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The map label for this gene is rocD1 [H]

Identifier: 121638208

GI number: 121638208

Start: 2571794

End: 2572459

Strand: Reverse

Name: rocD1 [H]

Synonym: BCG_2343c

Alternate gene names: 121638208

Gene position: 2572459-2571794 (Counterclockwise)

Preceding gene: 121638209

Following gene: 121638207

Centisome position: 58.81

GC content: 64.86

Gene sequence:

>666_bases
ATGACAAATCTCGCGGATGCCACTCAGGCCACTATGGCACTGGTCGAAAGGCATGCAGCGCACAATTATTCGCCGCTGCC
TGTGGTGGCGGCCAGCGCTGAGGGTGCGTGGATCGCCGATATCGACGGCCTGCGCTACCTGGACTGGCTGGCTGCGTACT
CGGCGGTCAACCTTGGCCATCGCAACCCCGCGAGCACCGCCACGGCTCATGCCCAAGTCGACACCGTCACCCTGCTGAAT
CGGGCCTTGCATGCCGACCGACTCGGGCCGTTGGGCGCCGCGCTTGCCCAGCTGTGCGGCAAAGACGTGGTGTTGCCAAT
GAACTCTGATGCTGAAGCGGTGGAGAGCGGTCTTAGGGTCGCCCGCAAGTGGGGAGCCGACGTCAACGGCCTCCCCGCGG
GCCGGCACGATATCATTTTGGCAAACAACAACTTTCATGGCCACACCAGCAGTGTCGTCAGCTTCTCGTCGGACCCGGCT
GCGGGCAGCGGCGTCGAACCTTCTACCCCGGGACTCCGCTCGGTACCGTTTGGCGATGCTGCGGCACCGGCGCAGACAAT
CGACGACAACACCGTCGCTGACCTGCTCGAGCCGATTCCCGGCCAGGCGGGCATCATCGTCCCGGCCGACGACTACCTGC
CGGCTGCGTCGAGCACAACGTGCTGA

Upstream 100 bases:

>100_bases
CGCAGTTACGCGCAGCCGGCTTCGAGCCGGTCGGTGTCGATCTGTCCGAGCTGCTCAAGGGCGGCGGTTCCGTCAAGTGC
TGCACGCTGGAGATACACCC

Downstream 100 bases:

>100_bases
TGATCGCCGACGAAATCCAATCGGGGCTGGCCTGTACGGGTTACCCGTTCGCCTGCGACCACGGGGGTGTGCTGCCAGAC
ATTTACCTGCTCGGCAAGAC

Product: putative ornithine aminotransferase (N-terminus part) rocD1

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAAYSAVNLGHRNPASTATAHAQVDTVTLLN
RALHADRLGPLGAALAQLCGKDVVLPMNSDAEAVESGLRVARKWGADVNGLPAGRHDIILANNNFHGHTSSVVSFSSDPA
AGSGVEPSTPGLRSVPFGDAAAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC

Sequences:

>Translated_221_residues
MTNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAAYSAVNLGHRNPASTATAHAQVDTVTLLN
RALHADRLGPLGAALAQLCGKDVVLPMNSDAEAVESGLRVARKWGADVNGLPAGRHDIILANNNFHGHTSSVVSFSSDPA
AGSGVEPSTPGLRSVPFGDAAAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC
>Mature_220_residues
TNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAAYSAVNLGHRNPASTATAHAQVDTVTLLNR
ALHADRLGPLGAALAQLCGKDVVLPMNSDAEAVESGLRVARKWGADVNGLPAGRHDIILANNNFHGHTSSVVSFSSDPAA
GSGVEPSTPGLRSVPFGDAAAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=198, Percent_Identity=39.3939393939394, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI284507298, Length=108, Percent_Identity=39.8148148148148, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI145693181, Length=194, Percent_Identity=29.8969072164948, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1789759, Length=191, Percent_Identity=29.3193717277487, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1788044, Length=191, Percent_Identity=28.2722513089005, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1786349, Length=208, Percent_Identity=25.4807692307692, Blast_Score=60, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25144271, Length=211, Percent_Identity=37.4407582938389, Blast_Score=164, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71981843, Length=172, Percent_Identity=37.2093023255814, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6323470, Length=229, Percent_Identity=37.117903930131, Blast_Score=148, Evalue=7e-37,
Organism=Drosophila melanogaster, GI21357415, Length=198, Percent_Identity=42.4242424242424, Blast_Score=174, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 22714; Mature: 22583

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAAYSAVNLGH
CCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCC
RNPASTATAHAQVDTVTLLNRALHADRLGPLGAALAQLCGKDVVLPMNSDAEAVESGLRV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
ARKWGADVNGLPAGRHDIILANNNFHGHTSSVVSFSSDPAAGSGVEPSTPGLRSVPFGDA
HHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
AAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC
CCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TNLADATQATMALVERHAAHNYSPLPVVAASAEGAWIADIDGLRYLDWLAAYSAVNLGH
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHHHHCCC
RNPASTATAHAQVDTVTLLNRALHADRLGPLGAALAQLCGKDVVLPMNSDAEAVESGLRV
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHH
ARKWGADVNGLPAGRHDIILANNNFHGHTSSVVSFSSDPAAGSGVEPSTPGLRSVPFGDA
HHHHCCCCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCC
AAPAQTIDDNTVADLLEPIPGQAGIIVPADDYLPAASSTTC
CCCCCCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA