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The map label for this gene is mbtH

Identifier: 121638256

GI number: 121638256

Start: 2621237

End: 2621452

Strand: Reverse

Name: mbtH

Synonym: BCG_2391c

Alternate gene names: 121638256

Gene position: 2621452-2621237 (Counterclockwise)

Preceding gene: 121638257

Following gene: 121638255

Centisome position: 59.93

GC content: 63.89

Gene sequence:

>216_bases
GTGAGCACCAATCCTTTCGATGACGACAACGGCGCATTCTTCGTGCTGGTCAACGACGAAGACCAGCACAGCCTGTGGCC
GGTGTTCGCCGATATCCCGGCCGGCTGGCGCGTGGTGCACGGCGAAGCCAGCCGTGCCGCCTGCCTGGACTACGTGGAAA
AGAACTGGACCGATCTGCGGCCGAAGAGCCTGCGTGACGCCATGGCCGAGGACTGA

Upstream 100 bases:

>100_bases
CCCGGGTTCCCCAACCTGAGCTGCCTCGGCTTGTTGTCGGACCGGGTGCTCGGCGCCGGCATCTTTACGCCGACCAAACA
CAACGACACAAGGAGAAGCG

Downstream 100 bases:

>100_bases
CCGCTCGCTCACAGCTACGACACAGACTTGCCCGGCGCGTGCACCGGTAGTTTGAACCAAACGCACAATCGACGGGCAAA
CGAACGGAAGAACACAACCA

Product: putative protein mbtH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 71; Mature: 70

Protein sequence:

>71_residues
MSTNPFDDDNGAFFVLVNDEDQHSLWPVFADIPAGWRVVHGEASRAACLDYVEKNWTDLRPKSLRDAMAED

Sequences:

>Translated_71_residues
MSTNPFDDDNGAFFVLVNDEDQHSLWPVFADIPAGWRVVHGEASRAACLDYVEKNWTDLRPKSLRDAMAED
>Mature_70_residues
STNPFDDDNGAFFVLVNDEDQHSLWPVFADIPAGWRVVHGEASRAACLDYVEKNWTDLRPKSLRDAMAED

Specific function: Could be involved in mycobactin synthesis

COG id: COG3251

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To M.tuberculosis mbtH

Homologues:

Organism=Escherichia coli, GI87081760, Length=62, Percent_Identity=43.5483870967742, Blast_Score=65, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MBTH_MYCBO (P59965)

Other databases:

- EMBL:   BX248342
- RefSeq:   NP_856047.1
- ProteinModelPortal:   P59965
- SMR:   P59965
- EnsemblBacteria:   EBMYCT00000015833
- GeneID:   1094386
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb2398c
- GeneTree:   EBGT00050000016148
- HOGENOM:   HBG451772
- OMA:   HSLWPSF
- ProtClustDB:   CLSK791810
- BioCyc:   MBOV233413:MB2398C-MONOMER
- InterPro:   IPR015166
- InterPro:   IPR005153
- Gene3D:   G3DSA:3.90.820.10
- SMART:   SM00923

Pfam domain/function: PF03621 MbtH

EC number: NA

Molecular weight: Translated: 8054; Mature: 7923

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNPFDDDNGAFFVLVNDEDQHSLWPVFADIPAGWRVVHGEASRAACLDYVEKNWTDLR
CCCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCC
PKSLRDAMAED
CHHHHHHCCCC
>Mature Secondary Structure 
STNPFDDDNGAFFVLVNDEDQHSLWPVFADIPAGWRVVHGEASRAACLDYVEKNWTDLR
CCCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCEEEEECCCCHHHHHHHHHCCCCCCC
PKSLRDAMAED
CHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972