTGCGGCGAGCACGCCGACCCACGCCTGATCTGTACCCACT
GCGGCGAGGAGATCACCGCGCGCAATGTGACACCTGAACCGGGGCCGGGCTTTAAAGCCAAGCTGGCGTCCTCATAA

Upstream 100 bases:

>100_bases
CGGTTTCGCTTTGGTTCACGGGCGGCTCCTGATGACGGTGGCGGTTCAATGAAGTTACCACCCTTGGTTCAGTCATTGAA
CCAGGTACAGTTGGTGGACC

Downstream 100 bases:

>100_bases
CGATTCCCAACCTCAAATTGTTGCGAATCGATAATGCAAGCCGAACCACGTCGCCGAACAAGGCCGTACACCTTGGCCGG
GAAACTATCGTCATTTTGTG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 157

Protein sequence:

>158_residues
MAVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFGQLARNLGIPRPTLSSRLRMLVEVGLFDRVPYSSDPERH
EYRLTEAGRDLFAAIVVLMQWGDEYLPRPEGPPIKLRHHTCGEHADPRLICTHCGEEITARNVTPEPGPGFKAKLASS

Sequences:

>Translated_158_residues
MAVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFGQLARNLGIPRPTLSSRLRMLVEVGLFDRVPYSSDPERH
EYRLTEAGRDLFAAIVVLMQWGDEYLPRPEGPPIKLRHHTCGEHADPRLICTHCGEEITARNVTPEPGPGFKAKLASS
>Mature_157_residues
AVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFGQLARNLGIPRPTLSSRLRMLVEVGLFDRVPYSSDPERHE
YRLTEAGRDLFAAIVVLMQWGDEYLPRPEGPPIKLRHHTCGEHADPRLICTHCGEEITARNVTPEPGPGFKAKLASS

Specific function: Unknown

COG id: COG1733

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH hxlR-type DNA-binding domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y3095_MYCTU (P0A648)

Other databases:

- EMBL:   BX842581
- EMBL:   AE000516
- PIR:   F70918
- RefSeq:   NP_217611.1
- RefSeq:   NP_337703.1
- ProteinModelPortal:   P0A648
- SMR:   P0A648
- EnsemblBacteria:   EBMYCT00000000807
- EnsemblBacteria:   EBMYCT00000072705
- GeneID:   888679
- GeneID:   926701
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT3179
- KEGG:   mtu:Rv3095
- TIGR:   MT3179
- TubercuList:   Rv3095
- GeneTree:   EBGT00050000015896
- HOGENOM:   HBG752497
- OMA:   MHAVAVC
- ProtClustDB:   CLSK792280
- GO:   GO:0006350
- InterPro:   IPR002577
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10

Pfam domain/function: PF01638 DUF24

EC number: NA

Molecular weight: Translated: 17802; Mature: 17670

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS51118 HTH_HXLR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFGQLARNLGIPRPTLSSRLR
CCCCHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
MLVEVGLFDRVPYSSDPERHEYRLTEAGRDLFAAIVVLMQWGDEYLPRPEGPPIKLRHHT
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCEEEECCC
CGEHADPRLICTHCGEEITARNVTPEPGPGFKAKLASS
CCCCCCCCEEHHHCCCHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AVSDLSHRFEGESVGRALELVGERWTLLILREAFFGVRRFGQLARNLGIPRPTLSSRLR
CCCHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
MLVEVGLFDRVPYSSDPERHEYRLTEAGRDLFAAIVVLMQWGDEYLPRPEGPPIKLRHHT
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCEEEECCC
CGEHADPRLICTHCGEEITARNVTPEPGPGFKAKLASS
CCCCCCCCEEHHHCCCHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036