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The map label for this gene is czrA [H]

Identifier: 121636751

GI number: 121636751

Start: 951162

End: 951554

Strand: Reverse

Name: czrA [H]

Synonym: BCG_0880c

Alternate gene names: 121636751

Gene position: 951554-951162 (Counterclockwise)

Preceding gene: 121636752

Following gene: 121636749

Centisome position: 21.75

GC content: 64.38

Gene sequence:

>393_bases
ATGTACGCAGATAGTGGACCTGACCCGTTGCCTGACGATCAGGTCTGCTTGGTGGTCGAGGTGTTCCGAATGCTCGCCGA
CGCGACCCGCGTGCAGGTGCTGTGGTCGCTGGCAGACCGCGAAATGTCGGTCAATGAACTCGCCGAGCAGGTGGGCAAGC
CCGCGCCGTCGGTCTCCCAGCACCTGGCAAAGCTACGAATGGCGCGGCTGGTGCGCACCCGCCGCGATGGAACCACGATC
TTTTACCGTCTGGAGAACGAGCACGTGCGCCAGCTCGTCATCGACGCCGTTTTCAACGCCGAGCACGCCGGTCCCGGGAT
TCCCCGCCACCACCGTGCTGCCGGCGGACTGCAGTCGGTCGCTAAGGCATCGGCTACCAAGGATGTCGGGTAA

Upstream 100 bases:

>100_bases
CAACGGCGGTGAGCGCAGCGCGATCGCCGCTCCGACGGGCTGAGCGGGCGCCGACCCGCGACCTTGACAGCCCACCACGC
CCGCGTTCTATTGTTTGCGT

Downstream 100 bases:

>100_bases
GCCAATTAACGGTGAGCACAACCACGCCCCGGTTGCGCCGCAGGTCCGGGGTCAGACCTTAGGGCAGTAGTGCGTCGGGT
TGTCACGCTCGTCGGGCGGC

Product: putative transcriptional regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 130; Mature: 130

Protein sequence:

>130_residues
MYADSGPDPLPDDQVCLVVEVFRMLADATRVQVLWSLADREMSVNELAEQVGKPAPSVSQHLAKLRMARLVRTRRDGTTI
FYRLENEHVRQLVIDAVFNAEHAGPGIPRHHRAAGGLQSVAKASATKDVG

Sequences:

>Translated_130_residues
MYADSGPDPLPDDQVCLVVEVFRMLADATRVQVLWSLADREMSVNELAEQVGKPAPSVSQHLAKLRMARLVRTRRDGTTI
FYRLENEHVRQLVIDAVFNAEHAGPGIPRHHRAAGGLQSVAKASATKDVG
>Mature_130_residues
MYADSGPDPLPDDQVCLVVEVFRMLADATRVQVLWSLADREMSVNELAEQVGKPAPSVSQHLAKLRMARLVRTRRDGTTI
FYRLENEHVRQLVIDAVFNAEHAGPGIPRHHRAAGGLQSVAKASATKDVG

Specific function: Metal-responsive transcriptional regulator that represses transcription of cadA and the czcD-trkA operon by binding specifically to their promoter. Binding of zinc causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 14297; Mature: 14297

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYADSGPDPLPDDQVCLVVEVFRMLADATRVQVLWSLADREMSVNELAEQVGKPAPSVSQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHH
HLAKLRMARLVRTRRDGTTIFYRLENEHVRQLVIDAVFNAEHAGPGIPRHHRAAGGLQSV
HHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AKASATKDVG
HHHHHHCCCC
>Mature Secondary Structure
MYADSGPDPLPDDQVCLVVEVFRMLADATRVQVLWSLADREMSVNELAEQVGKPAPSVSQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHH
HLAKLRMARLVRTRRDGTTIFYRLENEHVRQLVIDAVFNAEHAGPGIPRHHRAAGGLQSV
HHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
AKASATKDVG
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]