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The map label for this gene is fadE12

Identifier: 121636898

GI number: 121636898

Start: 1113060

End: 1114226

Strand: Reverse

Name: fadE12

Synonym: BCG_1026c

Alternate gene names: 121636898

Gene position: 1114226-1113060 (Counterclockwise)

Preceding gene: 121636899

Following gene: 121636897

Centisome position: 25.47

GC content: 64.35

Gene sequence:

>1167_bases
GTGACAGACACCAGCTTTATCGAAAGCGAGGAACGTCAGGCGCTGCGCAAGGCGGTGGCCTCTTGGGTGGCCAACTATGG
CCACGAGTACTACCTGGACAAGGCGCGCAAACACGAACACACCAGCGAGTTATGGGCCGAGGCAGGCAAACTCGGTTTTT
TGGGGGTGAATCTGCCCGAAGAGTACGGCGGCGGCGGCGCAGGCATGTACGAACTGTCGCTGGTGATGGAGGAGATGGCC
GCCGCCGGCTCGGCGCTGCTGCTGATGGTGGTGTCACCGGCCATCAACGGAACCATCATCGCCAAGTTCGGCACCGACGA
TCAGAAGAAGCGCTGGTTGCCGGGCATCGCCGACGGCTCGTTGACCATGGCGTTCGCCATCACCGAGCCCGACGCCGGCT
CCAACTCACACAAGATCACCACCACCGCGCGTCGCGACGGCAGCGACTGGATCATCAAGGGCCAGAAAGTCTTTATTTCT
GGCATCGACCAGGCGCAGGCGGTGCTGGTCGTGGGCCGCAGCGAGGAAGCCAAAACCGGCAAGCTACGCCCCGCGTTGTT
CGTGGTGCCCACCGACGCTCCCGGGTTCAGCTACACCCCGATCGAGATGGAGCTGGTCAGCCCCGAACGCCAGTTCCAGG
TTTTCCTCGACGACGTCCGGCTACCCGCCGATGCGCTGGTTGGAGCCGAAGACGCGGCGATCGCACATCTTTTCGCGGGC
CTGAACCCCGAGCGCATCATGGGTGCGGCTAGCGCGGTGGGCATGGGCCGGTTCGCACTCGGCAGGGCCGTCGACTACGT
CAAAACCCGCAAGGTGTGGTCCACCCCGATCGGCGCGCACCAGGGCCTGGCACATCCGTTGGCGCAGTGCCACATTGAGG
TCGAACTCGCCAAGCTGATGACCCAGAAAGCCGCCACACTCTACGACCATGGTGACGACTTCGGTGCGGCCGAGGCGGCC
AACATGGCCAAATACGCTGCGGCCGAGGCATCCAGCCGCGCGGTCGATCAGGCCGTACAGTCGATGGGCGGCAACGGCCT
CACCAAGGAATATGGCGTGGCAGCGATGATGACCTCGGCCCGCTTGGCGCGGATCGCCCCGATCAGCCGCGAGATGGTGC
TGAACTTCGTTGCGCAGACATCGCTGGGTCTGCCCCGGTCCTACTGA

Upstream 100 bases:

>100_bases
TCACCCACGTCAGCGTCAACACGGGTCAACAGGTCGAAGTAGGCGCCATTCTCGCACGAGTAGAAGCACCTCAAAATGGC
CCAGCAGAAGGAGATTCACC

Downstream 100 bases:

>100_bases
TGGACAGCCCCGTCGACTACGCTGGCCCGGCCGCCTGCGGCGGCCCCTTCGCCAGGCTGACACTGAACTCTCCGCACAAC
CGCAACGCGCTGTCGAGCAC

Product: putative acyl-CoA dehydrogenase fadE12

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSELWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMA
AAGSALLLMVVSPAINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTARRDGSDWIIKGQKVFIS
GIDQAQAVLVVGRSEEAKTGKLRPALFVVPTDAPGFSYTPIEMELVSPERQFQVFLDDVRLPADALVGAEDAAIAHLFAG
LNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQCHIEVELAKLMTQKAATLYDHGDDFGAAEAA
NMAKYAAAEASSRAVDQAVQSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY

Sequences:

>Translated_388_residues
MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSELWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMA
AAGSALLLMVVSPAINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTARRDGSDWIIKGQKVFIS
GIDQAQAVLVVGRSEEAKTGKLRPALFVVPTDAPGFSYTPIEMELVSPERQFQVFLDDVRLPADALVGAEDAAIAHLFAG
LNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQCHIEVELAKLMTQKAATLYDHGDDFGAAEAA
NMAKYAAAEASSRAVDQAVQSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY
>Mature_387_residues
TDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSELWAEAGKLGFLGVNLPEEYGGGGAGMYELSLVMEEMAA
AGSALLLMVVSPAINGTIIAKFGTDDQKKRWLPGIADGSLTMAFAITEPDAGSNSHKITTTARRDGSDWIIKGQKVFISG
IDQAQAVLVVGRSEEAKTGKLRPALFVVPTDAPGFSYTPIEMELVSPERQFQVFLDDVRLPADALVGAEDAAIAHLFAGL
NPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQCHIEVELAKLMTQKAATLYDHGDDFGAAEAAN
MAKYAAAEASSRAVDQAVQSMGGNGLTKEYGVAAMMTSARLARIAPISREMVLNFVAQTSLGLPRSY

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family

Homologues:

Organism=Homo sapiens, GI4501857, Length=383, Percent_Identity=30.0261096605744, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI4557233, Length=319, Percent_Identity=31.3479623824451, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4557231, Length=332, Percent_Identity=29.5180722891566, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI187960098, Length=332, Percent_Identity=29.5180722891566, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI226958412, Length=371, Percent_Identity=26.6846361185984, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI226958414, Length=367, Percent_Identity=27.2479564032698, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI4501859, Length=331, Percent_Identity=29.3051359516616, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI38505218, Length=302, Percent_Identity=28.476821192053, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI7656849, Length=384, Percent_Identity=25, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI211971008, Length=316, Percent_Identity=28.1645569620253, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI48976061, Length=316, Percent_Identity=28.1645569620253, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI76496475, Length=398, Percent_Identity=26.8844221105528, Blast_Score=105, Evalue=9e-23,
Organism=Homo sapiens, GI4557235, Length=398, Percent_Identity=26.8844221105528, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI21361497, Length=340, Percent_Identity=25.5882352941176, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4503943, Length=316, Percent_Identity=26.2658227848101, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI7669494, Length=316, Percent_Identity=26.2658227848101, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI87081958, Length=371, Percent_Identity=26.6846361185984, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786223, Length=369, Percent_Identity=24.9322493224932, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87081702, Length=334, Percent_Identity=24.8502994011976, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17534899, Length=368, Percent_Identity=29.8913043478261, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17506239, Length=330, Percent_Identity=29.0909090909091, Blast_Score=152, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17570075, Length=364, Percent_Identity=32.4175824175824, Blast_Score=152, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17508101, Length=330, Percent_Identity=28.4848484848485, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17569725, Length=376, Percent_Identity=28.4574468085106, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI71990804, Length=306, Percent_Identity=30.0653594771242, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17538396, Length=378, Percent_Identity=24.8677248677249, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17551932, Length=336, Percent_Identity=27.3809523809524, Blast_Score=128, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17505929, Length=333, Percent_Identity=28.2282282282282, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17533517, Length=351, Percent_Identity=24.7863247863248, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI32563615, Length=222, Percent_Identity=28.8288288288288, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=24.7887323943662, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17562446, Length=324, Percent_Identity=26.2345679012346, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI71982178, Length=269, Percent_Identity=26.0223048327138, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=328, Percent_Identity=24.390243902439, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=245, Percent_Identity=26.530612244898, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24666513, Length=331, Percent_Identity=29.607250755287, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI21356377, Length=361, Percent_Identity=29.0858725761773, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24660351, Length=371, Percent_Identity=28.3018867924528, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21355753, Length=384, Percent_Identity=27.8645833333333, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646207, Length=378, Percent_Identity=28.8359788359788, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281363737, Length=350, Percent_Identity=24.5714285714286, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI19920834, Length=354, Percent_Identity=26.5536723163842, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDC_MYCBO (Q7U0Y2)

Other databases:

- EMBL:   BX248337
- RefSeq:   NP_854654.1
- ProteinModelPortal:   Q7U0Y2
- SMR:   Q7U0Y2
- EnsemblBacteria:   EBMYCT00000016499
- GeneID:   1093082
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb0997c
- GeneTree:   EBGT00050000015287
- HOGENOM:   HBG699365
- OMA:   MMQKAAT
- ProtClustDB:   CLSK871880
- BioCyc:   MBOV233413:MB0997C-MONOMER
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- Gene3D:   G3DSA:2.40.110.10
- Gene3D:   G3DSA:1.10.540.10
- Gene3D:   G3DSA:1.20.140.10

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; SSF56645 AcylCoA_dehyd_NM; SSF47203 AcylCoADH_C_like

EC number: NA

Molecular weight: Translated: 41525; Mature: 41394

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00072 ACYL_COA_DH_1; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSELWAEAGKLGFLGVNLPE
CCCCHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCH
EYGGGGAGMYELSLVMEEMAAAGSALLLMVVSPAINGTIIAKFGTDDQKKRWLPGIADGS
HHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCHHHHCCCCCCCCC
LTMAFAITEPDAGSNSHKITTTARRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKTG
EEEEEEEECCCCCCCCCEEEEEECCCCCCEEEECCEEEEECCCCCEEEEEEECCCCCCCC
KLRPALFVVPTDAPGFSYTPIEMELVSPERQFQVFLDDVRLPADALVGAEDAAIAHLFAG
CCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHC
LNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQCHIEVELAKLM
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAVQSMGGNGLTKEYGVAAMMTSA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
RLARIAPISREMVLNFVAQTSLGLPRSY
HHHHHCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TDTSFIESEERQALRKAVASWVANYGHEYYLDKARKHEHTSELWAEAGKLGFLGVNLPE
CCCHHHCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCH
EYGGGGAGMYELSLVMEEMAAAGSALLLMVVSPAINGTIIAKFGTDDQKKRWLPGIADGS
HHCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCHHHHCCCCCCCCC
LTMAFAITEPDAGSNSHKITTTARRDGSDWIIKGQKVFISGIDQAQAVLVVGRSEEAKTG
EEEEEEEECCCCCCCCCEEEEEECCCCCCEEEECCEEEEECCCCCEEEEEEECCCCCCCC
KLRPALFVVPTDAPGFSYTPIEMELVSPERQFQVFLDDVRLPADALVGAEDAAIAHLFAG
CCCCEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCHHHHCCCCHHHHHHHHHC
LNPERIMGAASAVGMGRFALGRAVDYVKTRKVWSTPIGAHQGLAHPLAQCHIEVELAKLM
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
TQKAATLYDHGDDFGAAEAANMAKYAAAEASSRAVDQAVQSMGGNGLTKEYGVAAMMTSA
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
RLARIAPISREMVLNFVAQTSLGLPRSY
HHHHHCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972