| Definition | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome. |
|---|---|
| Accession | NC_008769 |
| Length | 4,374,522 |
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The map label for this gene is ligD [H]
Identifier: 121636774
GI number: 121636774
Start: 978147
End: 978974
Strand: Reverse
Name: ligD [H]
Synonym: BCG_0903c
Alternate gene names: 121636774
Gene position: 978974-978147 (Counterclockwise)
Preceding gene: 121636776
Following gene: 121636769
Centisome position: 22.38
GC content: 66.18
Gene sequence:
>828_bases GTGGACGGGTTTCCCGGGCGCGGTGCGGTCATCACTGGCGGTGCCAGTGGCATCGGGTTGGCTACCGGCACCGAGTTCGC CCGCCGCGGAGCCAGAGTCGTGCTAGGGGACGTTGACAAGCCGGGACTTCGGCAGGCGGTGAACCACCTGCGTGCCGAGG GGTTCGATGTGCACGGCGTGATGTGCGACGTCCGGCATCGAGAAGAGGTCACTCACCTCGCGGACGAGGCTTTCCGCCTG CTCGGCCACGTCGATGTCGTATTCAGCAACGCCGGCATCGTTGTCGGCGGTCCGATCGTGGAGATGACGCACGACGACTG GCGTTGGGTGATCGACGTCGACCTGTGGGGCTCGATCCATACGGTCGAAGCGTTCCTGCCGAGGTTGCTTGAGCAGGGCA CGGGCGGGCATGTGGTGTTCACCGCGTCCTTTGCCGGGCTGGTGCCCAATGCCGGACTCGGCGCATACGGCGTTGCCAAG TACGGGGTTGTCGGTCTGGCGGAGACGCTGGCCCGCGAGGTCACCGCCGACGGCATTGGGGTGTCGGTGCTCTGCCCGAT GGTCGTCGAAACCAATCTGGTTGCCAACTCTGAACGAATCCGAGGCGCGGCTTGCGCGCAGTCCTCAACGACGGGATCGC CCGGTCCACTCCCCCTGCAGGACGACAACCTGGGCGTCGACGATATCGCCCAGCTAACAGCCGATGCGATTCTGGCCAAC CGCCTCTACGTCCTTCCGCATGCGGCCTCGCGCGCTTCGATCCGCCGCAGGTTCGAGCGCATTGACCGCACCTTCGACGA ACAGGCCGCCGAGGGGTGGCGGCATTAG
Upstream 100 bases:
>100_bases TTGTGAACACCGCGACGCAACATGCCGCTGTGGCGTCGCCAGAATCACGCTCGCCCGGCGCAGTCGACGCGGGTGACTGC CTGAAATAGGGTTGCGTGCT
Downstream 100 bases:
>100_bases CTTTGATTTTCCTTAAGGCTCGATGTCAGATGGTGCGTCATGTCGGCATGTCGTCGCGCATCCCATCTCTTGTCAGCATC GGGTATGAGGGAAGAACCGT
Product: short chain dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 275; Mature: 275
Protein sequence:
>275_residues MDGFPGRGAVITGGASGIGLATGTEFARRGARVVLGDVDKPGLRQAVNHLRAEGFDVHGVMCDVRHREEVTHLADEAFRL LGHVDVVFSNAGIVVGGPIVEMTHDDWRWVIDVDLWGSIHTVEAFLPRLLEQGTGGHVVFTASFAGLVPNAGLGAYGVAK YGVVGLAETLAREVTADGIGVSVLCPMVVETNLVANSERIRGAACAQSSTTGSPGPLPLQDDNLGVDDIAQLTADAILAN RLYVLPHAASRASIRRRFERIDRTFDEQAAEGWRH
Sequences:
>Translated_275_residues MDGFPGRGAVITGGASGIGLATGTEFARRGARVVLGDVDKPGLRQAVNHLRAEGFDVHGVMCDVRHREEVTHLADEAFRL LGHVDVVFSNAGIVVGGPIVEMTHDDWRWVIDVDLWGSIHTVEAFLPRLLEQGTGGHVVFTASFAGLVPNAGLGAYGVAK YGVVGLAETLAREVTADGIGVSVLCPMVVETNLVANSERIRGAACAQSSTTGSPGPLPLQDDNLGVDDIAQLTADAILAN RLYVLPHAASRASIRRRFERIDRTFDEQAAEGWRH >Mature_275_residues MDGFPGRGAVITGGASGIGLATGTEFARRGARVVLGDVDKPGLRQAVNHLRAEGFDVHGVMCDVRHREEVTHLADEAFRL LGHVDVVFSNAGIVVGGPIVEMTHDDWRWVIDVDLWGSIHTVEAFLPRLLEQGTGGHVVFTASFAGLVPNAGLGAYGVAK YGVVGLAETLAREVTADGIGVSVLCPMVVETNLVANSERIRGAACAQSSTTGSPGPLPLQDDNLGVDDIAQLTADAILAN RLYVLPHAASRASIRRRFERIDRTFDEQAAEGWRH
Specific function: Catalyzes the C alpha dehydrogenation of arylglycerol- beta-aryl ether (C alpha alcohol type) (compound IV) [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40807363, Length=243, Percent_Identity=30.0411522633745, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI32483357, Length=193, Percent_Identity=31.6062176165803, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI142976729, Length=194, Percent_Identity=31.4432989690722, Blast_Score=99, Evalue=6e-21, Organism=Homo sapiens, GI210032110, Length=194, Percent_Identity=30.9278350515464, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI25282469, Length=224, Percent_Identity=32.1428571428571, Blast_Score=96, Evalue=5e-20, Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=30.9782608695652, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI5031737, Length=191, Percent_Identity=29.8429319371728, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=30.3191489361702, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI310128830, Length=251, Percent_Identity=26.6932270916335, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI310115468, Length=251, Percent_Identity=26.6932270916335, Blast_Score=88, Evalue=7e-18, Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=31.1827956989247, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI4503817, Length=204, Percent_Identity=28.4313725490196, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI20149619, Length=239, Percent_Identity=26.3598326359833, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI4504505, Length=192, Percent_Identity=31.7708333333333, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI126723750, Length=196, Percent_Identity=27.5510204081633, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI66933014, Length=202, Percent_Identity=25.7425742574257, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI15277342, Length=193, Percent_Identity=30.0518134715026, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI4758504, Length=199, Percent_Identity=30.6532663316583, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI19923817, Length=193, Percent_Identity=26.4248704663212, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI31543615, Length=147, Percent_Identity=31.2925170068027, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=26.3681592039801, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI83715985, Length=182, Percent_Identity=30.7692307692308, Blast_Score=67, Evalue=1e-11, Organism=Escherichia coli, GI87082100, Length=236, Percent_Identity=29.2372881355932, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1787335, Length=205, Percent_Identity=29.7560975609756, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1786701, Length=191, Percent_Identity=30.8900523560209, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1789208, Length=198, Percent_Identity=24.7474747474747, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI1787905, Length=188, Percent_Identity=28.1914893617021, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1788459, Length=186, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1786812, Length=210, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1790717, Length=188, Percent_Identity=25, Blast_Score=68, Evalue=8e-13, Organism=Escherichia coli, GI2367365, Length=194, Percent_Identity=30.4123711340206, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI1789378, Length=193, Percent_Identity=24.8704663212435, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1787820, Length=246, Percent_Identity=23.9837398373984, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI17564282, Length=248, Percent_Identity=29.8387096774194, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI193203117, Length=241, Percent_Identity=30.7053941908714, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI193203115, Length=241, Percent_Identity=30.7053941908714, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17567345, Length=197, Percent_Identity=32.48730964467, Blast_Score=104, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17508895, Length=226, Percent_Identity=25.6637168141593, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17560676, Length=188, Percent_Identity=29.7872340425532, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17561402, Length=192, Percent_Identity=28.125, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI25147288, Length=187, Percent_Identity=31.0160427807487, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17568967, Length=192, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI71994600, Length=217, Percent_Identity=27.6497695852535, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17555706, Length=187, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71994604, Length=216, Percent_Identity=27.3148148148148, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17507613, Length=208, Percent_Identity=29.8076923076923, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI32563809, Length=208, Percent_Identity=29.8076923076923, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17544670, Length=207, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562910, Length=202, Percent_Identity=25.2475247524752, Blast_Score=65, Evalue=4e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=32.6424870466321, Blast_Score=85, Evalue=1e-17, Organism=Saccharomyces cerevisiae, GI6320089, Length=193, Percent_Identity=25.9067357512953, Blast_Score=74, Evalue=2e-14, Organism=Drosophila melanogaster, GI21355319, Length=195, Percent_Identity=32.3076923076923, Blast_Score=103, Evalue=2e-22, Organism=Drosophila melanogaster, GI24640492, Length=200, Percent_Identity=28.5, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI281364892, Length=198, Percent_Identity=32.3232323232323, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI24581726, Length=194, Percent_Identity=29.8969072164948, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI18859837, Length=197, Percent_Identity=34.5177664974619, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI21355631, Length=170, Percent_Identity=31.1764705882353, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI24644339, Length=191, Percent_Identity=29.3193717277487, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI28571387, Length=210, Percent_Identity=29.5238095238095, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI21358495, Length=221, Percent_Identity=25.3393665158371, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI23397609, Length=184, Percent_Identity=30.9782608695652, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24639444, Length=192, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI221510726, Length=196, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI24663911, Length=218, Percent_Identity=29.3577981651376, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI21356301, Length=192, Percent_Identity=27.6041666666667, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24665243, Length=204, Percent_Identity=30.8823529411765, Blast_Score=72, Evalue=6e-13, Organism=Drosophila melanogaster, GI221331218, Length=204, Percent_Identity=30.8823529411765, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24641388, Length=206, Percent_Identity=32.0388349514563, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24665247, Length=205, Percent_Identity=30.7317073170732, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI17737361, Length=207, Percent_Identity=27.0531400966184, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI221331216, Length=205, Percent_Identity=30.7317073170732, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=25.6410256410256, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24641232, Length=213, Percent_Identity=28.169014084507, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 29219; Mature: 29219
Theoretical pI: Translated: 5.53; Mature: 5.53
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 1.5 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDGFPGRGAVITGGASGIGLATGTEFARRGARVVLGDVDKPGLRQAVNHLRAEGFDVHGV CCCCCCCCEEEECCCCCCCCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEE MCDVRHREEVTHLADEAFRLLGHVDVVFSNAGIVVGGPIVEMTHDDWRWVIDVDLWGSIH EECCHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCCEEEEECCCCEEEEEEECCCCHH TVEAFLPRLLEQGTGGHVVFTASFAGLVPNAGLGAYGVAKYGVVGLAETLAREVTADGIG HHHHHHHHHHHCCCCCEEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC VSVLCPMVVETNLVANSERIRGAACAQSSTTGSPGPLPLQDDNLGVDDIAQLTADAILAN HHHHHHHHHHHHHHCCCHHHCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH RLYVLPHAASRASIRRRFERIDRTFDEQAAEGWRH CEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCC >Mature Secondary Structure MDGFPGRGAVITGGASGIGLATGTEFARRGARVVLGDVDKPGLRQAVNHLRAEGFDVHGV CCCCCCCCEEEECCCCCCCCCCCHHHHHCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEE MCDVRHREEVTHLADEAFRLLGHVDVVFSNAGIVVGGPIVEMTHDDWRWVIDVDLWGSIH EECCHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCCEEEEECCCCEEEEEEECCCCHH TVEAFLPRLLEQGTGGHVVFTASFAGLVPNAGLGAYGVAKYGVVGLAETLAREVTADGIG HHHHHHHHHHHCCCCCEEEEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC VSVLCPMVVETNLVANSERIRGAACAQSSTTGSPGPLPLQDDNLGVDDIAQLTADAILAN HHHHHHHHHHHHHHCCCHHHCHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH RLYVLPHAASRASIRRRFERIDRTFDEQAAEGWRH CEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 1744051; 8495726; 7764263 [H]