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The map label for this gene is 121636836

Identifier: 121636836

GI number: 121636836

Start: 1047692

End: 1049200

Strand: Reverse

Name: 121636836

Synonym: BCG_0965c

Alternate gene names: NA

Gene position: 1049200-1047692 (Counterclockwise)

Preceding gene: 121636837

Following gene: 121636827

Centisome position: 23.98

GC content: 60.9

Gene sequence:

>1509_bases
ATGGACATCACGATTGTCGGCAAGTACTTGTCGACCCTTCCCGAAGACGACGACCACCCCTATCGCACCGGTCCGTGGCG
ACCACAGACCACCGAATGGGATGCCGACGACCTGACCACCGTGACAGGCGAAGTCCCCGCCGACCTGGACGGCATCTACC
TGCGCAACACCGAGAACCCGCTACACCCGGCATTCGCGACCTACCACCCCTTCGATGGCGACGGCATGATCCATGTCGTC
GGCTTCCGTGATGGAAAAGCCTTCTACCGCAACCGATTTATTCGCACCGATGGATTCTTGGCCGAGAACGAGGCCGGCGG
GCCGCTGTGGCCGGGTCTGGCAGAACCGGTGCAACTGGCCAAGCGGGAACACGGCTGGGGCGCTCGTGGCCTCATGAAGG
ACGCGTCGAGCACCGACGTCATCGTCCACCGAGGTATCGCGCTGACTAGCTTCTACCAGTGCGGCGATCTGTATCGGATC
GACCCGTACTCGGCCAATACGCTCGGCAAGGAGAGCTGGCACGGAAGGTTTCCGTTCGACTGGGGCGTGTCGGCACATCC
GAAGGTAGACAACAAGACCGGCGAACTGTTGTTCTTCAACTACAGCAAGCAAGAGCCGTATATGCGCTACGGCGTTGTCG
ACCAGAACAATGAGCTTGTGCACTATGTCGATGTTCCGCTGCCCGGGCCGCGGCTACCGCATGACATGGCGTTCACCGAA
AATTACGTAATCCTCAACGATTTTCCACTGTTCTGGGATCCCAGGCTGCTCGAGCGCGACGTGCACCTACCACGCTTCTA
TCCGGAGATTCCATCTCGGTTTGCGGTTGTTGCTCGCCGAGGCAACGACATTCGCTGGTTCGAAGCCGATCCAACGTTCG
TGTTGCACTTCACCAACGCCTACGAGCAGGGCGACGAGATCGTGCTCGACGGCTTCTACGAAGGCGATCCGCAGCCACTT
GACACCGGAGGAACGAAGTGGGAGAAGCTGTTTCGGTTCCTGGCTCTGGATCGGCTGCAGTCCCGGCTACATCGGTGGCG
GCTCAATATGGTGACCGGGGCAGTCCACGAGGAGCAACTGTCCGAGTCCATCACCGAGTTCGGAACCATCAACGCCGATT
ACGCGGCCAGCAGCTACCGTTACACCTATGCCGCTACCGGCAAACCGAGTTGGTTCCTGTTCGACGGACTGGTTAAGCAC
GATCTGCTCACCGGCAACCACGAGTGTTACTCGTTCGGTGACGGCGTCTACGGAAGTGAGACCGCGATGGCTCCACGGGT
GGGCAGCAGCGCCGAGGACGACGGCTATCTGGTCACCCTCACCACCGACATGAACGACGACGCATCGTATTGCCTGGTTT
TCGACGCGGCGCGCCCCGGCGATGGCCCGATATGCAAGCTTGCACTGCCGGAACGTATTTCCAGCGGCACGCATTCGGCG
TGGGTGCCGGGCGCCGAGTTGCGTCGCTGGGATCACGCAGAGTCGCCGGCGGCTGCCGTTGGGCTATGA

Upstream 100 bases:

>100_bases
TATCAGGTCGAGAACGCCGAAGCGTTCGGCACGCTGAATTTCGGTGGCAGCACGGCCACCACGGTCAGTTTCGTTGTCAG
CACCACACGAGGATCGTGAA

Downstream 100 bases:

>100_bases
ATTGCACCGAGCCGGAAAATCCGCAGCAAAACTGCGAGTAGCGGCCTGCAGAAGTGCAGCCTCGGCGAAACGGAGTAGCG
GTGGACAACGAAAAGCGCCG

Product: putative dioxygenase

Products: NA

Alternate protein names: ACO; 8'-apo-beta-carotenal 15,15'-oxygenase; Diox1 [H]

Number of amino acids: Translated: 502; Mature: 502

Protein sequence:

>502_residues
MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIHVV
GFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRI
DPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE
NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNAYEQGDEIVLDGFYEGDPQPL
DTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKH
DLLTGNHECYSFGDGVYGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA
WVPGAELRRWDHAESPAAAVGL

Sequences:

>Translated_502_residues
MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIHVV
GFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRI
DPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE
NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNAYEQGDEIVLDGFYEGDPQPL
DTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKH
DLLTGNHECYSFGDGVYGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA
WVPGAELRRWDHAESPAAAVGL
>Mature_502_residues
MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENPLHPAFATYHPFDGDGMIHVV
GFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLAKREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRI
DPYSANTLGKESWHGRFPFDWGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE
NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNAYEQGDEIVLDGFYEGDPQPL
DTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQLSESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKH
DLLTGNHECYSFGDGVYGSETAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA
WVPGAELRRWDHAESPAAAVGL

Specific function: Cleaves a number of carotenals and carotenols in the all-trans configuration at the 15-15' double bond producing retinal or retinol, respectively. Also shows activity toward lycopenals and the corresponding alcohols. Does not cleave beta- carotene or lyco

COG id: COG3670

COG function: function code Q; Lignostilbene-alpha,beta-dioxygenase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004294 [H]

Pfam domain/function: PF03055 RPE65 [H]

EC number: =1.14.99.41 [H]

Molecular weight: Translated: 56640; Mature: 56640

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP
CCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCC
LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA
CCCCEEECCCCCCCCEEEEEEECCCHHHHHCCEEECCCEEECCCCCCCCCCCHHHHHHHH
KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD
HHCCCCCCCHHHCCCCCCCEEEECCCCEEHHHHCCCEEEECCCCCCCCCCCCCCCCCCCC
WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCEECC
NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNA
CEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCC
YEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQL
CCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSE
HHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEHHHHHHHHCCCCCCEEECCCCCCCCC
TAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA
CCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCEEEEECHHHHCCCCCCC
WVPGAELRRWDHAESPAAAVGL
CCCCHHHHHCCCCCCCCHHCCC
>Mature Secondary Structure
MDITIVGKYLSTLPEDDDHPYRTGPWRPQTTEWDADDLTTVTGEVPADLDGIYLRNTENP
CCEEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCC
LHPAFATYHPFDGDGMIHVVGFRDGKAFYRNRFIRTDGFLAENEAGGPLWPGLAEPVQLA
CCCCEEECCCCCCCCEEEEEEECCCHHHHHCCEEECCCEEECCCCCCCCCCCHHHHHHHH
KREHGWGARGLMKDASSTDVIVHRGIALTSFYQCGDLYRIDPYSANTLGKESWHGRFPFD
HHCCCCCCCHHHCCCCCCCEEEECCCCEEHHHHCCCEEEECCCCCCCCCCCCCCCCCCCC
WGVSAHPKVDNKTGELLFFNYSKQEPYMRYGVVDQNNELVHYVDVPLPGPRLPHDMAFTE
CCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCEECC
NYVILNDFPLFWDPRLLERDVHLPRFYPEIPSRFAVVARRGNDIRWFEADPTFVLHFTNA
CEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEEECCC
YEQGDEIVLDGFYEGDPQPLDTGGTKWEKLFRFLALDRLQSRLHRWRLNMVTGAVHEEQL
CCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SESITEFGTINADYAASSYRYTYAATGKPSWFLFDGLVKHDLLTGNHECYSFGDGVYGSE
HHHHHHHCCCCCCCCCCCEEEEEEECCCCCEEEEHHHHHHHHCCCCCCEEECCCCCCCCC
TAMAPRVGSSAEDDGYLVTLTTDMNDDASYCLVFDAARPGDGPICKLALPERISSGTHSA
CCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCCCCCCEEEEECHHHHCCCCCCC
WVPGAELRRWDHAESPAAAVGL
CCCCHHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]