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The map label for this gene is ppk

Identifier: 121638865

GI number: 121638865

Start: 3294368

End: 3296596

Strand: Direct

Name: ppk

Synonym: BCG_3005

Alternate gene names: 121638865

Gene position: 3294368-3296596 (Clockwise)

Preceding gene: 121638864

Following gene: 121638866

Centisome position: 75.31

GC content: 63.39

Gene sequence:

>2229_bases
ATGATGAGCAATGATCGCAAGGTGACCGAAATCGAAAACAGTCCCGTCACAGAGGTGCGGCCAGAGGAGCATGCGTGGTA
TCCAGACGACTCGGCGCTGGCGGCACCGCCCGCTGCCACCCCCGCCGCGATTAGCGACCAGCTACCCTCGGATCGCTACC
TGAACCGGGAGCTGAGTTGGCTGGACTTCAACGCGCGCGTGCTTGCCCTGGCCGCCGATAAGTCGATGCCATTGCTCGAG
CGCGCCAAGTTTCTGGCAATCTTCGCGTCCAATCTCGACGAGTTCTACATGGTCCGGGTGGCCGGCCTCAAACGCCGCGA
CGAGATGGGGTTGTCGGTGCGCTCCGCCGACGGTCTAACACCGCGCGAACAACTAGGCCGGATCGGCGAGCAGACTCAAC
AGCTCGCCAGCCGGCATGCCCGGGTGTTCCTCGATTCGGTGCTACCCGCGCTCGGCGAGGAAGGCATCTACATCGTCACC
TGGGCCGATTTGGATCAGGCTGAGCGCGACCGATTGTCGACCTATTTCAACGAACAGGTCTTCCCCGTCCTGACCCCGCT
GGCCGTCGATCCCGCCCACCCGTTCCCGTTTGTCAGCGGGTTGAGCTTGAACCTGGCGGTCACGGTACGCCAACCTGAAG
ACGGCACCCAGCATTTCGCGAGGGTCAAGGTGCCCGACAACGTCGACCGCTTCGTCGAACTCGCTGCACGTGAGGCCAGC
GAGGAAGCTGCGGGGACCGAAGGCCGGACCGCGCTGCGGTTCCTGCCGATGGAGGAGCTGATCGCGGCCTTCCTTCCGGT
GCTTTTCCCGGGTATGGAAATCGTCGAGCACCACGCATTTCGCATCACTCGCAACGCTGACTTCGAGGTTGAAGAGGATC
GCGACGAGGACCTACTGCAGGCGCTCGAGCGAGAACTGGCCCGCCGCCGGTTCGGTTCACCGGTGCGACTCGAGATCGCA
GACGACATGACCGAGAGCATGCTGGAGTTGCTGCTTCGCGAACTCGACGTGCATCCCGGTGATGTCATCGAAGTGCCCGG
GCTGCTCGACCTATCGTCGTTGTGGCAGATCTACGCCGTGGACCGCCCGACGCTTAAGGATCGGACATTCGTCCCAGCTA
CCCATCCCGCCTTCGCCGAGCGGGAAACACCCAAAAGCATCTTCGCGACGCTGCGCGAAGGCGATGTGCTGGTTCACCAT
CCGTATGACTCGTTCTCCACCAGCGTGCAGCGATTCATCGAACAGGCCGCGGCCGACCCCAACGTGCTGGCGATCAAACA
GACGCTGTACCGCACCTCCGGCGACTCGCCGATCGTCCGGGCGCTGATCGACGCCGCCGAAGCCGGAAAGCAAGTGGTGG
CACTGGTCGAGATCAAGGCACGCTTCGACGAACAGGCCAACATCGCCTGGGCGCGCGCACTAGAACAAGCCGGCGTGCAT
GTGGCGTACGGGCTCGTCGGGCTCAAGACGCACTGCAAGACCGCCTTGGTGGTGCGCCGCGAAGGTCCGACAATCCGGCG
GTACTGCCATGTCGGCACCGGCAATTACAACAGCAAGACAGCACGACTCTACGAGGACGTCGGACTGCTGACCGCTGCAC
CCGATATCGGCGCCGACTTGACCGACTTGTTCAATTCGCTCACCGGCTACTCACGCAAGTTGTCCTACCGCAACTTGTTG
GTGGCCCCGCACGGAATCCGCGCCGGCATCATTGACCGCGTCGAGCGGGAGGTCGCGGCGCACCGTGCAGAGGGTGCCCA
CAACGGCAAAGGCCGCATCCGACTCAAGATGAATGCCCTTGTTGATGAGCAGGTCATCGATGCGCTGTACCGCGCGTCGC
GAGCCGGTGTGCGGATCGAGGTGGTGGTACGCGGCATCTGCGCGCTGCGTCCAGGTGCGCAGGGCATTTCGGAAAACATC
ATCGTGCGCTCGATTCTCGGCCGCTTCCTCGAGCACTCGCGGATCCTCCATTTCCGTGCCATCGACGAGTTCTGGATCGG
CAGCGCCGACATGATGCACCGCAACCTCGACCGGCGAGTCGAGGTTATGGCTCAAGTCAAAAACCCGAGGCTGACCGCGC
AGCTGGACGAATTGTTCGAATCCGCACTGGACCCGTGCACCCGGTGCTGGGAGCTCGGGCCCGACGGGCAGTGGACCGCG
TCGCCGCAAGAAGGCCATAGCGTGCGCGACCATCAGGAATCGCTGATGGAACGGCACCGCAGCCCCTGA

Upstream 100 bases:

>100_bases
CATCGTTGACCGGGACGGGGCAACGCCGGCGAGGCATCCAGGGGGTGAACGGCAGACCAACGGCGAACGGATGCCTGCCG
AGTGCTGGCAACCCCACCCA

Downstream 100 bases:

>100_bases
CACTGCGTGGTGATTCCCGCTGCTGCACCGACCACATCCACGACCGCGAGCAGCCTGGCCGAATTGACCTGCAGGAGTTG
AGGTGTCGATCCAGAACTCG

Product: polyphosphate kinase

Products: NA

Alternate protein names: ATP-polyphosphate phosphotransferase; Polyphosphoric acid kinase

Number of amino acids: Translated: 742; Mature: 742

Protein sequence:

>742_residues
MMSNDRKVTEIENSPVTEVRPEEHAWYPDDSALAAPPAATPAAISDQLPSDRYLNRELSWLDFNARVLALAADKSMPLLE
RAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPREQLGRIGEQTQQLASRHARVFLDSVLPALGEEGIYIVT
WADLDQAERDRLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGTQHFARVKVPDNVDRFVELAAREAS
EEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAFRITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIA
DDMTESMLELLLRELDVHPGDVIEVPGLLDLSSLWQIYAVDRPTLKDRTFVPATHPAFAERETPKSIFATLREGDVLVHH
PYDSFSTSVQRFIEQAAADPNVLAIKQTLYRTSGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIAWARALEQAGVH
VAYGLVGLKTHCKTALVVRREGPTIRRYCHVGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLSYRNLL
VAPHGIRAGIIDRVEREVAAHRAEGAHNGKGRIRLKMNALVDEQVIDALYRASRAGVRIEVVVRGICALRPGAQGISENI
IVRSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEVMAQVKNPRLTAQLDELFESALDPCTRCWELGPDGQWTA
SPQEGHSVRDHQESLMERHRSP

Sequences:

>Translated_742_residues
MMSNDRKVTEIENSPVTEVRPEEHAWYPDDSALAAPPAATPAAISDQLPSDRYLNRELSWLDFNARVLALAADKSMPLLE
RAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPREQLGRIGEQTQQLASRHARVFLDSVLPALGEEGIYIVT
WADLDQAERDRLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGTQHFARVKVPDNVDRFVELAAREAS
EEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAFRITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIA
DDMTESMLELLLRELDVHPGDVIEVPGLLDLSSLWQIYAVDRPTLKDRTFVPATHPAFAERETPKSIFATLREGDVLVHH
PYDSFSTSVQRFIEQAAADPNVLAIKQTLYRTSGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIAWARALEQAGVH
VAYGLVGLKTHCKTALVVRREGPTIRRYCHVGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLSYRNLL
VAPHGIRAGIIDRVEREVAAHRAEGAHNGKGRIRLKMNALVDEQVIDALYRASRAGVRIEVVVRGICALRPGAQGISENI
IVRSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEVMAQVKNPRLTAQLDELFESALDPCTRCWELGPDGQWTA
SPQEGHSVRDHQESLMERHRSP
>Mature_742_residues
MMSNDRKVTEIENSPVTEVRPEEHAWYPDDSALAAPPAATPAAISDQLPSDRYLNRELSWLDFNARVLALAADKSMPLLE
RAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLTPREQLGRIGEQTQQLASRHARVFLDSVLPALGEEGIYIVT
WADLDQAERDRLSTYFNEQVFPVLTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGTQHFARVKVPDNVDRFVELAAREAS
EEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAFRITRNADFEVEEDRDEDLLQALERELARRRFGSPVRLEIA
DDMTESMLELLLRELDVHPGDVIEVPGLLDLSSLWQIYAVDRPTLKDRTFVPATHPAFAERETPKSIFATLREGDVLVHH
PYDSFSTSVQRFIEQAAADPNVLAIKQTLYRTSGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIAWARALEQAGVH
VAYGLVGLKTHCKTALVVRREGPTIRRYCHVGTGNYNSKTARLYEDVGLLTAAPDIGADLTDLFNSLTGYSRKLSYRNLL
VAPHGIRAGIIDRVEREVAAHRAEGAHNGKGRIRLKMNALVDEQVIDALYRASRAGVRIEVVVRGICALRPGAQGISENI
IVRSILGRFLEHSRILHFRAIDEFWIGSADMMHRNLDRRVEVMAQVKNPRLTAQLDELFESALDPCTRCWELGPDGQWTA
SPQEGHSVRDHQESLMERHRSP

Specific function: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)

COG id: COG0855

COG function: function code P; Polyphosphate kinase

Gene ontology:

Cell location: Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polyphosphate kinase family

Homologues:

Organism=Escherichia coli, GI1788847, Length=660, Percent_Identity=33.9393939393939, Blast_Score=358, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPK_MYCBO (P65769)

Other databases:

- EMBL:   BX248344
- RefSeq:   NP_856653.1
- ProteinModelPortal:   P65769
- SMR:   P65769
- EnsemblBacteria:   EBMYCT00000016639
- GeneID:   1093158
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb3008
- GeneTree:   EBGT00050000016805
- HOGENOM:   HBG341268
- OMA:   MPSETIA
- ProtClustDB:   PRK05443
- BioCyc:   MBOV233413:MB3008-MONOMER
- BRENDA:   2.7.4.1
- HAMAP:   MF_00347
- InterPro:   IPR003414
- PIRSF:   PIRSF015589
- TIGRFAMs:   TIGR03705

Pfam domain/function: PF02503 PP_kinase

EC number: =2.7.4.1

Molecular weight: Translated: 83040; Mature: 83040

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: ACT_SITE 491-491 ACT_SITE 510-510

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSNDRKVTEIENSPVTEVRPEEHAWYPDDSALAAPPAATPAAISDQLPSDRYLNRELSW
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHCCCCCE
LDFNARVLALAADKSMPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLT
EECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCEEECCCCCC
PREQLGRIGEQTQQLASRHARVFLDSVLPALGEEGIYIVTWADLDQAERDRLSTYFNEQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCH
FPVLTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGTQHFARVKVPDNVDRFVELAAREAS
HHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHH
EEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAFRITRNADFEVEEDRDEDLLQ
HHHCCCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCCCCCCCHHHHH
ALERELARRRFGSPVRLEIADDMTESMLELLLRELDVHPGDVIEVPGLLDLSSLWQIYAV
HHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHEEEC
DRPTLKDRTFVPATHPAFAERETPKSIFATLREGDVLVHHPYDSFSTSVQRFIEQAAADP
CCCCCCCCEECCCCCCCHHCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCC
NVLAIKQTLYRTSGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIAWARALEQAGVH
CEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCHHHHHHHHHHCCCE
VAYGLVGLKTHCKTALVVRREGPTIRRYCHVGTGNYNSKTARLYEDVGLLTAAPDIGADL
EEHHHHHHHHHCCEEEEEECCCCCEEHEEEECCCCCCCHHHHHHHHCCCEEECCCCCCCH
TDLFNSLTGYSRKLSYRNLLVAPHGIRAGIIDRVEREVAAHRAEGAHNGKGRIRLKMNAL
HHHHHHHHCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHH
VDEQVIDALYRASRAGVRIEVVVRGICALRPGAQGISENIIVRSILGRFLEHSRILHFRA
HHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEE
IDEFWIGSADMMHRNLDRRVEVMAQVKNPRLTAQLDELFESALDPCTRCWELGPDGQWTA
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SPQEGHSVRDHQESLMERHRSP
CCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSNDRKVTEIENSPVTEVRPEEHAWYPDDSALAAPPAATPAAISDQLPSDRYLNRELSW
CCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHCCCCCE
LDFNARVLALAADKSMPLLERAKFLAIFASNLDEFYMVRVAGLKRRDEMGLSVRSADGLT
EECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHCCCEEECCCCCC
PREQLGRIGEQTQQLASRHARVFLDSVLPALGEEGIYIVTWADLDQAERDRLSTYFNEQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCH
FPVLTPLAVDPAHPFPFVSGLSLNLAVTVRQPEDGTQHFARVKVPDNVDRFVELAAREAS
HHHHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHH
EEAAGTEGRTALRFLPMEELIAAFLPVLFPGMEIVEHHAFRITRNADFEVEEDRDEDLLQ
HHHCCCCCCCEEEECCHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCCCCCCCHHHHH
ALERELARRRFGSPVRLEIADDMTESMLELLLRELDVHPGDVIEVPGLLDLSSLWQIYAV
HHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHEEEC
DRPTLKDRTFVPATHPAFAERETPKSIFATLREGDVLVHHPYDSFSTSVQRFIEQAAADP
CCCCCCCCEECCCCCCCHHCCCCHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHCCCC
NVLAIKQTLYRTSGDSPIVRALIDAAEAGKQVVALVEIKARFDEQANIAWARALEQAGVH
CEEHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEHHHHCCCCCHHHHHHHHHHCCCE
VAYGLVGLKTHCKTALVVRREGPTIRRYCHVGTGNYNSKTARLYEDVGLLTAAPDIGADL
EEHHHHHHHHHCCEEEEEECCCCCEEHEEEECCCCCCCHHHHHHHHCCCEEECCCCCCCH
TDLFNSLTGYSRKLSYRNLLVAPHGIRAGIIDRVEREVAAHRAEGAHNGKGRIRLKMNAL
HHHHHHHHCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHH
VDEQVIDALYRASRAGVRIEVVVRGICALRPGAQGISENIIVRSILGRFLEHSRILHFRA
HHHHHHHHHHHHHCCCCEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEE
IDEFWIGSADMMHRNLDRRVEVMAQVKNPRLTAQLDELFESALDPCTRCWELGPDGQWTA
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SPQEGHSVRDHQESLMERHRSP
CCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972