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The map label for this gene is cysE

Identifier: 121638222

GI number: 121638222

Start: 2586828

End: 2587517

Strand: Direct

Name: cysE

Synonym: BCG_2357

Alternate gene names: 121638222

Gene position: 2586828-2587517 (Clockwise)

Preceding gene: 121638221

Following gene: 121638223

Centisome position: 59.13

GC content: 69.28

Gene sequence:

>690_bases
ATGCTGACGGCCATGCGGGGCGACATCCGAGCAGCCCGGGAGCGGGATCCGGCGGCCCCTACCGCGCTGGAAGTCATCTT
CTGCTACCCGGGCGTGCACGCCGTGTGGGGCCACCGCCTCGCCCACTGGCTGTGGCAGCGTGGCGCCAGGCTGCTCGCGC
GGGCAGCTGCCGAATTCACTCGCATCCTGACCGGTGTAGATATCCACCCCGGTGCCGTCATCGGTGCTCGCGTGTTCATC
GACCACGCGACCGGCGTGGTGATCGGAGAAACCGCGGAGGTCGGCGACGACGTCACGATCTATCACGGCGTCACTCTCGG
CGGCAGTGGCATGGTTGGCGGGAAACGCCATCCCACCGTCGGTGACCGCGTGATCATCGGCGCCGGGGCCAAGGTCCTCG
GTCCGATCAAGATCGGCGAGGACAGCCGGATCGGCGCCAATGCCGTCGTGGTCAAGCCCGTCCCGCCGAGCGCGGTGGTG
GTCGGGGTGCCCGGGCAGGTCATCGGCCAAAGCCAGCCCAGTCCCGGCGGCCCGTTTGATTGGAGGCTGCCCGATCTCGT
GGGAGCCAGCCTCGATTCGCTGCTCACCAGGGTGGCCAGGCTGGAGGCCCTCGGCGGCGGCCCGCAAGCAGCAGGAGTCA
TCCGGCCACCCGAAGCCGGGATATGGCACGGCGAGGACTTCTCGATCTGA

Upstream 100 bases:

>100_bases
CCGGCCAGAGAACGCCGGGAAGCTAATCGTCGTAGTGCTCCCCGACTTCGGCGAACGATATCTGAGCACACCGTTGTTCG
CCGACGTGGCTGACTAAGCC

Downstream 100 bases:

>100_bases
GGCAATACCCGGCCGCCGACAATGCCTTCTTCGGCGCCGCCCACCGACGCGCATCATCGGCTGCTAGCCCCCGCACCGGG
TTCCGTCCTCGCCGAATTCA

Product: putative serine acetyltransferase cysE

Products: NA

Alternate protein names: SAT

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQRGARLLARAAAEFTRILTGVDIHPGAVIGARVFI
DHATGVVIGETAEVGDDVTIYHGVTLGGSGMVGGKRHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVVKPVPPSAVV
VGVPGQVIGQSQPSPGGPFDWRLPDLVGASLDSLLTRVARLEALGGGPQAAGVIRPPEAGIWHGEDFSI

Sequences:

>Translated_229_residues
MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQRGARLLARAAAEFTRILTGVDIHPGAVIGARVFI
DHATGVVIGETAEVGDDVTIYHGVTLGGSGMVGGKRHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVVKPVPPSAVV
VGVPGQVIGQSQPSPGGPFDWRLPDLVGASLDSLLTRVARLEALGGGPQAAGVIRPPEAGIWHGEDFSI
>Mature_229_residues
MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQRGARLLARAAAEFTRILTGVDIHPGAVIGARVFI
DHATGVVIGETAEVGDDVTIYHGVTLGGSGMVGGKRHPTVGDRVIIGAGAKVLGPIKIGEDSRIGANAVVVKPVPPSAVV
VGVPGQVIGQSQPSPGGPFDWRLPDLVGASLDSLLTRVARLEALGGGPQAAGVIRPPEAGIWHGEDFSI

Specific function: Catalyzes the acetylation of serine by acetyl-CoA to produce O-acetylserine (OAS)

COG id: COG1045

COG function: function code E; Serine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1790035, Length=170, Percent_Identity=45.2941176470588, Blast_Score=156, Evalue=9e-40,
Organism=Escherichia coli, GI1788371, Length=142, Percent_Identity=37.3239436619718, Blast_Score=74, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSE_MYCTU (P95231)

Other databases:

- EMBL:   BX842579
- PIR:   H70660
- RefSeq:   NP_216851.1
- ProteinModelPortal:   P95231
- SMR:   P95231
- EnsemblBacteria:   EBMYCT00000000047
- GeneID:   886012
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv2335
- TubercuList:   Rv2335
- GeneTree:   EBGT00050000017947
- HOGENOM:   HBG754554
- OMA:   YSTVINY
- ProtClustDB:   CLSK791792
- GO:   GO:0005737
- InterPro:   IPR018357
- InterPro:   IPR005881
- InterPro:   IPR011004
- PIRSF:   PIRSF000441
- TIGRFAMs:   TIGR01172

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.30

Molecular weight: Translated: 23771; Mature: 23771

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQRGARLLARAAAEFT
CCCCCCCCHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILTGVDIHPGAVIGARVFIDHATGVVIGETAEVGDDVTIYHGVTLGGSGMVGGKRHPTV
HHHHCCCCCCCCEEEEEEEEECCCCEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCCC
GDRVIIGAGAKVLGPIKIGEDSRIGANAVVVKPVPPSAVVVGVPGQVIGQSQPSPGGPFD
CCEEEEECCCEEEEEEEECCCCCCCCCEEEEECCCCCEEEEECCHHHHCCCCCCCCCCCC
WRLPDLVGASLDSLLTRVARLEALGGGPQAAGVIRPPEAGIWHGEDFSI
CCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MLTAMRGDIRAARERDPAAPTALEVIFCYPGVHAVWGHRLAHWLWQRGARLLARAAAEFT
CCCCCCCCHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILTGVDIHPGAVIGARVFIDHATGVVIGETAEVGDDVTIYHGVTLGGSGMVGGKRHPTV
HHHHCCCCCCCCEEEEEEEEECCCCEEEECCCCCCCCEEEEEEEEECCCCCCCCCCCCCC
GDRVIIGAGAKVLGPIKIGEDSRIGANAVVVKPVPPSAVVVGVPGQVIGQSQPSPGGPFD
CCEEEEECCCEEEEEEEECCCCCCCCCEEEEECCCCCEEEEECCHHHHCCCCCCCCCCCC
WRLPDLVGASLDSLLTRVARLEALGGGPQAAGVIRPPEAGIWHGEDFSI
CCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230