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The map label for this gene is lipR [H]

Identifier: 121638969

GI number: 121638969

Start: 3404483

End: 3405409

Strand: Direct

Name: lipR [H]

Synonym: BCG_3109

Alternate gene names: 121638969

Gene position: 3404483-3405409 (Clockwise)

Preceding gene: 121638968

Following gene: 121638970

Centisome position: 77.83

GC content: 69.36

Gene sequence:

>927_bases
ATGAACCTGCGCAAAAACGTCATCCGGTCCGTATTACGTGGTGCCCGGCCACTGTTCGCTTCCCGCCGGCTGGGTATTGC
CGGCCGTCGAGTCCTGCTGGCGACGCTGACGGCCGGCGCGCGCGCCCCCAAGGGCACCCGCTTTCAGCGCGTCAGCATCG
CCGGTGTCCCGGTCCAGCGGGTGCAACCCCCCCATGCGGCAACCAGCGGGACGCTGATCTACCTGCACGGCGGTGCCTAC
GCCCTGGGCAGCGCCCGGGGCTACCGCGGCCTGGCCGCCCAGCTCGCGGCGGCGGCCGGAATGACGGCGCTGGTCCCCGA
CTACACCCGCGCACCGCACGCCCACTATCCAGTGGCCCTCGAAGAGATGGCTGCGGTGTACACCCGCTTGCTCGACGACG
GGCTCGACCCGAAAACGACCGTCATCGCCGGTGATTCGGCTGGCGGAGGGTTGACCCTGGCGCTGGCCATGGCGCTGCGC
GATCGCGGCATCCAGGCCCCGGCCGCACTCGGCCTGATCTGCCCGTGGGCCGATCTCGCCGTCGACATCGAAGCGACGCG
ACCGGCGCTGCGCGATCCGCTCATTCTTCCGTCGATGTGCACCGAATGGGCGCCGCGCTACGTAGGGTCCTCCGATCCGC
GGCTGCCCGGTATCTCCCCGGTCTACGGCGACATGAGCGGCCTGCCGCCCATCGTCATGCAGACCGCGGGCGACGATCCG
ATCTGCGTCGACGCGGACAAGATCGAAACCGCCTGCGCCGCTTCGAAAACAAGCATCGAGCATCGCCGGTTCGCGGGCAT
GTGGCACGACTTCCATCTGCAGGTCGGTCTGCTCCCCGAAGCCCGCGACGCGATCGCCGACCTCGGGGCAAGGCTGCGCG
GCCACCTCCACCAATCGCAGGGACAACCACGGGGAGTAGTCAAATGA

Upstream 100 bases:

>100_bases
ACTACGAGAAGGACGCCAAGATCCTGCTCGAAGACCCCATCGATGACGGCGTGCTGCACTTCGCCGCAGCGGCCCAAGAC
CACGCGGCGGCCTGAGCATC

Downstream 100 bases:

>100_bases
GCTCATTCGAAGGCAAGGTCGCCGTCATCACCGGGGCCGGCTCGGGCATCGGCAGAGCGTTGGCACTCAACCTCTCCGAG
AAGCGCGCAAAGCTTGCCCT

Product: putative acetyl-hydrolase/esterase lipR

Products: alcohol; a carboxylate [C]

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNLRKNVIRSVLRGARPLFASRRLGIAGRRVLLATLTAGARAPKGTRFQRVSIAGVPVQRVQPPHAATSGTLIYLHGGAY
ALGSARGYRGLAAQLAAAAGMTALVPDYTRAPHAHYPVALEEMAAVYTRLLDDGLDPKTTVIAGDSAGGGLTLALAMALR
DRGIQAPAALGLICPWADLAVDIEATRPALRDPLILPSMCTEWAPRYVGSSDPRLPGISPVYGDMSGLPPIVMQTAGDDP
ICVDADKIETACAASKTSIEHRRFAGMWHDFHLQVGLLPEARDAIADLGARLRGHLHQSQGQPRGVVK

Sequences:

>Translated_308_residues
MNLRKNVIRSVLRGARPLFASRRLGIAGRRVLLATLTAGARAPKGTRFQRVSIAGVPVQRVQPPHAATSGTLIYLHGGAY
ALGSARGYRGLAAQLAAAAGMTALVPDYTRAPHAHYPVALEEMAAVYTRLLDDGLDPKTTVIAGDSAGGGLTLALAMALR
DRGIQAPAALGLICPWADLAVDIEATRPALRDPLILPSMCTEWAPRYVGSSDPRLPGISPVYGDMSGLPPIVMQTAGDDP
ICVDADKIETACAASKTSIEHRRFAGMWHDFHLQVGLLPEARDAIADLGARLRGHLHQSQGQPRGVVK
>Mature_308_residues
MNLRKNVIRSVLRGARPLFASRRLGIAGRRVLLATLTAGARAPKGTRFQRVSIAGVPVQRVQPPHAATSGTLIYLHGGAY
ALGSARGYRGLAAQLAAAAGMTALVPDYTRAPHAHYPVALEEMAAVYTRLLDDGLDPKTTVIAGDSAGGGLTLALAMALR
DRGIQAPAALGLICPWADLAVDIEATRPALRDPLILPSMCTEWAPRYVGSSDPRLPGISPVYGDMSGLPPIVMQTAGDDP
ICVDADKIETACAASKTSIEHRRFAGMWHDFHLQVGLLPEARDAIADLGARLRGHLHQSQGQPRGVVK

Specific function: This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1786682, Length=236, Percent_Identity=26.6949152542373, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567059, Length=288, Percent_Identity=25.3472222222222, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI72001146, Length=141, Percent_Identity=31.2056737588652, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 32587; Mature: 32587

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRKNVIRSVLRGARPLFASRRLGIAGRRVLLATLTAGARAPKGTRFQRVSIAGVPVQR
CCHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCEEEEEEECCCHHH
VQPPHAATSGTLIYLHGGAYALGSARGYRGLAAQLAAAAGMTALVPDYTRAPHAHYPVAL
CCCCCCCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHH
EEMAAVYTRLLDDGLDPKTTVIAGDSAGGGLTLALAMALRDRGIQAPAALGLICPWADLA
HHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHEECCCHHHE
VDIEATRPALRDPLILPSMCTEWAPRYVGSSDPRLPGISPVYGDMSGLPPIVMQTAGDDP
EEEHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
ICVDADKIETACAASKTSIEHRRFAGMWHDFHLQVGLLPEARDAIADLGARLRGHLHQSQ
EEECHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCC
GQPRGVVK
CCCCCCCC
>Mature Secondary Structure
MNLRKNVIRSVLRGARPLFASRRLGIAGRRVLLATLTAGARAPKGTRFQRVSIAGVPVQR
CCHHHHHHHHHHHCCCHHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCEEEEEEECCCHHH
VQPPHAATSGTLIYLHGGAYALGSARGYRGLAAQLAAAAGMTALVPDYTRAPHAHYPVAL
CCCCCCCCCCEEEEEECCEEEECCCCCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHH
EEMAAVYTRLLDDGLDPKTTVIAGDSAGGGLTLALAMALRDRGIQAPAALGLICPWADLA
HHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHEECCCHHHE
VDIEATRPALRDPLILPSMCTEWAPRYVGSSDPRLPGISPVYGDMSGLPPIVMQTAGDDP
EEEHHCCCHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
ICVDADKIETACAASKTSIEHRRFAGMWHDFHLQVGLLPEARDAIADLGARLRGHLHQSQ
EEECHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHCC
GQPRGVVK
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2066341 [H]