Click here to switch to the map view.

The map label for this gene is scoA

Identifier: 121638386

GI number: 121638386

Start: 2782920

End: 2783666

Strand: Reverse

Name: scoA

Synonym: BCG_2524c

Alternate gene names: 121638386

Gene position: 2783666-2782920 (Counterclockwise)

Preceding gene: 121638387

Following gene: 121638385

Centisome position: 63.63

GC content: 65.46

Gene sequence:

>747_bases
ATGGACAAGGTGGTGGCCACCGCCGCGGAGGCGGTCGCAGACATAGCCAACGGGTCGTCGCTTGCGGTTGGTGGATTCGG
GCTTTGCGGCATCCCCGAAGCACTGATCGCAGCGTTGGTGGATAGCGGTGTCACCGACCTGGAAACAGTCTCGAACAACT
GCGGAATCGACGGTGTTGGTCTGGGACTATTGTTGCAACACAAGCGAATTCGCCGGACAGTCTCCTCCTACGTGGGGGAG
AACAAGGAGTTCGCCCGCCAGTTCCTCGCGGGCGAGCTCGAGGTGGAACTGACCCCGCAGGGCACGCTGGCCGAGCGGTT
GCGGGCCGGAGGGATGGGCATACCGGCCTTCTATACACCGGCAGGGGTCGGTACCCAGGTCGCCGACGGCGGGTTGCCGT
GGCGCTACGACGCCTCGGGCGGGGTGGCGGTGGTGTCGCCGGCCAAGGAGACTCGGGAGTTCGATGGTGTCACCTATGTC
CTCGAGCGGGGGATCCGGACCGACTTCGCACTGGTGCATGCCTGGCAGGGGGACCGGCACGGCAACCTGATGTACCGCCA
CGCCGCGGCCAACTTCAACCCGGAGTGCGCATCCGCAGGCAGGATCACGATCGCCGAGGTCGAGCACTTGGTCGAGCCGG
GTGAGATCGACCCTGCCACCGTACACACCCCGGGCGTGTTTGTGCACCGGGTGGTTCATGTGCCCAACCCCGCCAAGAAG
ATCGAGAGGGAGACGGTGCGGCAATGA

Upstream 100 bases:

>100_bases
CTCCGCGGCCAACAGTGAGGTCCCTAGACGCACCGCGGGGGCAATGGTATTCTCACCTCAGTTAATGATAATTAACTGAA
ATGCTAGGAGGCTCTGCGGT

Downstream 100 bases:

>100_bases
GCGCCCCGGGCTGGAGCCGAGACGAGATGGCCGCACGGGTGGCCGCGGAGTTCGAAGACGGTCAGTATGTCAACCTTGGC
ATCGGCATGCCCACCCTGAT

Product: putative succinyl-CoA:3-ketoacid-coenzyme A transferase subunit alpha scoA

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MDKVVATAAEAVADIANGSSLAVGGFGLCGIPEALIAALVDSGVTDLETVSNNCGIDGVGLGLLLQHKRIRRTVSSYVGE
NKEFARQFLAGELEVELTPQGTLAERLRAGGMGIPAFYTPAGVGTQVADGGLPWRYDASGGVAVVSPAKETREFDGVTYV
LERGIRTDFALVHAWQGDRHGNLMYRHAAANFNPECASAGRITIAEVEHLVEPGEIDPATVHTPGVFVHRVVHVPNPAKK
IERETVRQ

Sequences:

>Translated_248_residues
MDKVVATAAEAVADIANGSSLAVGGFGLCGIPEALIAALVDSGVTDLETVSNNCGIDGVGLGLLLQHKRIRRTVSSYVGE
NKEFARQFLAGELEVELTPQGTLAERLRAGGMGIPAFYTPAGVGTQVADGGLPWRYDASGGVAVVSPAKETREFDGVTYV
LERGIRTDFALVHAWQGDRHGNLMYRHAAANFNPECASAGRITIAEVEHLVEPGEIDPATVHTPGVFVHRVVHVPNPAKK
IERETVRQ
>Mature_248_residues
MDKVVATAAEAVADIANGSSLAVGGFGLCGIPEALIAALVDSGVTDLETVSNNCGIDGVGLGLLLQHKRIRRTVSSYVGE
NKEFARQFLAGELEVELTPQGTLAERLRAGGMGIPAFYTPAGVGTQVADGGLPWRYDASGGVAVVSPAKETREFDGVTYV
LERGIRTDFALVHAWQGDRHGNLMYRHAAANFNPECASAGRITIAEVEHLVEPGEIDPATVHTPGVFVHRVVHVPNPAKK
IERETVRQ

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family

Homologues:

Organism=Homo sapiens, GI4557817, Length=246, Percent_Identity=54.4715447154472, Blast_Score=281, Evalue=4e-76,
Organism=Homo sapiens, GI11545841, Length=244, Percent_Identity=52.8688524590164, Blast_Score=253, Evalue=1e-67,
Organism=Escherichia coli, GI1788551, Length=232, Percent_Identity=38.3620689655172, Blast_Score=166, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI17531517, Length=243, Percent_Identity=56.3786008230453, Blast_Score=284, Evalue=3e-77,
Organism=Drosophila melanogaster, GI21358325, Length=241, Percent_Identity=48.9626556016597, Blast_Score=253, Evalue=9e-68,
Organism=Drosophila melanogaster, GI24655794, Length=241, Percent_Identity=48.9626556016597, Blast_Score=253, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SCOA_MYCBO (P63649)

Other databases:

- EMBL:   BX248342
- RefSeq:   NP_856177.1
- ProteinModelPortal:   P63649
- SMR:   P63649
- EnsemblBacteria:   EBMYCT00000014870
- GeneID:   1090568
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2532c
- GeneTree:   EBGT00050000016109
- HOGENOM:   HBG288750
- OMA:   VHRIVLN
- ProtClustDB:   CLSK872071
- BioCyc:   MBOV233413:MB2532C-MONOMER
- BRENDA:   2.8.3.5
- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163
- PANTHER:   PTHR13707
- SMART:   SM00882
- TIGRFAMs:   TIGR02429

Pfam domain/function: PF01144 CoA_trans

EC number: =2.8.3.5

Molecular weight: Translated: 26276; Mature: 26276

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVVATAAEAVADIANGSSLAVGGFGLCGIPEALIAALVDSGVTDLETVSNNCGIDGVG
CCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHH
LGLLLQHKRIRRTVSSYVGENKEFARQFLAGELEVELTPQGTLAERLRAGGMGIPAFYTP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCEECC
AGVGTQVADGGLPWRYDASGGVAVVSPAKETREFDGVTYVLERGIRTDFALVHAWQGDRH
CCCCCCCCCCCCCEEEECCCCEEEECCCHHHHHHCCHHHHHHCCCCCCEEEEEEECCCCC
GNLMYRHAAANFNPECASAGRITIAEVEHLVEPGEIDPATVHTPGVFVHRVVHVPNPAKK
CCEEEEEECCCCCCCCCCCCCEEHHHHHHHCCCCCCCCCEEECCCCEEEEEEECCCHHHH
IERETVRQ
HHHHHHCC
>Mature Secondary Structure
MDKVVATAAEAVADIANGSSLAVGGFGLCGIPEALIAALVDSGVTDLETVSNNCGIDGVG
CCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHH
LGLLLQHKRIRRTVSSYVGENKEFARQFLAGELEVELTPQGTLAERLRAGGMGIPAFYTP
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHHCCCCCCCEECC
AGVGTQVADGGLPWRYDASGGVAVVSPAKETREFDGVTYVLERGIRTDFALVHAWQGDRH
CCCCCCCCCCCCCEEEECCCCEEEECCCHHHHHHCCHHHHHHCCCCCCEEEEEEECCCCC
GNLMYRHAAANFNPECASAGRITIAEVEHLVEPGEIDPATVHTPGVFVHRVVHVPNPAKK
CCEEEEEECCCCCCCCCCCCCEEHHHHHHHCCCCCCCCCEEECCCCEEEEEEECCCHHHH
IERETVRQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972