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The map label for this gene is galU [H]

Identifier: 121636920

GI number: 121636920

Start: 1139761

End: 1140681

Strand: Direct

Name: galU [H]

Synonym: BCG_1048

Alternate gene names: 121636920

Gene position: 1139761-1140681 (Clockwise)

Preceding gene: 121636915

Following gene: 121636921

Centisome position: 26.05

GC content: 66.23

Gene sequence:

>921_bases
ATGTCACGCCCAGAAGTACTAACGCCGTTCACGGCAATCGTCCCGGCAGCCGGCCTGGGTACGCGCTTTCTGCCGGCCAC
CAAGACGGTGCCCAAGGAGCTGCTGCCCGTCGTCGACACTCCCGGTATCGAGCTGGTGGCCGCCGAGGCGGCCGCGGCCG
GTGCCGAACGGCTGGTGATCGTCACCTCCGAGGGTAAGGACGGGGTGGTCGCGCATTTCGTGGAAGACCTGGTGCTGGAG
GGCACGCTCGAGGCCCGAGGCAAGATCGCCATGCTGGCCAAGGTGCGTCGCGCCCCGGCACTGATCAAGGTCGAATCCGT
GGTGCAGGCCGAGCCGCTGGGACTGGGACACGCCATCGGCTGTGTGGAGCCGACGCTGTCGCCCGACGAAGACGCTGTCG
CGGTGCTGCTGCCTGACGACCTGGTGCTGCCGACCGGCGTCCTGGAGACGATGTCGAAGGTGCGAGCCAGCAGGGGCGGC
ACCGTGCTGTGTGCTATCGAGGTGGCGCGCGAGGAGATCAGTGCCTACGGGGTTTTCGATGTCGAGCCGGTCCCCGATGG
TGACTACACCGACGATCCCAACGTGCTGAAGGTCAGGGGCATGGTCGAAAAGCCCAAGGCCGAAACGGCGCCGTCGAGGT
ATGCGGCGGCCGGCCGCTACGTTCTAGACCGTGCCATCTTCGATGCGTTACGCCGCATCGACCGGGGTGCAGGCGGTGAA
GTGCAGCTCACCGATGCGATCGCGCTGCTGATTGCCGAGGGCCATCCCGTCCATGTCGTCGTCCACCAAGGGTCCCGACA
CGACCTGGGAAATCCGGGCGGGTACCTCAAGGCTGCGGTTGACTTTGCATTGGATCGTGACGACTACGGCCCGGACTTGC
GGCGATGGTTGGTGGCGCGACTGGGTCTGACAGAGCAGTAG

Upstream 100 bases:

>100_bases
GTCCTCAACGATGACACAGCCCCGGCCGTCCCGCGCGAGCGCCGGGACAGCGCCAACGAAGAGGCGGGCAATCAGCACGC
TGCGGGTTATCGTGTGAACG

Downstream 100 bases:

>100_bases
CCTGGCGACGATACGGCACGGACGGTTCCGGGGTGGGGGATGCCCGGCCCCATGGCTCGACGGAAAGGCGGGCGCTGTGC
GTTCTGTGGAGGAGCAGCAG

Product: putative UTP--glucose-1-phosphate uridylyltransferase galU

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSRPEVLTPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVAAEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLE
GTLEARGKIAMLAKVRRAPALIKVESVVQAEPLGLGHAIGCVEPTLSPDEDAVAVLLPDDLVLPTGVLETMSKVRASRGG
TVLCAIEVAREEISAYGVFDVEPVPDGDYTDDPNVLKVRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDRGAGGE
VQLTDAIALLIAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWLVARLGLTEQ

Sequences:

>Translated_306_residues
MSRPEVLTPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVAAEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLE
GTLEARGKIAMLAKVRRAPALIKVESVVQAEPLGLGHAIGCVEPTLSPDEDAVAVLLPDDLVLPTGVLETMSKVRASRGG
TVLCAIEVAREEISAYGVFDVEPVPDGDYTDDPNVLKVRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDRGAGGE
VQLTDAIALLIAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWLVARLGLTEQ
>Mature_305_residues
SRPEVLTPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVAAEAAAAGAERLVIVTSEGKDGVVAHFVEDLVLEG
TLEARGKIAMLAKVRRAPALIKVESVVQAEPLGLGHAIGCVEPTLSPDEDAVAVLLPDDLVLPTGVLETMSKVRASRGGT
VLCAIEVAREEISAYGVFDVEPVPDGDYTDDPNVLKVRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDRGAGGEV
QLTDAIALLIAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWLVARLGLTEQ

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG) [H]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=301, Percent_Identity=38.5382059800665, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI1788355, Length=302, Percent_Identity=34.4370860927152, Blast_Score=148, Evalue=4e-37,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32407; Mature: 32275

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPEVLTPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVAAEAAAAGAERLVI
CCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEHHHHCCCCEEEE
VTSEGKDGVVAHFVEDLVLEGTLEARGKIAMLAKVRRAPALIKVESVVQAEPLGLGHAIG
EECCCCCCHHHHHHHHHHHHCCHHHCCCCHHHHHHHHCCCEEEEHHHHHCCCCCCCCCCC
CVEPTLSPDEDAVAVLLPDDLVLPTGVLETMSKVRASRGGTVLCAIEVAREEISAYGVFD
CCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHCCCEE
VEPVPDGDYTDDPNVLKVRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDRGAGGE
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VQLTDAIALLIAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWLVAR
EEEHHEEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHEECCCCCCHHHHHHHHHH
LGLTEQ
CCCCCC
>Mature Secondary Structure 
SRPEVLTPFTAIVPAAGLGTRFLPATKTVPKELLPVVDTPGIELVAAEAAAAGAERLVI
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCCCCEEEEEHHHHCCCCEEEE
VTSEGKDGVVAHFVEDLVLEGTLEARGKIAMLAKVRRAPALIKVESVVQAEPLGLGHAIG
EECCCCCCHHHHHHHHHHHHCCHHHCCCCHHHHHHHHCCCEEEEHHHHHCCCCCCCCCCC
CVEPTLSPDEDAVAVLLPDDLVLPTGVLETMSKVRASRGGTVLCAIEVAREEISAYGVFD
CCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHCCCEE
VEPVPDGDYTDDPNVLKVRGMVEKPKAETAPSRYAAAGRYVLDRAIFDALRRIDRGAGGE
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VQLTDAIALLIAEGHPVHVVVHQGSRHDLGNPGGYLKAAVDFALDRDDYGPDLRRWLVAR
EEEHHEEEEEEECCCEEEEEEECCCCCCCCCCCCHHHHHHHHEECCCCCCHHHHHHHHHH
LGLTEQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]