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The map label for this gene is rocE [H]

Identifier: 121638206

GI number: 121638206

Start: 2569818

End: 2571248

Strand: Reverse

Name: rocE [H]

Synonym: BCG_2341c

Alternate gene names: 121638206

Gene position: 2571248-2569818 (Counterclockwise)

Preceding gene: 121638207

Following gene: 121638205

Centisome position: 58.78

GC content: 64.43

Gene sequence:

>1431_bases
TTGCCGACAACGTCGATGAGCCTTCGAGAACTGATGCTGCGGCGCCGCCCGGTGAGCGGCGCCCCGGTCGCATCCGGGGC
ATCGGGGAACCTCAAGCGGAGTTTCGGCACCTTCCAGCTGACCATGTTCGGGGTTGGCGCGACGATAGGTACCGGCATCT
TTTTCGTGCTTGCCCAGGCAGTTCCAGAGGCCGGCCCGGGCGTGATTGTTTCGTTCATCATCGCCGGCATCGCCGCTGGG
CTCGCGGCTATCTGCTACGCGGAACTGGCTTCCGCCGTGCCGATTTCCGGGTCGGCGTACTCCTACGCGTACACGACGCT
GGGCGAGGCGGTCGCGATGGTGGTGGCGGCCTGCCTACTGCTGGAATACGGGGTAGCCACCGCAGCGGTCGCGGTCGGCT
GGAGTGGCTACGTGAACAAGCTGCTGAGTAATCTGTTCGGATTTCAGATGCCGCACGTATTGTCGGCGGCGCCGTGGGAC
ACCCATCCCGGTTGGGTGAACCTGCCCGCCGTCATCCTGATCGGGCTATGCGCGCTGCTGTTGATTCGAGGGGCCAGCGA
GTCGGCGAGGGTCAACGCGATCATGGTGCTGATCAAGCTCGGCGTGCTGGGCATGTTCATGATCATCGCGTTCAGCGCGT
ACAGCGCCGACCACCTCAAGGATTTCGTCCCATTCGGCGTCGCCGGCATCGGCTCCGCGGCGGGCACGATCTTCTTCTCA
TACATCGGCCTTGACGCGGTGTCGACCGCCGGCGACGAGGTGAAGGACCCGCAGAAGACCATGCCGCGTGCGCTGATCGC
AGCGCTGGTGGTCGTCACCGGTGTCTACGTGCTGGTCGCACTGGCCGCGCTGGGCACCCAACCGTGGCAGGACTTCGCAG
AGCAGGAAACCGCCGGGCTGGCCATCATCTTGGACAACGTCACGCATGGCGAATGGGCCAGCACGATTCTGGCCGCCGGT
GCGGTGGTCTCGATTTTCACCGTCACGCTGGTCACCATGTACGGCCAGACCCGGATCCTGTTCGCGATGGGGCGCGACGG
GCTGCTGCCGGCGCGGTTCGCGAAGGTGAATCCGCGCACCATGACGCCGGTGCACAACACGGTGATCGTCGCGATCTTCG
CATCGACGCTGGCCGCCTTCATACCGCTGGATAGCTTGGCGGACATGGTGTCCATCGGCACGCTCACCGCGTTCAGCGTG
GTGGCTGTGGGTGTGATCGTTCTACGGGTGCGCGAGCCCGACTTACCCCGAGGGTTCAAGGTACCCGGTTACCCTGTGAC
GCCTGTTCTTTCGGTGCTGGCCTGCGGGTATATCCTGGCCAGCTTGCACTGGTACACCTGGCTGGCGTTCAGCGGATGGG
TGGCGGTGGCAGTGATCTTTTACCTGATGTGGGGTCGGCACCACAGTGCGCTCAACGAGGAAGTGCCGTGA

Upstream 100 bases:

>100_bases
CGCCGCCCTGCGGTTCGCGCCGCCGTTAGTGATCACCGCGCAGGAGATCGACTGCGCGGTTCGCCGGTTCGCCGACGCGC
TATGGGAGGCGGGTTCATAA

Downstream 100 bases:

>100_bases
CCATCGTCGTCGGGTATTTGGCTGGCAAGGTCGGTCCGTCCGCATTACATCTAGCCGTCCGCGTCGCGCGGATGCACAAG
ACGTCGCTCACAGTGGCCAC

Product: putative cationic amino acid transport integral membrane protein rocE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 475

Protein sequence:

>476_residues
MPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQAVPEAGPGVIVSFIIAGIAAG
LAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLLEYGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWD
THPGWVNLPAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYSADHLKDFVPFGVAGIGSAAGTIFFS
YIGLDAVSTAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALGTQPWQDFAEQETAGLAIILDNVTHGEWASTILAAG
AVVSIFTVTLVTMYGQTRILFAMGRDGLLPARFAKVNPRTMTPVHNTVIVAIFASTLAAFIPLDSLADMVSIGTLTAFSV
VAVGVIVLRVREPDLPRGFKVPGYPVTPVLSVLACGYILASLHWYTWLAFSGWVAVAVIFYLMWGRHHSALNEEVP

Sequences:

>Translated_476_residues
MPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQAVPEAGPGVIVSFIIAGIAAG
LAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLLEYGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWD
THPGWVNLPAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYSADHLKDFVPFGVAGIGSAAGTIFFS
YIGLDAVSTAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALGTQPWQDFAEQETAGLAIILDNVTHGEWASTILAAG
AVVSIFTVTLVTMYGQTRILFAMGRDGLLPARFAKVNPRTMTPVHNTVIVAIFASTLAAFIPLDSLADMVSIGTLTAFSV
VAVGVIVLRVREPDLPRGFKVPGYPVTPVLSVLACGYILASLHWYTWLAFSGWVAVAVIFYLMWGRHHSALNEEVP
>Mature_475_residues
PTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQAVPEAGPGVIVSFIIAGIAAGL
AAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLLLEYGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWDT
HPGWVNLPAVILIGLCALLLIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYSADHLKDFVPFGVAGIGSAAGTIFFSY
IGLDAVSTAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALGTQPWQDFAEQETAGLAIILDNVTHGEWASTILAAGA
VVSIFTVTLVTMYGQTRILFAMGRDGLLPARFAKVNPRTMTPVHNTVIVAIFASTLAAFIPLDSLADMVSIGTLTAFSVV
AVGVIVLRVREPDLPRGFKVPGYPVTPVLSVLACGYILASLHWYTWLAFSGWVAVAVIFYLMWGRHHSALNEEVP

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=446, Percent_Identity=34.304932735426, Blast_Score=206, Evalue=5e-53,
Organism=Homo sapiens, GI258645169, Length=439, Percent_Identity=33.0296127562642, Blast_Score=196, Evalue=5e-50,
Organism=Homo sapiens, GI258614005, Length=439, Percent_Identity=32.1184510250569, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI258614003, Length=439, Percent_Identity=32.1184510250569, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI114326544, Length=442, Percent_Identity=31.9004524886878, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI114326550, Length=442, Percent_Identity=31.9004524886878, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI110347453, Length=413, Percent_Identity=32.4455205811138, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI181337167, Length=432, Percent_Identity=31.25, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI33286428, Length=430, Percent_Identity=26.046511627907, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI115648063, Length=446, Percent_Identity=23.3183856502242, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI115648022, Length=446, Percent_Identity=23.3183856502242, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI186910308, Length=423, Percent_Identity=23.8770685579196, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI186910306, Length=423, Percent_Identity=23.8770685579196, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI186910304, Length=423, Percent_Identity=23.8770685579196, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI71979932, Length=208, Percent_Identity=27.8846153846154, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI187423910, Length=434, Percent_Identity=22.1198156682028, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI7657591, Length=434, Percent_Identity=22.1198156682028, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI7657683, Length=375, Percent_Identity=22.1333333333333, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI33286430, Length=190, Percent_Identity=28.4210526315789, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI71999149, Length=418, Percent_Identity=23.6842105263158, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI87081869, Length=434, Percent_Identity=22.5806451612903, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786694, Length=395, Percent_Identity=26.3291139240506, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788480, Length=439, Percent_Identity=23.6902050113895, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786789, Length=437, Percent_Identity=23.7986270022883, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786302, Length=381, Percent_Identity=25.1968503937008, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87082023, Length=413, Percent_Identity=23.4866828087167, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081708, Length=440, Percent_Identity=25, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082250, Length=481, Percent_Identity=24.1164241164241, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786602, Length=477, Percent_Identity=22.6415094339623, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789017, Length=364, Percent_Identity=25, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790653, Length=352, Percent_Identity=21.3068181818182, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87081915, Length=432, Percent_Identity=21.9907407407407, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=453, Percent_Identity=32.8918322295806, Blast_Score=213, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17533459, Length=424, Percent_Identity=31.6037735849057, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17531343, Length=420, Percent_Identity=30.952380952381, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI32566699, Length=363, Percent_Identity=25.068870523416, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17540018, Length=429, Percent_Identity=24.4755244755245, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71982612, Length=412, Percent_Identity=22.3300970873786, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71982608, Length=412, Percent_Identity=22.3300970873786, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24668806, Length=433, Percent_Identity=34.4110854503464, Blast_Score=228, Evalue=6e-60,
Organism=Drosophila melanogaster, GI21356285, Length=433, Percent_Identity=34.4110854503464, Blast_Score=228, Evalue=6e-60,
Organism=Drosophila melanogaster, GI24668802, Length=433, Percent_Identity=34.4110854503464, Blast_Score=228, Evalue=6e-60,
Organism=Drosophila melanogaster, GI24667468, Length=391, Percent_Identity=34.2710997442455, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI221512776, Length=434, Percent_Identity=34.1013824884793, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24666159, Length=434, Percent_Identity=34.1013824884793, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI281366235, Length=424, Percent_Identity=31.1320754716981, Blast_Score=168, Evalue=9e-42,
Organism=Drosophila melanogaster, GI116007820, Length=424, Percent_Identity=31.1320754716981, Blast_Score=168, Evalue=9e-42,
Organism=Drosophila melanogaster, GI116007818, Length=424, Percent_Identity=31.1320754716981, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI85725152, Length=424, Percent_Identity=31.1320754716981, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI161077963, Length=390, Percent_Identity=31.2820512820513, Blast_Score=156, Evalue=3e-38,
Organism=Drosophila melanogaster, GI24641993, Length=419, Percent_Identity=23.3890214797136, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24641995, Length=419, Percent_Identity=23.3890214797136, Blast_Score=86, Evalue=8e-17,
Organism=Drosophila melanogaster, GI45550968, Length=416, Percent_Identity=26.2019230769231, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19921172, Length=416, Percent_Identity=26.2019230769231, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21357367, Length=422, Percent_Identity=21.8009478672986, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI221331183, Length=429, Percent_Identity=22.8438228438228, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17647653, Length=429, Percent_Identity=22.8438228438228, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24664379, Length=429, Percent_Identity=22.8438228438228, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24651635, Length=393, Percent_Identity=24.6819338422392, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24651633, Length=393, Percent_Identity=24.6819338422392, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49947; Mature: 49816

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQA
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEEEEECHHHHHHHHHHHHHHH
VPEAGPGVIVSFIIAGIAAGLAAICYAELASAVPISGSAYSYAYTTLGEAVAMVVAACLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LEYGVATAAVAVGWSGYVNKLLSNLFGFQMPHVLSAAPWDTHPGWVNLPAVILIGLCALL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
LIRGASESARVNAIMVLIKLGVLGMFMIIAFSAYSADHLKDFVPFGVAGIGSAAGTIFFS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHCCHHHHHHHHH
YIGLDAVSTAGDEVKDPQKTMPRALIAALVVVTGVYVLVALAALGTQPWQDFAEQETAGL
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCE
AIILDNVTHGEWASTILAAGAVVSIFTVTLVTMYGQTRILFAMGRDGLLPARFAKVNPRT
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHCCCCCC
MTPVHNTVIVAIFASTLAAFIPLDSLADMVSIGTLTAFSVVAVGVIVLRVREPDLPRGFK
CCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
VPGYPVTPVLSVLACGYILASLHWYTWLAFSGWVAVAVIFYLMWGRHHSALNEEVP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC
>Mature Secondary Structure 
PTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGVGATIGTGIFFVLAQA
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCCCEEEEEEECHHHHHHHHHHHHHHH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CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]